Methoxylated Flavones + Goserelin
Goserelin brand name: Zoladex.
We found no known interaction between Methoxylated Flavones and Goserelin in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.
Methoxylated Flavones and Goserelin
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Goserelin and Methoxylated Flavones in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Methoxylated Flavones safety at a glance
Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Why No Interaction Is Listed for Goserelin
Interactions in our licensed database are recorded against drug classes, not just single drug names. Goserelin is filed under a single classification — oral drugs. Methoxylated Flavones has documented interactions with 5 drug classes — the most serious being anticoagulant/antiplatelet drugs (moderate), cytochrome p450 1a2 (cyp1a2) substrates (moderate) and cytochrome p450 3a4 (cyp3a4) substrates (moderate) — and none of Goserelin’s classifications are among them.
Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.
Methoxylated Flavones Does Interact With Other Medications
Methoxylated Flavones has 892 moderate known drug interactions in our database — Goserelin isn’t one of them. If you take anything else, check it against the full list below.
Check Another of Your Medications Against Methoxylated Flavones
We haven’t checked that one against Methoxylated Flavones yet — ask our pharmacists directly.
Covers the 2,830 medications we’ve checked against Methoxylated Flavones. Pick one to open its full report.
Methoxylated Flavones in Pregnancy & Breastfeeding
When consumed orally in amounts typically found in foods. There is insufficient reliable information available about the safety of methoxylated flavones when used in amounts greater than those found in foods during pregnancy or breast-feeding; avoid using in amounts greater than those typically found in foods.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center
See Every Supplement That Interacts With Goserelin
This page covers Methoxylated Flavones only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Goserelin page lists 17 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).
By severity: 1 major · 7 moderate · 9 minor.
From our pharmacist’s overview on the Goserelin page
“Goserelin (Zoladex) is given as a small implant under the skin, usually for prostate cancer, certain breast cancers, or endometriosis, and I would want anyone on it to read this list with real attention. All 17 flagged ingredients raise the same basic concern, changing how drugs are absorbed or retained, and the single major-rated one…”
Reviewed by 2 · Jul 18, 2026
Where Methoxylated Flavones and Goserelin Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#1,048 of 1,452 supplements looked up here in the last 7 days
#2,335 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Methoxylated Flavones reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Methoxylated Flavones and Goserelin records this page draws on were last updated June 22, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Methoxylated Flavones
What is Methoxylated Flavones?
- Antioxidant support
- Circulation and blood vessel health
- Anti-inflammatory support
- Skin and aging support
- General 'metabolism' or wellness blends
Methoxylated flavones (often called polymethoxyflavones) are a group of plant compounds, found mainly in citrus peel, that include substances like nobiletin and tangeretin. Lab and animal studies suggest possible antioxidant and anti-inflammatory effects, but solid human research is very limited, so their real-world benefits are unproven. Talk with a pharmacist or doctor before using them, especially if you take medicines or are pregnant or breastfeeding.
Plant-derived flavonoids (often from citrus peel and other plants) · Capsules, tablets, powders, and combination flavonoid supplements
An interaction check asks whether these two react with each other — it does not ask whether Methoxylated Flavones is a good idea for someone in your situation. Here is what our Methoxylated Flavones record says about it on its own.
Methoxylated Flavones: dosing
There is no established standard dose for methoxylated flavones. Products vary widely in how much they contain and what other ingredients they are combined with.If you choose to use one, follow the directions on the product label and do not exceed the recommended amount.
From our Methoxylated Flavones monograph — the full record covers uses, side effects and every documented interaction.
About Goserelin Implant
What Is Goserelin Implant Used For?
Brand name: Zoladex
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Goserelin implant is used in combination with radiation therapy and other medications to treat localized prostate cancer and is used alone to treat the symptoms associated with advanced prostate cancer. It is also used to treat advanced breast cancer in certain women. It is also used to manage endometriosis (a condition in which the type of tissue that lines the uterus [womb] grows in other areas of the body and causes pain, heavy or irregular menstruation [periods], and other symptoms) and to help with the treatment of abnormal bleeding of the uterus. Goserelin implant is in a class of medications called gonadotropin-releasing hormone (GnRH) agonists. It works by decreasing the amount of certain hormones in the body.
Most-Reported Side Effects for Goserelin
From FAERS, the FDA’s public side-effect reporting system (13,351 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.
Other Drugs & Methoxylated Flavones
Browse every other medication we’ve checked against Methoxylated Flavones — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
892 interactions
- Diclofenac Sodium ›
- Diltiazem ›
- Theophylline ›
- Nifedipine ›
- Ibuprofen ›
- Aspirin ›
- Hydrocortisone ›
- Naproxen ›
- Doxycycline ›
- Erythromycin ›
- Estradiol ›
- Minocycline ›
- Propranolol ›
- Tetracycline ›
- Lidocaine ›
- Ranitidine ›
- Norethindrone ›
- Testosterone ›
- Verapamil ›
- Levonorgestrel ›
- Prednisone ›
- Quinidine ›
- Cyclosporine ›
- Dexamethasone ›
- Glyburide ›
- Triazolam ›
- Zopiclone ›
- Ciprofloxacin ›
- Colchicine ›
- Fentanyl ›
- Oxybutynin ›
- Prednisolone ›
- Tacrolimus ›
- Temazepam ›
- Triamcinolone ›
- Apomorphine ›
- Budesonide ›
- Carbamazepine ›
- Clindamycin ›
- Dextromethorphan ›
- Diclofenac Potassium ›
- Dipyridamole ›
- Doxorubicin ›
- Fluticasone ›
- Miconazole ›
- Morphine Sulfate ›
- Acetaminophen ›
- Buprenorphine ›
- Conjugated Estrogens ›
- Diazepam ›
- Everolimus ›
- Ivabradine ›
- Ivermectin ›
- Ketoprofen ›
- Lofepramine ›
- Medroxyprogesterone ›
- Medroxyprogesterone Acetate ›
- Methotrexate ›
- Nortriptyline ›
- Ofloxacin ›
Showing 60 of 892 moderate interactions — see all 892 on the Methoxylated Flavones page.
No interaction 1,937 drugs checked — show the list
We also checked Methoxylated Flavones against these medications and found no known interaction in our sources. Open any page to confirm.
- Levothyroxine ›
- Methylphenidate ›
- Metoprolol ›
- Rosuvastatin ›
- Escitalopram ›
- Docusate ›
- Methamphetamine ›
- Tirzepatide ›
- Valacyclovir ›
- Hydroxyurea ›
- Sumatriptan ›
- Semaglutide ›
- Lisdexamfetamine ›
- Metformin ›
- Amoxicillin ›
- Isotretinoin ›
- Lisinopril ›
- Amphetamine ›
- Bupropion ›
- Fluoxetine ›
- Azithromycin ›
- Acyclovir ›
- Pregabalin ›
- Lamotrigine ›
- Dextroamphetamine ›
- Gabapentin ›
- Levothyroxine, Liothyronine ›
- Duloxetine ›
- Methylene Blue ›
- Bisoprolol ›
- Candesartan Cilexetil ›
- Amoxicillin, Clavulanate Potassium ›
- Acetaminophen, Dextromethorphan, Doxylamine ›
- Cephalexin ›
- Cyclopentolate ›
- Ezetimibe ›
- Mannitol ›
- Roxithromycin ›
- Carbidopa, Levodopa ›
- Levetiracetam ›
- Phentermine, Topiramate ›
- Thyroid Hormone ›
- Spironolactone ›
- Levodopa ›
- Dexmethylphenidate ›
- Levothyroxine Sodium ›
- Valsartan ›
- Pizotifen ›
- Daptomycin ›
- Canagliflozin, Metformin ›
- Flutemetamol F-18 ›
- Lenvatinib ›
- Venlafaxine ›
- Hexobarbitone ›
- Cefaclor ›
- Mitomycin ›
- Insulin Degludec, Liraglutide ›
- Magnesium Hydroxide (otc Drug) ›
- Hydroxychloroquine ›
- Pegunigalsidase Alfa-iwxj ›
Showing the 60 most looked-up of 1,937 medications checked with no known interaction — see the full Methoxylated Flavones list.
Methoxylated Flavones References
The 7 references that drive our Methoxylated Flavones monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Middleton E, Kandaswami C, Theoharides TC. The effects of plant flavonoids on mammalian cells: implications for inflammation, heart disease, and cancer. Pharmacol Rev 2000;52:673-751. DOI
- Robbins RC. Effect of methoxylated flavones on erythrocyte aggregation and sedimentation in blood of normal subjects: Evidence of a dietary role for flavonoids. Internat J Vit Nutr Res 1973;43:494-503.
- Robbins RC. In vitro effects of penta-, hexa-, and hepta-methoxylated flavones on aggregation of cells in blood from hospitalized patients. J Clin Pharmacol 1973;13:271-5. PubMed
- Takanaga H, Ohnishi A, Yamada S, et al. Polymethoxylated flavones in orange juice are inhibitors of P-glycoprotein but not cytochrome P450 3A4. J Pharmacol Exp Ther 2000;293:230-6. DOI
- Feng SL, Yuan ZW, Yao XJ, et al. Tangeretin, a citrus pentamethoxyflavone, antagonizes ABCB1-mediated multidrug resistance by inhibiting its transport function. Pharmacol Res 2016;110:193-204. PubMed
- Li Y, Ning J, Wang Y, et al. Drug interaction study of flavonoids toward CYP3A4 and their quantitative structure activity relationship (QSAR) analysis for predicting potential effects. Toxicol Lett. 2018 Sep 15;294:27-36. PubMed
- Bajraktari-Sylejmani G, Weiss J. Potential risk of food-drug interactions: Citrus polymethoxyflavones and flavanones as inhibitors of the organic anion transporting polypeptides (OATP) 1B1, 1B3, and 2B1. Eur J Drug Metab Pharmacokinet. 2020;45(6):809-815. PubMed
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Taking Methoxylated Flavones and Goserelin Together: Common Questions
Is it safe to take Methoxylated Flavones with Goserelin?
How was the Methoxylated Flavones and Goserelin combination checked?
Does Methoxylated Flavones interact with any other medications?
Does Goserelin interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.