Drug & supplement interaction

Rice Protein + Octreotide

Octreotide brand names: Sandostatin, Mycapssa.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Rice Protein and Octreotide in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Octreotide states a food rule worth keeping to, and the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Rice Protein and Octreotide

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Octreotide and Rice Protein in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Rice Protein safety at a glance

Rice Protein overall Generally safe Rice protein is generally considered safe for most healthy adults when used as a food.
Pregnancy Use caution Whole food rice is fine, but concentrated supplements are not well studied in pregnancy, so check with your provider first.
Breastfeeding Use caution Likely fine as a food, but concentrated protein supplements are not well studied while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Octreotide and Rice Protein? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Octreotide

Interactions in our licensed database are recorded against drug classes, not just single drug names. Octreotide is filed under 2 classifications — cytochrome p450 3a4 (cyp3a4) inhibitors, oral drugs. Rice Protein has documented interactions with 1 drug class — the most serious being ace inhibitors (aceis) (moderate) — and none of Octreotide’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Rice Protein Does Interact With Other Medications

Rice Protein has 23 moderate known drug interactions in our database — Octreotide isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Rice Protein

Covers the 2,830 medications we’ve checked against Rice Protein. Pick one to open its full report.

What to actually watch for

No Interaction Found — But Data Suggests Rice Protein and Octreotide May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • Tiredness / Diarrhea / Vomiting Additional detail

    Rice Protein

    “Orally, rice protein has been rarely reported to cause enterocolitis symptoms of vomiting, diarrhea, and dehydration, possibly leading to acidosis and lethargy, in infants and young children. Rarely, enterocolitis symptoms are associated with an allergy to rice protein.”

    Rice Protein · Natural Medicines adverse-effect record, reported in allergic rhinitis (hay fever).

    2 sources cited
    1. 97806. Yasutomi M, Kosaka T, Kawakita A, et al. Rice protein-induced enterocolitis syndrome with transient specific IgE to boiled rice but not to retort-processed rice. Pediatr Int. 2014;56(1):110-2.
    2. 97811. Hojsak I, Kljaic-Turkalj M, Misak Z, Kolacek S. Rice protein-induced enterocolitis syndrome. Clin Nutr. 2006;25(3):533-6. PubMed

    Octreotide

    Listed in the ADVERSE REACTIONS section of the FDA label for Octreotide. Read the label on DailyMed ›

Reported for Rice Protein but not commonly for Octreotide: dehydration.

Effects for Octreotide come from the ADVERSE REACTIONS section of its FDA label; effects for Rice Protein come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

How to take them

Some Octreotide Products Have a Food Rule — Rice Protein Should Not Break It

At least one FDA label for a product containing Octreotide says to take it on an empty stomach. Most supplements — Rice Protein included — are taken with a meal, so the easy mistake is swallowing both together at breakfast. Where that rule applies, keep Octreotide on its own and move Rice Protein to a meal later in the day.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Octreotide products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

2 DOSAGE AND ADMINISTRATION Take MYCAPSSA orally with a glass of water on an empty stomach, at least 1 hour before a meal or at least 2 hours after a meal (‎ 2.1 ).

From the Dosage and Administration section of the FDA label we read for Octreotide — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Everything else you take

See Every Supplement That Interacts With Octreotide

This page covers Rice Protein only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Octreotide page lists 30 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Adrafinil (moderate), Cannabidiol (cbd) (moderate), Cannabinol (cbn) (moderate) and Cannabis (moderate).

By severity: 1 major · 19 moderate · 10 minor.

From our pharmacist’s overview on the Octreotide page

“Take this page with genuine care if you use octreotide (Sandostatin injections or Mycapssa capsules) for acromegaly or hormone-secreting tumors, since steady drug levels are what keep symptoms suppressed. Of the 30 ingredients on file, one rates major, activated charcoal, which can pull octreotide out of circulation and blunt its effec…”

Reviewed by 2 · Jul 18, 2026

Open the Octreotide interaction page

One more smart check

Taking Rice Protein as Part of a Dietary Supplement Product? Check It for Interactions

We hold 610 real supplement products containing Rice Protein, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Rice Protein. Even though Rice Protein itself has no known interaction with Octreotide, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Rice Protein and Octreotide Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Rice Protein
Top 25%

#344 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Octreotide
Steady interest

#2,390 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Rice Protein reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Rice Protein and Octreotide records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Rice Protein

What is Rice Protein?

  • Building and maintaining muscle
  • Post-workout recovery
  • Plant-based protein source
  • Meal replacement and shakes
  • Weight management support

Rice protein is a plant-based protein powder made from rice that offers an easy way to add protein to your diet, especially if you avoid dairy or animal products. It is generally considered safe and well tolerated, though on its own it is lower in the amino acid lysine and is often blended with pea protein for a more complete amino acid profile. Talk to your pharmacist or doctor before using it if you have kidney problems or other health conditions.

Oryza sativa · Poaceae · Seed (grain/endosperm and bran) · Powder, protein shakes, capsules, blended plant-protein products

An interaction check asks whether these two react with each other — it does not ask whether Rice Protein is a good idea for someone in your situation. Here is what our Rice Protein record says about it on its own.

Rice Protein: dosing

There is no official standardized dose for rice protein. Serving sizes are usually based on how much protein you want to add to your diet, commonly around 20 to 30 grams of protein per scoop, but this varies by product.Always follow the directions on the product label and consider your total daily protein needs from all foods.

From our Rice Protein monograph — the full record covers uses, side effects and every documented interaction.

Read the full Rice Protein monograph & all interactions
Medication

About Octreotide

What Is Octreotide Used For?

Brand names: Sandostatin, Mycapssa

Octreotide injection (available as Sandostatin, BYNFEZIA Pen, and other octreotide acetate injection products) is used to lower abnormally high growth hormone and IGF-1 levels in acromegaly, and to reduce the severe diarrhea and flushing associated with metastatic carcinoid tumors and the profuse watery diarrhea caused by VIPomas (vasoactive intestinal peptide-secreting tumors).

Mycapssa, the oral delayed-release capsule, is approved specifically for long-term maintenance treatment of acromegaly in patients who have already responded to and tolerated treatment with octreotide or lanreotide injections. It is not indicated for carcinoid tumors or VIPomas.

See full Octreotide drug information
Keep checking

Other Drugs & Rice Protein

Browse every other medication we’ve checked against Rice Protein — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
23Moderate
0Minor
2,806No known interaction
Moderate

23 interactions

No interaction 2,806 drugs checked — show the list
Evidence & sources

Rice Protein References

The 6 references that drive our Rice Protein monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Joy JM, Lowery RP, Wilson JM, et al. The effects of 8 weeks of whey or rice protein supplementation on body composition and exercise performance. Nutr J 2013;12:86. PubMed
  2. Li GH, Qu MR, Wan JZ, You JM. Antihypertensive effect of rice protein hydrolysate with in vitro angiotensin I-converting enzyme inhibitory activity in spontaneously hypertensive rats. Asia Pac J Clin Nutr. 2007;16 Suppl 1:275-80.
  3. Reche M, Pascual C, Fiandor A, et al. The effect of a partially hydrolysed formula based on rice protein in the treatment of infants with cow's milk protein allergy. Pediatr Allergy Immunol. 2010;21(4 Pt 1):577-85. PubMed
  4. Amended final report on the safety assessment of Oryza sativa (rice) bran oil, Oryza sativa (rice) germ oil, rice bran acid, Oryza sativa (rice) bran wax, hydrogenated rice bran wax, Oryza sativa (rice) bran extract, Oryza sativa (rice) extract, Oryza sat
  5. Yasutomi M, Kosaka T, Kawakita A, et al. Rice protein-induced enterocolitis syndrome with transient specific IgE to boiled rice but not to retort-processed rice. Pediatr Int. 2014;56(1):110-2.
  6. Hojsak I, Kljaic-Turkalj M, Misak Z, Kolacek S. Rice protein-induced enterocolitis syndrome. Clin Nutr. 2006;25(3):533-6. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Rice Protein and Octreotide Together: Common Questions

Is it safe to take Rice Protein with Octreotide?
We do not list a known interaction between Rice Protein and Octreotide. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Rice Protein and Octreotide have any of the same side effects?
Yes — our sources link each of them separately to 3 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Should I take Rice Protein and Octreotide at the same time of day?
At least one FDA label for a product containing Octreotide says to take it on an empty stomach, and supplements are usually taken with a meal — so taking them together at breakfast is the easy mistake. Where that applies, keep Octreotide on its own and move Rice Protein to a meal later in the day. Food instructions belong to the product rather than the ingredient, so check the directions on your own box. This is about absorption, not an interaction.
How was the Rice Protein and Octreotide combination checked?
Interactions in our licensed database are recorded against drug classes. Octreotide is filed under 2 classifications, and Rice Protein has documented interactions with 1 drug class — none of Octreotide's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Rice Protein interact with any other medications?
Yes. Rice Protein has 23 documented drug interactions in our database — Octreotide is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Octreotide interact with any supplements?
Yes. Octreotide has documented interactions with 30 supplements in our database — Rice Protein is not one of them. The Octreotide interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Octreotide and Rice Protein?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.