Drug & supplement interaction

Tragacanth + Cabergoline

Cabergoline brand name: Dostinex.

Moderate Interaction
The bottom line Moderate

Tragacanth has a moderate interaction with Cabergoline. Theoretically, tragacanth might alter absorption of oral drugs.

Read the full interaction report
SeverityModerate
LikelihoodPossible
EvidenceD
What do Severity, Likelihood & Evidence mean?
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Interaction report

Tragacanth and Cabergoline

Here is the interaction we found between these two, with the evidence behind it.

Moderate

ORAL DRUGS

Why this applies to Cabergoline

Cabergoline falls under ORAL DRUGS — the group Tragacanth interacts with.

Theoretically, tragacanth might alter absorption of oral drugs.
Tragacanth contains hydrocolloidal fiber which can decrease, increase, or not affect oral drug absorption. To avoid changes in absorption, take tragacanth 30-60 minutes after oral medications.
Severity Moderate Likelihood Possible Evidence D

Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.

Dr. Brian Staiger, PharmD, BCPS
Dr. Brian Staiger explains PharmD, Clinical Pharmacist

Here's the simple version: tragacanth is mostly a gummy fiber that swells into a slippery gel in your stomach. When you swallow it close to a pill like cabergoline, that gel can grab onto the medicine and change how much your body actually absorbs. It might lower the amount that gets in, raise it, or do nothing at all. This is a theoretical concern based on how the gum behaves, not something proven in studies, so I wouldn't lose sleep over it.

Why it matters: cabergoline is taken in tiny doses, usually once or twice a week, so even small absorption shifts could change how well it lowers prolactin, or nudge side effects like nausea, dizziness, or headache. An easy fix is spacing them out, take your cabergoline first and wait 30 to 60 minutes before any tragacanth. When in doubt, run it by your pharmacist.

References
  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.

What These Ratings Mean

Every interaction above is graded three ways — here’s the key to each label.

Severity how clinically significant the interaction is
Major

Clinically significant. Avoid the combination, or use only under close professional supervision.

Moderate

Usually worth avoiding or managing — may need monitoring, a dose change, or timing apart.

Minor

Generally not serious. Be aware of it and mention it to your pharmacist.

Likelihood how strong the evidence is that the interaction actually happens in people
  • LikelyWell-controlled human studies have demonstrated the likely existence of this interaction.
  • ProbableInteraction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.
  • UnlikelyInteraction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Evidence the quality of the studies behind the rating (graded A–D)
  • AHigh-quality meta-analysis (quantitative systematic review).
  • BCase-control study.
  • CConsensus.
  • DAnecdotal evidence.

These ratings are for information only. Never start, stop, or otherwise change your therapy before speaking with your provider.

Keep it in perspective

Tragacanth Also Interacts With Other Medications

Tragacanth has 2,021 moderate known drug interactions in our database — the Cabergoline one above is one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Tragacanth

Covers the 2,830 medications we’ve checked against Tragacanth. Pick one to open its full report.

Everything else you take

See Every Supplement That Interacts With Cabergoline

This page covers Tragacanth only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Cabergoline page lists 17 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).

By severity: 1 major · 7 moderate · 9 minor.

From our pharmacist’s overview on the Cabergoline page

“Cabergoline (Dostinex) works at unusually small doses, often a fraction of a milligram once or twice a week, so anything that keeps part of a tablet from being absorbed can quietly undo prolactin control. That is what the 17 supplements on this list do, and it deserves careful handling.”

Reviewed by 2 · Jul 18, 2026

Open the Cabergoline interaction page

One more smart check

Taking Tragacanth as Part of a Dietary Supplement Product? Check It for Interactions

We hold 34 real supplement products containing Tragacanth, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Tragacanth. Your product may carry other ingredients that interact with Cabergoline too, on top of Tragacanth — and those would not show on this page. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Tragacanth and Cabergoline Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Tragacanth
Top half

#392 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Cabergoline
Top half

#710 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Supplement

About Tragacanth

What is Tragacanth?

Tragacanth
  • Soothing sore throat and cough
  • Digestive upset and constipation
  • Thickening or binding agent in products
  • Skin soothing in creams and pastes

Tragacanth is a plant gum used mainly as a thickener and emulsifier in foods, cosmetics, and medicines, and traditionally to soothe the throat and gut. There is very little solid human research showing it treats any specific condition. It is generally considered safe in food amounts, but anyone with allergies or who is pregnant or breastfeeding should check with a pharmacist or doctor first.

Read the full Tragacanth monograph & all interactions
Medication

About Cabergoline

What Is Cabergoline Used For?

Brand name: Dostinex

Cabergoline tablets are used in adults to treat hyperprolactinemic disorders — conditions where the body produces too much prolactin, a hormone made by the pituitary gland. This excess prolactin can cause irregular periods, unwanted breast milk production, and fertility problems.

The cause may be idiopathic (no clear reason found) or due to a pituitary adenoma (a noncancerous tumor on the pituitary gland). Cabergoline is not approved to stop breast milk production after childbirth, and should not be used for that purpose.

See full Cabergoline drug information
Keep checking

Other Drugs & Tragacanth

Browse every other medication we’ve checked against Tragacanth — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
2,021Moderate
0Minor
808No known interaction
Moderate

2,021 interactions

Showing 60 of 2,021 moderate interactions — see all 2,021 on the Tragacanth page.

No interaction 808 drugs checked — show the list

We also checked Tragacanth against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 808 medications checked with no known interaction — see the full Tragacanth list.

Sources

Sources & How We Checked

Interaction details are evidence-graded and sourced from the Natural Medicines database. The medication overview comes from MedlinePlus.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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Pharmacist Counseling Corner

Taking Tragacanth and Cabergoline Together: Common Questions

Can you take Tragacanth with Cabergoline?
There is a moderate interaction, so it may be acceptable with monitoring or timing changes — but check with your pharmacist first. Read the full details on this page and confirm with your pharmacist before combining them.
How serious is the Tragacanth and Cabergoline interaction?
We rate it Moderate. This combination may require monitoring, a dose adjustment, or separating the times you take each one. Consult your pharmacist before using them together.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Cabergoline and Tragacanth?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.