Arjuna Capsules Ingredients & Drug Interactions
by Herbal Hills
What is this page for?
First and foremost: checking Arjuna Capsules against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Arjuna Capsules is a dietary supplement by Herbal Hills with 2 active ingredients. Its ingredients are commonly taken for heart health and circulation, digestive problems (constipation, diarrhea), cholesterol support.Based on those ingredients, 933 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Arjuna Bark Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Arjuna Capsules by Herbal Hills
Ask about any prescription or over-the-counter medication and we check it for interactions with Arjuna Capsules by Herbal Hills — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Arjuna Capsules by Herbal Hills
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Arjuna Capsules contains 3 active ingredients. The main one is arjuna bark extract, a traditional botanical ingredient.
The product also includes a tannin component and arjunic acid. These are delivered in veggie capsules with silicon dioxide (an anti-caking agent) as inactive ingredients.
Does it work?
Not established
The evidence we hold doesn't establish that arjuna is effective for the conditions it's traditionally used for. Its effectiveness for obesity, high cholesterol, high blood pressure, and angina is rated as insufficient reliable evidence to rate — meaning the research so far isn't robust enough for us to make a confident claim either way.
How safe is it?
Some data gaps
Arjuna bark extract is generally well tolerated in short-term studies, but we don't have solid data on long-term safety, and product quality varies widely. The safety data advises against use during pregnancy and while breastfeeding because there isn't enough information to know whether it's safe in those situations.
Meds to double-check
Moderate interaction found
Before you take this, check with your pharmacist if you're on blood thinners or antiplatelet drugs (like warfarin or clopidogrel), diabetes medications, omeprazole for heartburn, chlorzoxazone for muscle pain, or any drug that your liver breaks down — a very common situation. Arjuna bark extract can raise levels of many medications and increase bleeding risk.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and some safety-information gaps remain.
If you're interested in traditional heart-health or cholesterol supplements, this one has a long history of use — but the evidence for how well it actually works isn't established yet. If you take any medications that your liver metabolizes, blood thinners, diabetes drugs, or the specific medications mentioned in our med watch section, talk with your pharmacist before starting.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 18, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Arjuna Capsules, straight from the product label.
| Brand | Herbal Hills |
|---|---|
| Barcode (UPC) | 8904268859757 |
| Net contents | 120 Veggie Cap(s) |
| Market status | On market |
| Date entered into DSLD | Jul 18, 2023 |
| DSLD ID | 296403 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Halal |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Arjuna Capsules by Herbal Hills, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Arjuna Bark Extract | 250 mg | -- |
| Arjuna Bark Blend, Powder | 250 mg | -- |
| Tannins | 60 mg | -- |
| Arjunic Acid | 2.5 mg | -- |
Other ingredients: Veggie Capsule, Silicon Dioxide
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Directions For Use: As a dietary supplement take 1 capsule twice daily, preferably after meals. For better results it should be taken with warm water
Precautions
Warning: Pregnant or lactating women are advised to consume herbal products under the advice of the healthcare practitioner.
Keep out of reach of children.
Do not use if pouch is broken. Please consult an expert before use.
Storage
Storage: Store in a cool dry place away from direct sunlight.
Formulation
Being natural product, color may vary over time as well as from batch to batch however effectiveness remains same.
Country of Origin: India
FDA Disclaimer Statement
This product is not intended to diagnose, treat, cure or prevent any disease.
Brand IP Statement(s)
Herbal Hills Back to Nature
General Statements
Neutral Code: MH/PD/AYU/002/10
Contents based on standard Raw Material as per traditional text
Seals/Symbols
QA ICS JAS-ANZ Halal India www.Halalindia.com HIW21081110 GMP Good Manufacturing Practice
Formula
Halal India www.Halalindia.com HIW21081110
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Arjuna Capsules by Herbal Hills label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Arjuna Capsules by Herbal Hills
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Veggie Capsule(s) Dosage formCapsule Servings per container120 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Arjuna Bark Extract
Interacts with933 drugs
Terminalia is a group of traditional Ayurvedic tree species (most notably Terminalia arjuna) used for heart, digestive, and general wellness purposes....
Arjuna Bark Extract monograph & interactionsArjuna Bark Blend, Powder
Interacts with933 drugs
Terminalia is a group of traditional Ayurvedic tree species (most notably Terminalia arjuna) used for heart, digestive, and general wellness purposes....
Arjuna Bark Blend, Powder monograph & interactions- › Tannins
- › Arjunic Acid
Other (inactive) ingredients: Veggie Capsule, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.
Arjuna Capsules by Herbal Hills Drug Interactions
HelloPharmacist Interaction Report
Arjuna Capsules by Herbal Hills contains arjuna bark extract, which has documented interactions with several medication types.
The most serious concern involves how it affects your liver's ability to metabolize drugs. Arjuna bark extract inhibits three major enzyme systems (CYP2D6, CYP2C9, and CYP3A4), which means it can increase blood levels and effects of medications that rely on these pathways — potentially causing unwanted side effects.
Altogether, these interactions span 922 individual medications.
Read the full breakdown — every affected drug type, severity by severity
Modeately concerning interactions also exist with blood thinners (anticoagulants and antiplatelet drugs): arjuna bark extract may increase bleeding risk because it shows blood-thinning properties of its own. Additionally, the product may affect blood sugar control if you take diabetes medications, and it may increase levels of omeprazole (a heartburn drug) and chlorzoxazone (a muscle relaxer).
We could not check two other ingredients in this product — tannins and arjunic acid — because we hold no interaction data for them. Please check your exact medications with the search tool below before starting this supplement.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Arjuna Capsules?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Arjuna Capsules interact with 933 drugs. Click any drug to see the details.
1 of the 2 ingredients in Arjuna Capsules interact with drugs. Each result below shows which ingredient is responsible. Arjuna Bark Extract
BedaquilineSirturo
How Bedaquiline interacts with Arjuna Capsules — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Blend, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna Bark Blend, Powder + Bedaquiline interactionBelladonna Alkaloids, Chlorpheniramine, Phenylephrine, PhenylpropanolamineRespa ARM
How Belladonna Alkaloids, Chlorpheniramine, Phenylephrine, Phenylpropanolamine interacts with Arjuna Capsules — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Blend, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna Bark Blend, Powder + Belladonna Alkaloids, Chlorpheniramine, Phenylephrine, Phenylpropanolamine interactionBelladonna Alkaloids, Ergotamine Tartrate, PhenobarbitalBel Tabs, Bellamine-S, Bellaphen-S, Duragal S, Phenarbal S, Spastrin
How Belladonna Alkaloids, Ergotamine Tartrate, Phenobarbital interacts with Arjuna Capsules — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Blend, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna Bark Blend, Powder + Belladonna Alkaloids, Ergotamine Tartrate, Phenobarbital interactionBelladonna, Caffeine, Ergotamine, PentobarbitalMicomp PB
How Belladonna, Caffeine, Ergotamine, Pentobarbital interacts with Arjuna Capsules — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Blend, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna Bark Blend, Powder + Belladonna, Caffeine, Ergotamine, Pentobarbital interactionBelladonna, Ergotamine Tartrate, Phenobarbital
How Belladonna, Ergotamine Tartrate, Phenobarbital interacts with Arjuna Capsules — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Blend, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna Bark Blend, Powder + Belladonna, Ergotamine Tartrate, Phenobarbital interactionBelladonna, Ergotamine, PhenobarbitalBellergal-S
How Belladonna, Ergotamine, Phenobarbital interacts with Arjuna Capsules — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Blend, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna Bark Blend, Powder + Belladonna, Ergotamine, Phenobarbital interactionBellafoline, Caffeine, Ergotamine Tartrate, PentobarbitalCafergot PB
How Bellafoline, Caffeine, Ergotamine Tartrate, Pentobarbital interacts with Arjuna Capsules — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Blend, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna Bark Blend, Powder + Bellafoline, Caffeine, Ergotamine Tartrate, Pentobarbital interactionBelumosudil MesylateRezurock
How Belumosudil Mesylate interacts with Arjuna Capsules — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Blend, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna Bark Blend, Powder + Belumosudil Mesylate interactionBenzhydrocodone, AcetaminophenApadaz
How Benzhydrocodone, Acetaminophen interacts with Arjuna Capsules — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Blend, PowderCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna Bark Blend, Powder + Benzhydrocodone, Acetaminophen interactionBepridilVascor
How Bepridil interacts with Arjuna Capsules — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Blend, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna Bark Blend, Powder + Bepridil interactionBetrixabanBevyxxa
How Betrixaban interacts with Arjuna Capsules — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Blend, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Terminalia arjuna with anticoagulant or antiplatelet drugs may increase the risk of bleeding in some patients.
Read the full Arjuna Bark Blend, Powder + Betrixaban interactionBexaroteneTargretin
How Bexarotene interacts with Arjuna Capsules — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Blend, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna Bark Blend, Powder + Bexarotene interactionBictegravir, Emtricitabine, Tenofovir AlafenamideBiktarvy
How Bictegravir, Emtricitabine, Tenofovir Alafenamide interacts with Arjuna Capsules — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Blend, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna Bark Blend, Powder + Bictegravir, Emtricitabine, Tenofovir Alafenamide interactionBisoprololZebeta
How Bisoprolol interacts with Arjuna Capsules — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Blend, PowderCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Arjuna Bark Blend, Powder + Bisoprolol interactionBisoprolol, HydrochlorothiazideZiac
How Bisoprolol, Hydrochlorothiazide interacts with Arjuna Capsules — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Blend, PowderCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Arjuna Bark Blend, Powder + Bisoprolol, Hydrochlorothiazide interactionBivalirudinAngiomax, Angiomax Rtu, Angiox
How Bivalirudin interacts with Arjuna Capsules — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Blend, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Terminalia arjuna with anticoagulant or antiplatelet drugs may increase the risk of bleeding in some patients.
Read the full Arjuna Bark Blend, Powder + Bivalirudin interactionBoceprevirVictrelis
How Boceprevir interacts with Arjuna Capsules — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Blend, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna Bark Blend, Powder + Boceprevir interactionBosentanTracleer
How Bosentan interacts with Arjuna Capsules — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Blend, PowderCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2c9 (cyp2c9) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna Bark Blend, Powder + Bosentan interactionBosutinibBosulif
How Bosutinib interacts with Arjuna Capsules — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Blend, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna Bark Blend, Powder + Bosutinib interactionBrentuximab VedotinAdcetris
How Brentuximab Vedotin interacts with Arjuna Capsules — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Blend, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna Bark Blend, Powder + Brentuximab Vedotin interactionBrexpiprazoleRexulti
How Brexpiprazole interacts with Arjuna Capsules — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Blend, PowderCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna Bark Blend, Powder + Brexpiprazole interactionBrigatinibAlunbrig
How Brigatinib interacts with Arjuna Capsules — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Blend, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna Bark Blend, Powder + Brigatinib interactionBromfenac SodiumBromsite, Prolensa
How Bromfenac Sodium interacts with Arjuna Capsules — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Blend, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Terminalia arjuna with anticoagulant or antiplatelet drugs may increase the risk of bleeding in some patients.
Read the full Arjuna Bark Blend, Powder + Bromfenac Sodium interactionBromocriptineParlodel
How Bromocriptine interacts with Arjuna Capsules — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Blend, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna Bark Blend, Powder + Bromocriptine interactionBrompheniramine, Dextromethorphan, PhenylephrineDimetapp DM
How Brompheniramine, Dextromethorphan, Phenylephrine interacts with Arjuna Capsules — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Blend, PowderCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Arjuna Bark Blend, Powder + Brompheniramine, Dextromethorphan, Phenylephrine interactionBudenosidePulmicort Flexhaler, Pulmicort Turbuhaler
How Budenoside interacts with Arjuna Capsules — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Blend, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna Bark Blend, Powder + Budenoside interactionBudesonideEntocort EC, Eohilia, Pulmicort, Tarpeyo, Uceris
How Budesonide interacts with Arjuna Capsules — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Blend, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna Bark Blend, Powder + Budesonide interactionBudesonide, FormoterolSymbicort
How Budesonide, Formoterol interacts with Arjuna Capsules — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Blend, PowderCytochrome P450 2c9 (cyp2c9) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2C9 substrates.
Read the full Arjuna Bark Blend, Powder + Budesonide, Formoterol interactionBupivacaine, MeloxicamZynrelef Kit
How Bupivacaine, Meloxicam interacts with Arjuna Capsules — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Blend, PowderCytochrome P450 2c9 (cyp2c9) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2C9 substrates.
Read the full Arjuna Bark Blend, Powder + Bupivacaine, Meloxicam interactionBuprenorphineBrixadi, Butrans, Sublocade, Subutex
How Buprenorphine interacts with Arjuna Capsules — through 1 ingredient. Tap an ingredient for the detail:
Arjuna Bark Blend, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna Bark Blend, Powder + Buprenorphine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Arjuna Capsules with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Arjuna Bark Extract
Anticoagulant/Antiplatelet Drugs
Theoretically, concomitant use of Terminalia arjuna with anticoagulant or antiplatelet drugs may increase the risk of bleeding in some patients.
In vitro, Terminalia arjuna bark extract inhibits platelet aggregation, decreases platelet activation, and shows antithrombotic properties.
Antidiabetes Drugs
Theoretically, concomitant use of Terminalia bellirica or Terminalia chebula with antidiabetes drugs could affect blood sugar control and increase the risk of hypoglycemia.
Animal and in vitro research shows that Terminalia bellirica and Terminalia chebula fruit and seed extract have hypoglycemic effects.
Chlorzoxazone (Parafon Forte, Paraflex)
Theoretically, use of Terminalia chebula may increase the risk of adverse effects from chlorzoxazone.
Animal research shows that enteral administration of Terminalia chebula for 15 days prior to administration of chlorzoxazone increases blood levels of chlorzoxazone and decreases chlorzoxazone clearance. It is speculated that Terminalia chebula reduces the metabolism of chlorzoxazone by inhibiting cytochrome P450 2E1.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2C9 substrates.
In vitro research shows that Terminalia arjuna extract inhibits CYP2C9 enzymes and reduces CYP2C9 substrate metabolism.
Cytochrome P450 2D6 (Cyp2D6) Substrates
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
In vitro research shows that Terminalia arjuna extract inhibits CYP2D6 enzymes and reduces CYP2D6 substrate metabolism.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that Terminalia arjuna extract inhibits CYP3A4 enzymes and reduces CYP3A4 substrate metabolism.
Omeprazole (Prilosec)
Theoretically, use of Terminalia chebula may increase the risk of adverse effects from omeprazole.
Animal research shows that enteral administration of Terminalia chebula for 15 days prior to administration of omeprazole increases blood levels of omeprazole and decreases omeprazole clearance. It is speculated that Terminalia chebula reduces the metabolism of omeprazole by inhibiting cytochrome P450 2C19.
Brand information
Manufacturer and brand details for Arjuna Capsules, from the product label.
Arjuna Capsules by Herbal Hills: Common Questions
Does Arjuna Capsules by Herbal Hills interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is arjuna safe to take during pregnancy or while breastfeeding?
Does this product actually work for heart health or cholesterol?
What's in this product besides the active ingredient?
Should I be concerned about long-term use?
I'm taking a muscle relaxer (chlorzoxazone) for a sore back. Can I take this?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Arjuna Capsules is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Arjuna Capsules’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Arjuna Capsules's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 9 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Terminalia 9 references
- Sabu, M. C. and Kuttan, R. Anti-diabetic activity of medicinal plants and its relationship with their antioxidant property. J Ethnopharmacol. 2002;81(2):155-160. PubMed
- Rao, N. K. and Nammi, S. Antidiabetic and renoprotective effects of the chloroform extract of Terminalia chebula Retz. seeds in streptozotocin-induced diabetic rats. BMC.Complement Altern.Med 2006;6:17. PubMed
- Murali, Y. K., Anand, P., Tandon, V., Singh, R., Chandra, R., and Murthy, P. S. Long-term effects of Terminalia chebula Retz. on hyperglycemia and associated hyperlipidemia, tissue glycogen content and in vitro release of insulin in streptozotocin induced
- Senthilkumar, G. P. and Subramanian, S. Evaluation of antioxidant potential of Terminalia chebula fruits studies in streptozotocin-induced diabetic rats. Pharmaceutical Biology (Netherlands) 2007;45:511-518.
- Malik N, Dhawan V, Bahl A, Kaul D. Inihbitory effects of Terminalia arjuna on platelet activation in vitro in healthy subjects and patients with coronary artery disease. Platelets. 2009;20(3):183-1190.
- Varghese A, Savai J, Pandita N, Gaud RS. In vitro modulatory effects of Terminalia arjuna, arjunic acid, arjunetin, and arjungenin on CYP3A4, CYP2D6, and CYP2C9 enzyme activity in human liver microsomes. Toxicology Reports. 2015(2):806-16. PubMed
- Wu G, Dong Z, Dong J, et al. Effects of mongolian medicine Terminalia chebula Retz. on 6 CYP450 enzymes in rats. Int J Clin Exp Pathol 2020;13(12):3128-3138.
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