Interactions on record — worth a quick check against your medications. Based on 5 of 7 ingredients. Check your meds →
Dietary supplement

Advanced Probiotics 15 Billion Berry Flavor Ingredients & Drug Interactions

by Life Nutrition

Advanced Probiotics 15 Billion Berry Flavor label
See full label image
Tablet Or Pill Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Advanced Probiotics 15 Billion Berry Flavor against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Advanced Probiotics 15 Billion Berry Flavor is a dietary supplement by Life Nutrition with 7 active ingredients. Its ingredients are commonly taken for constipation, diarrhea, high cholesterol.Based on those ingredients, 2,121 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Dietary Fiber, Sodium, Probiotic Blend. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Advanced Probiotics 15 Billion Berry Flavor by Life Nutrition

Ask about any prescription or over-the-counter medication and we check it for interactions with Advanced Probiotics 15 Billion Berry Flavor by Life Nutrition — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Advanced Probiotics 15 Billion Berry Flavor by Life Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 3 of its 11 active ingredients.
  • “Probiotic Blend” is a proprietary blend — the label doesn't break down how much of each component you get.
  • “Nutrition Facts Per Serving” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.

This formula has 11 ingredients, including 11 active probiotic and prebiotic components. The probiotic strains are Lactobacillus rhamnosus GG, Lactobacillus acidophilus LA14, Bifidobacterium lactis BL04, Lactobacillus plantarum LP115, Lactobacillus salivarius LS33, Lactobacillus paracasei LPC37, Lactobacillus casei LC11, and Bifidobacterium longum BL05—together delivering 15 billion live organisms.

Inulin is included as a prebiotic (food for the beneficial bacteria), and sodium is a mineral that's essential in small amounts but present here as well. The tablet also contains inactive ingredients like xylitol, microcrystalline cellulose, stearic acid, hydroxypropyl cellulose, magnesium stearate, citric acid, silica, and natural flavors for the berry taste.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: supports healthy digestion and immune system.
  • We looked for evidence on: Antibiotic-associated diarrhea, Bacterial vaginosis, Celiac disease, Clostridioides difficile infection, Common cold, Constipation — and 4 related terms.
  • The strongest evidence on file: Black Psyllium is rated "Effective" for Constipation (Natural Medicines).
  • Also on file: Sodium is rated "Likely Effective" for Cystic fibrosis.
  • Also on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Antibiotic-associated diarrhea, Bacterial vaginosis, Helicobacter pylori.

Evidence for these probiotics is mixed depending on the specific strain and condition. Lactobacillus acidophilus appears possibly effective for irritable bowel syndrome, Helicobacter pylori infection, antibiotic-associated diarrhea, and bacterial vaginosis.

Inulin is possibly effective for obesity, constipation, and diabetes. However, we don't have established evidence for Bifidobacterium longum or most of the other strains in this blend for any particular condition—the data simply isn't there yet.

If you're taking this for a specific health concern, it's worth asking your pharmacist whether the evidence supports its use for your situation.

The evidence, ingredient by ingredient Black Psyllium Sodium Lactobacillus Acidophilus Bifidobacterium Longum Inulin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 5 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 5 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

These probiotics are generally well tolerated in healthy adults and children. The most common side effects are mild gastrointestinal—bloating, gas, abdominal discomfort, or changes in bowel habits—and they're uncommon.

There is a theoretical concern that live probiotic organisms could, in very rare cases, cause infection in people who are seriously ill or have severely weakened immune systems; most documented cases have occurred in premature infants or critically ill patients. Sodium in this product is fine at normal dietary amounts, but if you take sodium supplements or have high blood pressure or heart disease, you should avoid extra sodium.

For pregnancy and lactation, Lactobacillus acidophilus is rated possibly safe during pregnancy, but data on lactation are limited; Bifidobacterium longum and inulin are both rated possibly safe in pregnancy and lactation.

Side effects, ingredient by ingredient Black Psyllium Sodium Lactobacillus Acidophilus Bifidobacterium Longum Inulin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 5 of the 5 matched ingredients can interact with medications — Black Psyllium, Lactobacillus Acidophilus, Inulin, Sodium, Bifidobacterium Longum.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications; heart-rhythm medications; lithium.
  • For scale: 2,122 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this, check with your pharmacist if you're on blood pressure medications, corticosteroids, lithium, didanosine, diabetes drugs, antibiotics, or any other sodium-containing medication. The sodium in this formula and the live probiotics both have documented interactions.

Time your antibiotic doses and probiotics several hours apart if you can.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product may be worth trying if you're interested in probiotics for digestive support or one of the conditions where evidence is stronger (like antibiotic-associated diarrhea). However, if you take blood pressure medications, lithium, diabetes drugs, or any antibiotic, or if you have heart disease or high blood pressure, you'll need to check with your pharmacist first—especially about timing if you're on antibiotics.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 11 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Advanced Probiotics 15 Billion Berry Flavor, straight from the product label.

Brand Life Nutrition
Net contents 30 Chewable Tablet(s); 0.66 Oz(s); 18.6 Gram(s)
Market status On market
Date entered into DSLD Aug 23, 2019
DSLD ID 206165
Product type Other Combinations
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Advanced Probiotics 15 Billion Berry Flavor by Life Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
Servings per container
30
IngredientAmount% DV
Sugar0.1 Gram(s)--
Dietary Fiber0.1 Gram(s)--
Saturated Fat0.1 Gram(s)--
Sodium1 mg--
Trans Fat0 Gram(s)--
Total Fat0.1 Gram(s)--
Carbohydrates0.5 Gram(s)--
Added Sugars0 Gram(s)--
Energy0 NP--
Lactobacillus rhamnosus GG0 NP--
Protein0.1 Gram(s)--
Probiotic Blend0 NP--
Lactobacillus acidophilus LA140 NP--
Bifidobacterium lactis BL040 NP--
Lactobacillus plantarum LP1150 NP--
Lactobacillus salivarius LS330 NP--
Lactobacillus paracasei LPC370 NP--
Lactobacillus casei LC110 NP--
Bifidobacterium longum BL050 NP--
Inulin10 mg--
Nutrition Facts Per Serving0 NP--

Other ingredients: Xylitol, Microcrystalline Cellulose, Stearic Acid, Beet, Hydroxypropyl Cellulose, Natural flavor, Magnesium Stearate, Citric Acid, Silica, Ingredients, Sweetener, Probiotic Blend, Anti-Caking Agent, Natural flavors, Color, Thickener, Inulin, Citric Acid

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Happy Digestion and Healthy Immune System Formulated with 8 widely studied probiotic strains, including Lactobacillus rhamnosus GG, Life Nutrition Advanced Probiotics helps populate your intestinal tract with friendly bacteria to support your digestive health and overall wellness. Promotes Immune Support Keeps you healthy with the No. 1 most studied probiotic strain, Lactobacillus rhamnosus GG, which supports your natural immune system.

With Lactobacillus rhamnosus GG, the No. 1 Most Studied Probiotic

8 widely studied probiotic strains including Lactobacillus rhamnosus GG

General Statements

Supports healthy digestion Balancing bellies is essential for happy digestion. Each chewable tablet delivers 15 billion CFU active cultures from a blend of eight widely researched strains. Two-step packaging process to minimize heat and light in order to prolong probiotics' shelf life. Step 1 Flush packaging environment with nitrogen to remove oxygen and moisture Step 2 Use cold foil to individually seal each tablet for optimal protection Double foil protection

Guaranteed Potency through date on box

Contains prebiotics for probiotics to multiply & survive

15 Billion Active Cultures Guaranteed

Restores natural balance of friendly bacteria in your digestive tract Regulates bowel movements

Traveler-friendly Packaging

Manufactured in USA

Formulation

Sugar, Dairy & Gluten Free

Sugar free

Storage

Refrigeration not required

Store in a cool, dry place away from direct sunlight. Do not exceed 24(0)C (75(0)F). Refrigeration is not required.

Guaranteed potency through date on box when stored according to instructions above.

Suggested/Recommended/Usage/Directions

One-a-Day

Directions Chew 1 tablet daily. Continued daily use is suggested.

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Advanced Probiotics 15 Billion Berry Flavor by Life Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Advanced Probiotics 15 Billion Berry Flavor label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Advanced Probiotics 15 Billion Berry Flavor by Life Nutrition

These are the 7 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Dietary Fiber

Interacts with
2,025 drugs
0.1 Gram(s) per serving

Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. I...

Dietary Fiber monograph & interactions

Sodium

Interacts with
205 drugs
1 mg per serving

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets g...

Sodium monograph & interactions

Carbohydrates

0.5 Gram(s) per serving
  • › Sugar

Probiotic Blend

Interacts with
182 drugs
0 NP per serving

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy p...

Probiotic Blend monograph & interactions

Inulin

Interacts with
86 drugs
10 mg per serving Form: Chicory

Inulin is a type of plant fiber (a prebiotic) found naturally in foods like chicory root, onions, and garlic, and it is widely added to supplements an...

Inulin monograph & interactions

Nutrition Facts Per Serving

0 NP per serving
  • › Energy
  • › Protein

Other (inactive) ingredients: Xylitol, Microcrystalline Cellulose, Stearic Acid, Beet, Hydroxypropyl Cellulose, Natural flavor, Magnesium Stearate, Citric Acid, Silica, Ingredients, Sweetener, Probiotic Blend, Anti-Caking Agent, Natural flavors, Color, Thickener, Inulin, Citric Acid. These complete the product’s ingredient list but are not active constituents.

Interaction report

Advanced Probiotics 15 Billion Berry Flavor by Life Nutrition Drug Interactions

Want to check YOUR meds against Advanced Probiotics 15 Billion Berry Flavor?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2,121Drugs
409 Moderate 1,712 Minor

Ingredients driving the most interactions

Dietary Fiber 2,025
Sodium 205
Probiotic Blend 182
Inulin 86

Individual Drug Interactions

The ingredients in Advanced Probiotics 15 Billion Berry Flavor interact with 2,121 drugs. Click any drug to see the details.

4 of the 7 ingredients in Advanced Probiotics 15 Billion Berry Flavor interact with drugs. Each result below shows which ingredient is responsible. Dietary Fiber Sodium Probiotic Blend Inulin

Each ingredient & the kinds of drugs it affects

For each ingredient in Advanced Probiotics 15 Billion Berry Flavor with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Dietary Fiber7 drug types · 2,025 drugs

Carbamazepine (Tegretol)

Theoretically, black psyllium might reduce the effects of carbamazepine and increase the risk for convulsions.
Theoretically, black psyllium might reduce carbamazepine absorption. A preliminary study using blond psyllium reported decreased carbamazepine bioavailability due to binding of the drug to psyllium, as well as reduction of available fluid in the gut for dissolution of the drug. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Lithium

Theoretically, taking black psyllium at the same time as lithium might reduce lithium absorption.
The fiber in black psyllium might reduce lithium absorption and plasma levels. Some case reports describe a reduction in plasma lithium levels with concomitant administration of blond psyllium. This was reversed when psyllium was stopped. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Metformin (Glucophage)

Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Animal research shows that concurrent consumption of blond psyllium with metformin slows and increases the absorption of metformin. This interaction may also occur with black psyllium. To avoid changes in absorption, take psyllium 30-60 minutes after metformin.

Likelihood Possible Evidence D
Olanzapine (Zyprexa)

Theoretically, taking black psyllium at the same time as olanzapine might reduce olanzapine absorption.
The fiber in black psyllium might decrease the absorption of olanzapine. A single case report describes a reduction in the effectiveness of olanzapine when it was concomitantly administered with an unspecified type of psyllium 3 grams orally twice daily. This effect was reversed when psyllium was stopped.

Likelihood Possible Evidence D
Digoxin (Lanoxin)

Theoretically, taking black psyllium at the same time as digoxin might reduce digoxin absorption and decrease digoxin levels.
Psyllium might bind digoxin in the gut. However, some clinical evidence suggests that psyllium does not impact digoxin absorption.

Likelihood Unlikely Evidence B
Ethinyl Estradiol

Theoretically, taking black psyllium at the same time as ethinyl estradiol might alter levels of estradiol.
Concurrent use of blond psyllium with ethinyl estradiol results in a slight increase in the extent of ethinyl estradiol absorption and a slower rate of absorption. This is unlikely to be clinically significant.

Likelihood Unlikely Evidence D
Oral Drugs

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Psyllium seems to have variable effects on drug absorption. To avoid changes in absorption, take psyllium 30-60 minutes after oral medications. Animal research shows that blond psyllium delays and increases the absorption of metformin and ethinyl estradiol. Case reports and animal research suggest that blond psyllium might reduce absorption of lithium, digoxin, olanzapine, and carbamazepine. Finally, some pharmacokinetic studies show that psyllium does not affect the absorption of levothyroxine or warfarin. Although many of these studies evaluated blond psyllium, the fiber content in black psyllium may have similar effects.

Likelihood Possible Evidence B
Dietary Fiber full monograph & interactions

Sodium7 drug types · 205 drugs

Antihypertensive Drugs

Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
High intake of dietary sodium can increase systolic and diastolic blood pressure. Also, high intake of sodium may necessitate increased use of antihypertensive medications to achieve blood pressure control in some patients, such as those with chronic kidney disease.

Likelihood Probable Evidence A
Corticosteroids

Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Mineralocorticoids and some glucocorticoids (corticosteroids) cause sodium retention. This effect is dose-related and depends on mineralocorticoid potency. It is most common with hydrocortisone, cortisone, and fludrocortisone, followed by prednisone and prednisolone.

Likelihood Possible Evidence D
Didanosine (Videx)

Concomitant use of didanosine with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia.
Didanosine formulations contain a significant amount of sodium.

Likelihood Probable Evidence C
Lithium

Altering dietary intake of sodium might alter the levels and clinical effects of lithium.
High sodium intake can reduce plasma concentrations of lithium by increasing lithium excretion. Reducing sodium intake can significantly increase plasma concentrations of lithium and cause lithium toxicity in patients being treated with lithium carbonate. Stabilizing sodium intake is shown to reduce the percentage of patients with lithium level fluctuations above 0.8 mEq/L. Patients taking lithium should avoid significant alterations in their dietary intake of sodium.

Likelihood Probable Evidence B
Sodium Phosphates

Theoretically, concomitant use of sodium phosphate with sodium supplements might increase the risk of hypernatremia.
Use of high doses (> 45 mL in 24 hours) of sodium phosphate, such as those used for bowel cleansing before surgery, can lead to serious electrolyte disturbances, including hypernatremia. The risk of hypernatremia is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Sodium-Containing Drugs

Concomitant use of sodium-containing drugs with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia and long-term sodium-related complications.
The Chronic Disease Risk Reduction (CDRR) intake level of 2.3 grams of sodium daily indicates the intake at which it is believed that chronic disease risk increases for the apparently healthy population. Some medications contain high quantities of sodium. When used in conjunction with sodium supplements or high-sodium diets, the CDRR may be exceeded. Additionally, concomitant use may increase the risk for hypernatremia; this risk is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Tolvaptan (Samsca)

Theoretically, concomitant use of tolvaptan with sodium might increase the risk of hypernatremia.
Tolvaptan is a vasopressin receptor 2 antagonist that is used to increase sodium levels in patients with hyponatremia. Patients taking tolvaptan should use caution with the use of sodium salts such as sodium chloride.

Likelihood Probable Evidence C
Sodium full monograph & interactions

Probiotic Blend1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.

Likelihood Probable Evidence D
Probiotic Blend full monograph & interactions

Inulin1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, inulin might increase the risk of hypoglycemia with antidiabetes drugs.
Some clinical research shows that inulin improves glycemic control in patients with diabetes; however, it is unclear if it has hypoglycemic effects.

Likelihood Unlikely Evidence D
Inulin full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Advanced Probiotics 15 Billion Berry Flavor, from the product label.

Life Nutrition

See all Life Nutrition products
Name
Life Nutrition Group Inc.
Street Address
6402 8th Ave.
City
Brooklyn
State
NY
ZipCode
11220
Web Address
LifeNutrition.com
Pharmacist Counseling Corner

Advanced Probiotics 15 Billion Berry Flavor by Life Nutrition: Common Questions

Does Advanced Probiotics 15 Billion Berry Flavor by Life Nutrition interact with any medications?
Yes. Based on its ingredients, Advanced Probiotics 15 Billion Berry Flavor has a known interaction with 2,121 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Advanced Probiotics 15 Billion Berry Flavor contains 7 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while I'm on antibiotics?
You can, but timing matters. The antibiotic might kill off the live probiotic organisms if you take them at the same time, so try to space them out—ask your pharmacist for the best timing. Once you finish your antibiotics, the probiotics become more useful again.
Will this help my irritable bowel syndrome?
Lactobacillus acidophilus in this formula is possibly effective for IBS. That means there's some evidence it may help, but it's not proven. It's worth a try, but talk to your doctor about whether it makes sense for your specific situation.
What's inulin and why is it in there?
Inulin is a type of fiber that acts as a prebiotic—food for the good bacteria in this formula. It's possibly effective for constipation, obesity, and blood sugar control. However, it often causes gas and bloating, especially when you first start taking it, so start with a lower dose and increase slowly.
Is this safe to take while pregnant or breastfeeding?
The probiotics in this formula are rated possibly safe during pregnancy and lactation based on the data we hold. However, safety data are limited for some ingredients, so talk with your doctor or midwife before starting any supplement during pregnancy or while nursing.
What side effects should I watch for?
Most people experience little or nothing. Some notice mild bloating, gas, or temporary changes in bowel habits—these usually settle down as your body adjusts. Serious side effects are very rare and are mainly a concern only in people who are critically ill or have severely weakened immune systems.
Is there a lot of sodium in this?
The product does contain sodium, and if you have high blood pressure, take blood pressure medication, or have heart disease, that's something to discuss with your pharmacist. Normal dietary sodium is fine, but you shouldn't add extra sodium supplements without checking first.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Advanced Probiotics 15 Billion Berry Flavor is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Advanced Probiotics 15 Billion Berry Flavor label
Go deeper

The Full Monographs Behind Advanced Probiotics 15 Billion Berry Flavor’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Black Psyllium

Interacts with 2,025 drugs

Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. It is best known and most studied for rel...

Read the full Black Psyllium monograph → Herb & supplement monograph

Sodium

Interacts with 205 drugs

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets get more than enough—often too much—from...

Read the full Sodium monograph → Herb & supplement monograph

Lactobacillus Acidophilus

Interacts with 182 drugs

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...

Read the full Lactobacillus Acidophilus monograph → Herb & supplement monograph

Bifidobacterium Longum

Interacts with 182 drugs

Bifidobacterium longum is a 'friendly' bacterium found naturally in the human gut and used as a probiotic. It is generally well tolerated and is most studied for digestive issues, though evi...

Read the full Bifidobacterium Longum monograph → Herb & supplement monograph

Inulin

Interacts with 86 drugs

Inulin is a type of plant fiber (a prebiotic) found naturally in foods like chicory root, onions, and garlic, and it is widely added to supplements and processed foods. It may help with regu...

Read the full Inulin monograph →
Sources

Sources & How We Checked

Advanced Probiotics 15 Billion Berry Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 109 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Black Psyllium 18 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  3. Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
  4. Etman M. Effect of a bulk forming laxative on the bioavailablility of carbamazepine in man. Drug Dev Ind Pharm 1995;21:1901-6.
  5. Perlman BB. Interaction between lithium salts and ispaghula husk. Lancet 1990;335:416.
  6. Vaswani SK, Hamilton RG, Valentine MD, Adkinson NF. Psyllium laxative-induced anaphylaxis, asthma, and rhinitis. Allergy 1996;51:266-8. PubMed
  7. Lantner RR, Espiritu BR, Zumerchik P, Tobin MC. Anaphylaxis following ingestion of a psyllium-containing cereal. JAMA 1990;264:2534-6. DOI
  8. Kaplan MJ. Anaphylactic reaction to "Heartwise." N Engl J Med 1990;323:1072-3. DOI
  9. Nordstrom M, Melander A, Robertsson E, Steen B. Influence of wheat bran and of a bulk-forming ispaghula cathartic on the bioavailability of digoxin in geriatric in-patients. Drug Nutr Interact 1987;5:67-9..
  10. Robinson DS, Benjamin DM, McCormack JJ. Interaction of warfarin and nonsystemic gastrointestinal drugs. Clin Pharmacol Ther 1971;12:491-5. PubMed
  11. Garcia JJ, Fernandez N, Diez MJ, et al. Influence of two dietary fibers in the oral bioavailability and other pharmacokinetic parameters of ethinyloestradiol. Contraception 2000;62:253-7. PubMed
  12. Fernandez N, Lopez C, Díez R, et al. Drug interactions with the dietary fiber Plantago ovata husk. Expert Opin Drug Metab Toxicol 2012;8(11):1377-86.
  13. Semen plantaginis in: WHO Monographs on Selected Medicinal Plants, volume 1. World Health Organization, Geneva, 1999. Available at http://apps.who.int/medicinedocs/en/d/Js2200e/. Accessed November 26, 1026.
  14. Code of Federal Regulations, Title 21 (21CFR 101.17). Food labeling warning, notice, and safe handling statements. Available at www.ecfr.gov/cgi-bin/text-idx?SID=20f647d3b74161501f46564b915b4048&mc=true&node=se21.2.101_117&rgn=div8. Accessed December 3, 2
  15. Code of Federal Regulations, Title 21 (21CFR 201.319). Specific labeling requirements - water-soluble gums, hydrophilic gums, and hydrophilic mucilloids. Available at www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=201.319. Accessed Dece
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Sodium 38 references
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See these in context on the Sodium monograph →

Lactobacillus Acidophilus 15 references
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See these in context on the Lactobacillus Acidophilus monograph →

Bifidobacterium Longum 21 references
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  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed
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See these in context on the Bifidobacterium Longum monograph →

Inulin 17 references
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  11. Smiljanec K, Mitchell CM, Privitera OF, Neilson AP, Davy KP, Davy BM. Pre-meal inulin consumption does not affect acute energy intake in overweight and obese middle-aged and older adults: A randomized controlled crossover pilot trial. Nutr Health. 2017;23 PubMed
  12. Cai X, Yu H, Liu L, et al. Milk powder co-supplemented with inulin and resistant dextrin improves glycemic control and insulin resistance in elderly type 2 diabetes mellitus: a 12-week randomized, double-blind, placebo-controlled trial. Mol Nutr Food Res PubMed
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  14. Mitchell CM, Davy BM, Ponder MA, et al. Prebiotic Inulin Supplementation and Peripheral Insulin Sensitivity in adults at Elevated Risk for Type 2 Diabetes: A Pilot Randomized Controlled Trial. Nutrients 2021;13(9):3235. PubMed
  15. Li L, Li P, Xu L. Assessing the effects of inulin-type fructan intake on body weight, blood glucose, and lipid profile: A systematic review and meta-analysis of randomized controlled trials. Food Sci Nutr 2021;9(8):4598-4616. PubMed
  16. Ziaei R, Shahshahan Z, Ghasemi-Tehrani H, Heidari Z, Ghiasvand R. Effects of inulin-type fructans with different degrees of polymerization on inflammation, oxidative stress and endothelial dysfunction in women with polycystic ovary syndrome: A randomized,
  17. Risso D, Kaczmarczyk M, Laurie I, et al. Moderate intakes of soluble corn fibre or inulin do not cause gastrointestinal discomfort and are well tolerated in healthy children. Int J Food Sci Nutr 2022;73(8):1104-1115. PubMed

See these in context on the Inulin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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