Interactions on record — worth a quick check against your medications. Based on 3 of 7 ingredients. Check your meds →
Dietary supplement

Atomic 7 Way Out Watermelon Ingredients & Drug Interactions

by Universal

Atomic 7 Way Out Watermelon label
See full label image
Powder Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Atomic 7 Way Out Watermelon against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Atomic 7 Way Out Watermelon is a dietary supplement by Universal with 7 active ingredients. Its ingredients are commonly taken for muscle recovery and sports performance, gut health and 'leaky gut', recovery from severe illness or injury.Based on those ingredients, 250 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Vitamin B6, L-Taurine, L-Glutamine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Atomic 7 Way Out Watermelon by Universal

Ask about any prescription or over-the-counter medication and we check it for interactions with Atomic 7 Way Out Watermelon by Universal — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Atomic 7 Way Out Watermelon by Universal

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 7 of its 7 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This 7-ingredient powder contains three branched-chain amino acids—L-Leucine, L-Isoleucine, and L-Valine—along with L-Glutamine, Vitamin B6, L-Taurine, and Citrulline Malate. Amino acids are the building blocks your body uses to make and repair muscle and other tissues.

Citrulline Malate is a compound that may support blood flow and workout performance. The product also contains inactive ingredients including citric acid for flavor and texture, artificial watermelon flavor, and sweeteners.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Strong

Strong clinical evidence supports its ingredients for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Sickle cell disease — rated "Effective" (Glutamine) (Natural Medicines).
  • On file: Sideroblastic anemia — rated "Effective" (Vitamin B6) (Natural Medicines).
  • On file: Pyridoxine-dependent epilepsy — rated "Effective" (Vitamin B6) (Natural Medicines).
  • On file: Vitamin B6 deficiency — rated "Effective" (Vitamin B6) (Natural Medicines).
  • On file: Hyperhomocysteinemia — rated "Likely Effective" (Vitamin B6) (Natural Medicines).

In our data, L-Glutamine is rated Effective for sickle cell disease and Possibly Effective for HIV/AIDS-related wasting, postoperative recovery, and recovery from critical illness or trauma. Vitamin B6 is rated Effective for sideroblastic anemia and vitamin B6 deficiency, Likely Effective for high homocysteine levels, and Possibly Effective for pregnancy-related nausea and vomiting.

L-Taurine is rated Possibly Effective for hepatitis and heart failure, and Possibly Ineffective for weight loss. We hold no effectiveness ratings for the branched-chain amino acids or Citrulline Malate in this product.

The evidence, ingredient by ingredient Glutamine Vitamin B6 Taurine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-Glutamine is generally well tolerated but can cause gastrointestinal side effects like bloating, constipation, nausea, diarrhea, and stomach pain—especially at higher doses. People with kidney or liver disease should use it only under medical supervision, and there isn't enough safety data to recommend supplemental doses while breastfeeding unless your doctor says otherwise.

Vitamin B6 is well tolerated at doses under 100 mg daily, but high doses over time can damage nerves (a condition called sensory neuropathy), and high doses may also cause headache or upset stomach. L-Taurine is generally well tolerated short-term in healthy adults but can cause constipation, diarrhea, or indigestion; long-term safety is less certain.

People with a history of allergies to sulfonamides or sulfites should be cautious, as one case of an allergic reaction to taurine has been reported. Both L-Glutamine and L-Taurine are rated Likely Safe in pregnancy and lactation.

Side effects, ingredient by ingredient Glutamine Vitamin B6 Taurine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Glutamine, Vitamin B6, Taurine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: seizure medications; lithium; Parkinson's medications.
  • For scale: 250 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check if you're on anticonvulsant drugs (for seizures)—glutamine may reduce their effectiveness. Moderate interactions are possible with blood pressure medications, lithium, amiodarone, or the seizure drugs phenobarbital and phenytoin due to vitamin B6 content.

If you take levodopa without carbidopa, vitamin B6 may interfere with it. If none of these apply to you, no interactions are documented for the other ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

This product is marketed for muscle support and workout performance using amino acids and related compounds. If you take any anticonvulsants, blood pressure medications, lithium, amiodarone, phenobarbital, phenytoin, or levodopa alone, check your exact medications with our tool before starting.

People with kidney or liver disease should talk to their doctor first. For most healthy adults with no medications, it's generally well tolerated, but GI side effects like bloating or stomach upset are possible.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 7 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 24, 2016.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Atomic 7 Way Out Watermelon, straight from the product label.

Brand Universal
Barcode (UPC) 039442052414
Net contents 384 Gram(s)
Market status On market
Date entered into DSLD Aug 24, 2016
DSLD ID 64113
Product type Other Combinations
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Atomic 7 Way Out Watermelon by Universal, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
12.78 Gram(s)
Maximum serving Sizes:
12.78 Gram(s)
Servings per container
30
UPC/BARCODE
039442052414
IngredientAmount% DV
L-Glutamine2 Gram(s)--
Vitamin B610 mg500%
L-Leucine4 Gram(s)--
L-Isoleucine2 Gram(s)--
L-Valine2 Gram(s)--
L-Taurine500 mg--
Citrulline Malate1 Gram(s)--

Other ingredients: Citric Acid, artificial Watermelon flavor, Acesulfame K, Sucralose, Red #40 Lake, Pyridoxine Hydrochloride

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Made in a GMP facility on equipment that processes milk, soy, egg, peanuts, tree nuts, fish, shellfish, and wheat.

Warning: This product is not for use by anyone under the age of 18.

Do not take this if you have or are at risk for any medical condition or disease.

Please consult with a physician before using this product, especially if you are using any prescription drug, over-the-counter medication, or supplements.

Immediately discontinue use if any side effects occur. California Residents Proposition 65 Warning: This product contains a substance known to the State of California to cause birth defects or other reproductive harm.

Keep out of reach of children.

Athletes should consult with their sanctioning authority before use. Do not exceed recommended dose.

Suggested/Recommended/Usage/Directions

Dosage: As a dietary supplement, mix 1 scoop of Atomic 7 with 8-12 ounces of your favorite cold beverage. Add powder after the liquid is already in the shaker or cup. For best results take before and after workout.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General Statements

Made proudly in the U.S.A.

EAC

Enhance recovery ~ Maximize workout performance ~ Improve endurance

WHO WE ARE Universal Nutrition has been providing cutting edge and staple nutritional supplements to bodybuilders and hard training athletes the world over since 1977. As time passes, certain ideals never go out of style. Honesty. Integrity. Respect. These are the values we uphold and are the bedrock upon which we built our business.

These potent ergogenic aids are further enhanced with vitamin B6, allowing absorption. HOW WE BACK IT UP What is on the label is in the bottle and what is in the bottle will help you reach your goals. We believe it and proudly stand behind every product we manufacture. Our word is our bond.

Plant #3001104580

Brand IP Statement(s)

2015 Universal Nutrition

WHAT IT IS Atomic 7 is a targeted and enhanced BCAA performance supplement, Atomic 7 combines the benefits of a scientifically proven 2:1:1 ratio of BCAA along with key performance ingredients such as citrulline malate, L-glutamine and L-taurine.

FDA Statement of Identity

Dietary Supplement

General

B1115-G-32877

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Atomic 7 Way Out Watermelon by Universal label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Atomic 7 Way Out Watermelon label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Atomic 7 Way Out Watermelon by Universal

These are the 7 active ingredients this product is made of. Select any to open its full monograph.

Serving size12.78 Gram(s) Dosage formPowder Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

L-Glutamine

Interacts with
50 drugs
2 Gram(s) per serving

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle c...

L-Glutamine monograph & interactions

Vitamin B6

Interacts with
210 drugs
10 mg per serving

Vitamin B6 (pyridoxine) is an essential water-soluble vitamin that your body needs for metabolism, brain function, and making red blood cells. It is b...

Vitamin B6 monograph & interactions

L-Leucine

4 Gram(s) per serving

L-Isoleucine

2 Gram(s) per serving

L-Valine

2 Gram(s) per serving

L-Taurine

Interacts with
173 drugs
500 mg per serving

Taurine is an amino acid your body makes naturally and that you also get from animal foods. It is widely used in energy drinks and sports supplements,...

L-Taurine monograph & interactions

Citrulline Malate

1 Gram(s) per serving

Other (inactive) ingredients: Citric Acid, Artificial Watermelon flavor, Acesulfame K, Sucralose, Red #40 Lake, Pyridoxine Hydrochloride. These complete the product’s ingredient list but are not active constituents.

Interaction report

Atomic 7 Way Out Watermelon by Universal Drug Interactions

Want to check YOUR meds against Atomic 7 Way Out Watermelon?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
250Drugs
245 Moderate 5 Minor

Ingredients driving the most interactions

Vitamin B6 210
L-Taurine 173
L-Glutamine 50

Individual Drug Interactions

The ingredients in Atomic 7 Way Out Watermelon interact with 250 drugs. Click any drug to see the details.

3 of the 7 ingredients in Atomic 7 Way Out Watermelon interact with drugs. Each result below shows which ingredient is responsible. Vitamin B6 L-Taurine L-Glutamine

Each ingredient & the kinds of drugs it affects

For each ingredient in Atomic 7 Way Out Watermelon with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin B65 drug types · 210 drugs

Amiodarone (Cordarone)

Theoretically, vitamin B6 might increase the photosensitivity caused by amiodarone.
Despite initial case reports suggesting that pyridoxine may have a protective effect against amiodarone-induced photosensitivity, preliminary clinical research suggests that pyridoxine may actually exacerbate this adverse effect.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, vitamin B6 may have additive effects when used with antihypertensive drugs.
Research in hypertensive rats shows that vitamin B6 can decrease systolic blood pressure. Similarly, clinical research in patients with hypertension shows that taking high doses of vitamin B6 may reduce systolic and diastolic blood pressure, possibly by reducing plasma levels of epinephrine and norepinephrine.

Likelihood Possible Evidence B
Phenobarbital (Luminal)

High doses of vitamin B6 may reduce the levels and clinical effects of phenobarbital.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenobarbital, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenobarbital to avoid high doses of vitamin B6.

Likelihood Possible Evidence D
Phenytoin (Dilantin)

High doses of vitamin B6 may reduce the levels and clinical effects of phenytoin.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenytoin, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenytoin to avoid high doses of vitamin B6.

Likelihood Possible Evidence D
Levodopa

Vitamin B6 may increase the metabolism of levodopa when taken alone, but not when taken in conjunction with carbidopa.
Vitamin B6 (pyridoxine) enhances the metabolism of levodopa, reducing its clinical effects. However, this interaction does not occur when carbidopa is used concurrently with levodopa (Sinemet). Therefore, it is not likely to be a problem in most people.

Likelihood Unlikely Evidence D
Vitamin B6 full monograph & interactions

L-Taurine2 drug types · 173 drugs

Antihypertensive Drugs

Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.
Some clinical evidence suggests that taurine can reduce both systolic and diastolic blood pressure.

Likelihood Probable Evidence D
Lithium

Theoretically, taurine might reduce excretion and increase plasma levels of lithium.
Taurine is thought to have diuretic properties, which might reduce the excretion of lithium.

Likelihood Probable Evidence D
L-Taurine full monograph & interactions

L-Glutamine1 drug type · 50 drugs

Anticonvulsants

Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Glutamine is metabolized to the excitatory neurotransmitter glutamate. Glutamate might have antagonistic effects with anticonvulsant drugs. However, this interaction has not yet been reported in humans.

Likelihood Possible Evidence D
L-Glutamine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Atomic 7 Way Out Watermelon, from the product label.

Universal

See all Universal products
Name
Universal Nutrition
City
New Brunswick
State
New Jersey
ZipCode
08901
Phone Number
800-872-0101
Web Address
www.UniversalUSA.com
Pharmacist Counseling Corner

Atomic 7 Way Out Watermelon by Universal: Common Questions

Does Atomic 7 Way Out Watermelon by Universal interact with any medications?
Yes. Based on its ingredients, Atomic 7 Way Out Watermelon has a known interaction with 250 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Atomic 7 Way Out Watermelon contains 7 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
The two main active ingredients we have data for—L-Glutamine and L-Taurine—are both rated Likely Safe in pregnancy and lactation. Vitamin B6 is Likely Safe in pregnancy but rated Possibly Unsafe in pregnancy in some studies, so talk to your doctor or midwife before using this product while pregnant or breastfeeding to make sure it's right for you.
What side effects might I get from L-Glutamine?
Most commonly, belching, bloating, constipation, diarrhea, nausea, stomach pain, and headache. These are usually mild. People with kidney or liver disease should only use it under medical supervision.
Is Vitamin B6 safe at the dose in this product?
Vitamin B6 is well tolerated below 100 mg daily. At very high doses over time (especially above 1000 mg daily), it can cause nerve damage. This product contains B6, but we'd need to see the exact dose on the label to say whether it's in the safe range for you. If you're taking other B6 supplements or have any nerve symptoms, check with your pharmacist.
What are the branched-chain amino acids for?
L-Leucine, L-Isoleucine, and L-Valine are amino acids your body uses to build and repair muscle tissue. They're often used in fitness and recovery products, though we don't have effectiveness ratings for them in our data.
Can I take this with my seizure medication?
L-Glutamine in this product may theoretically work against anticonvulsant drugs and reduce how well they work. If you take any seizure medication, check your specific drugs with our tool and talk to your pharmacist or doctor before starting this supplement.
Does this product have any fillers?
Yes. Besides the seven active ingredients, it contains citric acid, artificial watermelon flavor, Acesulfame K, Sucralose, and Red #40 Lake as inactive ingredients.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Atomic 7 Way Out Watermelon is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Atomic 7 Way Out Watermelon label
Go deeper

The Full Monographs Behind Atomic 7 Way Out Watermelon’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Glutamine

Interacts with 50 drugs

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle cell disease complications, but for most...

Read the full Glutamine monograph → Herb & supplement monograph

Vitamin B6

Interacts with 210 drugs

Vitamin B6 (pyridoxine) is an essential water-soluble vitamin that your body needs for metabolism, brain function, and making red blood cells. It is best known for helping with pregnancy-rel...

Read the full Vitamin B6 monograph → Herb & supplement monograph

Taurine

Interacts with 173 drugs

Taurine is an amino acid your body makes naturally and that you also get from animal foods. It is widely used in energy drinks and sports supplements, and short-term use appears generally sa...

Read the full Taurine monograph →
Sources

Sources & How We Checked

Atomic 7 Way Out Watermelon's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 64 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutamine 11 references
  1. Miller AL. Therapeutic considerations of L-glutamine: a review of the literature. Altern Med Rev 1999;4:239-48..
  2. Bozzetti F, Biganzoli L, Gavazzi C, et al. Glutamine supplementation in cancer patients receiving chemotherapy: a double-blind randomized study. Nutrition 1997;13:748-51.. PubMed
  3. Mebane AH. L-Glutamine and mania. Am J Psychiatry 984;141:1302-3.
  4. Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000;130:1007S-15S.. PubMed
  5. Garlick PJ. Assessment of the safety of glutamine and other amino acids. J Nutr 2001;131:2556S-61S.. PubMed
  6. Chapman AG. Glutamate and epilepsy. J Nutr 2000;130:1043S-5S.. PubMed
  7. Ziegler TR. Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy. J Nutr 2001;131:2578S-84S.. PubMed
  8. Laviano A, Molfino A, Lacaria MT, Canelli A, De Leo S, Preziosa I, Rossi Fanelli F. Glutamine supplementation favors weight loss in nondieting obese female patients. A pilot study. Eur J Clin Nutr. 2014 Nov;68(11):1264-6. PubMed
  9. Endari (l-glutamine) [package insert]. Torrance, CA: Emmaus Medical,Inc; 2017.
  10. Niihara Y, Miller ST, Kanter J, et al. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. N Engl J Med 2018;379(3):226-35. doi: 10.1056/NEJMoa1715971.
  11. Ogden HB, Child RB, Fallowfield JL, et al. Gastrointestinal Tolerance of Low, Medium and High Dose Acute Oral l-Glutamine Supplementation in Healthy Adults: A Pilot Study. Nutrients. 2020;12(10):2953. PubMed

See these in context on the Glutamine monograph →

Vitamin B6 32 references
  1. Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
  2. Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
  3. Geerling BJ, Dagnelie PC, Badart-Smook A, et al. Diet as a risk factor for the development of ulcerative colitis. Am J Gastroenterol 2000;95:1008-13. PubMed
  4. South M. Neonatal seizures after pyridoxine use -- reply. Lancet 1999;354:2083. PubMed
  5. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  6. Baxter P, Aicardi J. Neonatal seizures after pyridoxine use. Lancet 1999;354:2082-3. PubMed
  7. Bendich A, Cohen M. Vitamin B6 safety issues. Ann N Y Acad Sci 1990;585:321-30.
  8. Schaumburg H, Kaplan J, Windebank A. Sensory neuropathy from pyridoxine abuse. A new megavitamin syndrome. N Engl J Med 1983;309:445-8. PubMed
  9. Gordon N. Pyridoxine dependency: an update. Dev Med Child Neurol 1997;39:63-5. PubMed
  10. Lewis PJ. Pain in the hand and wrist. Pyridoxine supplements may help patients with carpal tunnel syndrome. BMJ 1995;310:1534. PubMed
  11. Kaufman G. Pyridoxine against amiodarone-induced photosensitivity (letter). Lancet 1984;1:51-2. PubMed
  12. Mulrow JP, Mulrow CD, McKenna WJ. Pyridoxine and amiodarone-induced photosensitivity. Ann Intern Med 1985;103:68-9. PubMed
  13. Kawada A, Kashima A, Shiraishi H, et al. Pyridoxine-induced photosensitivity and hypophosphatasia. Dermatology 2000;201:356-60.. PubMed
  14. Vasile A, Goldberg R, Kornberg B. Pyridoxine toxicity: report of a case. J Am Osteopath Assoc 1984;83:790-1. DOI
  15. Hansson O, Sillanpaa M. Pyridoxine and serum concentration of phenytoin and phenobarbitone. Lancet 1976;1:256. DOI
  16. Jansen T, Romiti R, Kreuter A, Altmeyer P. Rosacea fulminans triggered by high-dose vitamins B6 and B12. J Eur Acad Dermatol Venereol 2001;15:484-5..
  17. Chittumma P, Kaewkiattikun K, Wiriyasiriwach B. Comparison of the effectiveness of ginger and vitamin B6 for treatment of nausea and vomiting in early pregnancy: a randomized double-blind controlled trial. J Med Assoc Thai 2007;90:15-20.
  18. Hatzitolios, A., Iliadis, F., Katsiki, N., and Baltatzi, M. Is the anti-hypertensive effect of dietary supplements via aldehydes reduction evidence based? A systematic review. Clin Exp.Hypertens. 2008;30(7):628-639. PubMed
  19. Vasdev, S., Ford, C. A., Parai, S., Longerich, L., and Gadag, V. Dietary vitamin B6 supplementation attenuates hypertension in spontaneously hypertensive rats. Mol.Cell Biochem. 1999;200(1-2):155-162.
  20. de, Vogel S., Dindore, V., van, Engeland M., Goldbohm, R. A., van den Brandt, P. A., and Weijenberg, M. P. Dietary folate, methionine, riboflavin, and vitamin B-6 and risk of sporadic colorectal cancer. J Nutr 2008;138(12):2372-2378. PubMed
  21. Hagen, I., Nesheim, B. I., and Tuntland, T. No effect of vitamin B-6 against premenstrual tension. A controlled clinical study. Acta Obstet.Gynecol.Scand. 1985;64(8):667-670. PubMed
  22. Aybak, M., Sermet, A., Ayyildiz, M. O., and Karakilcik, A. Z. Effect of oral pyridoxine hydrochloride supplementation on arterial blood pressure in patients with essential hypertension. Arzneimittelforschung. 1995;45(12):1271-1273.
  23. Lal, K. J., Dakshinamurti, K., and Thliveris, J. The effect of vitamin B6 on the systolic blood pressure of rats in various animal models of hypertension. J Hypertens. 1996;14(3):355-363. PubMed
  24. Lauritzen CH, Reuter HD, Repges R, Bohnert K, and Schmidt U. Treatment of premenstrual tension syndrome with Vitex agnus castus. Controlled, double-blind study versus pyridoxine. Phytomed 1997;4(3):183-189. PubMed
  25. Fonseca VA, Lavery LA, Thethi TK, et al. Metanx in type 2 diabetes with peripheral neuropathy: A randomized trial. Am J Med 2013;126(2):141-9. PubMed
  26. Hankey GJ, Eikelboom JW, Yi Q, et al. Treatment with B vitamins and incidence of cancer in patients with previous stroke or transient ischemic attack: Results of a randomized placebo-controlled trial. Stroke 2012;43(6):1572-7. PubMed
  27. Hoyer-Kuhn H, Kohbrok S, Volland R, Franklin J, Hero B, Beck BB, Hoppe B. Vitamin B6 in primary hyperoxaluria I: first prospective trial after 40 years of practice. Clin J Am Soc Nephrol. 2014 Mar;9(3):468-77. PubMed
  28. Mahmoud A, Tabassum S, Al Enazi S, et al. Amelioration of levetiracetam-induced behavioral side effects by pyridoxine. A randomized double blind controlled study. Pediatr Neurol 2021;119:15-21. PubMed
  29. Gupta M, Gallante B, Bamberger JN, et al. Prospective randomized evaluation of idiopathic hyperoxaluria treatments. J Endourol 2021;35(12):1844-1851. PubMed
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Taurine 21 references
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See these in context on the Taurine monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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