Drug & supplement interaction

Yarrow + Pramlintide

Pramlintide brand name: Symlin.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Yarrow and Pramlintide in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Yarrow and Pramlintide

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Pramlintide and Yarrow in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Yarrow safety at a glance

Yarrow overall Use caution Often used short-term, but human safety data are limited and allergic reactions can occur.
Pregnancy Likely Unsafe When used orally; yarrow is believed to be an abortifacient and affect the menstrual cycle. Read the full pregnancy detail
Breastfeeding Avoid Not enough safety information, so it is best avoided while breastfeeding.

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Pramlintide and Yarrow? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Pramlintide

Interactions in our licensed database are recorded against drug classes, not just single drug names. Pramlintide is filed under a single classification — antidiabetes drugs. Yarrow has documented interactions with 1 drug class — the most serious being lithium (moderate) — and none of Pramlintide’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Yarrow Does Interact With Other Medications

Yarrow has 1 moderate known drug interaction in our database — Pramlintide isn’t one of them. If you take anything else, check it against the full list below.

Moderate 1 No known interaction 2,829 (incl. Pramlintide)
Taking anything else?

Check Another of Your Medications Against Yarrow

Covers the 2,830 medications we’ve checked against Yarrow. Pick one to open its full report.

What to actually watch for

What Yarrow Itself Has Been Linked To

This is not an interaction — nothing below involves Pramlintide. It is the side-effect record for Yarrow on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Yarrow, this list is the first place to look. 2 entries are worth acting on rather than waiting out — marked below.

  • Wheezing Worth acting on Additional detail

    “Topically, yarrow can cause atopic or allergic dermatitis or urticaria due to its sesquiterpene lactone content. It has also been reported to cause phototoxic and photo-allergic dermatitis and airborne contact dermatitis. In one 44-year-old female, handling yarrow flowers resulted in rhinitis and asthma.”

    Yarrow · Natural Medicines adverse-effect record, reported in asthma.

    4 sources cited
    1. 52558. Uter, W., Nohle, M., Randerath, B., and Schwanitz, H. J. Occupational contact urticaria and late-phase bronchial asthma caused by compositae pollen in a florist. Am J Contact Dermat. 2001;12(3):182-184. DOI
    2. 68385. Schempp, C. M., Schopf, E., and Simon, J. C. [Plant-induced toxic and allergic dermatitis (phytodermatitis)]. Hautarzt 2002;53(2):93-97.
    3. 77007. Jovanovic, M., Poljacki, M., Duran, V., Vujanovic, L., Sente, R., and Stojanovic, S. Contact allergy to Compositae plants in patients with atopic dermatitis. Med Pregl. 2004;57(5-6):209-218. PubMed
    4. 96911. Becker LC, Bergfeld WF, Belsito DV, et al. Safety assessment of Achillea millefolium as used in cosmetics. Int J Toxicol. 2016;35(3 suppl):5S-15S.
  • Hives Worth acting on Additional detail

    “Topically, yarrow can cause atopic or allergic dermatitis or urticaria due to its sesquiterpene lactone content. Yarrow has also been reported to cause phototoxic and photo-allergic dermatitis and airborne contact dermatitis.

    Intravaginally, aggravated facial acne was reported by 1 of 40 patients in a clinical trial.”

    Yarrow · Natural Medicines adverse-effect record, reported in acne.

    4 sources cited
    1. 52558. Uter, W., Nohle, M., Randerath, B., and Schwanitz, H. J. Occupational contact urticaria and late-phase bronchial asthma caused by compositae pollen in a florist. Am J Contact Dermat. 2001;12(3):182-184. DOI
    2. 68385. Schempp, C. M., Schopf, E., and Simon, J. C. [Plant-induced toxic and allergic dermatitis (phytodermatitis)]. Hautarzt 2002;53(2):93-97.
    3. 77007. Jovanovic, M., Poljacki, M., Duran, V., Vujanovic, L., Sente, R., and Stojanovic, S. Contact allergy to Compositae plants in patients with atopic dermatitis. Med Pregl. 2004;57(5-6):209-218. PubMed
    4. 105360. Zakeri S, Esmaeilzadeh S, Gorji N, Memariani Z, Moeini R, Bijani A. The effect of Achillea millefolium L. on vulvovaginal candidiasis compared with clotrimazole: A randomized controlled trial. Complement Ther Med. 2020;52:102483. PubMed
  • Acne Additional detail

    Recorded for Yarrow in the same Natural Medicines adverse-effect record shown under Hives above.

  • A stuffy or runny nose Additional detail

    Recorded for Yarrow in the same Natural Medicines adverse-effect record shown under Wheezing above.

  • Itching Additional detail

    “Intravaginally, aggravated vaginal pruritus and dryness were reported by 1 of 40 patients in a clinical trial.”

    Yarrow · Natural Medicines adverse-effect record, reported in pruritus.

    1 source cited
    1. 105360. Zakeri S, Esmaeilzadeh S, Gorji N, Memariani Z, Moeini R, Bijani A. The effect of Achillea millefolium L. on vulvovaginal candidiasis compared with clotrimazole: A randomized controlled trial. Complement Ther Med. 2020;52:102483. PubMed
  • A skin rash Additional detail

    “Orally and intravaginally, yarrow seems to be well tolerated.

    Most Common Adverse Effects:

    Topically: Dermatitis.”

    Yarrow · Natural Medicines adverse-effect record, reported in dermatitis.

Everything above comes from the Natural Medicines adverse-effect record for Yarrow — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Pramlintide’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Pramlintide column appears here.

Special populations

Yarrow in Pregnancy & Breastfeeding

Pregnancy Likely Unsafe

When used orally; yarrow is believed to be an abortifacient and affect the menstrual cycle.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Pramlintide

This page covers Yarrow only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Pramlintide page lists 239 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Siberian Cocklebur (major), Acai (moderate), African Wild Potato (moderate), Agaricus Mushroom (moderate) and Agmatine (moderate).

By severity: 1 major · 208 moderate · 30 minor.

From our pharmacist’s overview on the Pramlintide page

“The single entry rated major on the pramlintide (Symlin) list is Siberian cocklebur, which has caused severe hypoglycemia in humans, not just in lab studies. That matters more than usual here because pramlintide is injected at mealtimes alongside insulin, and a dangerous low is already the main hazard of that pairing.”

Reviewed by 2 · Jul 18, 2026

Open the Pramlintide interaction page

One more smart check

Taking Yarrow as Part of a Dietary Supplement Product? Check It for Interactions

We hold 600 real supplement products containing Yarrow, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Yarrow. Even though Yarrow itself has no known interaction with Pramlintide, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Yarrow and Pramlintide Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Yarrow
Top 25%

#281 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Pramlintide
Top half

#1,220 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Yarrow reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Yarrow and Pramlintide records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Yarrow

What is Yarrow?

Yarrow
  • Wounds and minor bleeding
  • Digestive upset and cramping
  • Colds, flu, and fever
  • Skin conditions
  • Menstrual discomfort

Yarrow is a traditional herb long used for wounds, digestive complaints, and colds, but high-quality human studies are very limited, so its benefits are not well proven. It is generally used short-term, and people who are pregnant, breastfeeding, or allergic to ragweed and related plants should avoid it.

Achillea millefolium · Asteraceae · Aerial parts (leaves, flowers, and stems) and essential oil · Tea, tincture, capsules, dried herb, topical creams or ointments, and essential oil

An interaction check asks whether these two react with each other — it does not ask whether Yarrow is a good idea for someone in your situation. Here is what our Yarrow record says about it on its own.

Yarrow: dosing

There is no official, standardized dose for yarrow. Traditional use includes teas made from the dried herb, tinctures, and capsules, as well as creams applied to the skin.Because product strengths vary widely, the safest approach is to follow the directions on the product label and not exceed them. Yarrow is intended for short-term use, not long-term daily use.

From our Yarrow monograph — the full record covers uses, side effects and every documented interaction.

Read the full Yarrow monograph & all interactions
Medication

About Pramlintide Injection

What Is Pramlintide Injection Used For?

Brand name: Symlin

SymlinPen (pramlintide) is used as an add-on treatment for adults with type 1 or type 2 diabetes who already use mealtime insulin but still haven't reached their target blood sugar levels — even with optimal insulin therapy.

It is not a replacement for insulin. It works alongside insulin, given right before major meals, to reduce the spike in blood sugar that happens after eating.

See full Pramlintide Injection drug information
Keep checking

Other Drugs & Yarrow

Browse every other medication we’ve checked against Yarrow — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
1Moderate
0Minor
2,828No known interaction
1 Moderate 2,828 No interaction
Moderate

1 interaction

No interaction 2,828 drugs checked — show the list

We also checked Yarrow against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,828 medications checked with no known interaction — see the full Yarrow list.

See the full Yarrow interactions page
See every supplement checked against Pramlintide, ranked by severity
Evidence & sources

Yarrow References

The 8 references that drive our Yarrow monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Uter, W., Nohle, M., Randerath, B., and Schwanitz, H. J. Occupational contact urticaria and late-phase bronchial asthma caused by compositae pollen in a florist. Am J Contact Dermat. 2001;12(3):182-184. DOI
  3. Schempp, C. M., Schopf, E., and Simon, J. C. [Plant-induced toxic and allergic dermatitis (phytodermatitis)]. Hautarzt 2002;53(2):93-97.
  4. Jovanovic, M., Poljacki, M., Duran, V., Vujanovic, L., Sente, R., and Stojanovic, S. Contact allergy to Compositae plants in patients with atopic dermatitis. Med Pregl. 2004;57(5-6):209-218. PubMed
  5. Becker LC, Bergfeld WF, Belsito DV, et al. Safety assessment of Achillea millefolium as used in cosmetics. Int J Toxicol. 2016;35(3 suppl):5S-15S.
  6. Zakeri S, Esmaeilzadeh S, Gorji N, Memariani Z, Moeini R, Bijani A. The effect of Achillea millefolium L. on vulvovaginal candidiasis compared with clotrimazole: A randomized controlled trial. Complement Ther Med. 2020;52:102483. PubMed
  7. de Souza P, Crestani S, da Silva Rde C, et al. Involvement of bradykinin and prostaglandins in the diuretic effects of Achillea millefolium L. (Asteraceae). J Ethnopharmacol. 2013 Aug 26;149(1):157-61. PubMed
  8. Miranzadeh S, Adib-Hajbaghery M, Soleymanpoor L, Ehsani M. Effect of adding the herb Achillea millefolium on mouthwash on chemotherapy induced oral mucositis in cancer patients: A double-blind randomized controlled trial. Eur J Oncol Nurs. 2015;19(3):207- PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Yarrow and Pramlintide Together: Common Questions

Is it safe to take Yarrow with Pramlintide?
We do not list a known interaction between Yarrow and Pramlintide. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Yarrow and Pramlintide combination checked?
Interactions in our licensed database are recorded against drug classes. Pramlintide is filed under 1 classification, and Yarrow has documented interactions with 1 drug class — none of Pramlintide's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Yarrow interact with any other medications?
Yes. Yarrow has 1 documented drug interaction in our database — Pramlintide is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Pramlintide interact with any supplements?
Yes. Pramlintide has documented interactions with 239 supplements in our database — Yarrow is not one of them. The Pramlintide interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Yarrow monograph Uses, safety profile, and every drug interaction in one place Pramlintide Injection drug information The full plain-English guide to this medication Pramlintide supplement interactions Every supplement checked against Pramlintide, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 8 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Pramlintide and Yarrow?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.