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Dietary supplement

Agmatine Nitric Oxide Ingredients & Drug Interactions

by Prime Nutrition Precision Series

Agmatine Nitric Oxide label
See full label image
Powder Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Agmatine Nitric Oxide against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Agmatine Nitric Oxide is a dietary supplement by Prime Nutrition Precision Series with 1 active ingredient. Its ingredients are commonly taken for pre- and post-workout support, muscle pumps and exercise performance, cognitive support and mood.Based on those ingredients, 258 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Agmatine Sulfate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Agmatine Nitric Oxide by Prime Nutrition Precision Series

Ask about any prescription or over-the-counter medication and we check it for interactions with Agmatine Nitric Oxide by Prime Nutrition Precision Series — and tell you which ingredient is responsible.

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Computed from our clinical databases

HelloPharmacist Scorecard of Agmatine Nitric Oxide by Prime Nutrition Precision Series

Four independent checks of what is known — a summary of the available information, not a grade of the product itself.

Evidence for Intended Use
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

The stated purpose hasn't been mapped to our evidence data yet.

Why this rating?
  • We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Ingredient Transparency
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.
Known Interaction Concern
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Agmatine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 258 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Safety Information
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Agmatine Nitric Oxide, straight from the product label.

Brand Prime Nutrition Precision Series
Barcode (UPC) 689466706031
Net contents 1.76 oz.; 50 Gram(s)
Market status Off market
Date entered into DSLD Feb 25, 2015
DSLD ID 42336
Product type Non-nutrient/non-botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Agmatine Nitric Oxide by Prime Nutrition Precision Series, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Gram(s)
Maximum serving Sizes:
1 Gram(s)
Servings per container
50
UPC/BARCODE
689466706031
IngredientAmount% DV
Agmatine Sulfate1 Gram(s)--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

PERFORMANCE TRAINING USAGE: As a dietary supplement consume 1 serving 30 minutes prior to exercise. Mix into 4oz of water or juice. For best results consume an additional scoop intra-workout.

General Statements

-THE BEST OR NOTHING-

AGMATINE SULFATE Agmatine Sulfate can be used to support increased nitric oxide levels in the body for a variety of goals. Agmatine is for users who are aiming to increase vascularity, muscle pumps, enhance endurance and muscle performance.

WWW.PRIMENUTRITION.COM

NITRIC OXIDE ENHANCER* GLUCOSE DISPOSAL* & HGH STIMULATOR*

Formula

100% PURE MICRONIZED AGMATINE SULFATE

50G 50/SERVINGS

Precautions

WARNING: Not for use by individuals under the age of 18 years.

Do not use if you are pregnant or nursing.

Do not exceed recommended serving. Exceeding recommended serving may cause serious adverse health effects. Discontinue use and call a physician or licensed qualified health care professional immediately if you experience any adverse symptoms. Improper use of this product may be hazardous to a person's health. Exceeding recommended serving will not improve results.

FDA Disclaimer Statement

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

{You Tube}

P

{Facebook}

{Instagram}

{Twitter}

Formulation

No Artificial Colors or Dyes

FDA Statement of Identity

DIETARY SUPPLEMENT

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Agmatine Nitric Oxide by Prime Nutrition Precision Series label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Agmatine Nitric Oxide label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Agmatine Nitric Oxide by Prime Nutrition Precision Series

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Gram(s) Dosage formPowder Servings per container50 Amounts shown are per serving.

Agmatine Sulfate

Interacts with
258 drugs
1 Gram(s) per serving

Agmatine is a compound your body makes from the amino acid arginine, and it is sold mainly as a workout and 'pump' supplement. Human evidence for most...

Agmatine Sulfate monograph & interactions
Interaction report

Agmatine Nitric Oxide by Prime Nutrition Precision Series Drug Interactions

Agmatine Nitric Oxide contains a single active ingredient, and it has known interactions with 258 medications. Here’s the picture, then you can look up your own drug.

Want to check YOUR meds against Agmatine Nitric Oxide?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
258Drugs
258 Moderate

Ingredients driving the most interactions

Agmatine Sulfate 258

Individual Drug Interactions

The ingredients in Agmatine Nitric Oxide interact with 258 drugs. Click any drug to see the details.

1 of the 1 ingredient in Agmatine Nitric Oxide interact with drugs. Each result below shows which ingredient is responsible. Agmatine Sulfate

Each ingredient & the kinds of drugs it affects

For each ingredient in Agmatine Nitric Oxide with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Agmatine Sulfate2 drug types · 258 drugs

Antidiabetes Drugs

Theoretically, agmatine might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal and in vitro research suggest that agmatine has mild hypoglycemic effects.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, agmatine might increase the risk of hypotension when taken with antihypertensive drugs.
Animal research suggests that agmatine can modestly decrease heart rate and blood pressure.

Likelihood Possible Evidence D
Agmatine Sulfate full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Agmatine Nitric Oxide, from the product label.

Prime Nutrition Precision Series

See all Prime Nutrition Precision Series products
Name
Prime Nutrition(R) Prime Nutrition LLC
Street Address
21218 St. Andrews Blvd. Suite 230
City
Boca Raton
State
FL
ZipCode
33434
Pharmacist Counseling Corner

Agmatine Nitric Oxide by Prime Nutrition Precision Series: Common Questions

Does Agmatine Nitric Oxide by Prime Nutrition Precision Series interact with any medications?
Yes. Based on its ingredients, Agmatine Nitric Oxide has a known interaction with 258 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Agmatine Nitric Oxide contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Agmatine Nitric Oxide is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Agmatine Nitric Oxide label
Go deeper

The Full Monographs Behind Agmatine Nitric Oxide’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Agmatine

Interacts with 258 drugs

Agmatine is a compound your body makes from the amino acid arginine, and it is sold mainly as a workout and 'pump' supplement. Human evidence for most of its claimed benefits is limited and...

Read the full Agmatine monograph →
Sources

Sources & How We Checked

Agmatine Nitric Oxide's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Agmatine 3 references
  1. Piletz JE, Aricioglu F, Cheng JT, et al. Agmatine: clinical applications after 100 years in translation. Drug Discov Today 2013;18(17-18):880-93. PubMed
  2. Keynan O, Mirovsky Y, Dekel S, Gilad VH, Gilad GM. Safety and efficacy of dietary agmatine sulfate in lumbar disc-associated radiculopathy. An open-label, dose-escalating study followed by a randomized, double-blind, placebo-controlled trial. Pain Med 201 PubMed
  3. Shopsin B. The clinical antidepressant effect of exogenous agmatine is not reversed by parachlorophenylalanine: a pilot study. Acta Neuropsychiatr 2013;25(2):113-8. PubMed

See these in context on the Agmatine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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