Better Stevia Balance Ingredients & Drug Interactions
by NOW
What is this page for?
First and foremost: checking Better Stevia Balance against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Better Stevia Balance is a dietary supplement by NOW with 3 active ingredients. Its ingredients are commonly taken for blood sugar support in type 2 diabetes, weight loss and appetite control, insulin sensitivity.Based on those ingredients, 350 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are certified organic Stevia leaf extract, Chromium, Inulin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Better Stevia Balance by NOW
Ask about any prescription or over-the-counter medication and we check it for interactions with Better Stevia Balance by NOW — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Better Stevia Balance by NOW
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Better Stevia Balance contains three active ingredients in powder form. Chromium helps your body use blood sugar and is rated possibly effective for type 2 diabetes and possibly ineffective for prediabetes and high blood pressure.
Inulin, a prebiotic fiber, is rated possibly effective for constipation and possibly effective for diabetes. Certified organic stevia leaf extract is a natural sweetener with no reliable evidence yet to support its use for diabetes, blood pressure, or weight loss.
The product also contains silica as an inactive ingredient.
Does it work?
Moderate evidence
The evidence for this product's intended uses is mixed. Chromium is rated possibly effective for type 2 diabetes but possibly ineffective for prediabetes and high blood pressure.
Inulin is rated possibly effective for constipation and possibly effective for diabetes. Stevia extract, however, has insufficient reliable evidence to rate for diabetes, high blood pressure, or obesity — meaning the evidence we hold doesn't yet establish whether it works for these purposes.
If you're taking this product for blood sugar control, the chromium and inulin have some research behind them, but stevia's contribution is unproven.
How safe is it?
Well-documented data
Chromium is generally well tolerated at typical supplement doses, though high or long-term doses may carry risks. The most common side effects are gastrointestinal irritation, headaches, insomnia, irritability, and mood changes.
Rare cases of kidney or liver damage, muscle breakdown, and low platelets have been reported. Inulin is well tolerated but often causes gas, bloating, diarrhea, and cramping, especially at higher doses — so start low if you're sensitive to fiber.
Stevia and its active compounds are generally well tolerated, with minor side effects like bloating, dizziness, headache, and muscle pain that usually resolve within a week; allergic reactions are rare. For pregnancy and lactation: chromium small amounts from diet or prenatal vitamins are considered acceptable, but extra supplement doses should be avoided unless your doctor recommends them.
Inulin is rated likely safe in pregnancy and lactation. Stevia's pregnancy and lactation safety rating is not on file.
Meds to double-check
Moderate interaction found
Check with your pharmacist if you take antidiabetes drugs or insulin (risk of low blood sugar), levothyroxine or other thyroid medication (chromium may reduce absorption), lithium (stevia may raise lithium levels), blood pressure medications (stevia may lower pressure further), NSAIDs or aspirin (may increase chromium levels), or any blood thinners. No interactions are documented for the ingredients we could check beyond those listed.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product may help with blood sugar control or constipation, but it requires careful checking if you take thyroid medication, diabetes drugs, insulin, blood pressure medications, or lithium. Start with your pharmacist or doctor to make sure none of your medications are affected.
If you tolerate the ingredients well and have clearance from your healthcare provider, it's generally well tolerated, though expect some bloating or digestive changes from the inulin.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 23, 2017.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Better Stevia Balance, straight from the product label.
| Brand | NOW |
|---|---|
| Barcode (UPC) | 733739069689 |
| Net contents | 100 Packet(s); 3.9 oz.; 110 Gram(s) |
| Market status | On market |
| Date entered into DSLD | Jun 23, 2017 |
| DSLD ID | 74051 |
| Product type | Botanical With Nutrients |
| Supplement form | Powder |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Better Stevia Balance by NOW, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 0 Calorie(s) | -- |
| Total Carbohydrates | 1 Gram(s) | 1% |
| Added Sugars | 0 Gram(s) | -- |
| Total Sugars | 0 Gram(s) | -- |
| Chromium | 50 mcg | 143% |
| Inulin | 900 mg | -- |
| certified organic Stevia leaf extract | 130 mg | -- |
Other ingredients: Silica
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
BetterStevia Balance is a unique natural product that combines stevia, chromium and inulin in one convenient packet that is ideally suited to support healthy glucose metabolism.* The “balance” in BetterStevia Balance comes from inulin and chromium.
BetterStevia utilizes a whole leaf extract that retains the natural properties of real stevia, as opposed to other products that have only isolated fractions, such as Rebaudiana A (Reb A). Our stevia is produced using a special enzymatic treatment that results in a clean, pure, well-rounded, less bitter stevia extract.
With Chromium & Inulin
Triangle K
General Statements
Inulin is a non-digestible carbohydrate from the chicory plant’s roots that’s utilized as food by the healthy probiotic bacteria in the gut.* Chromium is an essential dietary mineral that is necessary for the body’s normal metabolism of glucose.*
Try our other BetterStevia products Packets ~ Liquids ~ Powders Natural ~ Low glycemic ~ Sugar free
New look! Same great taste
Packaged in the USA Please recycle. This carton is made from 100% recyclable material.
CRTN6968B
FDA Disclaimer Statement
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Brand IP Statement(s)
Why BetterStevia is imply better.
Chromium Chelavite is a registered trademark of Albion Laboratories.
Formulation
Our focus on quality, purity and freshness gives our stevia its well-rounded, natural, zero-calorie profile and puts the better into BetterStevia!
Zero calories Gluten-free Nothing artificial
Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients.
Vegetarian/Vegan product.
General
CODE B6968 V8
Seals/Symbols
Triangle K
FDA Statement of Identity
A Dietary Supplement
Precautions
Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.
Caution: Due to micronutrient content, do not use more than 8 packets per day.
Consult physician if pregnant/nursing, taking medication, or have a medical condition (especially diabetes or blood sugar irregularities).
Keep out of reach of children.
Suggested/Recommended/Usage/Directions
Suggested Use: Take one packet as desired.
Storage
Store in a cool, dry place after opening.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Better Stevia Balance by NOW label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Better Stevia Balance by NOW
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size1.1 Gram(s) Dosage formPowder Servings per container100 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Chromium
Interacts with178 drugs
Chromium is an essential trace mineral involved in how the body handles sugar and fat. Some studies suggest it may modestly help blood sugar control i...
Chromium monograph & interactionsInulin
Interacts with86 drugs
Inulin is a type of plant fiber (a prebiotic) found naturally in foods like chicory root, onions, and garlic, and it is widely added to supplements an...
Inulin monograph & interactionsCertified organic Stevia leaf extract
Interacts with259 drugs
Stevia is a plant-based, calorie-free sweetener that is widely used as a sugar alternative and is considered safe in normal food amounts by major regu...
Certified organic Stevia leaf extract monograph & interactionsOther (inactive) ingredients: Silica. These complete the product’s ingredient list but are not active constituents.
Better Stevia Balance by NOW Drug Interactions
HelloPharmacist Interaction Report
Better Stevia Balance by NOW contains three active ingredients, and together they interact with a significant number of medications.
Chromium is the primary concern: it has Moderate interactions with antidiabetes drugs and insulin — both can increase your risk of low blood sugar (hypoglycemia) — and a Moderate interaction with levothyroxine (thyroid medication), where chromium may reduce how much of the drug your body absorbs. Clinical research shows chromium can lower levothyroxine levels by about 17%.
Read the full breakdown — every affected drug type, severity by severity
Stevia extract carries a Moderate interaction with lithium, a psychiatric medication, potentially raising lithium levels in your blood to unsafe ranges. Stevia also has Minor interactions with blood pressure medications and antidiabetes drugs, where it might lower your blood pressure or blood sugar more than intended.
Inulin, the third ingredient, has a Minor interaction with antidiabetes drugs and theoretically could add to their blood-sugar-lowering effect.
Chromium also interacts with NSAIDs (like ibuprofen) and aspirin at Minor severity, where these pain relievers may increase chromium absorption and raise its levels. Altogether, these interactions span 347 individual medications.
If you take any of these drug types — especially blood thinners, thyroid medication, diabetes drugs, insulin, or lithium — check your exact medications with the tool on this page before starting this supplement.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Better Stevia Balance?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Better Stevia Balance interact with 350 drugs. Click any drug to see the details.
3 of the 3 ingredients in Better Stevia Balance interact with drugs. Each result below shows which ingredient is responsible. certified organic Stevia leaf extract Chromium Inulin
AcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Better Stevia Balance — through 3 ingredients. Tap an ingredient for the detail:
ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Chromium + Acarbose interactionInulinAntidiabetes Drugs Minor
Interaction Summary
Theoretically, inulin might increase the risk of hypoglycemia with antidiabetes drugs.
Read the full Inulin + Acarbose interactionCertified Organic Stevia Leaf ExtractAntidiabetes Drugs Minor
Interaction Summary
Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Read the full Certified Organic Stevia Leaf Extract + Acarbose interactionAcetohexamideDymelor
How Acetohexamide interacts with Better Stevia Balance — through 3 ingredients. Tap an ingredient for the detail:
ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Chromium + Acetohexamide interactionCertified Organic Stevia Leaf ExtractAntidiabetes Drugs Minor
Interaction Summary
Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Read the full Certified Organic Stevia Leaf Extract + Acetohexamide interactionInulinAntidiabetes Drugs Minor
Interaction Summary
Theoretically, inulin might increase the risk of hypoglycemia with antidiabetes drugs.
Read the full Inulin + Acetohexamide interactionAlbiglutideTanzeum
How Albiglutide interacts with Better Stevia Balance — through 3 ingredients. Tap an ingredient for the detail:
ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Chromium + Albiglutide interactionCertified Organic Stevia Leaf ExtractAntidiabetes Drugs Minor
Interaction Summary
Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Read the full Certified Organic Stevia Leaf Extract + Albiglutide interactionInulinAntidiabetes Drugs Minor
Interaction Summary
Theoretically, inulin might increase the risk of hypoglycemia with antidiabetes drugs.
Read the full Inulin + Albiglutide interactionAlogliptinNesina
How Alogliptin interacts with Better Stevia Balance — through 3 ingredients. Tap an ingredient for the detail:
ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Chromium + Alogliptin interactionCertified Organic Stevia Leaf ExtractAntidiabetes Drugs Minor
Interaction Summary
Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Read the full Certified Organic Stevia Leaf Extract + Alogliptin interactionInulinAntidiabetes Drugs Minor
Interaction Summary
Theoretically, inulin might increase the risk of hypoglycemia with antidiabetes drugs.
Read the full Inulin + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Better Stevia Balance — through 3 ingredients. Tap an ingredient for the detail:
ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Chromium + Alogliptin, Metformin interactionInulinAntidiabetes Drugs Minor
Interaction Summary
Theoretically, inulin might increase the risk of hypoglycemia with antidiabetes drugs.
Read the full Inulin + Alogliptin, Metformin interactionCertified Organic Stevia Leaf ExtractAntidiabetes Drugs Minor
Interaction Summary
Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Read the full Certified Organic Stevia Leaf Extract + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Better Stevia Balance — through 3 ingredients. Tap an ingredient for the detail:
ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Chromium + Alogliptin, Pioglitazone interactionInulinAntidiabetes Drugs Minor
Interaction Summary
Theoretically, inulin might increase the risk of hypoglycemia with antidiabetes drugs.
Read the full Inulin + Alogliptin, Pioglitazone interactionCertified Organic Stevia Leaf ExtractAntidiabetes Drugs Minor
Interaction Summary
Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Read the full Certified Organic Stevia Leaf Extract + Alogliptin, Pioglitazone interactionAntidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) InhibitorGlyxambi
How Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interacts with Better Stevia Balance — through 3 ingredients. Tap an ingredient for the detail:
ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Chromium + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interactionCertified Organic Stevia Leaf ExtractAntidiabetes Drugs Minor
Interaction Summary
Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Read the full Certified Organic Stevia Leaf Extract + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interactionInulinAntidiabetes Drugs Minor
Interaction Summary
Theoretically, inulin might increase the risk of hypoglycemia with antidiabetes drugs.
Read the full Inulin + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interactionCanagliflozinInvokana
How Canagliflozin interacts with Better Stevia Balance — through 3 ingredients. Tap an ingredient for the detail:
ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Chromium + Canagliflozin interactionCertified Organic Stevia Leaf ExtractAntidiabetes Drugs Minor
Interaction Summary
Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Read the full Certified Organic Stevia Leaf Extract + Canagliflozin interactionInulinAntidiabetes Drugs Minor
Interaction Summary
Theoretically, inulin might increase the risk of hypoglycemia with antidiabetes drugs.
Read the full Inulin + Canagliflozin interactionCanagliflozin, MetforminInvokamet
How Canagliflozin, Metformin interacts with Better Stevia Balance — through 3 ingredients. Tap an ingredient for the detail:
ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Chromium + Canagliflozin, Metformin interactionInulinAntidiabetes Drugs Minor
Interaction Summary
Theoretically, inulin might increase the risk of hypoglycemia with antidiabetes drugs.
Read the full Inulin + Canagliflozin, Metformin interactionCertified Organic Stevia Leaf ExtractAntidiabetes Drugs Minor
Interaction Summary
Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Read the full Certified Organic Stevia Leaf Extract + Canagliflozin, Metformin interactionCanagliflozin, Metformin HydrochlorideInvokamet XR
How Canagliflozin, Metformin Hydrochloride interacts with Better Stevia Balance — through 3 ingredients. Tap an ingredient for the detail:
ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Chromium + Canagliflozin, Metformin Hydrochloride interactionInulinAntidiabetes Drugs Minor
Interaction Summary
Theoretically, inulin might increase the risk of hypoglycemia with antidiabetes drugs.
Read the full Inulin + Canagliflozin, Metformin Hydrochloride interactionCertified Organic Stevia Leaf ExtractAntidiabetes Drugs Minor
Interaction Summary
Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Read the full Certified Organic Stevia Leaf Extract + Canagliflozin, Metformin Hydrochloride interactionChlorpropamideChlorpropam, Diabinese
How Chlorpropamide interacts with Better Stevia Balance — through 3 ingredients. Tap an ingredient for the detail:
ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Chromium + Chlorpropamide interactionCertified Organic Stevia Leaf ExtractAntidiabetes Drugs Minor
Interaction Summary
Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Read the full Certified Organic Stevia Leaf Extract + Chlorpropamide interactionInulinAntidiabetes Drugs Minor
Interaction Summary
Theoretically, inulin might increase the risk of hypoglycemia with antidiabetes drugs.
Read the full Inulin + Chlorpropamide interactionDapagliflozinFarxiga
How Dapagliflozin interacts with Better Stevia Balance — through 3 ingredients. Tap an ingredient for the detail:
ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Chromium + Dapagliflozin interactionCertified Organic Stevia Leaf ExtractAntidiabetes Drugs Minor
Interaction Summary
Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Read the full Certified Organic Stevia Leaf Extract + Dapagliflozin interactionInulinAntidiabetes Drugs Minor
Interaction Summary
Theoretically, inulin might increase the risk of hypoglycemia with antidiabetes drugs.
Read the full Inulin + Dapagliflozin interactionDapagliflozin Propanediol, MetforminXigduo XR
How Dapagliflozin Propanediol, Metformin interacts with Better Stevia Balance — through 3 ingredients. Tap an ingredient for the detail:
ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Chromium + Dapagliflozin Propanediol, Metformin interactionCertified Organic Stevia Leaf ExtractAntidiabetes Drugs Minor
Interaction Summary
Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Read the full Certified Organic Stevia Leaf Extract + Dapagliflozin Propanediol, Metformin interactionInulinAntidiabetes Drugs Minor
Interaction Summary
Theoretically, inulin might increase the risk of hypoglycemia with antidiabetes drugs.
Read the full Inulin + Dapagliflozin Propanediol, Metformin interactionDapagliflozin Propanediol, Saxagliptin HydrochlorideQtern
How Dapagliflozin Propanediol, Saxagliptin Hydrochloride interacts with Better Stevia Balance — through 3 ingredients. Tap an ingredient for the detail:
ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Chromium + Dapagliflozin Propanediol, Saxagliptin Hydrochloride interactionInulinAntidiabetes Drugs Minor
Interaction Summary
Theoretically, inulin might increase the risk of hypoglycemia with antidiabetes drugs.
Read the full Inulin + Dapagliflozin Propanediol, Saxagliptin Hydrochloride interactionCertified Organic Stevia Leaf ExtractAntidiabetes Drugs Minor
Interaction Summary
Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Read the full Certified Organic Stevia Leaf Extract + Dapagliflozin Propanediol, Saxagliptin Hydrochloride interactionDapagliflozin, Metformin Hydrochloride, Saxagliptin HydrochlorideQternmet XR
How Dapagliflozin, Metformin Hydrochloride, Saxagliptin Hydrochloride interacts with Better Stevia Balance — through 3 ingredients. Tap an ingredient for the detail:
ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Chromium + Dapagliflozin, Metformin Hydrochloride, Saxagliptin Hydrochloride interactionCertified Organic Stevia Leaf ExtractAntidiabetes Drugs Minor
Interaction Summary
Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Read the full Certified Organic Stevia Leaf Extract + Dapagliflozin, Metformin Hydrochloride, Saxagliptin Hydrochloride interactionInulinAntidiabetes Drugs Minor
Interaction Summary
Theoretically, inulin might increase the risk of hypoglycemia with antidiabetes drugs.
Read the full Inulin + Dapagliflozin, Metformin Hydrochloride, Saxagliptin Hydrochloride interactionDasiglucagon HydrochlorideZegalogue
How Dasiglucagon Hydrochloride interacts with Better Stevia Balance — through 3 ingredients. Tap an ingredient for the detail:
ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Chromium + Dasiglucagon Hydrochloride interactionInulinAntidiabetes Drugs Minor
Interaction Summary
Theoretically, inulin might increase the risk of hypoglycemia with antidiabetes drugs.
Read the full Inulin + Dasiglucagon Hydrochloride interactionCertified Organic Stevia Leaf ExtractAntidiabetes Drugs Minor
Interaction Summary
Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Read the full Certified Organic Stevia Leaf Extract + Dasiglucagon Hydrochloride interactionDulaglutideTrulicity
How Dulaglutide interacts with Better Stevia Balance — through 3 ingredients. Tap an ingredient for the detail:
ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Chromium + Dulaglutide interactionCertified Organic Stevia Leaf ExtractAntidiabetes Drugs Minor
Interaction Summary
Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Read the full Certified Organic Stevia Leaf Extract + Dulaglutide interactionInulinAntidiabetes Drugs Minor
Interaction Summary
Theoretically, inulin might increase the risk of hypoglycemia with antidiabetes drugs.
Read the full Inulin + Dulaglutide interactionEmpagliflozinJardiance
How Empagliflozin interacts with Better Stevia Balance — through 3 ingredients. Tap an ingredient for the detail:
ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Chromium + Empagliflozin interactionCertified Organic Stevia Leaf ExtractAntidiabetes Drugs Minor
Interaction Summary
Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Read the full Certified Organic Stevia Leaf Extract + Empagliflozin interactionInulinAntidiabetes Drugs Minor
Interaction Summary
Theoretically, inulin might increase the risk of hypoglycemia with antidiabetes drugs.
Read the full Inulin + Empagliflozin interactionEmpagliflozin, Linagliptin, Metformin HydrochlorideTrijardy XR
How Empagliflozin, Linagliptin, Metformin Hydrochloride interacts with Better Stevia Balance — through 3 ingredients. Tap an ingredient for the detail:
ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Chromium + Empagliflozin, Linagliptin, Metformin Hydrochloride interactionInulinAntidiabetes Drugs Minor
Interaction Summary
Theoretically, inulin might increase the risk of hypoglycemia with antidiabetes drugs.
Read the full Inulin + Empagliflozin, Linagliptin, Metformin Hydrochloride interactionCertified Organic Stevia Leaf ExtractAntidiabetes Drugs Minor
Interaction Summary
Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Read the full Certified Organic Stevia Leaf Extract + Empagliflozin, Linagliptin, Metformin Hydrochloride interactionEmpagliflozin, MetforminSynjardy
How Empagliflozin, Metformin interacts with Better Stevia Balance — through 3 ingredients. Tap an ingredient for the detail:
ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Chromium + Empagliflozin, Metformin interactionCertified Organic Stevia Leaf ExtractAntidiabetes Drugs Minor
Interaction Summary
Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Read the full Certified Organic Stevia Leaf Extract + Empagliflozin, Metformin interactionInulinAntidiabetes Drugs Minor
Interaction Summary
Theoretically, inulin might increase the risk of hypoglycemia with antidiabetes drugs.
Read the full Inulin + Empagliflozin, Metformin interactionEmpagliflozin, Metformin HydrochlorideSynjardy XR
How Empagliflozin, Metformin Hydrochloride interacts with Better Stevia Balance — through 3 ingredients. Tap an ingredient for the detail:
ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Chromium + Empagliflozin, Metformin Hydrochloride interactionInulinAntidiabetes Drugs Minor
Interaction Summary
Theoretically, inulin might increase the risk of hypoglycemia with antidiabetes drugs.
Read the full Inulin + Empagliflozin, Metformin Hydrochloride interactionCertified Organic Stevia Leaf ExtractAntidiabetes Drugs Minor
Interaction Summary
Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Read the full Certified Organic Stevia Leaf Extract + Empagliflozin, Metformin Hydrochloride interactionErtugliflozinSteglatro
How Ertugliflozin interacts with Better Stevia Balance — through 3 ingredients. Tap an ingredient for the detail:
ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Chromium + Ertugliflozin interactionInulinAntidiabetes Drugs Minor
Interaction Summary
Theoretically, inulin might increase the risk of hypoglycemia with antidiabetes drugs.
Read the full Inulin + Ertugliflozin interactionCertified Organic Stevia Leaf ExtractAntidiabetes Drugs Minor
Interaction Summary
Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Read the full Certified Organic Stevia Leaf Extract + Ertugliflozin interactionErtugliflozin, Metformin HydrochlorideSegluromet
How Ertugliflozin, Metformin Hydrochloride interacts with Better Stevia Balance — through 3 ingredients. Tap an ingredient for the detail:
ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Chromium + Ertugliflozin, Metformin Hydrochloride interactionCertified Organic Stevia Leaf ExtractAntidiabetes Drugs Minor
Interaction Summary
Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Read the full Certified Organic Stevia Leaf Extract + Ertugliflozin, Metformin Hydrochloride interactionInulinAntidiabetes Drugs Minor
Interaction Summary
Theoretically, inulin might increase the risk of hypoglycemia with antidiabetes drugs.
Read the full Inulin + Ertugliflozin, Metformin Hydrochloride interactionExenatideBydureon, Byetta
How Exenatide interacts with Better Stevia Balance — through 3 ingredients. Tap an ingredient for the detail:
ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Chromium + Exenatide interactionInulinAntidiabetes Drugs Minor
Interaction Summary
Theoretically, inulin might increase the risk of hypoglycemia with antidiabetes drugs.
Read the full Inulin + Exenatide interactionCertified Organic Stevia Leaf ExtractAntidiabetes Drugs Minor
Interaction Summary
Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Read the full Certified Organic Stevia Leaf Extract + Exenatide interactionExenatide SyntheticBydureon BCISE
How Exenatide Synthetic interacts with Better Stevia Balance — through 3 ingredients. Tap an ingredient for the detail:
ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Chromium + Exenatide Synthetic interactionCertified Organic Stevia Leaf ExtractAntidiabetes Drugs Minor
Interaction Summary
Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Read the full Certified Organic Stevia Leaf Extract + Exenatide Synthetic interactionInulinAntidiabetes Drugs Minor
Interaction Summary
Theoretically, inulin might increase the risk of hypoglycemia with antidiabetes drugs.
Read the full Inulin + Exenatide Synthetic interactionGliclazideDiamicron
How Gliclazide interacts with Better Stevia Balance — through 3 ingredients. Tap an ingredient for the detail:
ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Chromium + Gliclazide interactionCertified Organic Stevia Leaf ExtractAntidiabetes Drugs Minor
Interaction Summary
Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Read the full Certified Organic Stevia Leaf Extract + Gliclazide interactionInulinAntidiabetes Drugs Minor
Interaction Summary
Theoretically, inulin might increase the risk of hypoglycemia with antidiabetes drugs.
Read the full Inulin + Gliclazide interactionGlimepirideAmaryl
How Glimepiride interacts with Better Stevia Balance — through 3 ingredients. Tap an ingredient for the detail:
ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Chromium + Glimepiride interactionInulinAntidiabetes Drugs Minor
Interaction Summary
Theoretically, inulin might increase the risk of hypoglycemia with antidiabetes drugs.
Read the full Inulin + Glimepiride interactionCertified Organic Stevia Leaf ExtractAntidiabetes Drugs Minor
Interaction Summary
Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Read the full Certified Organic Stevia Leaf Extract + Glimepiride interactionGlipizideGlucotrol, Glucotrol XL
How Glipizide interacts with Better Stevia Balance — through 3 ingredients. Tap an ingredient for the detail:
ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Chromium + Glipizide interactionInulinAntidiabetes Drugs Minor
Interaction Summary
Theoretically, inulin might increase the risk of hypoglycemia with antidiabetes drugs.
Read the full Inulin + Glipizide interactionCertified Organic Stevia Leaf ExtractAntidiabetes Drugs Minor
Interaction Summary
Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Read the full Certified Organic Stevia Leaf Extract + Glipizide interactionGlipizide, MetforminMetaglip
How Glipizide, Metformin interacts with Better Stevia Balance — through 3 ingredients. Tap an ingredient for the detail:
ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Chromium + Glipizide, Metformin interactionCertified Organic Stevia Leaf ExtractAntidiabetes Drugs Minor
Interaction Summary
Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Read the full Certified Organic Stevia Leaf Extract + Glipizide, Metformin interactionInulinAntidiabetes Drugs Minor
Interaction Summary
Theoretically, inulin might increase the risk of hypoglycemia with antidiabetes drugs.
Read the full Inulin + Glipizide, Metformin interactionGlucagonBaqsimi, Glucagon
How Glucagon interacts with Better Stevia Balance — through 3 ingredients. Tap an ingredient for the detail:
ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Chromium + Glucagon interactionInulinAntidiabetes Drugs Minor
Interaction Summary
Theoretically, inulin might increase the risk of hypoglycemia with antidiabetes drugs.
Read the full Inulin + Glucagon interactionCertified Organic Stevia Leaf ExtractAntidiabetes Drugs Minor
Interaction Summary
Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Read the full Certified Organic Stevia Leaf Extract + Glucagon interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Better Stevia Balance with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
certified organic Stevia leaf extract
Lithium
Theoretically, stevia might decrease clearance and increase levels of lithium.
Animal research suggests that stevia extracts might have diuretic activity. Theoretically, increased reabsorption of lithium along with sodium might reduce excretion and increase levels of lithium.
Antidiabetes Drugs
Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Preliminary clinical research in patients with type 2 diabetes suggests that taking a single dose of stevia extract 1000 mg reduces postprandial blood glucose levels when taken with a meal. However, other clinical research in patients with type 1 or type 2 diabetes suggests that taking stevioside 250 mg three times daily does not significantly affect blood glucose levels or glycated hemoglobin (HbA1C) after three months of treatment.
Antihypertensive Drugs
Theoretically, combining stevia or stevia constituents with antihypertensive agents might increase the risk of hypotension.
Stevia extract and stevioside might lower blood pressure in patients with hypertension. However, other clinical research suggests that stevioside does not significantly lower blood pressure in patients with hypertension.
Chromium
Antidiabetes Drugs
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Some research shows that taking chromium might lower blood glucose levels, especially in patients with poorly controlled type 2 diabetes.
Insulin
Theoretically, concomitant use of chromium and insulin might increase the risk of hypoglycemia.
In clinical research, chromium has been shown to increase insulin sensitivity,
Levothyroxine (Synthroid, Others)
Chromium might bind levothyroxine in the intestinal tract and decrease levothyroxine absorption.
Clinical research in healthy volunteers shows that taking chromium picolinate 1000 mcg with levothyroxine 1 mg decreases serum levels of levothyroxine by 17% when compared to taking levothyroxine alone. Advise patients to take levothyroxine at least 30 minutes before or 3-4 hours after taking chromium.
Aspirin
Theoretically, aspirin might increase chromium absorption.
Animal research suggests that aspirin may increase chromium absorption and chromium levels in the blood.
Nonsteroidal Anti-Inflammatory Drugs (Nsaids)
NSAIDs might increase chromium levels in the body.
Drugs that are prostaglandin inhibitors, such as NSAIDs, seem to increase chromium absorption and retention.
Inulin
Antidiabetes Drugs
Theoretically, inulin might increase the risk of hypoglycemia with antidiabetes drugs.
Some clinical research shows that inulin improves glycemic control in patients with diabetes; however, it is unclear if it has hypoglycemic effects.
Brand information
Manufacturer and brand details for Better Stevia Balance, from the product label.
NOW
See all NOW products- Name
- NOW Foods
- Street Address
- 395 S. Glen Ellyn Rd.
- City
- Bloomingdale
- State
- IL
- ZipCode
- 60108
- Web Address
- BetterStevia.com
Better Stevia Balance by NOW: Common Questions
Does Better Stevia Balance by NOW interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will this help my blood sugar?
What are the most common side effects?
Is this safe during pregnancy?
Why can't I just take this with my levothyroxine?
I take ibuprofen regularly. Is that a problem?
What's inulin doing in a stevia product?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Better Stevia Balance is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Better Stevia Balance’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Chromium
Interacts with 178 drugsChromium is an essential trace mineral involved in how the body handles sugar and fat. Some studies suggest it may modestly help blood sugar control in certain people with type 2 diabetes, b...
Read the full Chromium monograph → Herb & supplement monographInulin
Interacts with 86 drugsInulin is a type of plant fiber (a prebiotic) found naturally in foods like chicory root, onions, and garlic, and it is widely added to supplements and processed foods. It may help with regu...
Read the full Inulin monograph → Herb & supplement monographStevia
Interacts with 259 drugsStevia is a plant-based, calorie-free sweetener that is widely used as a sugar alternative and is considered safe in normal food amounts by major regulators. Purified stevia extracts have a...
Read the full Stevia monograph →Sources & How We Checked
Better Stevia Balance's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 80 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Chromium 53 references
- Cerulli J, Grabe DW, Gauthier I, et al. Chromium picolinate toxicity. Ann Pharmacother 1998;32:428-31. PubMed
- Urberg M, Zemel MB. Evidence for synergism between chromium and nicotinic acid in the control of glucose tolerance in elderly humans. Metabolism 1987;36:896-9. PubMed
- Mohamedshah FY, Moser-Veillon PB, Yamini S, et al. Distribution of a stable isotope of chromium (53Cr) in serum, urine, and breast milk in lactating women. Am J Clin Nutr 1998;67:1250-5. PubMed
- Wasser WG, Feldman NS, D'Agati VD. Chronic renal failure after ingestion of over-the-counter chromium picolinate. [letter]. Ann Intern Med 1997;126:410. PubMed
- Mertz W. Interaction of chromium with insulin: a progress report. Nutr Rev 1998;56:174-7. PubMed
- Anderson RA. Chromium, glucose intolerance and diabetes. J Am Coll Nutr 1998;17:548-55. PubMed
- McLeod MN, Gaynes BN, Golden RN. Chromium potentiation of antidepressant pharmacotherapy for dysthymic disorder in 5 patients. J Clin Psych 1999;60:237-40. PubMed
- Fowler JF Jr. Systemic contact dermatitis caused by oral chromium picolinate. Cutis 2000;65:116. DOI
- Trent LK, Thieding-Cancel D. Effects of chromium picolinate on body composition. J Sports Med Phys Fitness 1995;35:273-80.
- Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
- Rabinovitz H, Friedensohn A, Leibovitz A, et al. Effect of chromium supplementation on blood glucose and lipid levels in type 2 diabetes mellitus elderly patients. Int J Vitam Nutr Res 2004;74:178-82. PubMed
- Lanca S, Alves A, Vieira AI, et al. Chromium-induced toxic hepatitis. Eur J Intern Med 2002;13:518-20. PubMed
- Kockler DR, McCarthy MW, Lawson CL. Seizure activity and unresponsiveness after hydroxycut ingestion. Pharmacotherapy 2001;21:647-51.. PubMed
- Davidson JR, Abraham K, Connor KM, McLeod MN. Effectiveness of chromium in atypical depression: a placebo-controlled trial. Biol Psychiatry 2003;53:261-4.. PubMed
- Food Standards Agency. Medicines and Healthcare products Regulatory Agency (MHRA). Expert Group on Vitamins and Minerals. Available at: http://cot.food.gov.uk/sites/default/files/vitmin2003.pdf.
- Mouser JF, Hak EB, Helms RA, et al. Chromium and zinc concentrations in pediatric patients receiving long-term parenteral nutrition. Am J Health Syst Pharm 1999;56:1950-6. PubMed
- Stevens T, Qadri A, Zein NN. Two patients with acute liver injury associated with use of the herbal weight-loss supplement hydroxycut. Ann Intern Med 2005;142:477-8. PubMed
- Wani S, Weskamp C, Marple J, Spry L. Acute tubular necrosis associated with chromium picolinate-containing dietary supplement. Ann Pharmacother 2006;40:563-6. PubMed
- Kleefstra N, Houweling ST, Jansman FG, et al. Chromium treatment has no effect in patients with poorly controlled, insulin-treated type 2 diabetes in an obese Western population: a randomized, double-blind, placebo-controlled trial. Diabetes Care 2006;29: PubMed
- Martin J, Wang ZQ, Zhang XH, et al. Chromium picolinate supplementation attenuates body weight gain and increases insulin sensitivity in subjects with type 2 diabetes. Diabetes Care 2006;29:1826-32. PubMed
- Singer GM, Geohas J. The effect of chromium picolinate and biotin supplementation on glycemic control in poorly controlled patients with type 2 diabetes mellitus: a placebo-controlled, double-blinded, randomized trial. Diabetes Technol Ther 2006;8:636-43. PubMed
- John-Kalarickal J, Pearlman G, Carlson HE. New medications which decrease levothyroxine absorption. Thyroid 2007;17:763-5. PubMed
- Yazaki Y, Faridi Z, Ma Y, et al. A pilot study of chromium picolinate for weight loss. J Altern Complement Med 2010;16:291-9. PubMed
- Davis ML, Seaborn CD, and Stoecker BJ. Effects of over-the-counter drugs on chromium retention and urinary excretion in rats. Nutrition Research 1995;15(2):201-210.
- Young P, Turiansky G, Bonner M, and et al. Acute generalized exanthematous pustulosis induced by chromium picolinate. J.Am Acad.Dermatol. 1999;41(5 Pt 2):820-823. PubMed
- Gibb, H. J., Lees, P. S., Pinsky, P. F., and Rooney, B. C. Lung cancer among workers in chromium chemical production. Am J Ind.Med 2000;38(2):115-126. DOI
- Gibb, H. J., Lees, P. S., Pinsky, P. F., and Rooney, B. C. Clinical findings of irritation among chromium chemical production workers. Am J Ind.Med 2000;38(2):127-131. PubMed
- Pittler, M. H. and Ernst, E. Dietary supplements for body-weight reduction: a systematic review. Am.J.Clin Nutr. 2004;79(4):529-536. PubMed
- Pei, D., Hsieh, C. H., Hung, Y. J., Li, J. C., Lee, C. H., and Kuo, S. W. The influence of chromium chloride-containing milk to glycemic control of patients with type 2 diabetes mellitus: a randomized, double-blind, placebo-controlled trial. Metabolism 2 PubMed
- Hisatomi, K., Ishii, H., Hashiguchi, K., Seki, M., Ide, M., Sugiyama, K., Ishimoto, H., Nakayama, S., Mukae, H., and Kohno, S. Interstitial pneumonia caused by inhalation of fumes of nickel and chrome. Respirology. 2006;11(6):814-817. PubMed
- Kleefstra, N., Houweling, S. T., Bakker, S. J., Verhoeven, S., Gans, R. O., Meyboom-de Jong, B., and Bilo, H. J. Chromium treatment has no effect in patients with type 2 diabetes in a Western population: a randomized, double-blind, placebo-controlled tri DOI
- Parsons, A., Ingram, J., Inglis, J., Aveyard, P., Johnstone, E., Brown, K., Franklin, M., and Bermudez, I. A proof of concept randomised placebo controlled factorial trial to examine the efficacy of St John's wort for smoking cessation and chromium to pr
- Bagdon RE and Hazen RE. Skin permeation and cutaneous hypersensitivity as a basis for making risk assessments of chromium as a soil contaminant. Environ.Health Perspect. 1991;92:111-119. PubMed
- Bharmal, S. V., Moyes, V., Ahmed, S., and Grossman, A. Hypoglycaemia: possible mediation by chromium salt medication. Hormones.(Athens.) 2010;9(2):181-183. PubMed
- Krol, E., Krejpcio, Z., Byks, H., Bogdanski, P., and Pupek-Musialik, D. Effects of chromium brewer's yeast supplementation on body mass, blood carbohydrates, and lipids and minerals in type 2 diabetic patients. Biol.Trace Elem.Res. 2011;143(2):726-737.
- Unisa, S., Jagannath, P., Dhir, V., Khandelwal, C., Sarangi, L., and Roy, T. K. Population-based study to estimate prevalence and determine risk factors of gallbladder diseases in the rural Gangetic basin of North India. HPB (Oxford) 2011;13(2):117-125. PubMed
- Noda, S., Asano, Y., and Sato, S. Lichen planus in a patient with long-term exposure to chrome. Eur.J.Dermatol. 2011;21(3):417-418. PubMed
- Xiang, J., Sun, Z., and Huan, J. N. Intensive chromic acid burns and acute chromium poisoning with acute renal failure. Chin Med.J.(Engl.) 7-5-2011;124(13):2071-2073.
- Chhabra, D., Oda, K., Jagannath, P., Utsunomiya, H., Takekoshi, S., and Nimura, Y. Chronic heavy metal exposure and gallbladder cancer risk in India, a comparative study with Japan. Asian Pac.J.Cancer Prev. 2012;13(1):187-190. PubMed
- Huszonek, J. Over-the-counter chromium picolinate. Am J Psychiatry 1993;150(10):1560-1561. PubMed
- Bunner S and McGinnis R. Chromium-induced hypoglycemia. Psychosomatics 1998;39(3):298-299. PubMed
- Martin, W. R. and Fuller, R. E. Suspected chromium picolinate-induced rhabdomyolysis. Pharmacotherapy 1998;18(4):860-862. DOI
- Proctor, D. M., Fredrick, M. M., Scott, P. K., Paustenbach, D. J., and Finley, B. L. The prevalence of chromium allergy in the United States and its implications for setting soil cleanup: a cost-effectiveness case study. Regul.Toxicol Pharmacol 1998;28(1 PubMed
- De Marchi S, Cecchin E, De Marchi SU. Systemic allergic dermatitis resulting from oral administration of chromium with a food supplement. Contact Dermatitis 2014;70(2):123-5. PubMed
- Hedberg YS, Gumulka M, Lind ML, Matura M, Lidén C. Severe occupational chromium allergy despite cement legislation. Contact Dermatitis. 2014;70(5):321-3. PubMed
- Thyssen JP, Jellesen MS, Møller P, Menné T, Johansen JD. Allergic chromium dermatitis from wearing 'chromium-free' footwear. Contact Dermatitis 2014;70(3):185-7. PubMed
- Liu Y, Cotillard A, Vatier C, et al. A Dietary Supplement Containing Cinnamon, Chromium and Carnosine Decreases Fasting Plasma Glucose and Increases Lean Mass in Overweight or Obese Pre-Diabetic Subjects: A Randomized, Placebo-Controlled Trial. PLoS One.
- Jamilian M, Asemi Z. Chromium Supplementation and the Effects on Metabolic Status in Women with Polycystic Ovary Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial. Ann Nutr Metab. 2015;67(1):42-8. PubMed
- Guimarães MM, Carvalho AC, Silva MS. Effect of chromium supplementation on the glucose homeostasis and anthropometry of type 2 diabetic patients: Double blind, randomized clinical trial: Chromium, glucose homeostasis and anthropometry. J Trace Elem Med Bi PubMed
- Paiva AN, Lima JG, Medeiros AC, et al. Beneficial effects of oral chromium picolinate supplementation on glycemic control in patients with type 2 diabetes: A randomized clinical study. J Trace Elem Med Biol. 2015;32:66-72. PubMed
- Yin RV, Phung OJ. Effect of chromium supplementation on glycated hemoglobin and fasting plasma glucose in patients with diabetes mellitus. Nutr J. 2015;14:14. PubMed
- Jamilian M, Zadeh Modarres S, Amiri Siavashani M, et al. The influences of chromium supplementation on glycemic control, markers of cardio-metabolic risk, and oxidative stress in infertile polycystic ovary syndrome women candidate for in vitro fertilizati
- Alinaghi F, Thyssen JP, Zachariae C, Johansen JD. No immediate effect of regulatory reduction of chromium in leather among adult patients with chromium allergy. Contact Dermatitis 2021;85(5):514-522. PubMed
Inulin 17 references
- Williams CM. Effects of inulin on lipid parameters in humans. J Nutr 1999 Jul;129(7 Suppl):1471S-3S. PubMed
- Pedersen A, Sandstrom B, Van Amelsvoort JM. The effect of ingestion of inulin on blood lipids and gastrointestinal symptoms in healthy females. Br J Nutr 1997;78:215-22. PubMed
- Cummings JH, Macfarlane GT, Englyst HN. Prebiotic digestion and fermentation. Am J Clin Nutr 2001;73:415S-420S. PubMed
- Bonnema AL, Kolberg LW, Thomas W, Slavin JL. Gastrointestinal tolerance of chicory inulin products. J Am Diet Assoc 2010;110(6):865-8. PubMed
- Dehghan P, Gargari BP, Jafar-Abadi MA, Aliasgharzadeh A. Inulin controls inflammation and metabolic endotoxemia in women with type 2 diabetes mellitus: a randomized-controlled clinical trial. Int J Food Sci Nutr 2014;65(1):117-23. PubMed
- Guess ND, Dornhorst A, Oliver N, Frost GS. A randomised crossover trial: the effect of inulin on glucose homeostasis in subtypes of prediabetes. Ann Nutr Metab 2016;68(1):26-34. PubMed
- Marteau P, Jacobs H, Cazaubiel M, Signoret C, Prevel JM, Housez B. Effects of chicory inulin in constipated elderly people: a double-blind controlled trial. Int J Food Sci Nutr 2011;62(2):164-70. PubMed
- Mensink MA, Frijlink HW, van der Voort Maarschalk K, Hinrichs WL. Inulin, a flexible oligosaccharide I: review of its physicochemical characteristics. Carbohydr Polym 2015;130:405-19. PubMed
- Slavin J, Feirtag J. Chicory inulin does not increase stool weight or speed up intestinal transit time in healthy male subjects. Food Funct. 2011;2(1):72-7. PubMed
- Micka A, Siepelmeyer A, Holz A, Theis S, Schön C. Effect of consumption of chicory inulin on bowel function in healthy subjects with constipation: a randomized, double-blind, placebo-controlled trial. Int J Food Sci Nutr. 2017;68(1):82-89. PubMed
- Smiljanec K, Mitchell CM, Privitera OF, Neilson AP, Davy KP, Davy BM. Pre-meal inulin consumption does not affect acute energy intake in overweight and obese middle-aged and older adults: A randomized controlled crossover pilot trial. Nutr Health. 2017;23 PubMed
- Cai X, Yu H, Liu L, et al. Milk powder co-supplemented with inulin and resistant dextrin improves glycemic control and insulin resistance in elderly type 2 diabetes mellitus: a 12-week randomized, double-blind, placebo-controlled trial. Mol Nutr Food Res PubMed
- Rao M, Gao C, Xu L, et al. Effect of inulin-type carbohydrates on insulin resistance in patients with type 2 diabetes and obesity: a systematic review and meta-analysis. J Diabetes Res. 2019;2019:5101423. PubMed
- Mitchell CM, Davy BM, Ponder MA, et al. Prebiotic Inulin Supplementation and Peripheral Insulin Sensitivity in adults at Elevated Risk for Type 2 Diabetes: A Pilot Randomized Controlled Trial. Nutrients 2021;13(9):3235. PubMed
- Li L, Li P, Xu L. Assessing the effects of inulin-type fructan intake on body weight, blood glucose, and lipid profile: A systematic review and meta-analysis of randomized controlled trials. Food Sci Nutr 2021;9(8):4598-4616. PubMed
- Ziaei R, Shahshahan Z, Ghasemi-Tehrani H, Heidari Z, Ghiasvand R. Effects of inulin-type fructans with different degrees of polymerization on inflammation, oxidative stress and endothelial dysfunction in women with polycystic ovary syndrome: A randomized,
- Risso D, Kaczmarczyk M, Laurie I, et al. Moderate intakes of soluble corn fibre or inulin do not cause gastrointestinal discomfort and are well tolerated in healthy children. Int J Food Sci Nutr 2022;73(8):1104-1115. PubMed
Stevia 10 references
- Chan P, Xu DY, Liu JC, et al. The effect of stevioside on blood pressure and plasma catecholamines in spontaneously hypertensive rats. Life Sci 1998;63:1679-84. PubMed
- Melis MS. A crude extract of Stevia rebaudiana increases the renal plasma flow of normal and hypertensive rats. Braz J Med Biol Res 1996;29:669-75.
- Melis MS. Chronic administration of aqueous extract of Stevia rebaudiana in rats: renal effects. J Ethnopharmacol 1995;47:129-34. PubMed
- Melis MS, Sainati AR. Effect of calcium and verapamil on renal function of rats during treatment with stevioside. J Ethnopharmacol 1991;33:257-622. PubMed
- Hsieh MH, Chan P, Sue YM, et al. Efficacy and tolerability of oral stevioside in patients with mild essential hypertension: a two-year, randomized, placebo-controlled study. Clin Ther 2003;25:2797-808. PubMed
- Chan P, Tomlinson B, Chen YJ, et al. A double-blind placebo-controlled study of the effectiveness and tolerability of oral stevioside in human hypertension. Br J Clin Pharmacol 2000;50:215-20. PubMed
- Gregersen S, Jeppesen PB, Holst JJ, Hermansen K. Antihyperglycemic effects of stevioside in type 2 diabetic subjects. Metabolism 2004;53:73-6. PubMed
- Barriocanal LA, Palacios M, Benitez G, et al. Apparent lack of pharmacological effect of steviol glycosides used as sweeteners in humans. A pilot study of repeated exposures in some normotensive and hypotensive individuals and in Type 1 and Type 2 diabeti
- Ferri LA, Alves-Do-Prado W, Yamada SS, et al. Investigation of the antihypertensive effect of oral crude stevioside in patients with mild essential hypertension. Phytother Res 2006;20:732-6. PubMed
- Almiron-Roig E, Navas-Carretero S, Castelnuovo G, et al. Impact of acute consumption of beverages containing plant-based or alternative sweetener blends on postprandial appetite, food intake, metabolism, and gastro-intestinal symptoms: Results of the SWEE
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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