Medication interaction hub

What Supplements Interact with Tazarotene?

Tazarotene brand names: Avage, Tazorotene, Zorac, Fabior, Arazlo. Every interaction below applies to the brands too.

24 Interactions 1 Major 21 Moderate 2 Minor
Curated & coded by · Clinical Pharmacist · Updated September 23, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Tazarotene? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Tazarotene against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line
Our Pharmacist Explains
What is this? The interaction data in the HelloPharmacist supplement database is licensed from Natural Medicines Pro by TRC Healthcare (Therapeutic Research). HelloPharmacist pharmacists often add our own analysis and context on top of that licensed data — such as this Bottom Line summary and the notes on individual interaction pages — and any such commentary is noted as ours.

Tazarotene (Fabior, Arazlo) is a topical retinoid, a vitamin A relative prescribed for acne and psoriasis, and its supplement list deserves genuine attention. The one major-rated entry is vitamin A itself. Because tazarotene is a vitamin A derivative, adding supplements could stack the two toward toxic levels. Most of the rest, 20 of the 24 ingredients on file, share a single theme, added sun sensitivity. Tazarotene already makes skin burn more easily, and herbs like bergamot, rue, and chlorophyll can push that further.

Three more entries matter because they change how skin absorbs medicine. DMSO in particular can drive topical drugs deeper and amplify both their effects and their side effects. Light therapy is also flagged, since deliberate light exposure pairs badly with a photosensitizing drug. With one major, 21 moderate, and two minor entries here, settle the vitamin A question first, then let the rest push you toward stricter sunscreen and shade habits.

— , Clinical Pharmacist · July 18, 2026

Major 1 Moderate 21 Minor 2 No known interaction 1,428

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Top Ingredient Interactions

Tazarotene: Top Interactions at a Glance

The most significant Tazarotene supplement & herbal interactions, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 24 interacting ingredients — plus 1,428 more checked with no known interaction. See the complete ranked list.

Start here

The Major Interactions to Know About

The most clinically significant Tazarotene + supplement combinations in our database, best-documented first. Open any card for the full report.

Major Likelihood Probable Vitamin A + Tazarotenei

Concomitant use of retinoids with vitamin A supplements might produce supratherapeutic vitamin A levels.

Read the full interaction
The complete list

Every Supplement Checked Against Tazarotene

All 1,452 ingredients in our database, ranked by severity — 24 with a Tazarotene interaction on file and 1,428 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Tazarotene?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Vitamin A with Tazarotene?

Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. Concomitant use of retinoids with vitamin A supplements might produce supratherapeutic vitamin A levels.

Full Vitamin A + Tazarotene answer

Can you take Alchemilla with Tazarotene?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. While no side effects have been reported from orally using Alchemilla, a clinical study titled "Treatment of Aphthous Stomatitis with Topica...

Full Alchemilla + Tazarotene answer

Can you take Celery with Tazarotene?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, celery might increase the risk of photosensitivity reactions when taken with photosensitizing drugs.

Full Celery + Tazarotene answer

Can you take Bergamot with Tazarotene?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, topical bergamot essential oil might increase the risk of side effects when used along with photosensitizing drugs.

Full Bergamot + Tazarotene answer

Can you take Chenopodium Oil with Tazarotene?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of chenopodium oil with other photosensitizing drugs can increase the risk of adverse effects.

Full Chenopodium Oil + Tazarotene answer

Can you take Chlorophyll with Tazarotene?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of chlorophyll with photosensitizing drugs may have additive effects.

Full Chlorophyll + Tazarotene answer

Can you take Chlorophyllin with Tazarotene?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of chlorophyllin with photosensitizing drugs may have additive effects.

Full Chlorophyllin + Tazarotene answer

Can you take Masterwort with Tazarotene?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. The use of masterwort in conjunction with photosensitizing drugs is contraindicated due to the potential for additive photosensitizing effec...

Full Masterwort + Tazarotene answer

Can you take Wild Carrot with Tazarotene?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use might result in increased photosensitivity.

Full Wild Carrot + Tazarotene answer

Can you take Alfalfa with Tazarotene?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of alfalfa with photosensitizing drugs might have additive effects.

Full Alfalfa + Tazarotene answer

Can you take Angelica Archangelica with Tazarotene?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Angelica archangelica, whether ingested or applied to the skin, has the potential to induce photosensitivity reactions.

Full Angelica Archangelica + Tazarotene answer

Can you take Arrach with Tazarotene?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of arrach can increase risk of adverse effects, as unspecified Chenopodium species are associated with photos...

Full Arrach + Tazarotene answer

Can you take Bishop's Weed with Tazarotene?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Bishop's weed constituents seem to cause photosensitivity.

Full Bishop's Weed + Tazarotene answer

Can you take Chlorella with Tazarotene?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, chlorella might have additive effects with photosensitizing drugs.

Full Chlorella + Tazarotene answer

Can you take Cilantro with Tazarotene?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Evidence from in vitro research suggests that coriandrin, a constituent of cilantro, has photosensitizing effects.

Full Cilantro + Tazarotene answer

Can you take Coriander with Tazarotene?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, coriander might increase the risk of photosensitivity when taken with photosensitizing drugs.

Full Coriander + Tazarotene answer

Can you take Dimethylsulfoxide (dmso) with Tazarotene?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Topical DMSO might increase the effects and adverse effects of topical drugs.

Full Dimethylsulfoxide (dmso) + Tazarotene answer

Can you take Fig with Tazarotene?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, fig might increase the risk of photosensitivity when used in combination with photosensitizing drugs.

Full Fig + Tazarotene answer

Can you take Khella with Tazarotene?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use might result in increased photosensitivity.

Full Khella + Tazarotene answer

Can you take Light Therapy with Tazarotene?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Light therapy may increase the risk for photosensitization.

Full Light Therapy + Tazarotene answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Tazarotene is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Tazarotene, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Tazarotene sits in 3 interaction categories. Open any one to see what the group means:

Photosensitizing Drugs 20 ingredients

Medications that make skin more sun-sensitive. Supplements with the same property can compound it.

20 of the supplement ingredients on this page reach Tazarotene through this category.

Topical Drugs 3 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

3 of the supplement ingredients on this page reach Tazarotene through this category.

Retinoids 1 ingredient

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

1 of the supplement ingredient on this page reaches Tazarotene through this category.

About Tazarotene

Tazarotene is a topical retinoid used to reduce the appearance of fine facial wrinkles, uneven skin tone, and age spots, and to treat acne and plaque psoriasis.

Generic name: Tazarotene  ·  Brand names: Avage, Tazorotene, Zorac, Fabior, Arazlo.

See the full Tazarotene Topical drug information

Related: does Tazarotene deplete any nutrients?

Tazarotene has 5 reported nutrient associations in the research literature — see the Tazarotene nutrient depletion report.

Check a real product

Take a Supplement Product? Check the Whole Bottle Against Tazarotene

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Tazarotene.

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Pharmacist Counseling Corner

Tazarotene & Supplements: Common Questions

What supplements interact with Tazarotene?
More than you might expect — 24 in total, though they are far from equal: 1 are rated major, 21 moderate, and 2 minor. The ranked list on this page puts the ones that genuinely matter first, and every entry opens a full report on that exact pair. The highest-ranked right now: Vitamin A, Bergamot, Chenopodium Oil.
Which Tazarotene supplement interactions are the most serious?
The 1 major-rated combination — led by Vitamin A — deserve real caution: these are the ones generally best avoided, or used only with your prescriber watching. If you take any of them today, don't panic and don't stop anything abruptly — call your pharmacist first. Jump to the ranked list.
Can I take vitamins or supplements while on Tazarotene?
Usually yes — most people on Tazarotene can take most supplements. The catch is the exceptions, and they aren't always the exotic ones (St. John's Wort trips up more prescriptions than almost anything sold next to it). Look up each ingredient you actually take in the list above, and treat "no known interaction" as a green-ish light, not a guarantee. Try the label scanner or the interaction checker.
Do brands like Avage have the same supplement interactions as Tazarotene?
Yes — Avage, Tazorotene, Zorac, Fabior, Arazlo all contain Tazarotene, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
Does Tazarotene deplete any vitamins or nutrients?
It might — Tazarotene has 5 reported nutrient-depletion associations in the research literature, which is a different question from interactions: instead of a supplement changing the drug, the drug may lower a nutrient over time. See the Tazarotene nutrient depletion report for the specifics and what to discuss with your pharmacist.
What about Tazarotene and my other medications?
This page covers Tazarotene against supplements and herbal ingredients. Checking Tazarotene against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker, or read the full Tazarotene Topical drug information.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 23, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.