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Dietary supplement

Advanced Total Body + Refresh Ingredients & Drug Interactions

by Schiff MegaRed

Softgel Capsule Category: Botanical With Nutrients
Most serious interaction: Minor
The interaction bottom line Most serious interaction: Minor

Advanced Total Body + Refresh is a dietary supplement by Schiff MegaRed with 5 active ingredients. Its ingredients are commonly taken for minor wounds and skin healing, skin inflammation and irritation, diaper rash.Based on those ingredients, 248 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Marigold Flower Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Computed from our clinical databases

HelloPharmacist Scorecard of Advanced Total Body + Refresh by Schiff MegaRed

Four independent checks of what is known — a summary of the available information, not a grade of the product itself.

Evidence for Intended Use
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

The stated purpose hasn't been mapped to our evidence data yet.

Why this rating?
  • We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Ingredient Transparency
Partial

Most active ingredients list an amount, but at least one is hidden in a blend or missing.

Why this rating?
  • The label discloses an exact amount for 3 of its 5 active ingredients.
  • “EPA and DHA Blend” is a proprietary blend — the label gives one combined amount (350 mg) without saying how much of each component you get.
Known Interaction Concern
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Calendula.
  • The most serious interaction on file is rated Minor.
  • For scale: 248 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Safety Information
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

HelloPharmacist summaryPartially disclosed formula with no assessable stated purpose. Only minor medication interactions are documented, and safety information is well characterized.

Assessment coverage: 1 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 16, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Advanced Total Body + Refresh, straight from the product label.

Brand Schiff MegaRed
Net contents 65 Softgel(s)
Market status On market
Date entered into DSLD Jun 16, 2022
DSLD ID 263801
Product type Botanical With Nutrients
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Advanced Total Body + Refresh by Schiff MegaRed, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
65
IngredientAmount% DV
Total Fat1 Gram(s)1%
Calories10 Calorie(s)--
Docosahexaenoic Acid Ethyl Ester0 NP--
EPA and DHA Blend350 mg--
Eicosapentaenoic Acid Ethyl Ester0 NP--
Proprietary Omega-3 Blend500 mg--
Total Omega-3 Fatty Acids375 mg--
Marigold Flower Extract30 mg--

Other ingredients: Gelatin, Glycerin, Sunflower Oil, Water, Sorbitol Solution, natural Vanilla, mixed Tocopherols, Caramel color, Carmine color, Mica, Titanium Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Contains Fish (Anchovy, Sardine, Mackerel), Shellfish (Krill), and Soy. This product contains sulfites.

Caution: If you are pregnant, breastfeeding, allergic to seafood, have existing medical conditions, taking medications (including blood thinners) or are planning a medical or surgical procedure, consult a healthcare professional before use.

Caution: If you are pregnant, breastfeeding, allergic to seafood, have existing medical conditions, taking medications (including blood thinners) or are planning a medical or surgical procedure, consult a healthcare professional before use.

Keep out of reach of children.

Protected with a tamper evident seal. Do not use if seal under cap is broken or missing.

Brand IP Statement(s)

Copyright 2019 RB Health

General Statements

For information all: 1-800-526-6251

Storage

Store in a cool, dry place with lid tightly closed and protected from light. Do not remove freshness pack from bottle.

Formula

Gelatin is derived from bovine sources.

Lutein and Zeaxanthin

Formulation

Heart Brains Joints Eyes + Sleep Stress Skin

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Adult take one (1) softgel daily.

See for yourself

Advanced Total Body + Refresh by Schiff MegaRed label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Advanced Total Body + Refresh by Schiff MegaRed

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container65 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

EPA and DHA Blend

350 mg per serving Form: Ethyl Esters
  • › Docosahexaenoic Acid Ethyl Ester
  • › Eicosapentaenoic Acid Ethyl Ester

Proprietary Omega-3 Blend

500 mg per serving Form: Fish Oil concentrate, Krill Oil

Total Omega-3 Fatty Acids

375 mg per serving Form: Ethyl Esters

Marigold Flower Extract

Interacts with
248 drugs
30 mg per serving Form: Lutein, Tagetes erecta Flower Extract, Zeaxanthin

Calendula is a flowering plant whose petals are used mainly in skin creams, oils, and ointments to soothe minor irritation and support wound healing....

Marigold Flower Extract monograph & interactions

Other (inactive) ingredients: Gelatin, Glycerin, Sunflower Oil, Water, Sorbitol Solution, Natural Vanilla, Mixed Tocopherols, Caramel color, Carmine color, Mica, Titanium Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Advanced Total Body + Refresh by Schiff MegaRed Drug Interactions

Advanced Total Body + Refresh contains 5 ingredients, and 1 of them has known drug interactions. Altogether it interacts with 248 medications. Here’s the picture, then you can look up your own drug.

Want to check YOUR meds against Advanced Total Body + Refresh?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
248Drugs
248 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Advanced Total Body + Refresh with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Marigold Flower Extract1 drug type · 248 drugs

Cns Depressants

Theoretically, calendula might have additive effects when used with CNS depressants, although this appears to be unlikely.
Although some animal research has suggested that a saponoside constituent in calendula may have sedative effects, calendula has been used for over 30 years without reports of sedation in humans.

Likelihood Unlikely Evidence D
The maker

Brand information

Manufacturer and brand details for Advanced Total Body + Refresh, from the product label.

Schiff MegaRed

See all Schiff MegaRed products
Name
RB Health (US) LLC
City
Parsippany
State
NJ
ZipCode
07054-0224
Phone Number
1-800-526-6251
Web Address
www.megared.com
Pharmacist Counseling Corner

Advanced Total Body + Refresh by Schiff MegaRed: Common Questions

Does Advanced Total Body + Refresh by Schiff MegaRed interact with any medications?
Yes. Based on its ingredients, Advanced Total Body + Refresh has a known interaction with 248 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Advanced Total Body + Refresh contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Advanced Total Body + Refresh is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Advanced Total Body + Refresh label
Go deeper

The Full Monographs Behind Advanced Total Body + Refresh’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Advanced Total Body + Refresh's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 9 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Calendula 9 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Reider N, Komericki P, Hausen BM, et al. The seamy side of natural medicines: contact sensitization to arnica (Arnica montana L.) and marigold (Calendula officinalis L.). Contact Dermatitis 2001;45:269-72..
  3. Gol'dman II. [Anaphylactic shock after gargling with an infusion of Calendula]. Klin Med (Mosk) 1974;52:142-3.
  4. Paulsen E. Contact sensitization from Compositae-containing herbal remedies and cosmetics. Contact Dermatitis 2002;47:189-98. PubMed
  5. Bojadjiev C. On the sedative and hypotensive effect of preparations from the plant Calendula officinalis. Nauch Trud Visshi Med Inst Sof 1964;43:15-20.
  6. Samochowiec L. Pharmacological study of saponosides from Aralia mandshurica Rupr. et Maxim and Calendula officinalis L. Herba Pol. 1983;29:151-155.
  7. Madisetti M, Kelechi TJ, Mueller M, Amella EJ, Prentice MA. Feasibility, acceptability, and tolerability of RGN107 in the palliative wound care management of chronic wound symptoms. J Wound Care. 2017;26(Sup1):S25-S34. PubMed
  8. Final Assessment report on Calendula officinalis L., flos. European Medicines Agency: Committee on Herbal Medicinal Products (HMPC). 2018. EMA/HMPC/603409/2017. Available at: https://www.ema.europa.eu/en/documents/herbal-report/final-assessment-report-cal
  9. Puaratanaarunkon T, Washrawirul C, Chuenboonngarm N, Noppakun N, Asawanonda P, Kumtornrut C. Efficacy and safety of a facial serum containing snail secretion filtrate, Calendula officinalis, and Glycyrrhiza glaba root extract in the treatment of maskne: A

See these in context on the Calendula monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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