Bifido Complex Ingredients & Drug Interactions
by Kirkman
What is this page for?
First and foremost: checking Bifido Complex against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Bifido Complex is a dietary supplement by Kirkman with 4 active ingredients. Its ingredients are commonly taken for digestive health and regularity, irritable bowel syndrome (ibs), diarrhea (including antibiotic-related).Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bifidobacterium longum, Bifidobacterium bifidum, Bifidobacterium breve. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Bifido Complex by Kirkman
Ask about any prescription or over-the-counter medication and we check it for interactions with Bifido Complex by Kirkman — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Bifido Complex by Kirkman
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Bifido Complex contains four live probiotic bacteria species: Bifidobacterium longum, Bifidobacterium bifidum, Bifidobacterium breve, and Bifidobacterium animalis lactis. These are "friendly" bacteria meant to support your gut health.
The capsule itself is made from hypromellose (a plant-based coating), microcrystalline cellulose, silicon dioxide, and water—all inactive ingredients that help hold the product together.
Does it work?
Moderate evidence
The evidence for what these probiotics actually do is mixed. Bifidobacterium bifidum shows possibly effective evidence for irritable bowel syndrome (IBS) and respiratory tract infections.
Bifidobacterium breve, on the other hand, is rated possibly ineffective for age-related cognitive decline and sepsis. For the other conditions listed—hay fever, anxiety, asthma, antibiotic-associated diarrhea, Alzheimer's disease—we don't have enough reliable evidence to say whether these bacteria help or not.
Data for the other two ingredients isn't established in our records.
How safe is it?
Well-documented data
These bacteria are generally well tolerated in healthy people, but caution is warranted if you're seriously ill or have a weakened immune system—talk to your doctor first. Rare side effects from the checked ingredients include abdominal discomfort, bloating, flatulence, constipation, and a dry cough.
Very rarely, in critically ill or premature infants, Bifidobacterium species have caused serious bloodstream infections (bacteremia); this is extremely uncommon in otherwise healthy adults. For pregnancy and breastfeeding, Bifidobacterium longum is rated possibly safe for both, and Bifidobacterium bifidum is rated possibly safe during pregnancy—but data on breastfeeding for bifidum isn't on file.
Because safety data are limited overall, check with your doctor before use, especially if you're pregnant, breastfeeding, or seriously ill.
Meds to double-check
Moderate interaction found
Antibiotic drugs are the main one to watch. Because these are live bacteria, antibiotics will kill them and make this probiotic less effective.
Space your antibiotic doses at least a few hours away from this product—ask your pharmacist for a dosing schedule that works.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
If you have IBS or recurring respiratory infections and you're in good health, this probiotic blend is worth discussing with your pharmacist. Skip it if you're taking antibiotics right now—space them several hours apart instead.
If you're seriously ill, immune-compromised, pregnant, or breastfeeding, get your doctor's okay first.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Bifido Complex, straight from the product label.
| Brand | Kirkman |
|---|---|
| Barcode (UPC) | 812325021925 |
| Net contents | 60 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Sep 25, 2023 |
| DSLD ID | 296951 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Bifido Complex by Kirkman, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Bifidobacterium longum | 0 NP | -- |
| Bifidobacterium bifidum | 0 NP | -- |
| Bifidobacterium animalis lactis | 0 NP | -- |
| Bifidobacterium breve | 0 NP | -- |
| Kirkman Proprietary Probiotic Blend | 75 mg | -- |
Other ingredients: Hypromellose, Water, Microcrystalline Cellulose, Silicon Dioxide
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Storage
Important: Keep bottle refrigerated and tightly capped.
Do not remove the desiccant bag or oxygen absorber if present.
Precautions
Keep out of the reach of children.
Formulation
Free of: milk, eggs, fish, shellfish, tree nuts, peanuts, wheat or soy
Gluten-free
Seals/Symbols
Ultra tested
cGMP Good Manufacturing Products Consistent Quality
Formula
15 billion CFUs
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Suggested use: One to two capsules daily or as directed by a physician.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Bifido Complex by Kirkman label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Bifido Complex by Kirkman
These are the 4 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Kirkman Proprietary Probiotic Blend
- › Bifidobacterium longum
- › Bifidobacterium bifidum
- › Bifidobacterium animalis lactis
- › Bifidobacterium breve
Other (inactive) ingredients: Hypromellose, Water, Microcrystalline Cellulose, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.
Bifido Complex by Kirkman Drug Interactions
HelloPharmacist Interaction Report
Bifido Complex by Kirkman contains four Bifidobacterium species, and the ones we could check do interact with one medication type: antibiotics.
All three checked ingredients—Bifidobacterium longum, Bifidobacterium bifidum, and Bifidobacterium breve—carry a Moderate interaction with antibiotic drugs. Since these are live organisms, antibiotics can kill them off and reduce their effectiveness.
The fix is simple: space out your doses. Take your antibiotic at a different time than this probiotic, ideally a few hours apart.
Read the full breakdown — every affected drug type, severity by severity
Additionally, we couldn't check Bifidobacterium animalis lactis—we hold no interaction data for that ingredient. Altogether, these interactions span 182 individual medications.
Use the medication checker below to look up your exact antibiotic before you start this product, and let your pharmacist know the timing so we can help you separate them properly.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Bifido Complex?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Bifido Complex interact with 182 drugs. Click any drug to see the details.
3 of the 4 ingredients in Bifido Complex interact with drugs. Each result below shows which ingredient is responsible. Bifidobacterium longum Bifidobacterium bifidum Bifidobacterium breve
AmikacinAmikin, Arikayce
How Amikacin interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Amikacin interactionBifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Amikacin interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Amikacin interactionAmoxicillinAmix, Amoram, Amoxident, Amoxil Capsules, Amoxil Injection, Galenamox +3 more
How Amoxicillin interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Amoxicillin interactionBifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Amoxicillin interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Amoxicillin interactionAmoxicillin VeterinaryBiomox
How Amoxicillin Veterinary interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Amoxicillin Veterinary interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Amoxicillin Veterinary interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Amoxicillin Veterinary interactionAmoxicillin, Clavulanate PotassiumAugmentin, Augmentin '125/31 SF', Augmentin '250/62 SF', Augmentin XR, Augmentin-Duo 400/57, Clavulin
How Amoxicillin, Clavulanate Potassium interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Amoxicillin, Clavulanate Potassium interactionBifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Amoxicillin, Clavulanate Potassium interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Amoxicillin, Clavulanate Potassium interactionAmoxicillin, Omeprazole Magnesium, RifabutinTalicia
How Amoxicillin, Omeprazole Magnesium, Rifabutin interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Amoxicillin, Omeprazole Magnesium, Rifabutin interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Amoxicillin, Omeprazole Magnesium, Rifabutin interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Amoxicillin, Omeprazole Magnesium, Rifabutin interactionAmphotericin, TetracyclineMysteclin-F
How Amphotericin, Tetracycline interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Amphotericin, Tetracycline interactionBifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Amphotericin, Tetracycline interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Amphotericin, Tetracycline interactionAmpicillinOmnipen, Omnipen-N, Penbritin, Principen, Rimacillin
How Ampicillin interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Ampicillin interactionBifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Ampicillin interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Ampicillin interactionAmpicillin, SulbactamUnasyn
How Ampicillin, Sulbactam interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Ampicillin, Sulbactam interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Ampicillin, Sulbactam interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Ampicillin, Sulbactam interactionAvibactam Sodium, CeftazidimeAvycaz
How Avibactam Sodium, Ceftazidime interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Avibactam Sodium, Ceftazidime interactionBifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Avibactam Sodium, Ceftazidime interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Avibactam Sodium, Ceftazidime interactionAzithromycinAzasite, Zithromax, Zmax
How Azithromycin interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Azithromycin interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Azithromycin interactionBifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Azithromycin interactionAztreonamAzactam
How Aztreonam interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Aztreonam interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Aztreonam interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Aztreonam interactionBacampicillinPenglobe
How Bacampicillin interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Bacampicillin interactionBifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Bacampicillin interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Bacampicillin interactionBacitracinBaci-IM, Baciguent, Bacitracin Ointment
How Bacitracin interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Bacitracin interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Bacitracin interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Bacitracin interactionBenznidazoleBenznidazole
How Benznidazole interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Benznidazole interactionBifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Benznidazole interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Benznidazole interactionBismuth Subsalicylate, Metronidazole, TetracyclineHelidac
How Bismuth Subsalicylate, Metronidazole, Tetracycline interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Bismuth Subsalicylate, Metronidazole, Tetracycline interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Bismuth Subsalicylate, Metronidazole, Tetracycline interactionBifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Bismuth Subsalicylate, Metronidazole, Tetracycline interactionCapreomycinCapastat
How Capreomycin interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Capreomycin interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Capreomycin interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Capreomycin interactionCarbenicillin Indanyl SodiumGeocillin
How Carbenicillin Indanyl Sodium interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Carbenicillin Indanyl Sodium interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Carbenicillin Indanyl Sodium interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Carbenicillin Indanyl Sodium interactionCefaclorCeclor, Ceclor CD
How Cefaclor interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Cefaclor interactionBifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Cefaclor interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Cefaclor interactionCefadroxilCef-Tab, Duricef, Ultracef
How Cefadroxil interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Cefadroxil interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Cefadroxil interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Cefadroxil interactionCefamandoleMandol
How Cefamandole interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Cefamandole interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Cefamandole interactionBifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Cefamandole interactionCefazolinAncef
How Cefazolin interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Cefazolin interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Cefazolin interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Cefazolin interactionCefdinirOmnicef
How Cefdinir interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Cefdinir interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Cefdinir interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Cefdinir interactionCefditoren PivoxilSpectracef
How Cefditoren Pivoxil interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Cefditoren Pivoxil interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Cefditoren Pivoxil interactionBifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Cefditoren Pivoxil interactionCefepimeMaxipime
How Cefepime interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Cefepime interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Cefepime interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Cefepime interactionCefiderocol Sulfate TosylateFetroja
How Cefiderocol Sulfate Tosylate interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Cefiderocol Sulfate Tosylate interactionBifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Cefiderocol Sulfate Tosylate interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Cefiderocol Sulfate Tosylate interactionCefiximeSuprax
How Cefixime interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Cefixime interactionBifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Cefixime interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Cefixime interactionCefmetazoleZefazone
How Cefmetazole interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Cefmetazole interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Cefmetazole interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Cefmetazole interactionCefonicidMonocid
How Cefonicid interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Cefonicid interactionBifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Cefonicid interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Cefonicid interactionCefoperazoneCefobid
How Cefoperazone interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Cefoperazone interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Cefoperazone interactionBifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Cefoperazone interactionCefotaximeClaforan
How Cefotaxime interacts with Bifido Complex — through 3 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Cefotaxime interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Cefotaxime interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Cefotaxime interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Bifido Complex with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Bifidobacterium longum
Antibiotic Drugs
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B. longum.
Since B. longum preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. longum preparations by at least 2 hours.
Bifidobacterium bifidum
Antibiotic Drugs
Theoretically, taking Bifidobacterium. bifidum with antibiotic drugs might decrease the effectiveness of B. bifidum.
Since B. bifidum preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. bifidum preparations by at least 2 hours.
Bifidobacterium breve
Antibiotic Drugs
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B. breve.
Since B. breve preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. breve preparations by at least 2 hours.
Brand information
Manufacturer and brand details for Bifido Complex, from the product label.
Kirkman
See all Kirkman products- Name
- Kirkman
- City
- Lake Oswego
- State
- OR
- ZipCode
- 97035
- Phone Number
- 503.694.1600 1.800.245.8282
- Web Address
- kirkmangroup.com
Bifido Complex by Kirkman: Common Questions
Does Bifido Complex by Kirkman interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
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What does this probiotic actually do?
What if I have a weak immune system—is it safe for me?
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Can I take this while breastfeeding?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Bifido Complex is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Bifido Complex’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Bifidobacterium Longum
Interacts with 182 drugsBifidobacterium longum is a 'friendly' bacterium found naturally in the human gut and used as a probiotic. It is generally well tolerated and is most studied for digestive issues, though evi...
Read the full Bifidobacterium Longum monograph → Herb & supplement monographBifidobacterium Bifidum
Interacts with 182 drugsBifidobacterium bifidum is a 'friendly' bacteria (probiotic) that naturally lives in the human gut and is taken to support digestion and gut balance. Some evidence suggests probiotics may he...
Read the full Bifidobacterium Bifidum monograph → Herb & supplement monographBifidobacterium Breve
Interacts with 182 drugsBifidobacterium breve is a 'friendly' gut bacterium taken as a probiotic, most often to support digestion and balance the gut microbiome. Some studies suggest possible benefits for certain d...
Read the full Bifidobacterium Breve monograph →Sources & How We Checked
Bifido Complex's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 37 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Bifidobacterium Longum 21 references
- Ha GY, Yang CH, Kim H, Chong Y. Case of sepsis caused by Bifidobacterium longum. J Clin Microbiol 1999;37:1227-8.
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
- Rautava S, Kainonen E, Salminen S, Isolauri E. Maternal probiotic supplementation during pregnancy and breast-feeding reduces the risk of eczema in the infant. J Allergy Clin Immunol. 2012;130(6):1355-60. PubMed
- Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
- Pellonperä O, Vahlberg T, Mokkala K, et al. Weight gain and body composition during pregnancy: a randomised pilot trial with probiotics and/or fish oil. Br J Nutr. 2020 Nov 4:1-11. PubMed
- Pellonperä O, Mokkala K, Houttu N, et al. Efficacy of fish oil and/or probiotic intervention on the incidence of gestational diabetes mellitus in an at-risk group of overweight and obese women: A randomized, placebo-controlled, double-blind clinical trial PubMed
- Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
- Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed
- Enomoto T, Sowa M, Nishimori K, et al. Effects of bifidobacterial supplementation to pregnant women and infants in the prevention of allergy development in infants and on fecal microbiota. Allergol Int 2014;63(4):575-85. PubMed
- US Food and Drug Administration (FDA). Dear Healthcare Provider Letter: Warning Regarding Use of Probiotics in Preterm Infants. September 2023. Available at: https://www.fda.gov/media/172606/download?attachment. Accessed November 1, 2023.
- Pillai A, Tan J, Paquette V, Panczuk J. Does probiotic bacteremia in premature infants impact clinically relevant outcomes? A case report and updated review of literature. Clin Nutr ESPEN. 2020;39:255-259. PubMed
- Sabaté JM, Iglicki F. Effect of Bifidobacterium longum 35624 on disease severity and quality of life in patients with irritable bowel syndrome. World J Gastroenterol 2022;28(7):732-744.
- Malaguarnera M, Greco F, Barone G, Gargante MP, Malaguarnera M, Toscano MA. Bifidobacterium longum with fructo-oligosaccharide (FOS) treatment in minimal hepatic encephalopathy: a randomized, double-blind, placebo-controlled study. Dig Dis Sci 2007;52(11) PubMed
- Zbinden A, Zbinden R, Berger C, Arlettaz R. Case series of Bifidobacterium longum bacteremia in three preterm infants on probiotic therapy. Neonatology 2015;107(1):56-9.
- Tamaki H, Nakase H, Inoue S, et al. Efficacy of probiotic treatment with Bifidobacterium longum 536 for induction of remission in active ulcerative colitis: A randomized, double-blinded, placebo-controlled multicenter trial. Dig Endosc 2016;28(1):67-74.
- Bertelli C, Pillonel T, Torregrossa A, et al. Bifidobacterium longum bacteremia in preterm infants receiving probiotics. Clin Infect Dis 2015;60(6):924-7. PubMed
- Esaiassen E, Cavanagh P, Hjerde E, Simonsen GS, Støen R, Klingenberg C. Bifidobacterium longum subspecies infantis bacteremia in 3 extremely preterm infants receiving probiotics. Emerg Infect Dis 2016;22(9):1664-6.
- Tena D, Losa C, Medina MJ, Sáez-Nieto JA. Peritonitis caused by Bifidobacterium longum: case report and literature review. Anaerobe 2014;27:27-30. PubMed
- Sangkanjanavanich S, Pradubpongsa P, Mitthamsiri W, Sangasapaviliya A, Boonpiyathad T. Bifidobacterium infantis 35624 efficacy in patients with uncontrolled asthma: A randomized placebo-controlled trial. Ann Allergy Asthma Immunol 2022;129(6):790-792. PubMed
- Wilson HL, Ong CW. Bifidobacterium longum vertebrodiscitis in a patient with cirrhosis and prostate cancer. Anaerobe 2017;47:47-50. PubMed
See these in context on the Bifidobacterium Longum monograph →
Bifidobacterium Bifidum 7 references
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
- Rerksuppaphol S, Rerksuppaphol L. Randomized controlled trial of probiotics to reduce common cold in schoolchildren. Pediatr Int. 2012;54(5):682-7. PubMed
- Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
- Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
- Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
- Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed
See these in context on the Bifidobacterium Bifidum monograph →
Bifidobacterium Breve 9 references
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
- Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
- Ohishi A, Takahashi S, Ito Y, et al. Bifidobacterium septicemia associated with postoperative probiotic therapy in a neonate with omphalocele. J Pediatr. 2010;156(4):679-81. PubMed
- Sakurai Y, Watanabe T, Miura Y, et al. Clinical and bacteriologic characteristics of six cases of Bifidobacterium breve bacteremia due to probiotic administration in the neonatal intensive care unit. Pediatr Infect Dis J 2022;41(1):62-65. PubMed
- Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed
- Wakabayashi Y, Nakayama S, Yamamoto A, et al. First case of necrotizing fasciitis and bacteremia caused by Bifidobacteriumbreve. Anaerobe 2022;76:102613.
- Takeda Y, Ota K, Kondo A, et al. A case of necrotizing fasciitis caused by Bifidobacterium breve. IDCases 2022;31:e01667. PubMed
- Suwantarat N, Romagnoli M, Wakefield T, Carroll KC. Ventriculoperitoneal shunt infection caused by Bifidobacterium breve. Anaerobe 2014;28:1-3. PubMed
See these in context on the Bifidobacterium Breve monograph →
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC