Interactions on record — worth a quick check against your medications. Based on 1 of 5 ingredients. Check your meds →
Dietary supplement

Beta Plus Ingredients & Drug Interactions

by Biotics Research Corporation

Beta Plus label
See full label image
Tablet Or Pill Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Beta Plus against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Beta Plus is a dietary supplement by Biotics Research Corporation with 5 active ingredients. Its ingredients are commonly taken for high blood pressure, exercise and athletic performance, heart and circulation support.Based on those ingredients, 861 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are organic Beet concentrate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Beta Plus by Biotics Research Corporation

Ask about any prescription or over-the-counter medication and we check it for interactions with Beta Plus by Biotics Research Corporation — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Beta Plus by Biotics Research Corporation

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 5 of its 5 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Beta Plus contains five active ingredients. Organic beet concentrate is included for its potential role in exercise performance and muscle recovery.

The product also contains Superoxide Dismutase, Catalase, Ox Bile extract, and Pancrelipase—enzymes and bile compounds traditionally used in digestive support formulas. The tablet is made with inactive ingredients including cellulose, stearic acid, magnesium stearate, and food glaze.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Beet's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: antioxidant support with enzyme factors.
  • We looked for evidence on: Hypertension, Pregnancy-induced hypertension, Pulmonary hypertension, Coronary heart disease (CHD), Dyslipidemia, Hypertriglyceridemia — and 4 related terms.
  • The closest evidence on file: Beet is rated "Insufficient Reliable Evidence To Rate" for Coronary heart disease (CHD) (Natural Medicines).
  • Also on file: Beet is rated "Insufficient Reliable Evidence To Rate" for Liver disease, Dyslipidemia, Hypertension, Hypertriglyceridemia, and more.

For organic beet concentrate, the evidence shows it's possibly effective for athletic performance and exercise-induced muscle soreness. For chronic obstructive pulmonary disease (COPD), it's rated possibly ineffective.

For dyslipidemia (abnormal blood fat levels) and cognitive function, the evidence is insufficient to make a rating. We hold no effectiveness data for Superoxide Dismutase, Catalase, Ox Bile extract, or Pancrelipase in this product.

The evidence, ingredient by ingredient Beet

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Beet as a food is widely eaten and generally well tolerated in adults. However, the safety data for concentrated beet supplements is limited, so use caution.

The most common side effects from oral beet are red or black stools—the red coloring is harmless. Rare serious adverse effects include low blood calcium (hypocalcemia) and kidney damage when taken in large amounts.

One case reported black stools, nausea, and vomiting after taking beet pills in a patient on blood thinners. We hold no safety or pregnancy/breastfeeding data for the other four ingredients.

Side effects, ingredient by ingredient Beet

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Beet.
  • The most serious interaction on file is rated Moderate.
  • For scale: 862 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Beta Plus, double-check any drugs in these categories with your pharmacist: CYP3A4 substrates (Moderate severity—beet may raise their levels), blood pressure medications (Minor severity—beet's nitrates may lower pressure further), and CYP1A2 substrates (Minor severity—beet may decrease their effects). Altogether, these interactions span 850 individual medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

If you take medications processed by your liver—especially those metabolized by CYP3A4 or CYP1A2—or if you take blood pressure medications, check your specific drugs with the tool below before starting this product. The beet concentrate here is possibly helpful for athletic performance and exercise soreness, but concentrated supplements haven't been studied extensively.

Talk with your pharmacist about whether Beta Plus fits your regimen.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 24, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Beta Plus, straight from the product label.

Brand Biotics Research Corporation
Net contents 90 Tablet(s)
Market status On market
Date entered into DSLD May 24, 2013
DSLD ID 21477
Product type Other Combinations
Supplement form Tablet Or Pill
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Beta Plus by Biotics Research Corporation, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
IngredientAmount% DV
Superoxide Dismutase20 mcg--
Catalase20 mcg--
Ox Bile extract100 mg--
Pancrelipase50 mg--
organic Beet concentrate100 mg--

Other ingredients: Cellulose, Stearic Acid, Magnesium Stearate, Food Glaze

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Specially grown, biologically active vegetable culture containing naturally associated phytochemicals including polyphenolic compounds with SOD and catalase, dehydrated at low temperature to preserve associated enzyme factors.

Lot Number: 34455A Exp. Date: FEB 12

Sealed with an imprinted safety seal for your protection.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

RECOMMENDATION: One (1) tablet with each meal as a dietary supplement or as otherwise directed by a healthcare professional.

Precautions

KEEP OUT OF REACH OF CHILDREN

Storage

Store in a cool, dry area.

General

Rev. 9/09

Brand IP Statement(s)

(C) Copyright 2009

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Beta Plus by Biotics Research Corporation label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Beta Plus label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Beta Plus by Biotics Research Corporation

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Superoxide Dismutase

20 mcg per serving

Catalase

20 mcg per serving

Ox Bile extract

100 mg per serving

Pancrelipase

50 mg per serving Form: Porcine

Organic Beet concentrate

Interacts with
861 drugs
100 mg per serving

Beet, especially beetroot juice, is a nitrate-rich food that may modestly lower blood pressure and slightly improve exercise performance in some peopl...

Organic Beet concentrate monograph & interactions

Other (inactive) ingredients: Cellulose, Stearic Acid, Magnesium Stearate, Food Glaze. These complete the product’s ingredient list but are not active constituents.

Interaction report

Beta Plus by Biotics Research Corporation Drug Interactions

Want to check YOUR meds against Beta Plus?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
861Drugs
643 Moderate 218 Minor

Ingredients driving the most interactions

organic Beet concentrate 861

Individual Drug Interactions

The ingredients in Beta Plus interact with 861 drugs. Click any drug to see the details.

1 of the 5 ingredients in Beta Plus interact with drugs. Each result below shows which ingredient is responsible. organic Beet concentrate

Each ingredient & the kinds of drugs it affects

For each ingredient in Beta Plus with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

organic Beet concentrate3 drug types · 861 drugs

Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, beet might increase the levels of CYP3A4 substrates.
In vitro research suggests that betanin, the major pigment in beet, competitively inhibits CYP3A4 in a dose-dependent manner similarly to strong CYP3A4 inhibitor ketoconazole.

Likelihood Possible Evidence D
Antihypertensive Drugs

Beet and beetroot contain nitrates, which can cause vasodilation, potentially leading to lower blood pressure. However, a study published in the European Journal of Clinical Nutrition using concentrated beetroot juice found no significant impact on blood pressure or heart rate in different age groups. Other small clinical studies suggest that while beet consumption might transiently lower blood pressure due to vessel dilation, there's no consistent evidence of a lasting effect. Overall, the theoretical risk of reduced blood pressure due to beet's nitrate content exists, but studies generally indicate a low and temporary impact rather than a sustained decrease.

Likelihood Possible Evidence A
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, beet might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research suggests that beet induces CYP1A2 enzymes.

Likelihood Possible Evidence D
organic Beet concentrate full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Beta Plus, from the product label.

Biotics Research Corporation

See all Biotics Research Corporation products
Name
BIOTICS RESEARCH CORP.
City
Rosenberg
State
Texas
Phone Number
(281) 344-0909
Pharmacist Counseling Corner

Beta Plus by Biotics Research Corporation: Common Questions

Does Beta Plus by Biotics Research Corporation interact with any medications?
Yes. Based on its ingredients, Beta Plus has a known interaction with 861 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Beta Plus contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will beet concentrate in this product make my blood pressure drop too low?
Beet contains nitrates that can relax blood vessels and lower blood pressure. However, one clinical study using concentrated beetroot juice found no significant impact on blood pressure in different age groups. If you take blood pressure medication, your pharmacist can help you determine whether adding beet is safe for you.
Is it normal if my stools turn red or dark after taking this?
Yes, red stools from beet are harmless—it's just the pigment passing through. Black stools are rarer but have also been reported with beet supplements. Neither means anything is wrong, but if you're on blood thinners and develop black stools with nausea or vomiting, contact your doctor.
Does this product really improve athletic performance?
Organic beet concentrate in this product is rated possibly effective for athletic performance and possibly effective for reducing exercise-induced muscle soreness. The evidence isn't rock-solid, but the research suggests it may help.
What do the other ingredients in Beta Plus do?
This product contains Superoxide Dismutase, Catalase, Ox Bile extract, and Pancrelipase—enzymes and bile compounds traditionally included in digestive support formulas. We hold no effectiveness data for these ingredients in our system.
Is it safe to take this if I'm pregnant or breastfeeding?
We have no pregnancy or breastfeeding safety data on file for the beet or the other ingredients in this product. Talk with your doctor or pharmacist before taking it if you're pregnant or nursing.
Does this product have fillers?
Yes. Besides the five active ingredients, Beta Plus contains cellulose, stearic acid, magnesium stearate, and food glaze as inactive ingredients.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Beta Plus label
Go deeper

The Full Monographs Behind Beta Plus’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Beet

Interacts with 861 drugs

Beet, especially beetroot juice, is a nitrate-rich food that may modestly lower blood pressure and slightly improve exercise performance in some people. It is generally safe as a food, but s...

Read the full Beet monograph →
Sources

Sources & How We Checked

Beta Plus's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Beet 14 references
  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  2. Clifford T, Berntzen B, Davison GW, et al. Effects of beetroot juice on recovery of muscle function and performance between bouts of repeated sprint exercise. Nutrients 2016;8. pii: E506. PubMed
  3. Siervo M, Lara J, Ogbonmwan I, Mathers JC. Inorganic nitrate and beetroot juice supplementation reduces blood pressure in adults: a systematic review and meta-analysis. J Nutr 2013;143:818-26. PubMed
  4. Clifford T, Howatson G, West DJ, Stevenson EJ. Beetroot juice is more beneficial than sodium nitrate for attenuating muscle pain after strenuous eccentric-bias exercise. Appl Physiol Nutr Metab. 2017;42(11):1185-1191. PubMed
  5. Clifford T, Bell O, West DJ, Howatson G, Stevenson EJ. The effects of beetroot juice supplementation on indices of muscle damage following eccentric exercise. Eur J Appl Physiol. 2016;116(2):353-62. PubMed
  6. Wylie LJ, Kelly J, Bailey SJ, et al. Beetroot juice and exercise: pharmacodynamic and dose-response relationships. J Appl Physiol (1985). 2013;115(3):325-36. PubMed
  7. Garnacho-Castaño MV, Palau-Salvà G, Cuenca E, et al. Effects of a single dose of beetroot juice on cycling time trial performance at ventilatory thresholds intensity in male triathletes. J Int Soc Sports Nutr. 2018;15(1):49. PubMed
  8. Rasica L, Porcelli S, Marzorati M, et al. Ergogenic effects of beetroot juice supplementation during severe-intensity exercise in obese adolescents. Am J Physiol Regul Integr Comp Physiol. 2018;315(3):R453-R460. PubMed
  9. Henrohn D, Björkstrand K, Lundberg JO, et al. Effects of oral supplementation with nitrate-rich beetroot juice in patients with pulmonary arterial hypertension-results from BEET-PAH, an exploratory randomized, double-blind, placebo-controlled, crosso
  10. Serra-Payá N, Garnacho-Castaño MV, Sánchez-Nuño S, et al. The relationship between resistance exercise performance and ventilatory efficiency after beetroot juice intake in well-trained athletes. Nutrients 2021;13(4):1094. PubMed
  11. Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
  12. Hemmatinafar M, Zaremoayedi L, Koushkie Jahromi M, et al. Effect of Beetroot Juice Supplementation on Muscle Soreness and Performance Recovery after Exercise-Induced Muscle Damage in Female Volleyball Players. Nutrients 2023;15(17):3763. PubMed
  13. Lim SH, Bae S, Lee HS, Han HK, Choi CI. Effect of Betanin, the Major Pigment of Red Beetroot (Beta vulgaris L.), on the Activity of Recombinant Human Cytochrome P450 Enzymes. Pharmaceuticals (Basel) 2023;16(9):1224. PubMed
  14. Oscherwitz M, Tamayo RM, Heudebert A, Centor R. A Case of Pseudo-Hematochezia from Beet Supplement Ingestion. Am J Med 2023;136(9):e177-e178. PubMed

See these in context on the Beet monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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