Aloe Vera Gels Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Aloe Vera Gels against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Aloe Vera Gels is a dietary supplement by Douglas Cooper Co. with 1 active ingredient. Its ingredients are commonly taken for minor burns and skin irritation, wound healing, constipation.Based on those ingredients, 461 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Aloe Vera. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Aloe Vera Gels by Douglas Cooper Co.
Ask about any prescription or over-the-counter medication and we check it for interactions with Aloe Vera Gels by Douglas Cooper Co. — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Aloe Vera Gels by Douglas Cooper Co.
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product has one active ingredient: aloe vera. The other ingredients — extra virgin olive oil, gelatin, water, glycerin, and silica — are inactive excipients that help form and stabilize the softgel capsule.
Does it work?
Moderate evidence
Aloe vera shows possibly effective evidence for several uses in the data we hold: acne, obesity, diabetes, psoriasis, burns, and constipation. That means there's some clinical support, but the evidence isn't conclusive.
If you're considering it for one of these reasons, a conversation with your pharmacist or doctor about what the research actually shows for your situation is worth having.
How safe is it?
Well-documented data
Topical aloe gel is generally well tolerated. Oral aloe latex — the substance in this product — carries greater risk, especially at high doses or with long-term use.
The most common side effects from oral aloe are abdominal pain, cramps, and diarrhea. Long-term use can cause serious effects like potassium loss (hypokalemia), muscle weakness, and irregular heartbeat.
There's also a rare condition called pseudomelanosis coli (dark pigment spots in the intestines) that usually reverses when you stop taking aloe. During pregnancy, aloe may stimulate the uterus and act as a strong laxative — the safety data advises against it.
While breastfeeding, there isn't enough safety data, and the laxative effects are a concern, so it's best to avoid it or talk with your doctor or pharmacist.
Meds to double-check
Major interaction found
Check before you take this if you use digoxin or other heart medications (cardiac glycosides) — this is the most serious risk. Also double-check if you're on blood thinners (anticoagulants), antiplatelet drugs, diabetes medications, diuretics, stimulant laxatives, warfarin, or any drugs your liver breaks down under the CYP1A2 pathway.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.
Aloe vera may help with acne, burns, constipation, and other conditions, but it interacts with heart, blood-thinning, diabetes, and diuretic medications — and many others. If you take any prescription drugs, especially for your heart, blood clotting, or blood sugar, check them against the interactions tool before you start.
Pregnant or breastfeeding? Skip this one.
Talk to your pharmacist about whether it's right for you.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2022.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Aloe Vera Gels, straight from the product label.
| Brand | Douglas Cooper Co. |
|---|---|
| Net contents | 100 Softgel(s) |
| Market status | On market |
| Date entered into DSLD | Oct 24, 2022 |
| DSLD ID | 275194 |
| Product type | Botanical |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Aloe Vera Gels by Douglas Cooper Co., sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Total Fat | 0.5 Gram(s) | 1% |
| Calories | 5 Calorie(s) | -- |
| Aloe Vera | 100 mg | -- |
Other ingredients: Extra Virgin Olive Oil, Gelatin, Water, Glycerin, Silica
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested Usage: Take 2 softgels 1 to 2 times daily, on an empty stomach.
Formula
Aloe Vera offers a variety of nutrients, including vitamins, minerals, enzymes and amino acids. Aloe Vera's constituent mucopolysaccharides, also known as glycosaminoglycans (GAGs), are thought to be its active components.
10,000 mg equivalency
Formulation
Scientific studies have indicated that Aloe can help to support the body's own healing processes. In addition, Aloe Vera has been shown to support a healthy digestive system.
Natural color variation may occur in this product. Naturally occurring particulates may be visible in the aloe vera.
Not manufactured with yeast, wheat, gluten, soy, corn, milk, egg, fish or shellfish ingredients. Non-GMO
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Precautions
Caution: For adults only.
Consult a physician if pregnant/nursing, taking medication, or have a medical condition.
Keep out of reach of children.
To report a serious adverse event, or for product information, contact 1-800-234-8686
Not manufactured with yeast, wheat, gluten, soy, corn, milk, egg, fish or shellfish ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.
Storage
Store in a cool, dry place after opening.
General Statements
Please recycle.
Brand IP Statement(s)
Douglas Cooper Co. "Trace minerals make the difference" since 1950
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Aloe Vera Gels by Douglas Cooper Co. label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Aloe Vera Gels by Douglas Cooper Co.
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size2 Softgel(s) Dosage formSoftgel Capsule Servings per container50 Amounts shown are per serving.
Aloe Vera
Interacts with461 drugs
Aloe vera gel is widely used on the skin for minor burns and irritation, and some research suggests it may help. Aloe latex (the yellow part) is a str...
Aloe Vera monograph & interactionsOther (inactive) ingredients: Extra Virgin Olive Oil, Gelatin, Water, Glycerin, Silica. These complete the product’s ingredient list but are not active constituents.
Aloe Vera Gels by Douglas Cooper Co. Drug Interactions
HelloPharmacist Interaction Report
Aloe Vera Gels by Douglas Cooper Co. contains aloe vera, which does interact with several medication types.
The most serious concern is digoxin (a heart medication). Overuse of aloe can deplete potassium, which raises the risk of toxicity and adverse effects when you're taking digoxin.
Read the full breakdown — every affected drug type, severity by severity
Aloe also interacts with blood thinners (anticoagulants) and antiplatelet drugs at a moderate level — aloe gel can slow how your blood clots, raising bleeding risk. It may lower blood sugar (hypoglycemia) if you're on diabetes medications, so you'd need to monitor your levels closely.
Diuretics (water pills) and stimulant laxatives carry moderate risk too, since aloe can worsen potassium loss and fluid imbalance. Warfarin (Coumadin) is a concern because aloe's laxative effects can cause diarrhea, which makes warfarin stronger and increases bleeding risk.
Aloe may also interfere with certain drugs your liver breaks down (CYP1A2 substrates), though this is a minor interaction.
Aloe vera is the only active ingredient in this product, and it's the one we have interaction data for. Altogether, these interactions span 460 individual medications.
Please check your exact medications with the search tool on this page before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Aloe Vera Gels?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Aloe Vera Gels interact with 461 drugs. Click any drug to see the details.
1 of the 1 ingredient in Aloe Vera Gels interact with drugs. Each result below shows which ingredient is responsible. Aloe Vera
DigoxinDigitek, Lanoxicaps, Lanoxin
How Digoxin interacts with Aloe Vera Gels — through 1 ingredient. Tap an ingredient for the detail:
Aloe VeraDigoxin (lanoxin) Major
Interaction Summary
Theoretically, aloe latex might increase the risk of adverse effects when taken with cardiac glycosides.
Read the full Aloe Vera + Digoxin interactionAbciximabReoPro
How Abciximab interacts with Aloe Vera Gels — through 1 ingredient. Tap an ingredient for the detail:
Aloe VeraAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Aloe Vera Gels — through 1 ingredient. Tap an ingredient for the detail:
Aloe VeraAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Aloe Vera Gels — through 1 ingredient. Tap an ingredient for the detail:
Aloe VeraAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Aloe Vera + Acarbose interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Aloe Vera Gels — through 1 ingredient. Tap an ingredient for the detail:
Aloe VeraAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Aloe Vera Gels — through 1 ingredient. Tap an ingredient for the detail:
Aloe VeraCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Aloe Vera + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Aloe Vera Gels — through 1 ingredient. Tap an ingredient for the detail:
Aloe VeraAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Aloe Vera Gels — through 1 ingredient. Tap an ingredient for the detail:
Aloe VeraCytochrome P450 1a2 (cyp1a2) Substrates, Diuretic Drugs Moderate
Interaction Summary
Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Aloe Vera + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Aloe Vera Gels — through 1 ingredient. Tap an ingredient for the detail:
Aloe VeraAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera + Acetaminophen, Ibuprofen interactionAcetaminophen, Pamabrom, PyrilamineMidol Max Strength PMS, Pamprin, Pamprin ES
How Acetaminophen, Pamabrom, Pyrilamine interacts with Aloe Vera Gels — through 1 ingredient. Tap an ingredient for the detail:
Aloe VeraCytochrome P450 1a2 (cyp1a2) Substrates, Diuretic Drugs Moderate
Interaction Summary
Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Aloe Vera + Acetaminophen, Pamabrom, Pyrilamine interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Aloe Vera Gels — through 1 ingredient. Tap an ingredient for the detail:
Aloe VeraDiuretic Drugs Moderate
Interaction Summary
Theoretically, aloe latex might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Aloe Vera + Acetazolamide interactionAcetohexamideDymelor
How Acetohexamide interacts with Aloe Vera Gels — through 1 ingredient. Tap an ingredient for the detail:
Aloe VeraAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Aloe Vera + Acetohexamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Aloe Vera Gels — through 1 ingredient. Tap an ingredient for the detail:
Aloe VeraAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera + Acetylsalicylic Acid interactionAlbiglutideTanzeum
How Albiglutide interacts with Aloe Vera Gels — through 1 ingredient. Tap an ingredient for the detail:
Aloe VeraAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Aloe Vera + Albiglutide interactionAlogliptinNesina
How Alogliptin interacts with Aloe Vera Gels — through 1 ingredient. Tap an ingredient for the detail:
Aloe VeraAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Aloe Vera + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Aloe Vera Gels — through 1 ingredient. Tap an ingredient for the detail:
Aloe VeraAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Aloe Vera + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Aloe Vera Gels — through 1 ingredient. Tap an ingredient for the detail:
Aloe VeraAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Aloe Vera + Alogliptin, Pioglitazone interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with Aloe Vera Gels — through 1 ingredient. Tap an ingredient for the detail:
Aloe VeraAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Aloe Vera Gels — through 1 ingredient. Tap an ingredient for the detail:
Aloe VeraAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Aloe Vera Gels — through 1 ingredient. Tap an ingredient for the detail:
Aloe VeraAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with Aloe Vera Gels — through 1 ingredient. Tap an ingredient for the detail:
Aloe VeraDiuretic Drugs Moderate
Interaction Summary
Theoretically, aloe latex might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Aloe Vera + Amiloride, Hydrochlorothiazide interactionAmmonium ChlorideAmmonium Chloride
How Ammonium Chloride interacts with Aloe Vera Gels — through 1 ingredient. Tap an ingredient for the detail:
Aloe VeraDiuretic Drugs Moderate
Interaction Summary
Theoretically, aloe latex might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Aloe Vera + Ammonium Chloride interactionAnacaulase-bcdbNexoBrid
How Anacaulase-bcdb interacts with Aloe Vera Gels — through 1 ingredient. Tap an ingredient for the detail:
Aloe VeraAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera + Anacaulase-bcdb interactionAnagrelideAgrylin
How Anagrelide interacts with Aloe Vera Gels — through 1 ingredient. Tap an ingredient for the detail:
Aloe VeraAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera + Anagrelide interactionAnisindioneMiradon
How Anisindione interacts with Aloe Vera Gels — through 1 ingredient. Tap an ingredient for the detail:
Aloe VeraAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera + Anisindione interactionAntidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) InhibitorGlyxambi
How Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interacts with Aloe Vera Gels — through 1 ingredient. Tap an ingredient for the detail:
Aloe VeraAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Aloe Vera + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interactionAntithrombin IiiThrombate III
How Antithrombin Iii interacts with Aloe Vera Gels — through 1 ingredient. Tap an ingredient for the detail:
Aloe VeraAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera + Antithrombin Iii interactionApixabanEliquis
How Apixaban interacts with Aloe Vera Gels — through 1 ingredient. Tap an ingredient for the detail:
Aloe VeraAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera + Apixaban interactionArgatrobanArgatroban
How Argatroban interacts with Aloe Vera Gels — through 1 ingredient. Tap an ingredient for the detail:
Aloe VeraAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera + Argatroban interactionArmodafinilNuvigil
How Armodafinil interacts with Aloe Vera Gels — through 1 ingredient. Tap an ingredient for the detail:
Aloe VeraStimulant Laxatives Moderate
Interaction Summary
Theoretically, aloe latex might increase the risk for fluid and electrolyte loss when taken with stimulant laxatives.
Read the full Aloe Vera + Armodafinil interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Aloe Vera Gels with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Aloe Vera
Digoxin (Lanoxin)
Theoretically, aloe latex might increase the risk of adverse effects when taken with cardiac glycosides.
Overuse of aloe latex can increase the risk of adverse effects from cardiac glycoside drugs, such as digoxin, due to potassium depletion. Overuse of aloe, along with cardiac glycoside drugs, can increase the risk of toxicity.
Anticoagulant/Antiplatelet Drugs
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro research shows that aloe gel can inhibit platelet aggregation. This inhibition was greater than that seen with celecoxib, but less than that seen with aspirin.
Antidiabetes Drugs
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Preliminary clinical research suggests aloe gel might lower blood glucose levels and have additive effects when used with antidiabetes drugs. Monitor blood glucose levels closely.
Diuretic Drugs
Theoretically, aloe latex might increase the risk of hypokalemia when taken with diuretic drugs.
Overuse of aloe latex might compound diuretic-induced potassium loss, increasing the risk of hypokalemia.
Stimulant Laxatives
Theoretically, aloe latex might increase the risk for fluid and electrolyte loss when taken with stimulant laxatives.
Due to cathartic laxative effects of aloe latex, concomitant use with other stimulant laxatives might compound fluid and electrolyte loss.
Warfarin (Coumadin)
Theoretically, aloe latex might increase the risk of bleeding when taken with warfarin.
Aloe latex has stimulant laxative effects. In some people aloe latex can cause diarrhea. Diarrhea can increase the effects of warfarin, increase international normalized ratio (INR), and increase the risk of bleeding. Advise patients who take warfarin not to take excessive amounts of aloe vera.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that aloe extract induces CYP1A2 enzymes.
Brand information
Manufacturer and brand details for Aloe Vera Gels, from the product label.
Douglas Cooper Co.
See all Douglas Cooper Co. products- Name
- Douglas Cooper Co.
- Street Address
- 377 Ridge Point Dr
- City
- Carmel
- State
- IN
- ZipCode
- 46032
- Phone Number
- 1-800-234-8686
Aloe Vera Gels by Douglas Cooper Co.: Common Questions
Does Aloe Vera Gels by Douglas Cooper Co. interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this if I'm pregnant or breastfeeding?
What are the side effects I should watch for?
Does this actually work for constipation?
Can I use this long-term?
What's the difference between aloe gel and aloe latex?
What inactive ingredients are in this product?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Aloe Vera Gels is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Aloe Vera Gels’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Aloe Vera Gels's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 41 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Aloe 41 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- Wichtl MW. Herbal Drugs and Phytopharmaceuticals. Ed. N.M. Bisset. Stuttgart: Medpharm GmbH Scientific Publishers, 1994.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Nusko G, Schneider B, Schneider I, et al. Anthranoid laxative use is not a risk factor for colorectal neoplasia: results of a prospective case control study. Gut 2000;46:651-5. PubMed
- Luyckx VA, Ballantine R, Claeys M, et al. Herbal remedy-associated acute renal failure secondary to Cape aloes. Am J Kidney Dis 2002;39:E13. PubMed
- Rajasekaran S, Sivagnanam K, Ravi K, Subramanian S. Hypoglycemic effect of Aloe vera gel on streptozotocin-induced diabetes in experimental rats. J Med Food 2004;7:61-6.
- Williams MS, Burk M, Loprinzi CL, et al. Phase III double-blind evaluation of an aloe vera gel as a prophylactic agent for radiation-induced skin toxicity. Int J Radiat Oncol Biol Phys 1996;36:345-9. PubMed
- Vogler BK, Ernst E. Aloe vera: a systematic review of its clinical effectiveness. Br J Gen Pract 1999;49:823-8.
- Bottenberg MM, Wall GC, Harvey RL, Habib S. Oral aloe vera-induced hepatitis. Ann Pharmacother 2007;41:1740-3. PubMed
- Rabe C, Musch A, Schirmacher P, et al. Acute hepatitis induced by an Aloe vera preparation: a case report. World J Gastroenterol 2005;11:303-4. PubMed
- Kanat O, Ozet A, Ataergin S. Aloe vera-induced acute toxic hepatitis in a healthy young man. Eur J Int Med 2006;17:589. PubMed
- Mueller SO, Stopper H. Characterization of the genotoxicity of anthraquinones in mammalian cells. Biochim Biophys Acta 1999;1428:406-14. PubMed
- Schorkhuber M, Richter M, Dutter A, et al. Effect of anthraquinone laxatives on the proliferation and urokinase secretion of normal, premalignant and malignant colonic epithelial cells. Eur J Cancer 1998;34:1091-8. PubMed
- Yang HN, Kim DJ, Kim YM, et al. Aloe-induced toxic hepatitis. J Korean Med Sci 2010;25:492-5. PubMed
- Choonhakarn C, Busaracome P, Sripanidkulchai B, et al. A prospective, randomized clinical trial comparing topical aloe vera with 0.1% triamcinolone acetonide in mild to moderate plaque psoriasis. J.Eur.Acad.Dermatol.Venereol. 2010;24:168-72. PubMed
- Ishii Y, Tanizawa H, Takino Y. Studies of aloe. IV. Mechanism of cathartic effect. (3). Biol Pharm Bull. 1994;17:495-7. PubMed
- Ishii Y, Tanizawa H, Takino Y. Studies of aloe. V. Mechanism of cathartic effect. (4). Biol Pharm Bull. 1994;17:651-3. PubMed
- Nelemans FA. Clinical and toxicological aspects of anthraquinone laxatives. Pharmacology. 1976;14 Suppl 1:73-7. PubMed
- Paulsen E, Korsholm L, Brandrup F. A double-blind, placebo-controlled study of a commercial Aloe vera gel in the treatment of slight to moderate psoriasis vulgaris. J Eur Acad Dermatol Venereol. 2005;19:326-31.
- Huseini HF, Kianbakht S, Hajiaghaee R, et al. Anti-hyperglycemic and anti-hypercholesterolemic effects of Aloe vera leaf gel in hyperlipidemic type 2 diabetic patients: a randomized double-blind placebo-controlled clinical trial. Planta Med. 2012;78:311-6
- Ferreira, M., Teixeira, M., Silva, E., and Selores, M. Allergic contact dermatitis to Aloe vera. Contact Dermatitis 2007;57(4):278-279.
- Choonhakarn, C., Busaracome, P., Sripanidkulchai, B., and Sarakarn, P. The efficacy of aloe vera gel in the treatment of oral lichen planus: a randomized controlled trial. Br J Dermatol 2008;158(3):573-577. PubMed
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