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Dietary supplement

Amino Acid Complex 2000 Ingredients & Drug Interactions

by NusaPure

Amino Acid Complex 2000 label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Amino Acid Complex 2000 against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Amino Acid Complex 2000 is a dietary supplement by NusaPure with 3 active ingredients.Based on those ingredients, 504 medications have a known interaction with it, the most serious rated major. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Amino Acid Complex 2000 by NusaPure

Ask about any prescription or over-the-counter medication and we check it for interactions with Amino Acid Complex 2000 by NusaPure — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Amino Acid Complex 2000 by NusaPure

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 8 active ingredients.
  • “Amino Acid Complex blend” is a proprietary blend — the label gives one combined amount (2,000 mg) without saying how much of each component you get.
  • “Bound Amino Acid Source Blend” is a proprietary blend — the label doesn't break down how much of each component you get.
  • “Plus Amino Acid Blend” is a proprietary blend — the label doesn't break down how much of each component you get.

NusaPure Amino Acid Complex 2000 contains 8 active ingredients: L-Glutamine, Whey Protein Isolate, L-Arginine, Soy Protein Isolate, L-Ornithine, L-Glutathione, Sodium Caseinate, and Bovine Hydrolyzed Collagen. These are amino acids and protein sources designed to support muscle function and recovery.

The product also contains inactive ingredients (cellulose, silica, magnesium stearate, and rice flour) that help hold the capsule together and improve stability.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Muscle building, recovery and athletic performance.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle damage, Exercise-induced muscle soreness, Muscle strength, Postoperative recovery, Critical illness (trauma) — and 3 related terms.
  • The strongest evidence on file: Ornithine is rated "Possibly Effective" for Athletic performance (Natural Medicines).
  • Also on file: Whey Protein is rated "Possibly Effective" for Athletic performance.
  • Also on file: Glutamine is rated "Possibly Effective" for Critical illness (trauma), Postoperative recovery.

The evidence for this product's ingredients is mixed and depends on the specific use. L-Glutamine is effective for sickle cell disease and possibly effective for HIV/AIDS-related wasting, postoperative recovery, and critical illness from trauma.

Whey Protein may help athletic performance but showed no clear benefit for bone health or COPD. L-Ornithine is possibly effective for athletic performance.

L-Arginine has no established effectiveness ratings in our data. Sodium Caseinate and Bovine Hydrolyzed Collagen show insufficient evidence or no clear benefit for most uses, though collagen may help with aging and dry skin.

Overall, the evidence doesn't establish that this blend works for any single condition—talk with your pharmacist about what you're trying to achieve.

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 5 of the 6 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 6 of 6.
  • General safety write-ups exist for 6 of 6.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Most of these ingredients are generally well tolerated in healthy adults at normal doses. L-Glutamine is likely safe during pregnancy and lactation.

L-Arginine is possibly safe in pregnancy but data on lactation is incomplete; it can lower blood pressure, so caution is advised. L-Ornithine should be avoided during pregnancy and breastfeeding due to insufficient safety data.

Whey Protein and Sodium Caseinate are generally well tolerated as food proteins; high-dose supplements haven't been extensively studied. Bovine Hydrolyzed Collagen is not well studied in pregnancy and lactation.

Common side effects from these ingredients include bloating, nausea, diarrhea, constipation, and headache. People with kidney or liver disease should use L-Glutamine only under medical supervision.

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 3 of the 6 matched ingredients can interact with medications — Whey Protein, L-arginine, Glutamine.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; seizure medications; diabetes medications; Parkinson's medications.
  • For scale: 504 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking NusaPure Amino Acid Complex 2000, double-check with your pharmacist if you take levodopa (Parkinson's medication)—a Major interaction. Also verify any blood pressure medications, blood thinners, diabetes medications, potassium-sparing diuretics, ACE inhibitors, ARBs, antibiotics (especially quinolones or tetracyclines), bisphosphonates, or erectile dysfunction medications like sildenafil.

These carry Moderate interactions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

This amino acid blend is a multi-ingredient product with strong interactions involving levodopa and blood pressure medications—if you take any prescription drugs, check them against the tool on this page before starting. The evidence for its effectiveness is limited and ingredient-specific.

It's generally well tolerated in healthy adults, but not well studied as a concentrated supplement in pregnancy or breastfeeding. Talk with your pharmacist about whether it fits your health goals and whether it's safe for you personally.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 6 of 8 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Amino Acid Complex 2000, straight from the product label.

Brand NusaPure
Barcode (UPC) X001WSPRVH
Net contents 180 Veg Cap(s)
Market status On market
Date entered into DSLD Mar 25, 2021
DSLD ID 246057
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Amino Acid Complex 2000 by NusaPure, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
4 Veg Capsule(s)
Maximum serving Sizes:
4 Veg Capsule(s)
Servings per container
45
UPC/BARCODE
X001WSPRVH
IngredientAmount% DV
Calories7 Calorie(s)--
L-Glutamine0 NP--
Protein1.4 Gram(s)2.8%
Whey Protein Isolate0 NP--
L-Arginine0 NP--
Soy Protein isolate0 NP--
L-Ornithine0 NP--
L-Glutathione0 NP--
Sodium Caseinate0 NP--
Amino Acid Complex blend2000 mg--
Bound Amino Acid Source Blend0 NP--
Bovine Hydrolyzed Collagen0 NP--
Plus Amino Acid Blend0 NP--

Other ingredients: Cellulose, Silica, Magnesium Stearate, Rice Flour

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: Take four (4) capsules 2-3 times daily. Take with meals, preferably juice, a few hours before or after taking other medications or health care products.

Precautions

Warning: For adults only.

If you are pregnant or nursing or taking any medications, consult your doctor before use.

Do not use if you have sickle cell anemia, hypertension, gout, decreased platelet count, elevated blood-urea nitrogen, serum creatinine and creatinine, delayed menses, asthma, hypersensitivity to L-Ornithine, ornithine supplements, or are Ornithine Delta-Aminotransferase deficient. Do not exceed recommended dosage.

Allergen information: Not manufactured with wheat, gluten, egg, fish, shellfish or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens. Contains milk and soy.

Keep out of reach of children.

Formulation

Allergen information: Not manufactured with wheat, gluten, egg, fish, shellfish or tree nut ingredients.

Natural color variation may occur in this product.

GMO Free Made with non-GMO Ingredients Gluten Free FDA Registered Facility

Assembled in USA Tested

Supports development of lean muscle mass Supports proper protein synthesis Max Strength

Storage

Store in a cool dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

Premium Quality Assembled in USA GMO Free Made with non-GMO Ingredients Gluten Free FDA Registered Facility

Manufactured in a cGMP Inspected Facility

Formula

Full spectrum amino acid supplement

General Statements

Typical Amino Acid Profile (example) (per serving) Essential Amino Acids: L-Histidine, L-Isoleucine, L-Leucine, L-Lysine, L-Methione, L-Phenylaline, L-Threonine, L-Trypotphan, L-Valine Non-Essential Amino Acids: L-Alanine, L-Arganine, L-Aspartic Acid, L-Cysteine, L-Glutamic Acid, L-Glutamine, Gylcine, L-Hydroxyproline, L-Ornithine, L-Proline, L-Serine, L-Tyrosine Subject to natural variability

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Amino Acid Complex 2000 by NusaPure label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Amino Acid Complex 2000 label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Amino Acid Complex 2000 by NusaPure

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size4 Veg Capsule(s) Dosage formCapsule Servings per container45 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Protein

1.4 Gram(s) per serving

Amino Acid Complex blend

2000 mg per serving
  • › Bound Amino Acid Source Blend
  • › Plus Amino Acid Blend

Other (inactive) ingredients: Cellulose, Silica, Magnesium Stearate, Rice Flour. These complete the product’s ingredient list but are not active constituents.

Interaction report

Amino Acid Complex 2000 by NusaPure Drug Interactions

Want to check YOUR meds against Amino Acid Complex 2000?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
504Drugs
5 Major 491 Moderate 8 Minor

Ingredients driving the most interactions

Individual Drug Interactions

The ingredients in Amino Acid Complex 2000 interact with 504 drugs. Click any drug to see the details.

0 of the 3 ingredients in Amino Acid Complex 2000 interact with drugs. Each result below shows which ingredient is responsible.

Each ingredient & the kinds of drugs it affects

For each ingredient in Amino Acid Complex 2000 with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

The maker

Brand information

Manufacturer and brand details for Amino Acid Complex 2000, from the product label.

NusaPure

See all NusaPure products
Name
Gmax Central LLC
Street Address
4700 Millenia Boulevard, Suite 175 PMB 92909
City
Orlando
State
FL
ZipCode
32839
Pharmacist Counseling Corner

Amino Acid Complex 2000 by NusaPure: Common Questions

Does Amino Acid Complex 2000 by NusaPure interact with any medications?
Yes. Based on its ingredients, Amino Acid Complex 2000 has a known interaction with 504 medications, including 5 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Amino Acid Complex 2000 contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
It depends on which ingredient you're asking about. L-Glutamine is likely safe during pregnancy and breastfeeding. L-Arginine is possibly safe in pregnancy but we don't have enough data on breastfeeding. L-Ornithine should be avoided in both—not enough safety data exists. For the others, safety data during pregnancy and breastfeeding is incomplete or absent. Talk with your doctor before using this product if you're pregnant or breastfeeding.
Does whey protein in this product interact with antibiotics?
Yes. Whey protein contains minerals like calcium that can bind to certain antibiotics in your stomach and reduce how much your body absorbs. If you take quinolone or tetracycline antibiotics, take them at least 2 hours before or 4–6 hours after this product. Ask your pharmacist about your specific antibiotic.
What are the most common side effects?
The most common side effects are digestive: bloating, nausea, diarrhea, constipation, and gas. Headache, abdominal pain, and flushing are also reported. Most are dose-related and mild, but stop and call your doctor if you experience chest pain, severe headache, or difficulty breathing.
Will this help me build muscle or improve athletic performance?
Some ingredients—L-Glutamine and L-Ornithine—are possibly effective for athletic performance. Whey protein and casein are protein sources that support muscle protein synthesis. But this product as a whole hasn't been tested for athletic performance, and the evidence for individual ingredients is limited. Your diet, training, and overall routine matter far more.
Is this safe if I have kidney or liver disease?
Not without medical supervision. L-Glutamine in particular requires close monitoring if you have kidney or liver disease. Talk to your doctor before using this product.
What's the difference between the amino acids in this product?
Each amino acid has a different role. L-Glutamine supports gut and immune function. L-Arginine affects blood vessels and blood pressure. L-Ornithine and L-Glutathione support cellular function and antioxidant defense. The whey, casein, soy proteins, and collagen are amino acid sources that help your muscles repair after exercise or stress.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Amino Acid Complex 2000 is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Amino Acid Complex 2000 label
Sources

Sources & How We Checked

Amino Acid Complex 2000's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 166 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutamine 11 references
  1. Miller AL. Therapeutic considerations of L-glutamine: a review of the literature. Altern Med Rev 1999;4:239-48..
  2. Bozzetti F, Biganzoli L, Gavazzi C, et al. Glutamine supplementation in cancer patients receiving chemotherapy: a double-blind randomized study. Nutrition 1997;13:748-51.. PubMed
  3. Mebane AH. L-Glutamine and mania. Am J Psychiatry 984;141:1302-3.
  4. Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000;130:1007S-15S.. PubMed
  5. Garlick PJ. Assessment of the safety of glutamine and other amino acids. J Nutr 2001;131:2556S-61S.. PubMed
  6. Chapman AG. Glutamate and epilepsy. J Nutr 2000;130:1043S-5S.. PubMed
  7. Ziegler TR. Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy. J Nutr 2001;131:2578S-84S.. PubMed
  8. Laviano A, Molfino A, Lacaria MT, Canelli A, De Leo S, Preziosa I, Rossi Fanelli F. Glutamine supplementation favors weight loss in nondieting obese female patients. A pilot study. Eur J Clin Nutr. 2014 Nov;68(11):1264-6. PubMed
  9. Endari (l-glutamine) [package insert]. Torrance, CA: Emmaus Medical,Inc; 2017.
  10. Niihara Y, Miller ST, Kanter J, et al. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. N Engl J Med 2018;379(3):226-35. doi: 10.1056/NEJMoa1715971.
  11. Ogden HB, Child RB, Fallowfield JL, et al. Gastrointestinal Tolerance of Low, Medium and High Dose Acute Oral l-Glutamine Supplementation in Healthy Adults: A Pilot Study. Nutrients. 2020;12(10):2953. PubMed

See these in context on the Glutamine monograph →

Whey Protein 25 references
  1. Martindale W. Martindale the Extra Pharmacopoeia. Pharmaceutical Press, 1999.
  2. Maton PN, Burton ME. Antacids revisited: a review of their clinical pharmacology and recommended therapeutic use. Drugs 1999;57:855-70.
  3. Bell SJ. Whey protein concentrates with and without immunoglobulins: a review. J Med Food 2000;3:1-13. PubMed
  4. Nutt JG, Woodward WR, Hammerstad JP, et al. The "on-off" phenomenon in Parkinson's disease. Relation to levodopa absorption and transport. N Engl J Med 1984;310:483-8. PubMed
  5. Baruzzi A, Contin M, Riva R, et al. Influence of meal ingestion time on pharmacokinetics of orally administered levodopa in parkinsonian patients. Clin Neuropharmacol 1987;10:527-37. PubMed
  6. Juncos JL, Fabbrini G, Mouradian MM, et al. Dietary influences on the antiparkinsonian response to levodopa. Arch Neurol 1987;44:1003-5. PubMed
  7. Eriksson T, Granerus AK, Linde A, et al. "On-off" phenomenon in Parkinson's disease: relationship between dopa and other large neutral amino acids in plasma. Neurology 1988;38:1245-8. PubMed
  8. Semla TP, Beizer JL, Higbee MD. Geriatric Dosage Handbook. 4th ed. Hudson, OH: Lexicomp, 1998.
  9. Pletz MW, Petzold P, Allen A, et al. Effect of calcium carbonate on bioavailability of orally administered gemifloxacin. Antimicrob Agents Chemother 2003;47:2158-60.. PubMed
  10. Peters ML, Leonard M, Licata AA. Role of alendronate and risedronate in preventing and treating osteoporosis. Cleve Clin J Med 2001;68:945-51. PubMed
  11. Micke, P., Beeh, K. M., and Buhl, R. Effects of long-term supplementation with whey proteins on plasma glutathione levels of HIV-infected patients. Eur.J Nutr 2002;41(1):12-18. PubMed
  12. Chitapanarux, T., Tienboon, P., Pojchamarnwiputh, S., and Leelarungrayub, D. Open-labeled pilot study of cysteine-rich whey protein isolate supplementation for nonalcoholic steatohepatitis patients. J Gastroenterol.Hepatol. 2009;24(6):1045-1050. PubMed
  13. Sataloff, R. T., Bittermann, T., Marks, L., Lurie, D., and Hawkshaw, M. The effects of glutathione enhancement on sensorineural hearing loss. Ear Nose Throat J 2010;89(9):422-433.
  14. Zhu, K., Meng, X., Kerr, D. A., Devine, A., Solah, V., Binns, C. W., and Prince, R. L. The effects of a two-year randomized, controlled trial of whey protein supplementation on bone structure, IGF-1, and urinary calcium excretion in older postmenopausal
  15. Bjorkman, M. P., Pilvi, T. K., Kekkonen, R. A., Korpela, R., and Tilvis, R. S. Similar effects of leucine rich and regular dairy products on muscle mass and functions of older polymyalgia rheumatica patients: a randomized crossover trial. J Nutr Health A
  16. Brun, A. C., Stordal, K., Johannesdottir, G. B., Bentsen, B. S., and Medhus, A. W. The effect of protein composition in liquid meals on gastric emptying rate in children with cerebral palsy. Clin.Nutr 2012;31(1):108-112. PubMed
  17. Gouni-Berthold, I., Schulte, D. M., Krone, W., Lapointe, J. F., Lemieux, P., Predel, H. G., and Berthold, H. K. The whey fermentation product malleable protein matrix decreases TAG concentrations in patients with the metabolic syndrome: a randomised plac
  18. Errichiello, L., Pezzella, M., Santulli, L., Striano, S., Zara, F., Minetti, C., Mainardi, P., and Striano, P. A proof-of-concept trial of the whey protein alfa-lactalbumin in chronic cortical myoclonus. Mov Disord. 2011;26(14):2573-2575. PubMed
  19. Carcillo, J. A., Dean, J. M., Holubkov, R., Berger, J., Meert, K. L., Anand, K. J., Zimmerman, J., Newth, C. J., Harrison, R., Burr, J., Willson, D. F., and Nicholson, C. The randomized comparative pediatric critical illness stress-induced immune suppres
  20. Chungchunlam, S. M., Moughan, P. J., Henare, S. J., and Ganesh, S. Effect of time of consumption of preloads on measures of satiety in healthy normal weight women. Appetite 2012;59(2):281-288. PubMed
  21. Rencuzogullari I, Börekçi A, Karakoyun S, et al. Coronary thrombosis in three coronary arteries due to whey protein. Am J Emerg Med. 2017;35(4):664.e3-664.e4. PubMed
  22. Silverberg NB. Whey protein precipitating moderate to severe acne flares in 5 teenaged athletes. Case Reports Cutis. 2012;90(2):70-2.
  23. Simonart T. Acne and whey protein supplementation among bodybuilders. Dermatology. 2012;225(3):256-8. PubMed
  24. Pontes TC, Costa Fernandes Filho GM, Pereira Trindade AS, Sobral Filho JF. Incidence of acne vulgaris in young adult users of protein-calorie supplements in the city of João Pessoa-PB. An Bras Dermatol. 2013;88(6):907-12.
  25. Adebamowo CA, Spiegelman D, Berkey CS, et al. Milk consumption and acne in teenaged boys. J Am Acad Dermatol. 2008 May;58(5):787-93. PubMed

See these in context on the Whey Protein monograph →

L-arginine 66 references
  1. Sapienza MA, Kharitonov SA, Horvath I, et al. Effect of inhaled L-arginine on exhaled nitric oxide in normal and asthmatic subjects. Thorax 1998;53:172-5.
  2. Clarkson P, Adams MR, Powe AJ, et al. Oral L-arginine improves endothelium-dependent dilation in hypercholesterolemic young adults. J Clin Invest 1996;97:1989-94. PubMed
  3. Tenenbaum A, Fisman EZ, Motro M. L-arginine: Rediscovery in progress. Cardiology 1998;90:153-9.
  4. Brittenden J, Park KGM, Heys SD, et al. L-Arginine stimulates host defenses in patients with breast cancer. Surgery 1994;115:205-12.
  5. Korting GE, Smith SD, Wheeler MA, et al. A randomized double-blind trial of oral L-arginine for treatment of interstitial cystitis. J Urol 1999;161:558-65. DOI
  6. Rector TS, Bank AJ, Mullen KA, et al. Randomized, double-blind, placebo-controlled study of supplemental oral L-arginine in patients with heart failure. Circulation 1996;93:2135-41.
  7. Siani A, Pagano E, Iacone R, et al. Blood pressure and metabolic changes during dietary L-arginine supplementation in humans. Am J Hypertens 2000;13:547-51. PubMed
  8. Cheng JW, Balwin SN. L-arginine in the management of cardiovascular diseases. Ann Pharmacother 2001;35:755-64. PubMed
  9. Wallace AW, Tom WL. Interaction of L-arginine and phosphodiesterase inhibitors in vasodilation of the porcine internal mammary artery. Anesth Analg 2000;90:840-6. DOI
  10. Huynh NT, Tayek JA. Oral arginine reduces systemic blood pressure in type 2 diabetes: its potential role in nitric oxide generation. J Am Coll Nutr 2002;21:422-7.. PubMed
  11. Staff AC, Berge L, Haugen G, et al. Dietary supplementation with L-arginine or placebo in women with pre-eclampsia. Acta Obstet Gynecol Scand 2004;83:103-7.
  12. Resnick DJ, Softness B, Murphy AR, et al. Case report of an anaphylactoid reaction to arginine. Ann Allergy Asthma Immunol 2002;88:67-8. PubMed
  13. Anon. Arginine hydrochloride injection (marketed as R-Gene 10). FDA Drug Safety Newsletter 2009;2(2):16-18. Available at: www.fda.gov/Drugs/DrugSafety/DrugSafetyNewsletter/default.htm.
  14. Higashi Y, Oshima T, Sasaki S, et. al. Angiotensin-converting enzyme inhibition, but not calcium antagonism, improves a response of the renal vasculature to L-arginine in patients with essential hypertension. Hypertension. 1998 Jul;32(1):16-24.
  15. Facchinetti, F., Longo, M., Piccinini, F., Neri, I., and Volpe, A. L-arginine infusion reduces blood pressure in preeclamptic women through nitric oxide release. J Soc Gynecol.Investig. 1999;6(4):202-207. DOI
  16. de Gouw, H. W., Verbruggen, M. B., Twiss, I. M., and Sterk, P. J. Effect of oral L-arginine on airway hyperresponsiveness to histamine in asthma. Thorax 1999;54(11):1033-1035. PubMed
  17. Komers, R., Komersova, K., Kazdova, L., Ruzickova, J., and Pelikanova, T. Effect of ACE inhibition and angiotensin AT1 receptor blockade on renal and blood pressure response to L-arginine in humans. J Hypertens. 2000;18(1):51-59. PubMed
  18. Cartledge, J. J., Davies, A. M., and Eardley, I. A randomized double-blind placebo-controlled crossover trial of the efficacy of L-arginine in the treatment of interstitial cystitis. BJU.Int. 2000;85(4):421-426.
  19. Sozykin, A. V., Noeva, E. A., Balakhonova, T. V., Pogorelova, O. A., and Men'shikov, M. I. [Effect of L-arginine on platelet aggregation, endothelial function adn exercise tolerance in patients with stable angina pectoris]. Ter.Arkh. 2000;72(8):24-27.
  20. Nagaya, N., Uematsu, M., Oya, H., Sato, N., Sakamaki, F., Kyotani, S., Ueno, K., Nakanishi, N., Yamagishi, M., and Miyatake, K. Short-term oral administration of L-arginine improves hemodynamics and exercise capacity in patients with precapillary pulmona
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  22. Park, K. G., Heys, S. D., Blessing, K., Kelly, P., McNurlan, M. A., Eremin, O., and Garlick, P. J. Stimulation of human breast cancers by dietary L-arginine. Clin.Sci.(Lond) 1992;82(4):413-417.
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Ornithine 1 reference
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Collagen Peptides 2 references
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