Bio.Me Oral Ingredients & Drug Interactions
by Invivo
What is this page for?
First and foremost: checking Bio.Me Oral against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Bio.Me Oral is a dietary supplement by Invivo with 9 active ingredients. Its ingredients are commonly taken for digestive health and regularity, diarrhea (including antibiotic-related), irritable bowel syndrome (ibs) symptoms.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bifidobacterium bifidum W23, B. breve W25. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Bio.Me Oral by Invivo
Ask about any prescription or over-the-counter medication and we check it for interactions with Bio.Me Oral by Invivo — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Bio.Me Oral by Invivo
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Bio.Me Oral contains nine active ingredients, all probiotic (beneficial bacteria) strains: Bifidobacterium bifidum W23, B. lactis W51, Lactobacillus salivarius W24, L. plantarum W21, Enterococcus faecium W54, L. rhamnosus W71, L. salivarius W57, Streptococcus thermophilus W69, and B. breve W25. These are meant to support your gut bacteria balance.
The powder also contains three inactive ingredients — maize starch, maltodextrin, and hydrolyzed rice protein — which help make the formulation stable.
Does it work?
Not established
The evidence on what these ingredients can do is mixed. B. bifidum is possibly effective for irritable bowel syndrome (IBS) and respiratory tract infections, but we don't have enough data to rate it for hay fever, Alzheimer disease, or anxiety.
B. breve is rated possibly ineffective for age-related cognitive decline and sepsis, and insufficient evidence exists for hay fever, antibiotic-associated diarrhea, or atopic disease. Streptococcus thermophilus has insufficient evidence for antibiotic-associated diarrhea, bacterial vaginosis, fatty liver disease, constipation, diabetes, or diabetic kidney disease.
For the other strains, we hold no effectiveness ratings in our data.
How safe is it?
Well-documented data
These probiotics are generally well tolerated in healthy people. The main caution: if you have a weakened immune system or are severely ill, check with your doctor before taking this product — rare cases of blood infection (bacteremia) and sepsis have been reported in critically ill or immunocompromised patients, though these are uncommon and haven't been tied specifically to most of these strains.
Bloating and flatulence can occur with probiotics in general, though they haven't been reported specifically from B. bifidum or B. breve. One case of vomiting and fever was reported in a child taking B. bifidum with another probiotic, but it's unclear whether the probiotics caused it.
Pregnancy: B. bifidum and S. thermophilus are rated possibly safe in pregnancy. For B. breve, pregnancy and lactation data aren't on file.
Talk to your doctor before use during pregnancy or breastfeeding.
Meds to double-check
Moderate interaction found
If you're taking antibiotics, separate your dose from this product by a few hours — the probiotics can be killed off if taken together, lowering how well they work. For the five other probiotic strains in this product, we don't hold interaction data, so ask your pharmacist to check those against your specific medications if you take anything else.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
Bio.Me Oral is a multi-strain probiotic that may help with IBS and respiratory infections, though the evidence for many of its uses is still limited. If you take antibiotics, just space this product a few hours apart from your dose.
Anyone with a severely weakened immune system should check with their doctor first. Ask your pharmacist or doctor about whether this fits your needs.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 9 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2022.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Bio.Me Oral, straight from the product label.
| Brand | Invivo |
|---|---|
| Barcode (UPC) | 0710535365955 |
| Net contents | 60 Gram(s) |
| Market status | On market |
| Date entered into DSLD | Feb 23, 2022 |
| DSLD ID | 259865 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Powder |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegetarian, Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Bio.Me Oral by Invivo, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Bifidobacterium bifidum W23 | 0 NP | -- |
| Bifidobacterium lactis W51 | 0 NP | -- |
| Lactobacillus salivarius W24 | 0 NP | -- |
| Lactobacillus plantarum W21 | 0 NP | -- |
| Enterococcus faecium W54 | 0 NP | -- |
| Lactobacillus rhamnosus W71 | 0 NP | -- |
| Lactobacillus salivarius W57 | 0 NP | -- |
| Streptococcus thermophilus W69 | 0 NP | -- |
| Smile Probiotics | 0 NP | -- |
| B. breve W25 | 0 NP | -- |
Other ingredients: Maize Starch, Maltodextrin, hydrolyzed Rice Protein
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity
Food Supplement
Formulation
Mouthwash with clinically researched probiotics for the oral microbiome
GMO-free
Vegetarian
Storage
Shelf-stable
Store in the original packaging, at room temperature, in a dry place.
Suggested/Recommended/Usage/Directions
Directions: Mix 1g (0.5 tsp) twice daily into 50ml of water. Leave for 1 minute. Stir before swishing in the mouth for 20 seconds before swallowing or spitting out.
Precautions
Do not exceed the recommended dose, unless advised by your healthcare professional.
Do not use if immunocompromised or allergic to any of the ingredients.
When taking antibiotics, wait 2-3 hours before using Bio.Me Oral.
Food supplements are not a substitute for a varied and balanced diet or lifestyle.
Keep out of reach of children.
Seals/Symbols
Certified B Corporation
Carbon Neutral
Probioact Technology
GMP Certified
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Bio.Me Oral by Invivo label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Bio.Me Oral by Invivo
These are the 9 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Gram(s) Dosage formPowder Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Smile Probiotics
- › Bifidobacterium bifidum W23
- › Bifidobacterium lactis W51
- › Lactobacillus salivarius W24
- › Lactobacillus plantarum W21
- › Enterococcus faecium W54
- › Lactobacillus rhamnosus W71
- › Lactobacillus salivarius W57
- › Streptococcus thermophilus W69
- › B. breve W25
Other (inactive) ingredients: Maize Starch, Maltodextrin, Hydrolyzed Rice Protein. These complete the product’s ingredient list but are not active constituents.
Bio.Me Oral by Invivo Drug Interactions
HelloPharmacist Interaction Report
Bio.Me Oral by Invivo is a probiotic powder that does interact with one major medication category.
Bifidobacterium bifidum and B. breve, two of the active ingredients, both interact with antibiotic drugs (Moderate severity). Since these probiotics contain live organisms, taking them at the same time as antibiotics might kill off a significant portion of the probiotic cells and reduce their effectiveness.
The solution is simple: space out your antibiotic and this probiotic by a few hours.
Read the full breakdown — every affected drug type, severity by severity
Additionally, no interactions are documented for the other five probiotic strains in this product — we could not check interaction data for Bifidobacterium lactis W51, Lactobacillus salivarius W24, Lactobacillus plantarum W21, Enterococcus faecium W54, Lactobacillus rhamnosus W71, and Lactobacillus salivarius W57. Streptococcus thermophilus, the eighth active ingredient, was checked and shows no known interactions.
Altogether, these interactions span 182 individual medications. If you're on an antibiotic, run it through the interaction checker on this page before you start Bio.Me Oral.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Bio.Me Oral?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Bio.Me Oral interact with 182 drugs. Click any drug to see the details.
2 of the 9 ingredients in Bio.Me Oral interact with drugs. Each result below shows which ingredient is responsible. Bifidobacterium bifidum W23 B. breve W25
AmikacinAmikin, Arikayce
How Amikacin interacts with Bio.Me Oral — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Bifidum W23Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum W23 + Amikacin interactionB. Breve W25Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve W25 + Amikacin interactionAmoxicillinAmix, Amoram, Amoxident, Amoxil Capsules, Amoxil Injection, Galenamox +3 more
How Amoxicillin interacts with Bio.Me Oral — through 2 ingredients. Tap an ingredient for the detail:
B. Breve W25Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve W25 + Amoxicillin interactionBifidobacterium Bifidum W23Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum W23 + Amoxicillin interactionAmoxicillin VeterinaryBiomox
How Amoxicillin Veterinary interacts with Bio.Me Oral — through 2 ingredients. Tap an ingredient for the detail:
B. Breve W25Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve W25 + Amoxicillin Veterinary interactionBifidobacterium Bifidum W23Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum W23 + Amoxicillin Veterinary interactionAmoxicillin, Clavulanate PotassiumAugmentin, Augmentin '125/31 SF', Augmentin '250/62 SF', Augmentin XR, Augmentin-Duo 400/57, Clavulin
How Amoxicillin, Clavulanate Potassium interacts with Bio.Me Oral — through 2 ingredients. Tap an ingredient for the detail:
B. Breve W25Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve W25 + Amoxicillin, Clavulanate Potassium interactionBifidobacterium Bifidum W23Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum W23 + Amoxicillin, Clavulanate Potassium interactionAmoxicillin, Omeprazole Magnesium, RifabutinTalicia
How Amoxicillin, Omeprazole Magnesium, Rifabutin interacts with Bio.Me Oral — through 2 ingredients. Tap an ingredient for the detail:
B. Breve W25Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve W25 + Amoxicillin, Omeprazole Magnesium, Rifabutin interactionBifidobacterium Bifidum W23Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum W23 + Amoxicillin, Omeprazole Magnesium, Rifabutin interactionAmphotericin, TetracyclineMysteclin-F
How Amphotericin, Tetracycline interacts with Bio.Me Oral — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Bifidum W23Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum W23 + Amphotericin, Tetracycline interactionB. Breve W25Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve W25 + Amphotericin, Tetracycline interactionAmpicillinOmnipen, Omnipen-N, Penbritin, Principen, Rimacillin
How Ampicillin interacts with Bio.Me Oral — through 2 ingredients. Tap an ingredient for the detail:
B. Breve W25Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve W25 + Ampicillin interactionBifidobacterium Bifidum W23Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum W23 + Ampicillin interactionAmpicillin, SulbactamUnasyn
How Ampicillin, Sulbactam interacts with Bio.Me Oral — through 2 ingredients. Tap an ingredient for the detail:
B. Breve W25Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve W25 + Ampicillin, Sulbactam interactionBifidobacterium Bifidum W23Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum W23 + Ampicillin, Sulbactam interactionAvibactam Sodium, CeftazidimeAvycaz
How Avibactam Sodium, Ceftazidime interacts with Bio.Me Oral — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Bifidum W23Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum W23 + Avibactam Sodium, Ceftazidime interactionB. Breve W25Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve W25 + Avibactam Sodium, Ceftazidime interactionAzithromycinAzasite, Zithromax, Zmax
How Azithromycin interacts with Bio.Me Oral — through 2 ingredients. Tap an ingredient for the detail:
B. Breve W25Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve W25 + Azithromycin interactionBifidobacterium Bifidum W23Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum W23 + Azithromycin interactionAztreonamAzactam
How Aztreonam interacts with Bio.Me Oral — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Bifidum W23Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum W23 + Aztreonam interactionB. Breve W25Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve W25 + Aztreonam interactionBacampicillinPenglobe
How Bacampicillin interacts with Bio.Me Oral — through 2 ingredients. Tap an ingredient for the detail:
B. Breve W25Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve W25 + Bacampicillin interactionBifidobacterium Bifidum W23Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum W23 + Bacampicillin interactionBacitracinBaci-IM, Baciguent, Bacitracin Ointment
How Bacitracin interacts with Bio.Me Oral — through 2 ingredients. Tap an ingredient for the detail:
B. Breve W25Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve W25 + Bacitracin interactionBifidobacterium Bifidum W23Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum W23 + Bacitracin interactionBenznidazoleBenznidazole
How Benznidazole interacts with Bio.Me Oral — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Bifidum W23Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum W23 + Benznidazole interactionB. Breve W25Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve W25 + Benznidazole interactionBismuth Subsalicylate, Metronidazole, TetracyclineHelidac
How Bismuth Subsalicylate, Metronidazole, Tetracycline interacts with Bio.Me Oral — through 2 ingredients. Tap an ingredient for the detail:
B. Breve W25Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve W25 + Bismuth Subsalicylate, Metronidazole, Tetracycline interactionBifidobacterium Bifidum W23Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum W23 + Bismuth Subsalicylate, Metronidazole, Tetracycline interactionCapreomycinCapastat
How Capreomycin interacts with Bio.Me Oral — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Bifidum W23Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum W23 + Capreomycin interactionB. Breve W25Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve W25 + Capreomycin interactionCarbenicillin Indanyl SodiumGeocillin
How Carbenicillin Indanyl Sodium interacts with Bio.Me Oral — through 2 ingredients. Tap an ingredient for the detail:
B. Breve W25Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve W25 + Carbenicillin Indanyl Sodium interactionBifidobacterium Bifidum W23Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum W23 + Carbenicillin Indanyl Sodium interactionCefaclorCeclor, Ceclor CD
How Cefaclor interacts with Bio.Me Oral — through 2 ingredients. Tap an ingredient for the detail:
B. Breve W25Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve W25 + Cefaclor interactionBifidobacterium Bifidum W23Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum W23 + Cefaclor interactionCefadroxilCef-Tab, Duricef, Ultracef
How Cefadroxil interacts with Bio.Me Oral — through 2 ingredients. Tap an ingredient for the detail:
B. Breve W25Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve W25 + Cefadroxil interactionBifidobacterium Bifidum W23Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum W23 + Cefadroxil interactionCefamandoleMandol
How Cefamandole interacts with Bio.Me Oral — through 2 ingredients. Tap an ingredient for the detail:
B. Breve W25Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve W25 + Cefamandole interactionBifidobacterium Bifidum W23Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum W23 + Cefamandole interactionCefazolinAncef
How Cefazolin interacts with Bio.Me Oral — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Bifidum W23Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum W23 + Cefazolin interactionB. Breve W25Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve W25 + Cefazolin interactionCefdinirOmnicef
How Cefdinir interacts with Bio.Me Oral — through 2 ingredients. Tap an ingredient for the detail:
B. Breve W25Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve W25 + Cefdinir interactionBifidobacterium Bifidum W23Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum W23 + Cefdinir interactionCefditoren PivoxilSpectracef
How Cefditoren Pivoxil interacts with Bio.Me Oral — through 2 ingredients. Tap an ingredient for the detail:
B. Breve W25Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve W25 + Cefditoren Pivoxil interactionBifidobacterium Bifidum W23Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum W23 + Cefditoren Pivoxil interactionCefepimeMaxipime
How Cefepime interacts with Bio.Me Oral — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Bifidum W23Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum W23 + Cefepime interactionB. Breve W25Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve W25 + Cefepime interactionCefiderocol Sulfate TosylateFetroja
How Cefiderocol Sulfate Tosylate interacts with Bio.Me Oral — through 2 ingredients. Tap an ingredient for the detail:
B. Breve W25Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve W25 + Cefiderocol Sulfate Tosylate interactionBifidobacterium Bifidum W23Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum W23 + Cefiderocol Sulfate Tosylate interactionCefiximeSuprax
How Cefixime interacts with Bio.Me Oral — through 2 ingredients. Tap an ingredient for the detail:
B. Breve W25Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve W25 + Cefixime interactionBifidobacterium Bifidum W23Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum W23 + Cefixime interactionCefmetazoleZefazone
How Cefmetazole interacts with Bio.Me Oral — through 2 ingredients. Tap an ingredient for the detail:
B. Breve W25Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve W25 + Cefmetazole interactionBifidobacterium Bifidum W23Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum W23 + Cefmetazole interactionCefonicidMonocid
How Cefonicid interacts with Bio.Me Oral — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Bifidum W23Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum W23 + Cefonicid interactionB. Breve W25Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve W25 + Cefonicid interactionCefoperazoneCefobid
How Cefoperazone interacts with Bio.Me Oral — through 2 ingredients. Tap an ingredient for the detail:
B. Breve W25Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve W25 + Cefoperazone interactionBifidobacterium Bifidum W23Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum W23 + Cefoperazone interactionCefotaximeClaforan
How Cefotaxime interacts with Bio.Me Oral — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Bifidum W23Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum W23 + Cefotaxime interactionB. Breve W25Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full B. Breve W25 + Cefotaxime interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Bio.Me Oral with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Bifidobacterium bifidum W23
Antibiotic Drugs
Theoretically, taking Bifidobacterium. bifidum with antibiotic drugs might decrease the effectiveness of B. bifidum.
Since B. bifidum preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. bifidum preparations by at least 2 hours.
B. breve W25
Antibiotic Drugs
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B. breve.
Since B. breve preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. breve preparations by at least 2 hours.
Brand information
Manufacturer and brand details for Bio.Me Oral, from the product label.
Invivo
See all Invivo products- Name
- Invivo Healthcare
- State
- UK
- ZipCode
- GL5 2TE
- Web Address
- invivohealthcare.com
Bio.Me Oral by Invivo: Common Questions
Does Bio.Me Oral by Invivo interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this while I'm on an antibiotic?
Is this safe if I have a weak immune system?
What does Bifidobacterium bifidum do?
Can I take this while pregnant?
Does this cause side effects?
Why is this a powder instead of a capsule?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Bio.Me Oral is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Bio.Me Oral’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Bifidobacterium Bifidum
Interacts with 182 drugsBifidobacterium bifidum is a 'friendly' bacteria (probiotic) that naturally lives in the human gut and is taken to support digestion and gut balance. Some evidence suggests probiotics may he...
Read the full Bifidobacterium Bifidum monograph → Herb & supplement monographStreptococcus Thermophilus
Streptococcus thermophilus is a friendly bacterium used as a probiotic, often combined with other strains in yogurt and supplements. It is generally well tolerated in healthy people and may...
Read the full Streptococcus Thermophilus monograph → Herb & supplement monographBifidobacterium Breve
Interacts with 182 drugsBifidobacterium breve is a 'friendly' gut bacterium taken as a probiotic, most often to support digestion and balance the gut microbiome. Some studies suggest possible benefits for certain d...
Read the full Bifidobacterium Breve monograph →Sources & How We Checked
Bio.Me Oral's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 37 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Bifidobacterium Bifidum 7 references
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
- Rerksuppaphol S, Rerksuppaphol L. Randomized controlled trial of probiotics to reduce common cold in schoolchildren. Pediatr Int. 2012;54(5):682-7. PubMed
- Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
- Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
- Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
- Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed
See these in context on the Bifidobacterium Bifidum monograph →
Streptococcus Thermophilus 21 references
- Saxelin M, Chuang NH, Chassy B, et al. Lactobacilli and bacteremia in southern Finland 1989-1992. Clin Infect Dis 1996;22:564-6. PubMed
- Tynkkynen S, Singh KV, Varmanen P. Vancomycin resistance factor of Lactobacillus rhamnosus GG in relation to enterococcal vancomycin resistance (van) genes. Int J Food Microbiol 1998;41:195-204. PubMed
- Klein G, Zill E, Schindler R, et al. Peritonitis associated with vancomycin-resistant Lactobacillus rhamnosus in a continuous ambulatory peritoneal dialysis patient; organism identification, antibiotic therapy, and case report. J Clin Microbiol 1998;36:
- Kalima P, Masterton RG, Roddie PH, et al. Lactobacillus rhamnosus infection in a child following bone marrow transplant. J Infect 1996;32:165-7. PubMed
- Goldin BR. Health Benefits of probiotics. Br J Nutr 1998;80:S203-7. DOI
- Rautio M, Jousimies-Somer H, Kauma H, et al. Liver abscess due to Lactobacillus rhamnosus strain indistinguishable from L. rhamnosus strain GG. Clin Infect Dis 1999;28:1159-60.
- MacGregor G, Smith AJ, Thakker B, Kinsella J. Yoghurt biotherapy: contraindicated in immunosuppressed patients? Postgrad Med J 2002;78:366-7. PubMed
- Land MH, Rouster-Stevens K, Woods CR, et al. Lactobacillus sepsis associated with probiotic therapy. Pediatrics 2005;115:178-81.
- De Groote MA, Frank DN, Dowell E, et al. Lactobacillus rhamnosus GG bacteremia associated with probiotic use in a child with short gut syndrome. Pediatr Infect Dis J 2005;24:278-80. PubMed
- Vahabnezhad E, Mochon AB, Wozniak LJ, Ziring DA. Lactobacillus bacteremia associated with probiotic use in a pediatric patient with ulcerative colitis. J Clin Gastroenterol. 2013;47(5):437-9. PubMed
- Dolatkhah N, Hajifaraji M, Abbasalizadeh F, Aghamohammadzadeh N, Mehrabi Y, Abbasi MM. Is there a value for probiotic supplements in gestational diabetes mellitus? A randomized clinical trial. J Health Popul Nutr. 2015;33:25. PubMed
- Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
- Sendil S, Shrimanker I, Mansoora Q, Goldman J, Nookala VK. Lactobacillus rhamnosus bacteremia in an immunocompromised renal transplant patient. Cureus. 2020;12(2):e6887. PubMed
- Albarillo FS, Shah U, Joyce C, Slade D. Lactobacillus rhamnosus Infection: A single-center 4-year descriptive analysis. J Glob Infect Dis. 2020;12(3):119-123. PubMed
- Pasala S, Singer L, Arshad T, Roach K. Lactobacillus endocarditis in a healthy patient with probiotic use. IDCases. 2020;22:e00915. PubMed
- Agrawal S, Tuchman ES, Bruce MJ, Theodorou ME. Fatal Lactobacillus endocarditis in a patient with transcatheter aortic valve replacement. BMJ Case Rep. 2020;13(11):e236835.
- Antoun M, Hattab Y, Akhrass FA, Hamilton LD. Uncommon pathogen, Lactobacillus, causing infective endocarditis: Case report and review. Case Rep Infect Dis. 2020;2020:8833948. PubMed
- Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
- Franko B, Vaillant M, Recule C, Vautrin E, et al. Lactobacillus paracasei endocarditis in a consumer of probiotics. Med Mal Infect. 2013;43(4):171-3. PubMed
- Campbell RE, Miller A, Afroze A. Native valve endocarditis secondary to Lactobacillus paracasei bacteremia. Consultant. 2020;60(9):27-8. DOI
- Kato K, Funabashi N, Takaoka H, et al. Lactobacillus paracasei endocarditis in a consumer of probiotics with advanced and severe bicuspid aortic valve stenosis complicated with diffuse left ventricular mid-layer fibrosis. Int J Cardiol. 2016;224:157-161. PubMed
See these in context on the Streptococcus Thermophilus monograph →
Bifidobacterium Breve 9 references
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
- Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
- Ohishi A, Takahashi S, Ito Y, et al. Bifidobacterium septicemia associated with postoperative probiotic therapy in a neonate with omphalocele. J Pediatr. 2010;156(4):679-81. PubMed
- Sakurai Y, Watanabe T, Miura Y, et al. Clinical and bacteriologic characteristics of six cases of Bifidobacterium breve bacteremia due to probiotic administration in the neonatal intensive care unit. Pediatr Infect Dis J 2022;41(1):62-65. PubMed
- Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed
- Wakabayashi Y, Nakayama S, Yamamoto A, et al. First case of necrotizing fasciitis and bacteremia caused by Bifidobacteriumbreve. Anaerobe 2022;76:102613.
- Takeda Y, Ota K, Kondo A, et al. A case of necrotizing fasciitis caused by Bifidobacterium breve. IDCases 2022;31:e01667. PubMed
- Suwantarat N, Romagnoli M, Wakefield T, Carroll KC. Ventriculoperitoneal shunt infection caused by Bifidobacterium breve. Anaerobe 2014;28:1-3. PubMed
See these in context on the Bifidobacterium Breve monograph →
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC