Interactions on record — worth a quick check against your medications. Based on 2 of 7 ingredients. Check your meds →
Dietary supplement

Bio.Me Femme UT Ingredients & Drug Interactions

by Invivo

Powder Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Bio.Me Femme UT is a dietary supplement by Invivo with 7 active ingredients. Its ingredients are commonly taken for digestive health and balance, diarrhea (including antibiotic-related), vaginal yeast and bacterial infections.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are L. acidophilus W22, Lactobacillus helveticus W74. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Bio.Me Femme UT by Invivo

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 7 active ingredients.
  • “Winclove Clear Probiotics” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.

Bio.Me Femme UT contains 7 active probiotic ingredients — five different Lactobacillus strains plus L. acidophilus W22 and Lactobacillus helveticus W74 — packaged as a proprietary blend called Winclove Clear Probiotics. Probiotics are live beneficial bacteria intended to support urinary tract and gut health.

The product also contains one inactive ingredient (PROBIOACT) as a carrier or stabilizer.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Clinically researched probiotics for urinary microbiome health.
  • We looked for evidence on: Urinary tract infections (UTIs), Bacterial vaginosis, Vaginal candidiasis, Urinary microbiome balance, Uropathogens, Recurrent UTI prevention.
  • The strongest evidence on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Bacterial vaginosis (Natural Medicines).
  • Also on file: Lactobacillus Acidophilus is rated "Insufficient Reliable Evidence To Rate" for Urinary tract infections (UTIs), Vaginal candidiasis.

The evidence for most of these strains is limited. L. acidophilus is possibly effective for irritable bowel syndrome, Helicobacter pylori, antibiotic-associated diarrhea, and bacterial vaginosis.

Lactobacillus helveticus has insufficient reliable evidence to rate for any condition in our data — which includes hay fever, antibiotic-associated diarrhea, cognitive function, depression, rotaviral diarrhea, and exercise-induced respiratory infections. For the other four strains in the blend, we hold no effectiveness ratings.

The evidence, ingredient by ingredient Lactobacillus Acidophilus Lactobacillus Helveticus

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L. acidophilus is generally well tolerated in healthy adults and children, though you should check with your doctor before use. Lactobacillus helveticus is also generally well tolerated in healthy people, but if you're seriously ill or immunocompromised, be cautious — and use it only with your doctor's guidance since safety data are limited.

Both ingredients are live microorganisms, so there's a theoretical concern they could cause infection in some patients, especially those with weakened immunity. Orally, L. acidophilus in combination with other probiotics may cause uncommon gastrointestinal side effects like bloating, flatulence, stomach discomfort, or diarrhea.

One clinical trial involving a multi-strain probiotic found two cases of rash and one case of itching, though it's unclear whether L. acidophilus was responsible.

Side effects, ingredient by ingredient Lactobacillus Acidophilus Lactobacillus Helveticus

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Lactobacillus Acidophilus, Lactobacillus Helveticus.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before starting Bio.Me Femme UT, double-check any antibiotic drugs you're taking (Moderate severity). Because the probiotics in this product are live organisms, antibiotics taken at the same time could kill them off and reduce their benefit — spacing out the timing can help.

No other medication interactions are documented for the strains we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product is designed for urinary tract and digestive health using live probiotic strains. If you take antibiotics, separate them from this product — antibiotics can kill the beneficial bacteria and make the probiotic less effective.

If you're immunocompromised or seriously ill, talk with your doctor before starting. Check your specific medications with the tool on this page.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 7 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Bio.Me Femme UT, straight from the product label.

Brand Invivo
Barcode (UPC) 0710535365924
Net contents 90 Gram(s)
Market status On market
Date entered into DSLD Feb 23, 2022
DSLD ID 259862
Product type Non-nutrient/non-botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Bio.Me Femme UT by Invivo, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Gram(s)
Maximum serving Sizes:
3 Gram(s)
UPC/BARCODE
0710535365924
IngredientAmount% DV
Winclove Clear Probiotics0 NP--
L. pentosus W2 (KCA1)0 NP--
L. acidophilus W220 NP--
L. brevis W630 NP--
L. casei W560 NP--
Lactobacillus helveticus W740 NP--
L. plantarum W210 NP--
L. salivarius W240 NP--

Other ingredients: PROBIOACT

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Food Supplement

Formulation

Clinically researched probiotics for the urinary microbiome

GMO-free Gluten-free

Vegetarian

Storage

Shelf-stable

Store in the original packaging, at room temperature, in a dry place.

Suggested/Recommended/Usage/Directions

Directions: Mix 3g (1.5 tsp) daily into 100ml of water. Leave for 1 minute. Stir and take on an empty stomach.

Precautions

Do not exceed the recommended dose, unless advised by your healthcare professional.

Do not use if immunocompromised or allergic to any of the ingredients.

When taking antibiotics, wait 2-3 hours before using Bio.Me Femme UT.

Food supplements are not a substitute for a varied and balanced diet or lifestyle.

Keep out of reach of children.

Allergens: May contain traces of soy

Seals/Symbols

Certified B Corporation

Carbon Neutral

GMP Certified

Probioact Technology

See for yourself

Bio.Me Femme UT by Invivo label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Bio.Me Femme UT by Invivo

These are the 7 active ingredients this product is made of. Select any to open its full monograph.

Serving size3 Gram(s) Dosage formPowder Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Winclove Clear Probiotics

0 NP per serving

Other (inactive) ingredients: PROBIOACT. These complete the product’s ingredient list but are not active constituents.

Interaction report

Bio.Me Femme UT by Invivo Drug Interactions

Want to check YOUR meds against Bio.Me Femme UT?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Bio.Me Femme UT with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

L. acidophilus W221 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.

Likelihood Probable Evidence D

Lactobacillus helveticus W741 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus helveticus with antibiotic drugs might decrease the effectiveness of L. helveticus.
Lactobacillus helveticus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. helveticus preparations by at least two hours.

Likelihood Probable Evidence D
The maker

Brand information

Manufacturer and brand details for Bio.Me Femme UT, from the product label.

Invivo

See all Invivo products
Name
Invivo Healthcare
State
UK
ZipCode
GL5 2TE
Web Address
invivohealthcare.com
Pharmacist Counseling Corner

Bio.Me Femme UT by Invivo: Common Questions

Does Bio.Me Femme UT by Invivo interact with any medications?
Yes. Based on its ingredients, Bio.Me Femme UT has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Bio.Me Femme UT contains 7 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this with my antibiotics?
Yes, but timing matters. Antibiotics can kill the live bacteria in this probiotic, making it less effective. Separate the two by a few hours — your pharmacist can help you work out the best schedule for your specific antibiotic.
Is this safe if I'm pregnant or breastfeeding?
L. acidophilus is rated as possibly safe in pregnancy, but we don't have pregnancy or lactation data for most of the other strains in this blend. Talk with your doctor or pharmacist about whether this product is right for you during pregnancy or while breastfeeding.
What side effects might I experience?
Most people tolerate it well. Uncommonly, you might experience mild gastrointestinal effects like bloating, gas, stomach discomfort, or diarrhea, especially when you first start. One clinical trial found a few cases of rash or itching, though it's unclear if those were caused by this type of probiotic.
Does this really help with urinary tract health?
The evidence is limited. L. acidophilus is possibly effective for bacterial vaginosis and some other conditions, but most of the strains in this blend don't have established effectiveness data in our records. Your results may vary.
Am I getting live bacteria or dead ones?
These are live, active organisms — that's what makes them probiotics. Because they're live, they work differently from other supplements, which is why timing with antibiotics matters and why immunocompromised people should check with their doctor first.
What are all these Lactobacillus strains doing in one product?
They're combined in a blend called Winclove Clear Probiotics. The idea is that different bacterial strains may work together to support your gut and urinary tract health, though the evidence for this specific combination is limited.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Bio.Me Femme UT is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Bio.Me Femme UT label
Sources

Sources & How We Checked

Bio.Me Femme UT's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 17 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lactobacillus Acidophilus 15 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
  3. Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
  4. Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
  5. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  6. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  7. Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
  10. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  11. Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
  12. Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
  13. Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
  14. Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
  15. Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.

See these in context on the Lactobacillus Acidophilus monograph →

Lactobacillus Helveticus 2 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed

See these in context on the Lactobacillus Helveticus monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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