Medication interaction hub

What Supplements Interact with Diclofenac epolamine?

Diclofenac epolamine brand names: Flector, Licart. Every interaction below applies to the brands too.

292 Interactions 6 Major 259 Moderate 27 Minor
Curated & coded by · Clinical Pharmacist · Updated September 24, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Diclofenac epolamine? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Diclofenac epolamine against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line
Our Pharmacist Explains
What is this? The interaction data in the HelloPharmacist supplement database is licensed from Natural Medicines Pro by TRC Healthcare (Therapeutic Research). HelloPharmacist pharmacists often add our own analysis and context on top of that licensed data — such as this Bottom Line summary and the notes on individual interaction pages — and any such commentary is noted as ours.

Even as a patch, diclofenac epolamine (Flector, Licart) is still an NSAID that reaches the bloodstream, and its 292 supplement interactions call for genuine care, six of them rated major. The bulk of the list, 202 ingredients, thins the blood or slows clotting, which stacks onto an NSAID's built-in bleeding risk. Two of those six majors are simply beer and wine, because alcohol with any NSAID raises the odds of stomach bleeding.

Beyond bleeding, a few herbs, Siberian cocklebur among them, can strain kidneys that NSAIDs already tax, and 38 entries add stress to the liver. Twenty photosensitizing ingredients matter more with a medicine worn on the skin, and quercetin raised diclofenac blood levels by 75 percent in one small study. The remaining 259 moderate and 27 minor entries are workable once you know which group a supplement belongs to, but the six majors are where to start reading.

— , Clinical Pharmacist · July 18, 2026

Major 6 Moderate 259 Minor 27 No known interaction 1,160

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Most Viewed Ingredient Interactions

Diclofenac epolamine: Top Interactions at a Glance

The Diclofenac epolamine supplement & herbal interactions people checked most in the last 24 hours, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 292 interacting ingredients — plus 1,160 more checked with no known interaction. See the complete ranked list.

Start here

The Most-Checked Diclofenac epolamine Combinations Today

The Diclofenac epolamine + supplement pages people viewed most in the last 24 hours (resets at midnight). Open any card for the full report.

Moderate Likelihood Possible Grape + Diclofenac epolaminei

Theoretically, grape extracts may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.

Read the full interaction Minor Likelihood Unlikely Cranberry + Diclofenac epolaminei

Theoretically, cranberry might increase the levels and adverse effects of CYP2C9 substrates.

Read the full interaction Moderate Likelihood Possible Chaga + Diclofenac epolaminei

Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.

Read the full interaction Major Likelihood Probable Beer + Diclofenac epolaminei

Concomitant use may increase the risk of gastrointestinal (GI) bleeding.

Read the full interaction Moderate Likelihood Possible Evening Primrose + Diclofenac epolaminei

Theoretically, evening primrose oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.

Read the full interaction Minor Likelihood Unlikely Fish Oil + Diclofenac epolaminei

Fish oil may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.

Read the full interaction
The complete list

Every Supplement Checked Against Diclofenac epolamine

All 1,452 ingredients in our database, ranked by severity — 292 with a Diclofenac epolamine interaction on file and 1,160 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Diclofenac epolamine?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Grape with Diclofenac epolamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, grape extracts may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet...

Full Grape + Diclofenac epolamine answer

Can you take Cranberry with Diclofenac epolamine?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, cranberry might increase the levels and adverse effects of CYP2C9 substrates.

Full Cranberry + Diclofenac epolamine answer

Can you take Chaga with Diclofenac epolamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.

Full Chaga + Diclofenac epolamine answer

Can you take Beer with Diclofenac epolamine?

Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. Concomitant use may increase the risk of gastrointestinal (GI) bleeding.

Full Beer + Diclofenac epolamine answer

Can you take Evening Primrose with Diclofenac epolamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, evening primrose oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.

Full Evening Primrose + Diclofenac epolamine answer

Can you take Panax Ginseng with Diclofenac epolamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Although Panax ginseng has shown antiplatelet effects in the laboratory, it is unlikely to increase the risk of bleeding if used with antico...

Full Panax Ginseng + Diclofenac epolamine answer

Can you take Sweet Woodruff with Diclofenac epolamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use might increase the effects of some anticoagulant and antiplatelet drugs and increase the risk of bleeding.

Full Sweet Woodruff + Diclofenac epolamine answer

Can you take Alchemilla with Diclofenac epolamine?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. While no side effects have been reported from orally using Alchemilla, a clinical study titled "Treatment of Aphthous Stomatitis with Topica...

Full Alchemilla + Diclofenac epolamine answer

Can you take Chromium with Diclofenac epolamine?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. NSAIDs might increase chromium levels in the body.

Full Chromium + Diclofenac epolamine answer

Can you take Fever Bark with Diclofenac epolamine?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, combining fever bark with antiplatelet or anticoagulant drugs might have additive effects; however, this has not been reporte...

Full Fever Bark + Diclofenac epolamine answer

Can you take Fucus Vesiculosus with Diclofenac epolamine?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, concomitant use of Fucus vesiculosus with CYP2C9 substrates might increase the risk for adverse effects.

Full Fucus Vesiculosus + Diclofenac epolamine answer

Can you take Genistein Combined Polysaccharide with Diclofenac epolamine?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Some evidence suggests that genistein can alter the pharmacokinetics of CYP2C9 substrates and should be used cautiously with them.

Full Genistein Combined Polysaccharide + Diclofenac epolamine answer

Can you take Hemp with Diclofenac epolamine?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.

Full Hemp + Diclofenac epolamine answer

Can you take Rabdosia Rubescens with Diclofenac epolamine?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. In vitro research shows that oridonin, a constituent of Rabdosia rubescens, induces cytochrome P450 2C9 (CYP2C9) enzyme.

Full Rabdosia Rubescens + Diclofenac epolamine answer

Can you take Rauvolfia Vomitoria with Diclofenac epolamine?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, combining Rauvolfia vomitoria with antiplatelet or anticoagulant drugs might have additive effects.

Full Rauvolfia Vomitoria + Diclofenac epolamine answer

Can you take Turkey Tail Mushroom with Diclofenac epolamine?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, the polysaccharide peptide (PSP) component of turkey tail mushroom might inhibit CYP2C9.

Full Turkey Tail Mushroom + Diclofenac epolamine answer

Can you take Yohimbe with Diclofenac epolamine?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, combining yohimbe bark with antiplatelet or anticoagulant drugs might have additive effects; however, this has not been repor...

Full Yohimbe + Diclofenac epolamine answer

Can you take Algal Oil with Diclofenac epolamine?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, algal oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.

Full Algal Oil + Diclofenac epolamine answer

Can you take Asian Water Plantain with Diclofenac epolamine?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Studies on animals have shown that Asian water plantain extract, which contains triterpenoids, is generally safe at doses up to 1440 mg/kg o...

Full Asian Water Plantain + Diclofenac epolamine answer

Can you take Fish Oil with Diclofenac epolamine?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Fish oil may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.

Full Fish Oil + Diclofenac epolamine answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Diclofenac epolamine is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Diclofenac epolamine, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Diclofenac epolamine sits in 10 interaction categories. Open any one to see what the group means:

Anticoagulant/Antiplatelet Drugs 202 ingredients

Blood-thinning medications. Supplements with their own effects on clotting or platelets can add up with these drugs and raise bleeding risk.

202 of the supplement ingredients on this page reach Diclofenac epolamine through this category.

Cytochrome P450 2C9 (Cyp2C9) Substrates 64 ingredients

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

64 of the supplement ingredients on this page reach Diclofenac epolamine through this category.

Hepatotoxic Drugs 38 ingredients

Medications with known liver considerations. Supplements that can stress the liver add to the load.

38 of the supplement ingredients on this page reach Diclofenac epolamine through this category.

Photosensitizing Drugs 20 ingredients

Medications that make skin more sun-sensitive. Supplements with the same property can compound it.

20 of the supplement ingredients on this page reach Diclofenac epolamine through this category.

Diclofenac (Voltaren, Others) 6 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

6 of the supplement ingredients on this page reach Diclofenac epolamine through this category.

Nephrotoxic Drugs 6 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

6 of the supplement ingredients on this page reach Diclofenac epolamine through this category.

Nonsteroidal Anti-Inflammatory Drugs (Nsaids) 5 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

5 of the supplement ingredients on this page reach Diclofenac epolamine through this category.

Organic Anion Transporter 1 (Oat1) Substrates 4 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

4 of the supplement ingredients on this page reach Diclofenac epolamine through this category.

Organic Anion Transporter 3 (Oat3) Substrates 4 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

4 of the supplement ingredients on this page reach Diclofenac epolamine through this category.

Topical Drugs 3 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

3 of the supplement ingredients on this page reach Diclofenac epolamine through this category.

Related: does Diclofenac epolamine deplete any nutrients?

Diclofenac epolamine has 2 reported nutrient associations in the research literature — see the Diclofenac epolamine nutrient depletion report.

Check a real product

Take a Supplement Product? Check the Whole Bottle Against Diclofenac epolamine

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Diclofenac epolamine.

Search a supplement product

Type a product name, brand, or UPC — smart search across our full catalog.

Grounded search over our product catalog — every verdict comes from our interaction database, never AI guesswork. How we use AI

Or scan the bottle

Photograph any Supplement Facts panel — we read the ingredients and check each one against your medications. Free, in seconds.

Open the label scanner

Prefer typing? The interaction checker looks up products by name too.

Pharmacist Counseling Corner

Diclofenac epolamine & Supplements: Common Questions

What supplements interact with Diclofenac epolamine?
More than you might expect — 292 in total, though they are far from equal: 6 are rated major, 259 moderate, and 27 minor. The ranked list on this page puts the ones that genuinely matter first, and every entry opens a full report on that exact pair. The highest-ranked right now: Siberian Cocklebur, Beer, Danshen.
Which Diclofenac epolamine supplement interactions are the most serious?
Focus on the major group: Siberian Cocklebur, Beer, Danshen, Piracetam and Wine, among others. A major rating means the combination can be clinically significant, not that harm is guaranteed — but it's exactly the kind of thing to run past your pharmacist before your next dose, not after. Jump to the ranked list.
Can I take vitamins or supplements while on Diclofenac epolamine?
Usually yes — most people on Diclofenac epolamine can take most supplements. The catch is the exceptions, and they aren't always the exotic ones (St. John's Wort trips up more prescriptions than almost anything sold next to it). Look up each ingredient you actually take in the list above, and treat "no known interaction" as a green-ish light, not a guarantee. Try the label scanner or the interaction checker.
Do brands like Flector have the same supplement interactions as Diclofenac epolamine?
Yes — Flector, Licart all contain Diclofenac epolamine, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
Does Diclofenac epolamine deplete any vitamins or nutrients?
It might — Diclofenac epolamine has 2 reported nutrient-depletion associations in the research literature, which is a different question from interactions: instead of a supplement changing the drug, the drug may lower a nutrient over time. See the Diclofenac epolamine nutrient depletion report for the specifics and what to discuss with your pharmacist.
What about Diclofenac epolamine and my other medications?
This page covers Diclofenac epolamine against supplements and herbal ingredients. Checking Diclofenac epolamine against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

More Free Pharmacist Tools

Supplement interaction checker Check any supplement or product against your medications Supplement label scanner Photograph a Supplement Facts panel; we check every ingredient Browse medications A–Z Every drug we’ve checked against herbs & supplements Ingredient directory Every vitamin, herb & mineral we track, with interaction data Product directory Look up any bottle by name, brand, or barcode Ask a pharmacist Free, personal answer from our licensed team
Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 24, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.