Drug & supplement interaction

Pulsed Electromagnetic Field (pemf) Therapy + Tolbutamide

Tolbutamide brand name: Orinase.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Pulsed Electromagnetic Field (pemf) Therapy and Tolbutamide in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Pulsed Electromagnetic Field (pemf) Therapy and Tolbutamide

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Tolbutamide and Pulsed Electromagnetic Field (pemf) Therapy in our sources. This does not guarantee that the combination is completely free of risk — research on Pulsed Electromagnetic Field (pemf) Therapy alongside specific medications may be limited.

Worth understanding: our licensed dataset holds no drug-interaction record for Pulsed Electromagnetic Field (pemf) Therapy at all — not against Tolbutamide, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

Pulsed Electromagnetic Field (pemf) Therapy is a treatment rather than something you take. Tell whoever provides it which medicines you use, and ask your prescriber whether it is appropriate for your health and treatment. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Pulsed Electromagnetic Field (pemf) Therapy safety at a glance

Pulsed Electromagn... overall Use caution Generally well tolerated for most people, but not appropriate for everyone, especially those with implanted electronic devices.
Pregnancy Avoid Safety during pregnancy has not been established, so it is best avoided unless directed by a doctor.
Breastfeeding Not established There is little research on PEMF use while breastfeeding, so caution is advised.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Tolbutamide and Pulsed Electromagnetic Field (pemf) Therapy? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Pulsed Electromagnetic Field (pemf) Therapy Itself Has Been Linked To

This is not an interaction — nothing below involves Tolbutamide. It is the side-effect record for Pulsed Electromagnetic Field (pemf) Therapy on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Pulsed Electromagnetic Field (pemf) Therapy, this list is the first place to look. One entry is worth acting on rather than waiting out — marked below.

  • Raised blood pressure Worth acting on Additional detail

    “In one study, two patients given PEMF treatment had orthostatic hypertension which resolved upon treatment discontinuation.”

    Pulsed Electromagnetic Field (pemf) Therapy · Natural Medicines adverse-effect record, reported in hypertension.

    1 source cited
    1. 109144. Sutbeyaz ST, Sezer N, Koseoglu F, Kibar S. Low-frequency pulsed electromagnetic field therapy in fibromyalgia: a randomized, double-blind, sham-controlled clinical study. Clin J Pain. 2009;25(8):722-8. PubMed

Everything above comes from the Natural Medicines adverse-effect record for Pulsed Electromagnetic Field (pemf) Therapy — expand a row for the licensed statement it rests on. We haven’t matched Tolbutamide to its FDA label in our system yet, so we can’t compare its own side-effect list here — the leaflet that comes with your prescription is the authoritative list for Tolbutamide.

Everything else you take

See Every Supplement That Interacts With Tolbutamide

This page covers Pulsed Electromagnetic Field (pemf) Therapy only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Tolbutamide page lists 305 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Siberian Cocklebur (major), Acai (moderate), Adrafinil (moderate) and African Wild Potato (moderate).

By severity: 2 major · 255 moderate · 48 minor.

From our pharmacist’s overview on the Tolbutamide page

“People take tolbutamide (Orinase) to lower blood sugar in type 2 diabetes, and diabetes is exactly the condition supplement shelves target, which is why this list runs to 305 ingredients and deserves real caution. Of those, 239 also push glucose around, most often downward, so combining them can drive sugar lower than intended.”

Reviewed by 2 · Jul 18, 2026

Open the Tolbutamide interaction page

How much people look this up

Where Pulsed Electromagnetic Field (pemf) Therapy and Tolbutamide Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Pulsed Electromagnetic Field (pemf) Therapy
Steady interest

#1,310 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Tolbutamide
Steady interest

#2,229 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Pulsed Electromagnetic Field (pemf) Therapy reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Pulsed Electromagnetic Field (pemf) Therapy and Tolbutamide records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Treatment approach

About Pulsed Electromagnetic Field (pemf) Therapy

What is Pulsed Electromagnetic Field (pemf) Therapy?

  • Bone healing (fractures and non-unions)
  • Osteoarthritis and joint pain
  • General pain and inflammation
  • Muscle recovery and stiffness
  • Wound healing
  • Sleep and relaxation

PEMF therapy uses pulsing electromagnetic fields from a device to try to ease pain and support tissue or bone healing. The strongest evidence is for certain bone-healing uses, where it is FDA-cleared; for most other claims the evidence is limited or mixed. It is generally well tolerated, but people with implanted electronic devices and those who are pregnant should avoid it unless a doctor approves.

Not applicable (a device-based therapy, not an herb or supplement) · Mats, pads, rings, handheld wands, and full-body devices that deliver electromagnetic pulses

An interaction check asks whether these two react with each other — it does not ask whether Pulsed Electromagnetic Field (pemf) Therapy is a good idea for someone in your situation. Here is what our Pulsed Electromagnetic Field (pemf) Therapy record says about it on its own.

Pulsed Electromagnetic Field (pemf) Therapy: dosing

There is no single standard dose for PEMF therapy. Settings such as frequency, intensity, session length, and how often to use the device vary widely between products and conditions.For medical-grade devices used for bone healing, the doctor or device maker provides a specific treatment schedule.

From our Pulsed Electromagnetic Field (pemf) Therapy monograph — the full record covers uses, side effects and every documented interaction.

Read the full Pulsed Electromagnetic Field (pemf) Therapy monograph & all interactions
Medication

About Tolbutamide

What Is Tolbutamide Used For?

Brand name: Orinase

  • Tolbutamide is used along with diet and exercise, and sometimes with other medications, to treat type 2 diabetes (condition in which the body does not use insulin normally and, therefore, cannot control the amount of sugar in the blood). Tolbutamide is in a class of medications called sulfonylureas. Tolbutamide lowers blood sugar by causing the pancreas to produce insulin (a natural substance that is needed to break down sugar in the body) and helping the body use insulin efficiently. This medication will only help lower blood sugar in people whose bodies produce insulin naturally. Tolbutamide is not used to treat type 1 diabetes (condition in which the body does not produce insulin and, therefore, cannot control the amount of sugar in the blood) or diabetic ketoacidosis (a serious condition that may occur if high blood sugar is not treated).

  • Over time, people who have diabetes and high blood sugar can develop serious or life-threatening complications, including heart disease, stroke, kidney problems, nerve damage, and eye problems. Taking medication(s), making lifestyle changes (e.g., diet, exercise, quitting smoking), and regularly checking your blood sugar may help to manage your diabetes and improve your health. This therapy may also decrease your chances of having a heart attack, stroke, or other diabetes-related complications such as kidney failure, nerve damage (numb, cold legs or feet; decreased sexual ability in men and women), eye problems, including changes or loss of vision, or gum disease. Your doctor and other healthcare providers will talk to you about the best way to manage your diabetes.

See full Tolbutamide drug information
Keep checking

Other Drugs & Pulsed Electromagnetic Field (pemf) Therapy

Browse every other medication we’ve checked against Pulsed Electromagnetic Field (pemf) Therapy — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Pulsed Electromagnetic Field (pemf) Therapy References

The 1 references that drive our Pulsed Electromagnetic Field (pemf) Therapy monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Sutbeyaz ST, Sezer N, Koseoglu F, Kibar S. Low-frequency pulsed electromagnetic field therapy in fibromyalgia: a randomized, double-blind, sham-controlled clinical study. Clin J Pain. 2009;25(8):722-8. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Having Pulsed Electromagnetic Field (pemf) Therapy While Taking Tolbutamide: Common Questions

Is it safe to have Pulsed Electromagnetic Field (pemf) Therapy while taking Tolbutamide?
We do not list a known interaction between Pulsed Electromagnetic Field (pemf) Therapy and Tolbutamide. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Tolbutamide interact with any supplements?
Yes. Tolbutamide has documented interactions with 305 supplements in our database — Pulsed Electromagnetic Field (pemf) Therapy is not one of them. The Tolbutamide interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Tolbutamide and Pulsed Electromagnetic Field (pemf) Therapy?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.