Aloe Fuzion Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Aloe Fuzion against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Aloe Fuzion is a dietary supplement by Global Healing Center with 1 active ingredient. Its ingredients are commonly taken for minor burns and skin irritation, wound healing, constipation.Based on those ingredients, 461 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are organic inner leaf Aloe. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Aloe Fuzion by Global Healing Center
Ask about any prescription or over-the-counter medication and we check it for interactions with Aloe Fuzion by Global Healing Center — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
Ask the Pharmacist
A licensed pharmacist will answer your question by email — free, usually within 24 hours.
Got it — thank you!
A licensed pharmacist will answer within 24 hours. Keep an eye on your email (worth checking spam, just in case).
HelloPharmacist Scorecard of Aloe Fuzion by Global Healing Center
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product has one active ingredient: organic inner leaf aloe. Aloe is a gel derived from the inner leaf of the aloe plant; it's different from aloe latex, which is the yellow substance found just under the plant's outer skin and carries stronger laxative effects.
The capsule also contains inactive ingredients—organic gum acacia, a vegetable capsule, and organic rice flour—to hold and deliver the aloe.
Does it work?
Moderate evidence
In our data, aloe is rated possibly effective for acne, obesity, diabetes, psoriasis, burns, and constipation. That means there's preliminary clinical evidence for these uses, but more research is needed to confirm how well it works and in whom.
If you're considering it for one of these conditions, talk with your pharmacist or doctor about whether the evidence supports it for your situation.
How safe is it?
Well-documented data
Aloe gel taken by mouth is generally well tolerated in typical doses. However, aloe latex—the yellow substance under the outer leaf—carries a higher risk of side effects, especially at high doses or with long-term use.
Common oral side effects include abdominal pain, cramps, and diarrhea. Serious but rare effects from long-term overuse include muscle weakness, heart rhythm problems, and severe potassium loss; one documented case involved a patient taking 1 liter daily for two weeks.
During pregnancy, avoid aloe by mouth—it may stimulate the uterus and act as a strong laxative. Also avoid it while breastfeeding due to limited safety data and its laxative effects.
If you are pregnant or nursing, talk with your doctor or pharmacist before considering this product.
Meds to double-check
Major interaction found
Before you take Aloe Fuzion, double-check your medications with your pharmacist. The most important: digoxin (heart medication, Major risk), then blood thinners like warfarin, diabetes drugs, water pills (diuretics), and stimulant laxatives (all Moderate risk).
A Minor interaction also exists with certain drugs your liver processes via the CYP1A2 enzyme.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.
Aloe Fuzion may be worth considering if you're looking at it for constipation, burns, or skin conditions and you don't take heart, blood-thinning, diabetes, or water-pill medications. If you do take any prescription drugs—especially digoxin, warfarin, or diabetes or heart meds—check with your pharmacist or doctor first.
This product is not appropriate during pregnancy or while breastfeeding.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 23, 2020.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Aloe Fuzion, straight from the product label.
| Brand | Global Healing Center |
|---|---|
| Barcode (UPC) | 811839030294 |
| Net contents | 60 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Jul 23, 2020 |
| DSLD ID | 231076 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Organic, Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Aloe Fuzion by Global Healing Center, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| organic inner leaf Aloe | 180 mg | -- |
Other ingredients: organic Gum Acacia, Vegetable Capsule, Nu-Flow organic Rice
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested use: Take one capsule in the morning and one in the evening with purified water.
Formula
Aloe Fuzion contains the most bio-available aloe with the highest amount of Acemannan made today. Acemannan is the main active ingredient for immune support and gut health. Aloe Fuzion is aloin free, so it does not act as a harsh laxative like many whole leaf aloe products.
Bio-Active formula made with organic inner leaf aloe vera
Precautions
Warning: Keep out of reach of children.
Consult your healthcare provider if pregnant, nursing or for any additional concerns.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
General Statements
Global healing Center since 1998
FDA Statement of Identity
All Natural Dietary Supplement
Seals/Symbols
GMO Free Vegan Gluten free No Animal Testing
Formulation
GMO free Gluten free
Vegan
Certified Organic by Natural Food Certifiers.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Aloe Fuzion by Global Healing Center label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Aloe Fuzion by Global Healing Center
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.
Organic inner leaf Aloe
Interacts with461 drugs
Aloe vera gel is widely used on the skin for minor burns and irritation, and some research suggests it may help. Aloe latex (the yellow part) is a str...
Organic inner leaf Aloe monograph & interactionsOther (inactive) ingredients: Organic Gum Acacia, Vegetable Capsule, Nu-Flow organic Rice. These complete the product’s ingredient list but are not active constituents.
Aloe Fuzion by Global Healing Center Drug Interactions
HelloPharmacist Interaction Report
Aloe Fuzion contains organic inner leaf aloe, which does interact with several medication types and warrants a careful medication check before you start.
Read the full breakdown — every affected drug type, severity by severity
The most serious concern is digoxin (Lanoxin), a heart medication. Overuse of aloe latex can deplete potassium, and low potassium combined with digoxin raises the risk of toxicity and dangerous heart effects.
If you take digoxin, do not use this product without talking to your doctor or pharmacist first.
Aloe also interacts with blood thinners and blood clot preventers (anticoagulants and antiplatelets), including warfarin—increasing bleeding risk. It may lower blood sugar, so if you take diabetes medications, you'll need close glucose monitoring.
Aloe can compound potassium loss from water pills (diuretics), and using it alongside stimulant laxatives risks serious fluid and electrolyte loss. It may also affect how your body processes certain drugs metabolized by the liver enzyme CYP1A2.
Altogether, these interactions span 460 individual medications. Use the medication checker on this page to verify your exact prescriptions before you begin.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Aloe Fuzion?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Aloe Fuzion interact with 461 drugs. Click any drug to see the details.
1 of the 1 ingredient in Aloe Fuzion interact with drugs. Each result below shows which ingredient is responsible. organic inner leaf Aloe
DigoxinDigitek, Lanoxicaps, Lanoxin
How Digoxin interacts with Aloe Fuzion — through 1 ingredient. Tap an ingredient for the detail:
Organic Inner Leaf AloeDigoxin (lanoxin) Major
Interaction Summary
Theoretically, aloe latex might increase the risk of adverse effects when taken with cardiac glycosides.
Read the full Organic Inner Leaf Aloe + Digoxin interactionAbciximabReoPro
How Abciximab interacts with Aloe Fuzion — through 1 ingredient. Tap an ingredient for the detail:
Organic Inner Leaf AloeAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Organic Inner Leaf Aloe + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Aloe Fuzion — through 1 ingredient. Tap an ingredient for the detail:
Organic Inner Leaf AloeAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Organic Inner Leaf Aloe + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Aloe Fuzion — through 1 ingredient. Tap an ingredient for the detail:
Organic Inner Leaf AloeAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Organic Inner Leaf Aloe + Acarbose interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Aloe Fuzion — through 1 ingredient. Tap an ingredient for the detail:
Organic Inner Leaf AloeAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Organic Inner Leaf Aloe + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Aloe Fuzion — through 1 ingredient. Tap an ingredient for the detail:
Organic Inner Leaf AloeCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Organic Inner Leaf Aloe + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Aloe Fuzion — through 1 ingredient. Tap an ingredient for the detail:
Organic Inner Leaf AloeAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Organic Inner Leaf Aloe + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Aloe Fuzion — through 1 ingredient. Tap an ingredient for the detail:
Organic Inner Leaf AloeCytochrome P450 1a2 (cyp1a2) Substrates, Diuretic Drugs Moderate
Interaction Summary
Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Organic Inner Leaf Aloe + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Aloe Fuzion — through 1 ingredient. Tap an ingredient for the detail:
Organic Inner Leaf AloeAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Organic Inner Leaf Aloe + Acetaminophen, Ibuprofen interactionAcetaminophen, Pamabrom, PyrilamineMidol Max Strength PMS, Pamprin, Pamprin ES
How Acetaminophen, Pamabrom, Pyrilamine interacts with Aloe Fuzion — through 1 ingredient. Tap an ingredient for the detail:
Organic Inner Leaf AloeCytochrome P450 1a2 (cyp1a2) Substrates, Diuretic Drugs Moderate
Interaction Summary
Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Organic Inner Leaf Aloe + Acetaminophen, Pamabrom, Pyrilamine interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Aloe Fuzion — through 1 ingredient. Tap an ingredient for the detail:
Organic Inner Leaf AloeDiuretic Drugs Moderate
Interaction Summary
Theoretically, aloe latex might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Organic Inner Leaf Aloe + Acetazolamide interactionAcetohexamideDymelor
How Acetohexamide interacts with Aloe Fuzion — through 1 ingredient. Tap an ingredient for the detail:
Organic Inner Leaf AloeAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Organic Inner Leaf Aloe + Acetohexamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Aloe Fuzion — through 1 ingredient. Tap an ingredient for the detail:
Organic Inner Leaf AloeAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Organic Inner Leaf Aloe + Acetylsalicylic Acid interactionAlbiglutideTanzeum
How Albiglutide interacts with Aloe Fuzion — through 1 ingredient. Tap an ingredient for the detail:
Organic Inner Leaf AloeAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Organic Inner Leaf Aloe + Albiglutide interactionAlogliptinNesina
How Alogliptin interacts with Aloe Fuzion — through 1 ingredient. Tap an ingredient for the detail:
Organic Inner Leaf AloeAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Organic Inner Leaf Aloe + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Aloe Fuzion — through 1 ingredient. Tap an ingredient for the detail:
Organic Inner Leaf AloeAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Organic Inner Leaf Aloe + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Aloe Fuzion — through 1 ingredient. Tap an ingredient for the detail:
Organic Inner Leaf AloeAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Organic Inner Leaf Aloe + Alogliptin, Pioglitazone interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with Aloe Fuzion — through 1 ingredient. Tap an ingredient for the detail:
Organic Inner Leaf AloeAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Organic Inner Leaf Aloe + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Aloe Fuzion — through 1 ingredient. Tap an ingredient for the detail:
Organic Inner Leaf AloeAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Organic Inner Leaf Aloe + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Aloe Fuzion — through 1 ingredient. Tap an ingredient for the detail:
Organic Inner Leaf AloeAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Organic Inner Leaf Aloe + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with Aloe Fuzion — through 1 ingredient. Tap an ingredient for the detail:
Organic Inner Leaf AloeDiuretic Drugs Moderate
Interaction Summary
Theoretically, aloe latex might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Organic Inner Leaf Aloe + Amiloride, Hydrochlorothiazide interactionAmmonium ChlorideAmmonium Chloride
How Ammonium Chloride interacts with Aloe Fuzion — through 1 ingredient. Tap an ingredient for the detail:
Organic Inner Leaf AloeDiuretic Drugs Moderate
Interaction Summary
Theoretically, aloe latex might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Organic Inner Leaf Aloe + Ammonium Chloride interactionAnacaulase-bcdbNexoBrid
How Anacaulase-bcdb interacts with Aloe Fuzion — through 1 ingredient. Tap an ingredient for the detail:
Organic Inner Leaf AloeAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Organic Inner Leaf Aloe + Anacaulase-bcdb interactionAnagrelideAgrylin
How Anagrelide interacts with Aloe Fuzion — through 1 ingredient. Tap an ingredient for the detail:
Organic Inner Leaf AloeAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Organic Inner Leaf Aloe + Anagrelide interactionAnisindioneMiradon
How Anisindione interacts with Aloe Fuzion — through 1 ingredient. Tap an ingredient for the detail:
Organic Inner Leaf AloeAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Organic Inner Leaf Aloe + Anisindione interactionAntidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) InhibitorGlyxambi
How Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interacts with Aloe Fuzion — through 1 ingredient. Tap an ingredient for the detail:
Organic Inner Leaf AloeAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Organic Inner Leaf Aloe + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interactionAntithrombin IiiThrombate III
How Antithrombin Iii interacts with Aloe Fuzion — through 1 ingredient. Tap an ingredient for the detail:
Organic Inner Leaf AloeAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Organic Inner Leaf Aloe + Antithrombin Iii interactionApixabanEliquis
How Apixaban interacts with Aloe Fuzion — through 1 ingredient. Tap an ingredient for the detail:
Organic Inner Leaf AloeAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Organic Inner Leaf Aloe + Apixaban interactionArgatrobanArgatroban
How Argatroban interacts with Aloe Fuzion — through 1 ingredient. Tap an ingredient for the detail:
Organic Inner Leaf AloeAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Organic Inner Leaf Aloe + Argatroban interactionArmodafinilNuvigil
How Armodafinil interacts with Aloe Fuzion — through 1 ingredient. Tap an ingredient for the detail:
Organic Inner Leaf AloeStimulant Laxatives Moderate
Interaction Summary
Theoretically, aloe latex might increase the risk for fluid and electrolyte loss when taken with stimulant laxatives.
Read the full Organic Inner Leaf Aloe + Armodafinil interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Aloe Fuzion with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
organic inner leaf Aloe
Digoxin (Lanoxin)
Theoretically, aloe latex might increase the risk of adverse effects when taken with cardiac glycosides.
Overuse of aloe latex can increase the risk of adverse effects from cardiac glycoside drugs, such as digoxin, due to potassium depletion. Overuse of aloe, along with cardiac glycoside drugs, can increase the risk of toxicity.
Anticoagulant/Antiplatelet Drugs
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro research shows that aloe gel can inhibit platelet aggregation. This inhibition was greater than that seen with celecoxib, but less than that seen with aspirin.
Antidiabetes Drugs
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Preliminary clinical research suggests aloe gel might lower blood glucose levels and have additive effects when used with antidiabetes drugs. Monitor blood glucose levels closely.
Diuretic Drugs
Theoretically, aloe latex might increase the risk of hypokalemia when taken with diuretic drugs.
Overuse of aloe latex might compound diuretic-induced potassium loss, increasing the risk of hypokalemia.
Stimulant Laxatives
Theoretically, aloe latex might increase the risk for fluid and electrolyte loss when taken with stimulant laxatives.
Due to cathartic laxative effects of aloe latex, concomitant use with other stimulant laxatives might compound fluid and electrolyte loss.
Warfarin (Coumadin)
Theoretically, aloe latex might increase the risk of bleeding when taken with warfarin.
Aloe latex has stimulant laxative effects. In some people aloe latex can cause diarrhea. Diarrhea can increase the effects of warfarin, increase international normalized ratio (INR), and increase the risk of bleeding. Advise patients who take warfarin not to take excessive amounts of aloe vera.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that aloe extract induces CYP1A2 enzymes.
Brand information
Manufacturer and brand details for Aloe Fuzion, from the product label.
Global Healing Center
See all Global Healing Center products- Name
- Global Healing Center, LP.
- City
- Houston
- State
- Texas
- ZipCode
- 77018
- Phone Number
- 1.800.476.0016
- Web Address
- www.globalhealingcenter.com
Aloe Fuzion by Global Healing Center: Common Questions
Does Aloe Fuzion by Global Healing Center interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will this help my constipation?
Can I take this if I'm pregnant?
What's the difference between aloe gel and aloe latex?
What are the most common side effects?
Can I breastfeed while taking this?
Is this effective for acne or skin conditions?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Aloe Fuzion is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Aloe Fuzion’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Aloe Fuzion's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 41 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Aloe 41 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- Wichtl MW. Herbal Drugs and Phytopharmaceuticals. Ed. N.M. Bisset. Stuttgart: Medpharm GmbH Scientific Publishers, 1994.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Nusko G, Schneider B, Schneider I, et al. Anthranoid laxative use is not a risk factor for colorectal neoplasia: results of a prospective case control study. Gut 2000;46:651-5. PubMed
- Luyckx VA, Ballantine R, Claeys M, et al. Herbal remedy-associated acute renal failure secondary to Cape aloes. Am J Kidney Dis 2002;39:E13. PubMed
- Rajasekaran S, Sivagnanam K, Ravi K, Subramanian S. Hypoglycemic effect of Aloe vera gel on streptozotocin-induced diabetes in experimental rats. J Med Food 2004;7:61-6.
- Williams MS, Burk M, Loprinzi CL, et al. Phase III double-blind evaluation of an aloe vera gel as a prophylactic agent for radiation-induced skin toxicity. Int J Radiat Oncol Biol Phys 1996;36:345-9. PubMed
- Vogler BK, Ernst E. Aloe vera: a systematic review of its clinical effectiveness. Br J Gen Pract 1999;49:823-8.
- Bottenberg MM, Wall GC, Harvey RL, Habib S. Oral aloe vera-induced hepatitis. Ann Pharmacother 2007;41:1740-3. PubMed
- Rabe C, Musch A, Schirmacher P, et al. Acute hepatitis induced by an Aloe vera preparation: a case report. World J Gastroenterol 2005;11:303-4. PubMed
- Kanat O, Ozet A, Ataergin S. Aloe vera-induced acute toxic hepatitis in a healthy young man. Eur J Int Med 2006;17:589. PubMed
- Mueller SO, Stopper H. Characterization of the genotoxicity of anthraquinones in mammalian cells. Biochim Biophys Acta 1999;1428:406-14. PubMed
- Schorkhuber M, Richter M, Dutter A, et al. Effect of anthraquinone laxatives on the proliferation and urokinase secretion of normal, premalignant and malignant colonic epithelial cells. Eur J Cancer 1998;34:1091-8. PubMed
- Yang HN, Kim DJ, Kim YM, et al. Aloe-induced toxic hepatitis. J Korean Med Sci 2010;25:492-5. PubMed
- Choonhakarn C, Busaracome P, Sripanidkulchai B, et al. A prospective, randomized clinical trial comparing topical aloe vera with 0.1% triamcinolone acetonide in mild to moderate plaque psoriasis. J.Eur.Acad.Dermatol.Venereol. 2010;24:168-72. PubMed
- Ishii Y, Tanizawa H, Takino Y. Studies of aloe. IV. Mechanism of cathartic effect. (3). Biol Pharm Bull. 1994;17:495-7. PubMed
- Ishii Y, Tanizawa H, Takino Y. Studies of aloe. V. Mechanism of cathartic effect. (4). Biol Pharm Bull. 1994;17:651-3. PubMed
- Nelemans FA. Clinical and toxicological aspects of anthraquinone laxatives. Pharmacology. 1976;14 Suppl 1:73-7. PubMed
- Paulsen E, Korsholm L, Brandrup F. A double-blind, placebo-controlled study of a commercial Aloe vera gel in the treatment of slight to moderate psoriasis vulgaris. J Eur Acad Dermatol Venereol. 2005;19:326-31.
- Huseini HF, Kianbakht S, Hajiaghaee R, et al. Anti-hyperglycemic and anti-hypercholesterolemic effects of Aloe vera leaf gel in hyperlipidemic type 2 diabetic patients: a randomized double-blind placebo-controlled clinical trial. Planta Med. 2012;78:311-6
- Ferreira, M., Teixeira, M., Silva, E., and Selores, M. Allergic contact dermatitis to Aloe vera. Contact Dermatitis 2007;57(4):278-279.
- Choonhakarn, C., Busaracome, P., Sripanidkulchai, B., and Sarakarn, P. The efficacy of aloe vera gel in the treatment of oral lichen planus: a randomized controlled trial. Br J Dermatol 2008;158(3):573-577. PubMed
- Baretta, Z., Ghiotto, C., Marino, D., and Jirillo, A. Aloe-induced hypokalemia in a patient with breast cancer during chemotherapy. Ann.Oncol. 2009;20(8):1445-1446. PubMed
- Hunter, D. and Frumkin, A. Adverse reactions to vitamin E and aloe vera preparations after dermabrasion and chemical peel. Cutis 1991;47(3):193-196.
- Alvarez-Perea, A., Garcia, A. P., Hernandez, A. L., de, Barrio M., and Baeza, M. L. Urticaria due to aloe vera: a new sensitizer? Ann.Allergy Asthma Immunol. 2010;105(5):404-405. PubMed
- Hogan, D. J. Widespread dermatitis after topical treatment of chronic leg ulcers and stasis dermatitis. CMAJ. 2-15-1988;138(4):336-338.
- Savchak VI. Acute bullous allergic dermatitis due to local application of aloe leaves. Vestnik Dermatologii i Venerologii 1977;12:44-45.
- Nakamura, T. and Kotajima, S. Contact dermatitis from aloe arborescens. Contact Dermatitis 1984;11(1):51. PubMed
- Shoji, A. Contact dermatitis to Aloe arborescens. Contact Dermatitis 1982;8(3):164-167. PubMed
- Morrow, D. M., Rapaport, M. J., and Strick, R. A. Hypersensitivity to aloe. Arch Dermatol. 1980;116(9):1064-1065. DOI
- Cosmetic Ingredient Review Expert Panel. Final report on the safety assessment of AloeAndongensis Extract, Aloe Andongensis Leaf Juice,aloe Arborescens Leaf Extract, Aloe Arborescens Leaf Juice, Aloe Arborescens Leaf Protoplasts, Aloe Barbadensis Flower E
- Bhalang K, Thunyakitpisal P, Rungsirisatean N. Acemannan, a polysaccharide extracted from Aloe vera, is effective in the treatment of oral aphthous ulceration. J Altern Complement Med 2013;19(5):429-34.
- Hajheydari Z, Saeedi M, Morteza-Semnani K, Soltani A. Effect of Aloe vera topical gel combined with tretinoin in treatment of mild and moderate acne vulgaris: a randomized, double-blind, prospective trial. J Dermatolog Treat 2014;25(2):123-9.
- Jiménez-Encarnación E, Ríos G, Muñoz-Mirabal A, Vilá LM. Euforia-induced acute hepatitis in a patient with scleroderma. BMJ Case Rep 2012;2012. PubMed
- Lee J, Lee MS, Nam KW. Acute toxic hepatitis caused by an aloe vera preparation in a young patient: a case report with a literature review. Korean J Gastroenterol 2014;64(1):54-8. PubMed
- Guo X, Mei N. Aloe Vera - A Review of Toxicity and Adverse Clinical Effects. J Environ Sci Health C Environ Carcinog Ecotoxicol Rev 2016;34(2):77-96.
- Hoogenboom TCH, Patel N, Cook NA, Williams R, Taylor-Robinson SD, Lim AKP. The effect of Aloe vera juice on liver enzymes and hepatic structure in a healthy population. Integr Med (Encinitas) 2020;19(3):30-4.
- Mushtaq S, Mushtaq Z, Sarfraz J, et al. Comparison of effect of aloe vera gel with aspirin and celecoxib on platelet aggregation. Professional Med J. 2020; 27(5):973-978. DOI
- Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
- Sabbaghzadegan S, Soltani MH, Kamalinejad M, Bahrami M, Kabir A, Dadmehr M. The effect of a standardized capsule of Aloe vera gel on the quality of life in patients with systolic heart failure: A randomized double-blind placebo-controlled clinical trial.
- Lewis ED, Crowley DC, Guthrie N, Evans M. Healthy adults supplemented with a nutraceutical formulation containing Aloe vera gel, rosemary and Poria cocos enhances the effect of influenza vaccination in a randomized, triple-blind, placebo-controlled trial. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC