Drug & supplement interaction

Strophanthus + Isavuconazonium Sulfate (IV)

Isavuconazonium Sulfate (IV) brand name: Cresemba.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Strophanthus and Isavuconazonium Sulfate (IV) in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Strophanthus and Isavuconazonium Sulfate (IV)

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Isavuconazonium Sulfate (IV) and Strophanthus in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Strophanthus safety at a glance

Strophanthus overall Avoid Strophanthus contains potent, potentially toxic cardiac glycosides and should only be used under direct medical supervision.
Pregnancy Unsafe When used orally due to possible uterine stimulating effects; avoid using. Read the full pregnancy detail
Breastfeeding Unsafe When used orally; avoid using. Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Isavuconazonium Sulfate (IV) and Strophanthus? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Isavuconazonium Sulfate (IV)

Interactions in our licensed database are recorded against drug classes, not just single drug names. Isavuconazonium Sulfate (IV) is filed under a single classification — cytochrome p450 3a4 (cyp3a4) substrates. Strophanthus has documented interactions with 6 drug classes — the most serious being quinidine (major), quinine (major) and corticosteroids (moderate) — and none of Isavuconazonium Sulfate (IV)’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Strophanthus Does Interact With Other Medications

Strophanthus has 3 major, 120 moderate known drug interactions in our database — Isavuconazonium Sulfate (IV) isn’t one of them. If you take anything else, check it against the full list below.

Major 3 Moderate 120 No known interaction 2,707 (incl. Isavuconazonium Sulfate (IV))
Taking anything else?

Check Another of Your Medications Against Strophanthus

Covers the 2,830 medications we’ve checked against Strophanthus. Pick one to open its full report.

What to actually watch for

No Interaction Found — But Data Suggests Strophanthus and Isavuconazonium Sulfate (IV) May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do. One of them is worth acting on rather than waiting out — marked below.

  • An irregular heartbeat Worth acting on Additional detail

    Strophanthus

    “Orally, side effects include nausea, vomiting, headache, stupor, disturbance of color vision, and cardiac arrhythmias, particularly during overdose (18).”

    Strophanthus · Natural Medicines adverse-effect record, reported in arrhythmia.

    1 source cited
    1. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

    “Orally, side effects include cardiac arrhythmias (18).”

    Strophanthus · Natural Medicines adverse-effect record, reported in arrhythmia.

    1 source cited
    1. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

    Isavuconazonium Sulfate (IV)

    Listed in the ADVERSE REACTIONS section of the FDA label for Isavuconazonium Sulfate (IV). Read the label on DailyMed ›

  • Vomiting / Nausea Additional detail

    Strophanthus

    “Orally, side effects include nausea and vomiting (18).”

    Strophanthus · Natural Medicines adverse-effect record, reported in nausea and vomiting.

    1 source cited
    1. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

    Isavuconazonium Sulfate (IV)

    Listed in the ADVERSE REACTIONS section of the FDA label for Isavuconazonium Sulfate (IV). Read the label on DailyMed ›

  • Headache Additional detail

    Strophanthus

    “Orally, side effects include headache, stupor, and disturbance of color vision (18).”

    Strophanthus · Natural Medicines adverse-effect record, reported in cluster headache.

    1 source cited
    1. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

    Isavuconazonium Sulfate (IV)

    Listed in the ADVERSE REACTIONS section of the FDA label for Isavuconazonium Sulfate (IV). Read the label on DailyMed ›

Effects for Isavuconazonium Sulfate (IV) come from the ADVERSE REACTIONS section of its FDA label; effects for Strophanthus come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Special populations

Strophanthus in Pregnancy & Breastfeeding

Pregnancy Unsafe

When used orally due to possible uterine stimulating effects; avoid using.

Lactation Unsafe

When used orally; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Isavuconazonium Sulfate (IV)

This page covers Strophanthus only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Isavuconazonium Sulfate (IV) page lists 121 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate), Adrafinil (moderate) and African Wild Potato (moderate).

By severity: 2 major · 87 moderate · 32 minor.

Open the Isavuconazonium Sulfate (IV) interaction page

How much people look this up

Where Strophanthus and Isavuconazonium Sulfate (IV) Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Strophanthus
Steady interest

#828 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Isavuconazonium Sulfate (IV)
Steady interest

#2,487 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Strophanthus reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Strophanthus and Isavuconazonium Sulfate (IV) records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Strophanthus

What is Strophanthus?

  • Heart failure
  • Angina (chest pain)
  • Irregular heartbeat
  • Circulation support
  • Traditional African arrow poison (historical)

Strophanthus is a plant that contains powerful heart-affecting compounds called cardiac glycosides (the best known is ouabain/g-strophanthin). Because these substances can strongly affect heart rhythm and are toxic in the wrong amount, Strophanthus is not a casual supplement and should never be used without close medical supervision. Reliable modern evidence for its supplement use is limited.

Strophanthus gratus · Apocynaceae · Seeds (and the seed-derived glycoside ouabain/g-strophanthin) · Oral drops/tinctures, capsules, and historically injectable extracts (mostly outside the U.S.)

An interaction check asks whether these two react with each other — it does not ask whether Strophanthus is a good idea for someone in your situation. Here is what our Strophanthus record says about it on its own.

Strophanthus: dosing

There is no well-established, standardized supplement dose for Strophanthus, and the strength of products can vary a lot. Because the active glycosides are potent and potentially toxic, picking a dose on your own is not safe.If a product is used, follow the exact directions on the label and use it only under the supervision of a qualified healthcare provider. We deliberately do not list specific milligram amounts here.

From our Strophanthus monograph — the full record covers uses, side effects and every documented interaction.

Read the full Strophanthus monograph & all interactions
Medication

About Isavuconazonium

What Is Isavuconazonium Used For?

Brand name: Cresemba

Cresemba (isavuconazonium sulfate) is used to treat two serious, life-threatening fungal infections: invasive aspergillosis and invasive mucormycosis. These infections can spread through the body and are most dangerous in people with weakened immune systems.

Cresemba for injection is approved for adults and children 1 year of age and older. Cresemba capsules are approved for adults and children 6 years of age and older who weigh at least 16 kilograms (about 35 pounds).

See full Isavuconazonium drug information
Keep checking

Other Drugs & Strophanthus

Browse every other medication we’ve checked against Strophanthus — both the ones with a known interaction and the ones without. Select any drug for the full detail.

3Major
120Moderate
0Minor
2,706No known interaction
3 Major 120 Moderate 2,706 No interaction
Major

3 interactions

Moderate

120 interactions

Showing 60 of 120 moderate interactions — see all 120 on the Strophanthus page.

No interaction 2,706 drugs checked — show the list

We also checked Strophanthus against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,706 medications checked with no known interaction — see the full Strophanthus list.

See the full Strophanthus interactions page
See every supplement checked against Isavuconazonium Sulfate (IV), ranked by severity
Evidence & sources

Strophanthus References

The 4 references that drive our Strophanthus monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  3. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  4. Tyler VE, Brady LR, Robbers JE. Pharmacognosy. 9th ed. Philadelphia, PA: Lea & Febiger, 1988.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Strophanthus and Isavuconazonium Sulfate (IV) Together: Common Questions

Is it safe to take Strophanthus with Isavuconazonium Sulfate (IV)?
We do not list a known interaction between Strophanthus and Isavuconazonium Sulfate (IV). That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Strophanthus and Isavuconazonium Sulfate (IV) have any of the same side effects?
Yes — our sources link each of them separately to 4 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
How was the Strophanthus and Isavuconazonium Sulfate (IV) combination checked?
Interactions in our licensed database are recorded against drug classes. Isavuconazonium Sulfate (IV) is filed under 1 classification, and Strophanthus has documented interactions with 6 drug classes — none of Isavuconazonium Sulfate (IV)'s classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Strophanthus interact with any other medications?
Yes. Strophanthus has 123 documented drug interactions in our database — Isavuconazonium Sulfate (IV) is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Isavuconazonium Sulfate (IV) interact with any supplements?
Yes. Isavuconazonium Sulfate (IV) has documented interactions with 121 supplements in our database — Strophanthus is not one of them. The Isavuconazonium Sulfate (IV) interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Strophanthus monograph Uses, safety profile, and every drug interaction in one place Isavuconazonium drug information The full plain-English guide to this medication Isavuconazonium Sulfate (IV) supplement interactions Every supplement checked against Isavuconazonium Sulfate (IV), ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 4 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Isavuconazonium Sulfate (IV) and Strophanthus?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.