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Dietary supplement

Beet Root 500 mg Ingredients & Drug Interactions

by tnvitamins

Beet Root 500 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Beet Root 500 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Beet Root 500 mg is a dietary supplement by tnvitamins with 1 active ingredient. Its ingredients are commonly taken for high blood pressure, exercise and athletic performance, heart and circulation support.Based on those ingredients, 861 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Beet. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Beet Root 500 mg by tnvitamins

Ask about any prescription or over-the-counter medication and we check it for interactions with Beet Root 500 mg by tnvitamins — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Beet Root 500 mg by tnvitamins

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: beet at 500 mg per capsule. Beet is the whole plant used for its nutrient profile, including betanin, the pigment responsible for its red color and many of its effects on how your body processes drugs and manages blood vessel function.

The capsule also contains inactive ingredients—rice powder, gelatin, vegetable magnesium stearate, and silica—which are fillers, binders, and flow agents.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Beet's overall clinical evidence instead.

Moderate

Some clinical evidence supports Beet for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Athletic performance — rated "Possibly Effective" (Natural Medicines).
  • On file: Exercise-induced muscle soreness — rated "Possibly Effective" (Natural Medicines).

Beet has been studied for athletic performance and exercise-induced muscle soreness, where evidence suggests it's possibly effective. For COPD, the evidence points toward it being possibly ineffective.

For high cholesterol (dyslipidemia) and brain function (cognitive function), there isn't enough reliable data to rate it either way. If you're considering this for one of those uses, it's worth discussing what the current evidence does and doesn't show with your healthcare provider.

The evidence, ingredient by ingredient Beet

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Beet as a food is widely eaten and well tolerated by most adults. However, because concentrated supplements like this one lack robust safety data, we recommend using caution.

Short-term use appears to be well tolerated overall. The most common side effect is harmless red coloring of stools and urine—this is normal and not a sign of harm.

Beet juice has also been reported to cause black stools in some cases. Rare but serious effects from large amounts include low blood calcium (hypocalcemia) and kidney damage, which could happen if you take very high doses over time.

There isn't enough data on file about this product's safety during lactation.

Side effects, ingredient by ingredient Beet

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Beet.
  • The most serious interaction on file is rated Moderate.
  • For scale: 862 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check any drug broken down by CYP3A4 (a major liver enzyme)—this is Moderate severity and includes many heart, cholesterol, and immune medications. Also check drugs processed by CYP1A2, and any blood pressure medications you're on.

Use the search tool on this page with your exact medication names.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Beet root may help with athletic performance and exercise soreness, but it interacts with a very large number of medications—especially drugs your liver breaks down. If you take any prescription medications, you need to check them against this product before you start.

Talk to your pharmacist or doctor about whether it's right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Beet Root 500 mg, straight from the product label.

Brand tnvitamins
Barcode (UPC) 095234274303
Net contents 100 Capsule(s)
Market status On market
Date entered into DSLD Apr 23, 2020
DSLD ID 217823
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Beet Root 500 mg by tnvitamins, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
50
UPC/BARCODE
095234274303
IngredientAmount% DV
Beet1000 mg--

Other ingredients: Rice powder, Gelatin, Vegetable Magnesium Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Beta vulgaris

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement for adults, take two (2) capsules up to three times daily, preferably with a meal, or as directed by a health care professional.

Formulation

Free of: Gluten, wheat, yeast, milk, lactose, soy, artificial color, artificial flavor, artificial sweetener, preservatives. Non-GMO

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Caution: Pregnant or lactating women should consult a doctor before use.

If you are under medical supervision, please consult a doctor before use. Discontinue use and consult a doctor if any adverse reactions occur.

Keep out of reach of children.

General Statements

Reorder tnvitamins.com 800-645-4446

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Beet Root 500 mg by tnvitamins label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Beet Root 500 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Beet Root 500 mg by tnvitamins

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container50 Amounts shown are per serving.

Beet

Interacts with
861 drugs
1000 mg per serving

Beet, especially beetroot juice, is a nitrate-rich food that may modestly lower blood pressure and slightly improve exercise performance in some peopl...

Beet monograph & interactions

Other (inactive) ingredients: Rice powder, Gelatin, Vegetable Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Beet Root 500 mg by tnvitamins Drug Interactions

Want to check YOUR meds against Beet Root 500 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
861Drugs
643 Moderate 218 Minor

Ingredients driving the most interactions

Beet 861

Individual Drug Interactions

The ingredients in Beet Root 500 mg interact with 861 drugs. Click any drug to see the details.

1 of the 1 ingredient in Beet Root 500 mg interact with drugs. Each result below shows which ingredient is responsible. Beet

Each ingredient & the kinds of drugs it affects

For each ingredient in Beet Root 500 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Beet3 drug types · 861 drugs

Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, beet might increase the levels of CYP3A4 substrates.
In vitro research suggests that betanin, the major pigment in beet, competitively inhibits CYP3A4 in a dose-dependent manner similarly to strong CYP3A4 inhibitor ketoconazole.

Likelihood Possible Evidence D
Antihypertensive Drugs

Beet and beetroot contain nitrates, which can cause vasodilation, potentially leading to lower blood pressure. However, a study published in the European Journal of Clinical Nutrition using concentrated beetroot juice found no significant impact on blood pressure or heart rate in different age groups. Other small clinical studies suggest that while beet consumption might transiently lower blood pressure due to vessel dilation, there's no consistent evidence of a lasting effect. Overall, the theoretical risk of reduced blood pressure due to beet's nitrate content exists, but studies generally indicate a low and temporary impact rather than a sustained decrease.

Likelihood Possible Evidence A
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, beet might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research suggests that beet induces CYP1A2 enzymes.

Likelihood Possible Evidence D
Beet full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Beet Root 500 mg, from the product label.

tnvitamins

See all tnvitamins products
Name
TOTAL NUTRITION, INC.
City
FARMINGDALE
State
NY
ZipCode
11735
Phone Number
800-645-4446
Web Address
tnvitamins.com
Pharmacist Counseling Corner

Beet Root 500 mg by tnvitamins: Common Questions

Does Beet Root 500 mg by tnvitamins interact with any medications?
Yes. Based on its ingredients, Beet Root 500 mg has a known interaction with 861 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Beet Root 500 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will beet root help my athletic performance?
Beet has possibly effective evidence for athletic performance and for reducing exercise-induced muscle soreness. That means some research supports it, but the evidence isn't conclusive yet. Whether it'll help you personally is something to try and see, but don't count on it as a guaranteed boost.
Is red urine and red stools normal?
Yes—completely normal and harmless. Beet's pigment colors your urine and stool red. Some people also report black stools. Neither means anything's wrong.
Is this supplement safe if I eat beets normally?
Beet as a food is safe for most adults. A supplement concentrate is different—it lacks the safety data we have for whole beets. Our caution here is that we don't know as much about concentrated supplements, so use it carefully and stick to short-term use unless your doctor says otherwise.
Can I take this while breastfeeding?
We don't have safety data on file for beet during lactation. Talk to your doctor or pharmacist before taking it while breastfeeding so you can decide together what's best for you and your baby.
Will this raise or lower my blood pressure?
Beet contains nitrates that can relax blood vessels and potentially lower blood pressure. One study found no major change, but it's possible. If you're on blood pressure medication, you should check with your pharmacist before taking this, especially since the interaction is rated Minor.
What does betanin do?
Betanin is beet's main pigment—the compound that makes it red. It's also what interacts with how your liver breaks down certain medications. Lab work shows it can block the CYP3A4 enzyme, which could raise levels of drugs that depend on that enzyme to clear your body.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Beet Root 500 mg label
Go deeper

The Full Monographs Behind Beet Root 500 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Beet

Interacts with 861 drugs

Beet, especially beetroot juice, is a nitrate-rich food that may modestly lower blood pressure and slightly improve exercise performance in some people. It is generally safe as a food, but s...

Read the full Beet monograph →
Sources

Sources & How We Checked

Beet Root 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Beet 14 references
  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  2. Clifford T, Berntzen B, Davison GW, et al. Effects of beetroot juice on recovery of muscle function and performance between bouts of repeated sprint exercise. Nutrients 2016;8. pii: E506. PubMed
  3. Siervo M, Lara J, Ogbonmwan I, Mathers JC. Inorganic nitrate and beetroot juice supplementation reduces blood pressure in adults: a systematic review and meta-analysis. J Nutr 2013;143:818-26. PubMed
  4. Clifford T, Howatson G, West DJ, Stevenson EJ. Beetroot juice is more beneficial than sodium nitrate for attenuating muscle pain after strenuous eccentric-bias exercise. Appl Physiol Nutr Metab. 2017;42(11):1185-1191. PubMed
  5. Clifford T, Bell O, West DJ, Howatson G, Stevenson EJ. The effects of beetroot juice supplementation on indices of muscle damage following eccentric exercise. Eur J Appl Physiol. 2016;116(2):353-62. PubMed
  6. Wylie LJ, Kelly J, Bailey SJ, et al. Beetroot juice and exercise: pharmacodynamic and dose-response relationships. J Appl Physiol (1985). 2013;115(3):325-36. PubMed
  7. Garnacho-Castaño MV, Palau-Salvà G, Cuenca E, et al. Effects of a single dose of beetroot juice on cycling time trial performance at ventilatory thresholds intensity in male triathletes. J Int Soc Sports Nutr. 2018;15(1):49. PubMed
  8. Rasica L, Porcelli S, Marzorati M, et al. Ergogenic effects of beetroot juice supplementation during severe-intensity exercise in obese adolescents. Am J Physiol Regul Integr Comp Physiol. 2018;315(3):R453-R460. PubMed
  9. Henrohn D, Björkstrand K, Lundberg JO, et al. Effects of oral supplementation with nitrate-rich beetroot juice in patients with pulmonary arterial hypertension-results from BEET-PAH, an exploratory randomized, double-blind, placebo-controlled, crosso
  10. Serra-Payá N, Garnacho-Castaño MV, Sánchez-Nuño S, et al. The relationship between resistance exercise performance and ventilatory efficiency after beetroot juice intake in well-trained athletes. Nutrients 2021;13(4):1094. PubMed
  11. Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
  12. Hemmatinafar M, Zaremoayedi L, Koushkie Jahromi M, et al. Effect of Beetroot Juice Supplementation on Muscle Soreness and Performance Recovery after Exercise-Induced Muscle Damage in Female Volleyball Players. Nutrients 2023;15(17):3763. PubMed
  13. Lim SH, Bae S, Lee HS, Han HK, Choi CI. Effect of Betanin, the Major Pigment of Red Beetroot (Beta vulgaris L.), on the Activity of Recombinant Human Cytochrome P450 Enzymes. Pharmaceuticals (Basel) 2023;16(9):1224. PubMed
  14. Oscherwitz M, Tamayo RM, Heudebert A, Centor R. A Case of Pseudo-Hematochezia from Beet Supplement Ingestion. Am J Med 2023;136(9):e177-e178. PubMed

See these in context on the Beet monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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