Medication interaction hub

What Supplements Interact with Interferon Alfacon-1?

Interferon Alfacon-1 brand name: Infergen. Every interaction below applies to the brands too.

57 Interactions 3 Major 53 Moderate 1 Minor
Curated & coded by · Clinical Pharmacist · Updated September 29, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Interferon Alfacon-1? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Interferon Alfacon-1 against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line
Our Pharmacist Explains
What is this? The interaction data in the HelloPharmacist supplement database is licensed from Natural Medicines Pro by TRC Healthcare (Therapeutic Research). HelloPharmacist pharmacists often add our own analysis and context on top of that licensed data — such as this Bottom Line summary and the notes on individual interaction pages — and any such commentary is noted as ours.

Interferon alfacon-1 (Infergen) treats chronic hepatitis C, a disease of the liver itself, which is exactly why this interaction list deserves real care. Two thirds of the entries, 38 ingredients in all, carry some potential to injure the liver, and adding that strain to an organ already fighting hepatitis is the risk to understand first. Siberian cocklebur has the strongest evidence, including documented cases of liver failure, and regular beer or wine sits alongside it among the most serious entries.

The other cluster is about sun sensitivity. Twenty ingredients, bergamot oil and alfalfa among them, can make skin react more strongly to light, an effect that can stack with the medication's own. Those are moderate concerns rather than emergencies. Of the 57 entries here, only three rate major, all of them liver risks, with 53 moderate and a single minor.

— , Clinical Pharmacist · July 18, 2026

Major 3 Moderate 53 Minor 1 No known interaction 1,395

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Top Ingredient Interactions

Interferon Alfacon-1: Top Interactions at a Glance

The most significant Interferon Alfacon-1 supplement & herbal interactions, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 57 interacting ingredients — plus 1,395 more checked with no known interaction. See the complete ranked list.

Start here

The Major Interactions to Know About

The most clinically significant Interferon Alfacon-1 + supplement combinations in our database, best-documented first. Open any card for the full report.

Major Likelihood Likely Siberian Cocklebur + Interferon Alfacon-1i

Siberian cocklebur can adversely affect the liver.

Read the full interaction Major Likelihood Probable Beer + Interferon Alfacon-1i

Concomitant use of alcohol with hepatotoxic drugs may increase the risk of hepatotoxicity.

Read the full interaction Major Likelihood Probable Wine + Interferon Alfacon-1i

Concomitant use of alcohol with hepatotoxic drugs may increase the risk of hepatotoxicity.

Read the full interaction
The complete list

Every Supplement Checked Against Interferon Alfacon-1

All 1,452 ingredients in our database, ranked by severity — 57 with a Interferon Alfacon-1 interaction on file and 1,395 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Interferon Alfacon-1?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Green Tea with Interferon Alfacon-1?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use might have additive adverse hepatotoxic effects.

Full Green Tea + Interferon Alfacon-1 answer

Can you take Sweet Clover with Interferon Alfacon-1?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of sweet clover with hepatoxic drugs might increase the risk of hepatotoxicity.

Full Sweet Clover + Interferon Alfacon-1 answer

Can you take Manchurian Thorn with Interferon Alfacon-1?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Animal research suggests that high doses of Manchurian thorn can induce liver damage.

Full Manchurian Thorn + Interferon Alfacon-1 answer

Can you take Niacin with Interferon Alfacon-1?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of niacin and hepatotoxic drugs might increase the risk of hepatotoxicity.

Full Niacin + Interferon Alfacon-1 answer

Can you take Noni with Interferon Alfacon-1?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.

Full Noni + Interferon Alfacon-1 answer

Can you take Ostarine with Interferon Alfacon-1?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use with hepatotoxic drugs might increase the risk of adverse hepatotoxic effects.

Full Ostarine + Interferon Alfacon-1 answer

Can you take Padang Cassia with Interferon Alfacon-1?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. There is some concern that ingesting large amounts of Padang cassia might cause hepatotoxicity in some people.

Full Padang Cassia + Interferon Alfacon-1 answer

Can you take Red Yeast Rice with Interferon Alfacon-1?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use might increase the risk of liver damage.

Full Red Yeast Rice + Interferon Alfacon-1 answer

Can you take Rhubarb with Interferon Alfacon-1?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of rhubarb with potentially hepatotoxic drugs might increase the risk of developing liver damage.

Full Rhubarb + Interferon Alfacon-1 answer

Can you take Rue with Interferon Alfacon-1?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, rue might increase the risk for phototoxicity when used with photosensitizing drugs.

Full Rue + Interferon Alfacon-1 answer

Can you take Saigon Cinnamon with Interferon Alfacon-1?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, Saigon cinnamon might cause additive effects when used with hepatotoxic drugs.

Full Saigon Cinnamon + Interferon Alfacon-1 answer

Can you take Spearmint with Interferon Alfacon-1?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, high doses of spearmint might increase the risk of liver damage when taken with hepatotoxic drugs.

Full Spearmint + Interferon Alfacon-1 answer

Can you take St. John's Wort with Interferon Alfacon-1?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, St.

Full St. John's Wort + Interferon Alfacon-1 answer

Can you take Sweet Annie with Interferon Alfacon-1?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use might have additive adverse hepatotoxic effects.

Full Sweet Annie + Interferon Alfacon-1 answer

Can you take Syrian Rue with Interferon Alfacon-1?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, high doses of Syrian rue might increase the risk of liver damage when taken with hepatotoxic drugs.

Full Syrian Rue + Interferon Alfacon-1 answer

Can you take Testolone with Interferon Alfacon-1?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use might have additive hepatotoxic effects.

Full Testolone + Interferon Alfacon-1 answer

Can you take Turmeric with Interferon Alfacon-1?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, turmeric might increase the risk of liver damage when taken with hepatotoxic drugs.

Full Turmeric + Interferon Alfacon-1 answer

Can you take Vitamin A with Interferon Alfacon-1?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking high doses of vitamin A in combination with other potentially hepatotoxic drugs might increase the risk of liver disea...

Full Vitamin A + Interferon Alfacon-1 answer

Can you take Celery with Interferon Alfacon-1?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, celery might increase the risk of photosensitivity reactions when taken with photosensitizing drugs.

Full Celery + Interferon Alfacon-1 answer

Can you take Siberian Cocklebur with Interferon Alfacon-1?

Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. Siberian cocklebur can adversely affect the liver.

Full Siberian Cocklebur + Interferon Alfacon-1 answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Interferon Alfacon-1 is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Interferon Alfacon-1, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Interferon Alfacon-1 sits in 2 interaction categories. Open any one to see what the group means:

Hepatotoxic Drugs 38 ingredients

Medications with known liver considerations. Supplements that can stress the liver add to the load.

38 of the supplement ingredients on this page reach Interferon Alfacon-1 through this category.

Photosensitizing Drugs 20 ingredients

Medications that make skin more sun-sensitive. Supplements with the same property can compound it.

20 of the supplement ingredients on this page reach Interferon Alfacon-1 through this category.

Check a real product

Take a Supplement Product? Check the Whole Bottle Against Interferon Alfacon-1

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Interferon Alfacon-1.

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Pharmacist Counseling Corner

Interferon Alfacon-1 & Supplements: Common Questions

What supplements interact with Interferon Alfacon-1?
Our database currently documents 57 ingredients with a known Interferon Alfacon-1 interaction (3 major, 53 moderate, 1 minor). The practical move: scan the major group first, then look up the exact supplements you take rather than reading all 57. The highest-ranked right now: Siberian Cocklebur, Beer, Wine.
Which Interferon Alfacon-1 supplement interactions are the most serious?
Focus on the major group: Siberian Cocklebur, Beer and Wine. A major rating means the combination can be clinically significant, not that harm is guaranteed — but it's exactly the kind of thing to run past your pharmacist before your next dose, not after. Jump to the ranked list.
Can I take vitamins or supplements while on Interferon Alfacon-1?
Plenty of supplements coexist fine with Interferon Alfacon-1; a shorter list does not. Rather than memorizing it, check the specific ingredients on your labels — the ranked list above covers every one we've checked, and multi-ingredient products can be checked label-by-label with our scanner. Try the label scanner or the interaction checker.
Do brands like Infergen have the same supplement interactions as Interferon Alfacon-1?
Yes — Infergen all contain Interferon Alfacon-1, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
What about Interferon Alfacon-1 and my other medications?
This page covers Interferon Alfacon-1 against supplements and herbal ingredients. Checking Interferon Alfacon-1 against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 29, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.