Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Bioactive Milk Peptides Ingredients & Drug Interactions

by Life Extension

Capsule Category: Amino Acid/protein
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Bioactive Milk Peptides is a dietary supplement by Life Extension with 1 active ingredient. Its ingredients are commonly taken for high blood pressure, stress and relaxation, sleep support.Based on those ingredients, 172 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Casein decapeptide. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Bioactive Milk Peptides by Life Extension

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This supplement contains one active ingredient: casein decapeptide, a peptide derived from milk protein. Casein peptides are small protein fragments that your body may absorb more readily than whole milk proteins.

The capsule also contains several inactive ingredients — microcrystalline cellulose, cellulose, silica, and stearate — which help hold the capsule together and keep the powder flowing smoothly during manufacturing.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Casein Peptides's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: stress relief and sleep support.
  • We looked for evidence on: Stress, Anxiety, Insomnia.
  • The closest evidence on file: Casein Peptides is rated "Insufficient Reliable Evidence To Rate" for Anxiety (Natural Medicines).
  • Also on file: Casein Peptides is rated "Insufficient Reliable Evidence To Rate" for Insomnia, Stress.

The evidence supports casein peptides for two main uses. They're rated Likely Effective for atopic dermatitis (eczema) and for food allergies.

If you're dealing with either of those, the data we hold suggests there's real benefit to expect from this ingredient — though individual results vary, and talking with your doctor about how it fits into your overall care plan is always a good idea.

The evidence, ingredient by ingredient Casein Peptides

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Casein decapeptide is generally well tolerated in healthy adults. The main caution is straightforward: if you have a milk allergy, you should avoid this product.

Beyond that, concentrated supplements of casein peptides haven't been studied extensively at the doses used in supplements, so safety data is limited. The manufacturer recommends avoiding concentrated supplements unless your doctor has advised you to take one.

If you're considering this long-term, it's worth a conversation with your pharmacist or doctor about whether it's right for you.

Side effects, ingredient by ingredient Casein Peptides

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Casein Peptides.
  • The most serious interaction on file is rated Moderate.
  • For scale: 172 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take antihypertensive drugs (blood pressure medications) of any kind, check your exact medications with the tool on this page before you start. Casein peptides can lower blood pressure, so combining them with your medication could drop your pressure too far.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and some safety-information gaps remain.

This supplement is worth considering if you have eczema or food allergies and are looking for a milk-derived option — the evidence backs its use for those conditions. If you're on blood pressure medication, you'll need to check with your pharmacist first.

And if you have a milk allergy, this isn't for you. Talk to your pharmacist before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 24, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Bioactive Milk Peptides, straight from the product label.

Brand Life Extension
Barcode (UPC) 737870151234
Net contents 30 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Apr 24, 2025
DSLD ID 328851
Product type Amino Acid/protein
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Bioactive Milk Peptides by Life Extension, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Vegetarian Capsule(s)
Maximum serving Sizes:
1 Vegetarian Capsule(s)
Servings per container
30
UPC/BARCODE
737870151234
IngredientAmount% DV
Casein decapeptide150 mg--

Other ingredients: Microcrystalline Cellulose, Cellulose, Silica, Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Scan for product info

Precautions

Read the entire label and follow the directions carefully prior to use.

Warnings: Keep out of reach of children.

Do not exceed recommended dose. Do not purchase if outer seal is broken or damaged.

When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

Contains milk (casein decapeptide).

To report a serious adverse event or obtain product information, contact 1-866-280-2852.

Suggested/Recommended/Usage/Directions

Directions: Take one (1) capsule daily, or as recommended by a healthcare practitioner. May be taken during daytime for stress or before bed to help with sleep.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formulation

Gluten free Non GMO LE Certified

Mood and sleep support

Seals/Symbols

Non GMO LE Certified

FDA Statement of Identity

Dietary Supplement

Storage

Store tightly closed in a cool, dry place.

Brand IP Statement(s)

Lactium is used under license.

See for yourself

Bioactive Milk Peptides by Life Extension label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Bioactive Milk Peptides by Life Extension

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Vegetarian Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Casein decapeptide

Interacts with
172 drugs
150 mg per serving Form: bioactive Milk Peptides

Casein peptides are small protein fragments made from milk casein, often studied for mild blood pressure support and relaxation. The evidence is limit...

Casein decapeptide monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Cellulose, Silica, Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Bioactive Milk Peptides by Life Extension Drug Interactions

Want to check YOUR meds against Bioactive Milk Peptides?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
172Drugs
172 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Bioactive Milk Peptides with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Casein decapeptide1 drug type · 172 drugs

Antihypertensive Drugs

Theoretically, combining these casein peptides with antihypertensive drugs might increase the risk of hypotension.
Clinical research shows that some casein peptides, including the lactotripeptides isoleucine-proline-proline (IPP) and valine-proline-proline (VPP), can modestly reduce blood pressure in patients with hypertension.

Likelihood Probable Evidence B
The maker

Brand information

Manufacturer and brand details for Bioactive Milk Peptides, from the product label.

Life Extension

See all Life Extension products
Name
Quality Supplements and Vitamins, Inc.
City
Ft. Lauderdale
State
FL
ZipCode
33309
Phone Number
1-866-280-2852
Web Address
LifeExtension.com
Pharmacist Counseling Corner

Bioactive Milk Peptides by Life Extension: Common Questions

Does Bioactive Milk Peptides by Life Extension interact with any medications?
Yes. Based on its ingredients, Bioactive Milk Peptides has a known interaction with 172 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Bioactive Milk Peptides contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help my eczema?
Yes — casein peptides are rated Likely Effective for atopic dermatitis (eczema). The evidence supports their use for that condition. Results vary from person to person, so it may take a few weeks to notice a difference.
I have a milk allergy. Can I take this?
No, you should avoid this product. Even though casein peptides are processed fragments of milk protein, people with milk allergies should steer clear of them.
Is this safe to take long-term?
Casein peptides are generally well tolerated in healthy adults, but concentrated supplement doses haven't been studied extensively over time. The safety data we hold is limited, so if you're thinking about taking this regularly, talk it over with your pharmacist or doctor first.
What exactly is casein decapeptide?
It's a small protein fragment made from milk protein. 'Decapeptide' means it's made of ten amino acids linked together — small enough that your body can absorb it more easily than whole milk protein.
Will this help with food allergies?
Casein peptides are rated Likely Effective for food allergies based on the evidence we hold. That said, food allergies are serious, so talk with your doctor about how this fits into your overall allergy management plan.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Bioactive Milk Peptides is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Bioactive Milk Peptides label
Sources

Sources & How We Checked

Bioactive Milk Peptides's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Casein Peptides 4 references
  1. Cicero AFG, Aubin F, Azais-Braesco V, Borghi C. Do the lactotripeptides isoleucine-proline-proline and valine-proline-proline reduce systolic blood pressure in European subjects? A meta-analysis of randomized controlled trials. Am J Hypertens. 2013;26(3): PubMed
  2. Fekete AA, Givens DA, Lovegrove JA. Casein-derived lactotripeptides reduce systolic and diastolic blood pressure in a meta-analysis of randomised clinical trials. Nutrients. 2015;7(1):659-81. PubMed
  3. Qin LQ, Xu JY, Dong JY, Zhao Y, van Bladeren P, Zhang W. Lactotripeptides intake and blood pressure management: a meta-analysis of randomised controlled clinical trials. Nutr Metab Cardiovasc Dis. 2013;23(5):395-402. PubMed
  4. Turpeinen AM, Järvenpää S, Kautiainen H, Korpela R, Vapaatalo H. Antihypertensive effects of bioactive tripeptides-a random effects meta-analysis. Ann Med. 2013;45(1):51-6. PubMed

See these in context on the Casein Peptides monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring