Aloe Vera Gel Ingredients & Drug Interactions
by GM Germa
What is this page for?
First and foremost: checking Aloe Vera Gel against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Aloe Vera Gel is a dietary supplement by GM Germa with 1 active ingredient. Its ingredients are commonly taken for minor burns and skin irritation, wound healing, constipation.Based on those ingredients, 461 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Aloe vera extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Aloe Vera Gel by GM Germa
Ask about any prescription or over-the-counter medication and we check it for interactions with Aloe Vera Gel by GM Germa — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Aloe Vera Gel by GM Germa
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product has one active ingredient: aloe vera extract. Aloe is a plant with a gel and a latex (the yellow substance under the leaf skin); this extract contains compounds from the gel that are traditionally used for skin health, digestion, and blood sugar support.
The softgel also contains inactive ingredients — gelatin, purified water, soybean oil, glycerin, and white beeswax — that make up the capsule and help deliver the extract.
Does it work?
Moderate evidence
The evidence we hold shows aloe vera extract is possibly effective for acne, obesity, diabetes, psoriasis, burns, and constipation. That means preliminary research suggests a benefit, but we don't yet have strong proof.
If you're thinking about this product for one of those reasons, talk to your pharmacist or doctor about whether the current evidence fits your situation.
How safe is it?
Well-documented data
Aloe gel is generally well tolerated when taken by mouth at typical doses. However, oral aloe latex — the yellow substance under the leaf — carries a bigger risk of side effects, especially with heavy or long-term use.
Common side effects include abdominal pain, cramps, and diarrhea. Rare but serious effects from overuse include severe potassium loss (hypokalemia), muscle weakness, irregular heartbeat, and pigment spots in the intestines (pseudomelanosis coli), which usually go away once you stop.
Don't take aloe by mouth if you're pregnant — the latex can stimulate the uterus and act as a strong laxative. Avoid it while breastfeeding too, because safety data are limited and the laxative effects could affect your baby.
Meds to double-check
Major interaction found
Check with your pharmacist before taking this if you use digoxin (heart medication) — that's the highest-risk interaction. Also double-check blood thinners (anticoagulants), antiplatelet drugs, diabetes medications, diuretics, stimulant laxatives, warfarin, or any drugs your liver breaks down via CYP1A2 enzymes.
These interactions are documented in our data for aloe vera extract.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.
Aloe vera extract may help with skin, blood sugar, and digestion, but it's not a quick fix and the evidence is still developing. If you take digoxin, blood thinners, diabetes meds, diuretics, or warfarin, you need to check this product with your pharmacist first — the risks are real.
Talk to us before you start, especially if you're pregnant, nursing, or using it long-term.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Aloe Vera Gel, straight from the product label.
| Brand | GM Germa |
|---|---|
| Barcode (UPC) | 790933110104 |
| Net contents | 90 Softgel(s) |
| Market status | On market |
| Date entered into DSLD | Nov 22, 2023 |
| DSLD ID | 303177 |
| Product type | Botanical |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Women (not pregnant or lactating) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Aloe Vera Gel by GM Germa, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Aloe vera extract | 25 mg | -- |
Other ingredients: Gelatin, Water, Purified, Soybean Oil, Glycerin, White Beeswax
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Aloe Vera is a traditional laxative that has been used for centuries as a natural remedy to promote Colon movements.
Aloe Vera Gel is a source of plant nutrients that support general wellness. Aloe Vera Gel 5000 mg per serving
Formulation
Aloe Vera resin is still today's number one natural laxative on the market.
Antioxidant and Antibacterial Properties
Suggested/Recommended/Usage/Directions
Suggested Use: Use as a Dietary Supplement. Take 1 capsule a day, preferably with food or as directed by your doctor.
Precautions
Warning: Do not use if pregnant or nursing, ask a physician before use. Do not use if taking any medication or have any medical condition.
Do not use if allergic to any of the ingredients.
Do not use if any adverse reactions occur. In case of accidental overdose, get medical help or contact a Poison Control Center immediately. Do not use if either seal is torn, broken or missing.
Not intended for use by person under the age of 18. Keep out of the reach of children.
Storage
Store at controlled room temperature between 15 degrees and 30 degrees C (59 degrees-89 degrees F).
Seals/Symbols
Made in USA
General Statements
Please Recycle Questions or Comments: 1-305-278-0033, M-F, 9-5 Eastern
FDA Disclaimer Statement
These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Aloe Vera Gel by GM Germa label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Aloe Vera Gel by GM Germa
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container90 Amounts shown are per serving.
Aloe vera extract
Interacts with461 drugs
Aloe vera gel is widely used on the skin for minor burns and irritation, and some research suggests it may help. Aloe latex (the yellow part) is a str...
Aloe vera extract monograph & interactionsOther (inactive) ingredients: Gelatin, Water, Purified, Soybean Oil, Glycerin, White Beeswax. These complete the product’s ingredient list but are not active constituents.
Aloe Vera Gel by GM Germa Drug Interactions
HelloPharmacist Interaction Report
Aloe Vera Gel by GM Germa contains aloe vera extract, which does interact with several medication types.
The most serious concern is with digoxin (Lanoxin), a heart medication. Overuse of aloe can deplete potassium, which raises the risk of toxicity when combined with digoxin and increases the chance of serious side effects.
Read the full breakdown — every affected drug type, severity by severity
Aloe also has Moderate-severity interactions with blood thinners (anticoagulants) and antiplatelet drugs — the extract can slow blood clotting in lab studies, potentially raising bleeding risk. If you take diabetes medications, aloe may lower blood sugar further, so you'd need close monitoring.
Diuretics (water pills) are a concern too, because aloe overuse can worsen potassium loss. Stimulant laxatives and warfarin (Coumadin) carry similar risks: aloe's laxative effect can compound fluid and electrolyte loss or increase warfarin's bleeding effect.
Aloe also has a Minor interaction with certain drugs broken down by CYP1A2 enzymes — the extract can speed up how your liver clears them, potentially lowering their effectiveness.
Altogether, these interactions span 460 individual medications. Use the medication checker on this page to verify your exact prescriptions before starting.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Aloe Vera Gel?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Aloe Vera Gel interact with 461 drugs. Click any drug to see the details.
1 of the 1 ingredient in Aloe Vera Gel interact with drugs. Each result below shows which ingredient is responsible. Aloe vera extract
DigoxinDigitek, Lanoxicaps, Lanoxin
How Digoxin interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera ExtractDigoxin (lanoxin) Major
Interaction Summary
Theoretically, aloe latex might increase the risk of adverse effects when taken with cardiac glycosides.
Read the full Aloe Vera Extract + Digoxin interactionAbciximabReoPro
How Abciximab interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Extract + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Extract + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera ExtractAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Aloe Vera Extract + Acarbose interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Extract + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Aloe Vera Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera ExtractAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Diuretic Drugs Moderate
Interaction Summary
Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Aloe Vera Extract + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera ExtractAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Extract + Acetaminophen, Ibuprofen interactionAcetaminophen, Pamabrom, PyrilamineMidol Max Strength PMS, Pamprin, Pamprin ES
How Acetaminophen, Pamabrom, Pyrilamine interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Diuretic Drugs Moderate
Interaction Summary
Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Aloe Vera Extract + Acetaminophen, Pamabrom, Pyrilamine interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera ExtractDiuretic Drugs Moderate
Interaction Summary
Theoretically, aloe latex might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Aloe Vera Extract + Acetazolamide interactionAcetohexamideDymelor
How Acetohexamide interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera ExtractAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Aloe Vera Extract + Acetohexamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Extract + Acetylsalicylic Acid interactionAlbiglutideTanzeum
How Albiglutide interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera ExtractAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Aloe Vera Extract + Albiglutide interactionAlogliptinNesina
How Alogliptin interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera ExtractAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Aloe Vera Extract + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera ExtractAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Aloe Vera Extract + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera ExtractAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Aloe Vera Extract + Alogliptin, Pioglitazone interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Extract + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Extract + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Extract + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera ExtractDiuretic Drugs Moderate
Interaction Summary
Theoretically, aloe latex might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Aloe Vera Extract + Amiloride, Hydrochlorothiazide interactionAmmonium ChlorideAmmonium Chloride
How Ammonium Chloride interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera ExtractDiuretic Drugs Moderate
Interaction Summary
Theoretically, aloe latex might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Aloe Vera Extract + Ammonium Chloride interactionAnacaulase-bcdbNexoBrid
How Anacaulase-bcdb interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Extract + Anacaulase-bcdb interactionAnagrelideAgrylin
How Anagrelide interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera ExtractAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Extract + Anagrelide interactionAnisindioneMiradon
How Anisindione interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Extract + Anisindione interactionAntidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) InhibitorGlyxambi
How Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera ExtractAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Aloe Vera Extract + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interactionAntithrombin IiiThrombate III
How Antithrombin Iii interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Extract + Antithrombin Iii interactionApixabanEliquis
How Apixaban interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Extract + Apixaban interactionArgatrobanArgatroban
How Argatroban interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Extract + Argatroban interactionArmodafinilNuvigil
How Armodafinil interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera ExtractStimulant Laxatives Moderate
Interaction Summary
Theoretically, aloe latex might increase the risk for fluid and electrolyte loss when taken with stimulant laxatives.
Read the full Aloe Vera Extract + Armodafinil interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Aloe Vera Gel with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Aloe vera extract
Digoxin (Lanoxin)
Theoretically, aloe latex might increase the risk of adverse effects when taken with cardiac glycosides.
Overuse of aloe latex can increase the risk of adverse effects from cardiac glycoside drugs, such as digoxin, due to potassium depletion. Overuse of aloe, along with cardiac glycoside drugs, can increase the risk of toxicity.
Anticoagulant/Antiplatelet Drugs
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro research shows that aloe gel can inhibit platelet aggregation. This inhibition was greater than that seen with celecoxib, but less than that seen with aspirin.
Antidiabetes Drugs
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Preliminary clinical research suggests aloe gel might lower blood glucose levels and have additive effects when used with antidiabetes drugs. Monitor blood glucose levels closely.
Diuretic Drugs
Theoretically, aloe latex might increase the risk of hypokalemia when taken with diuretic drugs.
Overuse of aloe latex might compound diuretic-induced potassium loss, increasing the risk of hypokalemia.
Stimulant Laxatives
Theoretically, aloe latex might increase the risk for fluid and electrolyte loss when taken with stimulant laxatives.
Due to cathartic laxative effects of aloe latex, concomitant use with other stimulant laxatives might compound fluid and electrolyte loss.
Warfarin (Coumadin)
Theoretically, aloe latex might increase the risk of bleeding when taken with warfarin.
Aloe latex has stimulant laxative effects. In some people aloe latex can cause diarrhea. Diarrhea can increase the effects of warfarin, increase international normalized ratio (INR), and increase the risk of bleeding. Advise patients who take warfarin not to take excessive amounts of aloe vera.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that aloe extract induces CYP1A2 enzymes.
Brand information
Manufacturer and brand details for Aloe Vera Gel, from the product label.
GM Germa
See all GM Germa products- Name
- Germa Products, LLC
- Street Address
- 13121 SW 122 Avenue
- City
- Miami
- State
- FL
- ZipCode
- 33186
- Phone Number
- 1-305-278-0033
- Web Address
- www.germa.net
Aloe Vera Gel by GM Germa: Common Questions
Does Aloe Vera Gel by GM Germa interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this if I'm pregnant?
Can I take this while breastfeeding?
What are the most common side effects?
How does aloe help with constipation?
Is this product the same as aloe you put on sunburns?
Can I take this long-term?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Aloe Vera Gel is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Aloe Vera Gel’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Aloe Vera Gel's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 41 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Aloe 41 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- Wichtl MW. Herbal Drugs and Phytopharmaceuticals. Ed. N.M. Bisset. Stuttgart: Medpharm GmbH Scientific Publishers, 1994.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Nusko G, Schneider B, Schneider I, et al. Anthranoid laxative use is not a risk factor for colorectal neoplasia: results of a prospective case control study. Gut 2000;46:651-5. PubMed
- Luyckx VA, Ballantine R, Claeys M, et al. Herbal remedy-associated acute renal failure secondary to Cape aloes. Am J Kidney Dis 2002;39:E13. PubMed
- Rajasekaran S, Sivagnanam K, Ravi K, Subramanian S. Hypoglycemic effect of Aloe vera gel on streptozotocin-induced diabetes in experimental rats. J Med Food 2004;7:61-6.
- Williams MS, Burk M, Loprinzi CL, et al. Phase III double-blind evaluation of an aloe vera gel as a prophylactic agent for radiation-induced skin toxicity. Int J Radiat Oncol Biol Phys 1996;36:345-9. PubMed
- Vogler BK, Ernst E. Aloe vera: a systematic review of its clinical effectiveness. Br J Gen Pract 1999;49:823-8.
- Bottenberg MM, Wall GC, Harvey RL, Habib S. Oral aloe vera-induced hepatitis. Ann Pharmacother 2007;41:1740-3. PubMed
- Rabe C, Musch A, Schirmacher P, et al. Acute hepatitis induced by an Aloe vera preparation: a case report. World J Gastroenterol 2005;11:303-4. PubMed
- Kanat O, Ozet A, Ataergin S. Aloe vera-induced acute toxic hepatitis in a healthy young man. Eur J Int Med 2006;17:589. PubMed
- Mueller SO, Stopper H. Characterization of the genotoxicity of anthraquinones in mammalian cells. Biochim Biophys Acta 1999;1428:406-14. PubMed
- Schorkhuber M, Richter M, Dutter A, et al. Effect of anthraquinone laxatives on the proliferation and urokinase secretion of normal, premalignant and malignant colonic epithelial cells. Eur J Cancer 1998;34:1091-8. PubMed
- Yang HN, Kim DJ, Kim YM, et al. Aloe-induced toxic hepatitis. J Korean Med Sci 2010;25:492-5. PubMed
- Choonhakarn C, Busaracome P, Sripanidkulchai B, et al. A prospective, randomized clinical trial comparing topical aloe vera with 0.1% triamcinolone acetonide in mild to moderate plaque psoriasis. J.Eur.Acad.Dermatol.Venereol. 2010;24:168-72. PubMed
- Ishii Y, Tanizawa H, Takino Y. Studies of aloe. IV. Mechanism of cathartic effect. (3). Biol Pharm Bull. 1994;17:495-7. PubMed
- Ishii Y, Tanizawa H, Takino Y. Studies of aloe. V. Mechanism of cathartic effect. (4). Biol Pharm Bull. 1994;17:651-3. PubMed
- Nelemans FA. Clinical and toxicological aspects of anthraquinone laxatives. Pharmacology. 1976;14 Suppl 1:73-7. PubMed
- Paulsen E, Korsholm L, Brandrup F. A double-blind, placebo-controlled study of a commercial Aloe vera gel in the treatment of slight to moderate psoriasis vulgaris. J Eur Acad Dermatol Venereol. 2005;19:326-31.
- Huseini HF, Kianbakht S, Hajiaghaee R, et al. Anti-hyperglycemic and anti-hypercholesterolemic effects of Aloe vera leaf gel in hyperlipidemic type 2 diabetic patients: a randomized double-blind placebo-controlled clinical trial. Planta Med. 2012;78:311-6
- Ferreira, M., Teixeira, M., Silva, E., and Selores, M. Allergic contact dermatitis to Aloe vera. Contact Dermatitis 2007;57(4):278-279.
- Choonhakarn, C., Busaracome, P., Sripanidkulchai, B., and Sarakarn, P. The efficacy of aloe vera gel in the treatment of oral lichen planus: a randomized controlled trial. Br J Dermatol 2008;158(3):573-577. PubMed
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