Resveratrol + Aspirin, Carisoprodol, Codeine Phosphate
Aspirin, Carisoprodol, Codeine Phosphate brand name: Soma Compound w/ Codeine.
Aspirin, Carisoprodol, Codeine Phosphate falls into 2 drug categories that Resveratrol can interact with; the most serious is rated moderate. Theoretically, resveratrol might increase levels of drugs metabolized by CYP2C19.
Read the full interaction reportResveratrol and Aspirin, Carisoprodol, Codeine Phosphate
These two interact in 2 distinct ways. Each one is explained separately below.
Why Are There 2 Interactions?
Resveratrol interacts with whole categories of medication. Aspirin, Carisoprodol, Codeine Phosphate falls into 2 of those categories, so it can interact with Resveratrol in 2 different ways. We’ve listed each one below — your overall risk is driven by the most serious of them (Moderate).
CYTOCHROME P450 2C19 (CYP2C19) SUBSTRATES
1 of 2Why this applies to Aspirin, Carisoprodol, Codeine Phosphate
Aspirin, Carisoprodol, Codeine Phosphate falls under CYTOCHROME P450 2C19 (CYP2C19) SUBSTRATES — the group Resveratrol interacts with.
In vitro research shows that resveratrol can inhibit CYP2C19 enzymes. However, this interaction has not been reported in humans.
Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.
Here's the gist with this combination pill (aspirin, carisoprodol, and codeine). The piece that lines up with resveratrol is carisoprodol, the muscle relaxant, which your body partly breaks down using an enzyme called CYP2C19. In test-tube studies, resveratrol can slow that enzyme down. In theory, that could let carisoprodol build up a bit, which might mean more drowsiness, dizziness, or grogginess than usual.
I want to keep this in perspective, though. This is based only on lab research, not real-world reports in people, so it may not amount to much, especially at typical supplement doses. Still, since this product already causes sedation (from both the muscle relaxant and codeine), it's worth a quick chat with your pharmacist or doctor before adding resveratrol.
- Yu, C., Shin, Y. G., Kosmeder, J. W., Pezzuto, J. M., and van Breemen, R. B. Liquid chromatography/tandem mass spectrometric determination of inhibition of human cytochrome P450 isozymes by resveratrol and resveratrol-3-sulfate. Rapid Commun.Mass Spectro PubMed
ANTICOAGULANT/ANTIPLATELET DRUGS
2 of 2Aspirin, Carisoprodol, Codeine Phosphate also falls under ANTICOAGULANT/ANTIPLATELET DRUGS.
Resveratrol seems to have antiplatelet effects.
Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.
This combo pill contains aspirin, which already thins your blood by making your platelets less sticky. Resveratrol seems to have a mild blood-thinning effect of its own, so taking the two together could add up and make it a little easier to bruise or bleed. Think along the lines of nosebleeds, bleeding gums, or cuts that take longer to stop.
The good news is this concern comes mostly from lab and animal studies, not strong human research, so the real-world risk at normal doses is likely small. Still, the effect is worth watching, especially if you take aspirin daily or are headed for surgery or dental work. Please check with your pharmacist or doctor before adding a resveratrol supplement so you can keep an eye out together.
- Pace-Asciak CR, Rounova O, Hahn SE, et al. Wines and grape juices as modulators of platelet aggregation in healthy human subjects. Clin Chim Acta 1996;246:163-82. PubMed
- Bertelli AA, Giovannini L, Bernini W, et al. Antiplatelet activity of cis-resveratrol. Drugs Exp Clin Res 1996;22:61-3.
- Pace-Asciak CR, Hahn S, Diamandis EP, et al. The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation and eicosanoid synthesis: implications for protection against coronary heart disease. Clin Chim Acta 1995;235:207-19.
- Bertelli A, Bertelli AA, Gozzini A, Giovannini L. Plasma and tissue resveratrol concentrations and pharmacological activity. Drugs Exp Clin Res 1998;24:133-8.
- Bertelli AA, Giovannini L, Giannessi D, et al. Antiplatelet activity of synthetic and natural resveratrol in red wine. Int J Tissue React 1995;17:1-3.
- Dobrydneva, Y., Williams, R. L., and Blackmore, P. F. trans-Resveratrol inhibits calcium influx in thrombin-stimulated human platelets. Br.J.Pharmacol. 1999;128(1):149-157.
- Kirk, R. I., Deitch, J. A., Wu, J. M., and Lerea, K. M. Resveratrol decreases early signaling events in washed platelets but has little effect on platalet in whole food. Blood Cells Mol.Dis. 2000;26(2):144-150.
- Zbikowska, H. M. and Olas, B. Antioxidants with carcinostatic activity (resveratrol, vitamin E and selenium) in modulation of blood platelet adhesion. J Physiol Pharmacol. 2000;51(3):513-520.
- Olas, B., Wachowicz, B., Saluk-Juszczak, J., and Zielinski, T. Effect of resveratrol, a natural polyphenolic compound, on platelet activation induced by endotoxin or thrombin. Thromb.Res 8-15-2002;107(3-4):141-145. PubMed
- Ma, Z. H. and Ma, Q. Y. Resveratrol: a medical drug for acute pancreatitis. World J Gastroenterol. 6-7-2005;11(21):3171-3174. PubMed
- Pendurthi, U. R., Williams, J. T., and Rao, L. V. Resveratrol, a polyphenolic compound found in wine, inhibits tissue factor expression in vascular cells : A possible mechanism for the cardiovascular benefits associated with moderate consumption of wine. PubMed
What These Ratings Mean
Every interaction above is graded three ways — here’s the key to each label.
Clinically significant. Avoid the combination, or use only under close professional supervision.
Usually worth avoiding or managing — may need monitoring, a dose change, or timing apart.
Generally not serious. Be aware of it and mention it to your pharmacist.
- LikelyWell-controlled human studies have demonstrated the likely existence of this interaction.
- ProbableInteraction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
- PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.
- UnlikelyInteraction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
- AHigh-quality meta-analysis (quantitative systematic review).
- BCase-control study.
- CConsensus.
- DAnecdotal evidence.
These ratings are for information only. Never start, stop, or otherwise change your therapy before speaking with your provider.
Resveratrol Also Interacts With Other Medications
Resveratrol has 821 moderate known drug interactions in our database — the Aspirin, Carisoprodol, Codeine Phosphate one above is among them. If you take anything else, check it against the full list below.
Check Another of Your Medications Against Resveratrol
We haven’t checked that one against Resveratrol yet — ask our pharmacists directly.
Covers the 2,830 medications we’ve checked against Resveratrol. Pick one to open its full report.
Questions About Resveratrol or Aspirin, Carisoprodol, Codeine Phosphate
These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Resveratrol or Aspirin, Carisoprodol, Codeine Phosphate, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:
Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.
See Every Supplement That Interacts With Aspirin, Carisoprodol, Codeine Phosphate
This page covers Resveratrol only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Aspirin, Carisoprodol, Codeine Phosphate page lists 339 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: 1,4-butanediol (major), Activated Charcoal (major), Asarabacca (major), Beer (major) and Danshen (major).
By severity: 11 major · 292 moderate · 36 minor.
From our pharmacist’s overview on the Aspirin, Carisoprodol, Codeine Phosphate page
“Soma Compound with Codeine packs aspirin, carisoprodol, and codeine into one tablet, and I read its list of 339 interacting supplement ingredients as a genuine warning, not fine print. Most, 202 of them, can add to aspirin's blood-thinning effect and raise bleeding risk.”
Reviewed by 2 · Jul 18, 2026
Open the Aspirin, Carisoprodol, Codeine Phosphate interaction page
Taking Resveratrol as Part of a Dietary Supplement Product? Check It for Interactions
We hold 2,939 real supplement products containing Resveratrol, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Resveratrol. Your product may carry other ingredients that interact with Aspirin, Carisoprodol, Codeine Phosphate too, on top of Resveratrol — and those would not show on this page. Find your product and we’ll check every ingredient on its label:
Where Resveratrol and Aspirin, Carisoprodol, Codeine Phosphate Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#87 of 1,452 supplements looked up here in the last 7 days
#390 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
About Resveratrol
What is Resveratrol?
- Heart and blood vessel health
- Antioxidant support
- Anti-aging
- Blood sugar and metabolic support
- General anti-inflammatory support
Resveratrol is a plant compound found in red grapes, berries, and peanuts that is popular for heart health, anti-aging, and antioxidant support. While lab and animal studies are promising, strong human evidence for most uses is still limited. It appears generally well tolerated in supplement doses, but talk with your pharmacist or doctor before starting it.
Other Drugs & Resveratrol
Browse every other medication we’ve checked against Resveratrol — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
821 interactions
- Diclofenac Sodium ›
- Diltiazem ›
- Theophylline ›
- Nifedipine ›
- Ibuprofen ›
- Aspirin ›
- Hydrocortisone ›
- Naproxen ›
- Erythromycin ›
- Estradiol ›
- Minocycline ›
- Propranolol ›
- Lidocaine ›
- Norethindrone ›
- Testosterone ›
- Verapamil ›
- Levonorgestrel ›
- Prednisone ›
- Quinidine ›
- Cyclosporine ›
- Dexamethasone ›
- Triazolam ›
- Zopiclone ›
- Colchicine ›
- Fentanyl ›
- Oxybutynin ›
- Phenytoin ›
- Prednisolone ›
- Tacrolimus ›
- Temazepam ›
- Budesonide ›
- Carbamazepine ›
- Clindamycin ›
- Dextromethorphan ›
- Diclofenac Potassium ›
- Dipyridamole ›
- Doxorubicin ›
- Fluticasone ›
- Formoterol ›
- Miconazole ›
- Acetaminophen ›
- Buprenorphine ›
- Conjugated Estrogens ›
- Diazepam ›
- Everolimus ›
- Ivabradine ›
- Ketoprofen ›
- Lofepramine ›
- Medroxyprogesterone ›
- Medroxyprogesterone Acetate ›
- Nortriptyline ›
- Rifampin ›
- Testosterone Undecanoate ›
- Aripiprazole ›
- Bendamustine ›
- Bivalirudin ›
- Caffeine (otc Drug) ›
- Ciclesonide ›
- Clonazepam ›
- Cyclobenzaprine ›
Showing 60 of 821 moderate interactions — see all 821 on the Resveratrol page.
No interaction 2,008 drugs checked — show the list
We also checked Resveratrol against these medications and found no known interaction in our sources. Open any page to confirm.
- Levothyroxine ›
- Methylphenidate ›
- Ivermectin ›
- Rosuvastatin ›
- Metoprolol ›
- Escitalopram ›
- Methamphetamine ›
- Tirzepatide ›
- Isotretinoin ›
- Docusate ›
- Sumatriptan ›
- Valacyclovir ›
- Hydroxyurea ›
- Semaglutide ›
- Metformin ›
- Lisdexamfetamine ›
- Amphetamine ›
- Methotrexate ›
- Amoxicillin ›
- Lisinopril ›
- Levothyroxine, Liothyronine ›
- Bupropion ›
- Fluoxetine ›
- Doxycycline ›
- Azithromycin ›
- Pregabalin ›
- Lamotrigine ›
- Dextroamphetamine ›
- Acyclovir ›
- Gabapentin ›
- Duloxetine ›
- Methylene Blue ›
- Ciprofloxacin ›
- Candesartan Cilexetil ›
- Amoxicillin, Clavulanate Potassium ›
- Bisoprolol ›
- Ezetimibe ›
- Cyclopentolate ›
- Cephalexin ›
- Insulin Degludec, Liraglutide ›
- Calcium Oxybate, Magnesium Oxybate, Potassium Oxybate, Sodium Oxybate ›
- Thyroid Hormone ›
- Mannitol ›
- Levetiracetam ›
- Levodopa ›
- Roxithromycin ›
- Carbidopa, Levodopa ›
- Alginic Acid, Aluminum Hydroxide ›
- Acetaminophen, Dextromethorphan, Doxylamine ›
- Isoniazid, Pyrazinamide, Rifampin ›
- Spironolactone ›
- Valsartan ›
- Mitomycin ›
- Magnesium Hydroxide (otc Drug) ›
- Sacubitril, Valsartan ›
- Atenolol, Chlorthalidone ›
- Canagliflozin, Metformin ›
- Bupivacaine, Meloxicam ›
- Venlafaxine ›
- Atenolol ›
Showing the 60 most looked-up of 2,008 medications checked with no known interaction — see the full Resveratrol list.
Sources & How We Checked
Interaction details are evidence-graded and sourced from the Natural Medicines database. The medication overview comes from MedlinePlus.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference for vitamins, herbs and supplements — the basis for our interaction data.
- MedlinePlus, U.S. National Library of Medicine — NIH consumer drug information, used for the medication overviews.
- NIH Dietary Supplement Label Database (DSLD) — Official supplement product labels.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Aspirin, Carisoprodol, Codeine Phosphate Is Linked to Lower Levels of 3 Nutrients
Natural Medicines records Aspirin, Carisoprodol, Codeine Phosphate as a medicine that can lower these. This is not an interaction with Resveratrol — it is a separate effect of the medicine, and it is a reason some people are advised to supplement rather than to avoid one:
Read the full Aspirin, Carisoprodol, Codeine Phosphate nutrient depletion report ›
Depletion records come from the licensed Natural Medicines database. Do not start a supplement on the strength of this page — ask your pharmacist or doctor whether it applies to you.
Taking Resveratrol and Aspirin, Carisoprodol, Codeine Phosphate Together: Common Questions
Can you take Resveratrol with Aspirin, Carisoprodol, Codeine Phosphate?
Why are there 2 interactions listed for Resveratrol and Aspirin, Carisoprodol, Codeine Phosphate?
How serious is the Resveratrol and Aspirin, Carisoprodol, Codeine Phosphate interaction?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.