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Dietary supplement

Biothin Probiotic 10 Billion CFU Ingredients & Drug Interactions

by Dr. Mercola

Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Biothin Probiotic 10 Billion CFU is a dietary supplement by Dr. Mercola with 1 active ingredient. Its ingredients are commonly taken for digestive health, weight and belly fat management, vaginal and urinary health.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lactobacillus gasseri BNR17. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Biothin Probiotic 10 Billion CFU by Dr. Mercola

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Biothin Probiotic contains one active ingredient: Lactobacillus gasseri BNR17, a beneficial probiotic strain containing live microorganisms. The product also includes several inactive ingredients — microcrystalline cellulose, hydroxypropyl methylcellulose, gellan gum, fructooligosaccharides, ascorbyl palmitate, and silicon dioxide — which serve as capsule material, binders, and preservative support.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Lactobacillus Gasseri's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Supports metabolic health.
  • We looked for evidence on: Obesity, Weight management, Metabolic syndrome, Body composition.
  • The closest evidence on file: Lactobacillus Gasseri is rated "Insufficient Reliable Evidence To Rate" for Obesity (Natural Medicines).

The evidence for Lactobacillus gasseri is not established in our data. We hold insufficient reliable evidence to rate it for allergic rhinitis (hay fever), aspirin-associated stomach damage, asthma, bacterial vaginosis, common cold, and diarrhea.

That doesn't mean it doesn't work for these conditions — it means the research we have isn't robust enough to call it effective. Talk with your doctor or pharmacist about what the current science actually supports for what you're hoping to address.

The evidence, ingredient by ingredient Lactobacillus Gasseri

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lactobacillus gasseri is generally well tolerated in healthy adults, but the safety evidence is limited and incomplete. The product comes with a caution: not enough reliable safety data exists, so use it only under a doctor's guidance.

Because these are live, active microorganisms, there is a theoretical concern that in some patients — especially those with weakened immune systems or other risk factors — the bacteria could spread beyond the gut and cause infection. Cases of bacteremia, sepsis, endocarditis, and other serious infections involving lactobacilli have been reported in the medical literature, though these are thought to occur mainly when bacteria translocate from the mouth or other natural sites.

Pregnancy and lactation safety data are not on file for this ingredient.

Side effects, ingredient by ingredient Lactobacillus Gasseri

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Lactobacillus Gasseri.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your pharmacist or doctor before taking this product if you use antibiotics. Timing matters: antibiotics can kill the live organisms in the probiotic and reduce its effectiveness.

Altogether, these interactions span 182 individual medications. Use the medication checker below to look up your exact drugs.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This probiotic is a single-strain formula that's generally tolerated well in healthy people, but the evidence for what it actually does is limited. If you take antibiotics, space out your doses.

Most importantly, talk with your doctor or pharmacist before starting — especially if you have a weakened immune system, recent surgery, or other risk factors — so they can make sure it's right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Biothin Probiotic 10 Billion CFU, straight from the product label.

Brand Dr. Mercola
Barcode (UPC) 810487036481
Net contents 30 Capsule(s)
Market status On market
Date entered into DSLD Feb 23, 2025
DSLD ID 327105
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Biothin Probiotic 10 Billion CFU by Dr. Mercola, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
30
UPC/BARCODE
810487036481
IngredientAmount% DV
Lactobacillus gasseri BNR17250 mg--

Other ingredients: Microcrystalline Cellulose, Hydroxypropyl Methylcellulose, Gellan Gum, Fructooligosaccharides, Ascorbyl Palmitate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: Adults, as a dietary supplement, take one (1) capsule daily with a meal.

Formulation

Supports metabolic health

Precautions

Keep out of reach of children.

Do not use if safety seal is broken.

If you are nursing, pregnant, taking medication or have a medical condition, consult your physician before taking this product.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formula

Lactobacillus gasseri

FDA Statement of Identity

Dietary Supplement

General Statements

Providing quality products since 2001.

Brand IP Statement(s)

BNR17 is a trademark of AceBiome/Bioneer, is manufactured by Chr. Hansen A/S and used under license.

See for yourself

Biothin Probiotic 10 Billion CFU by Dr. Mercola label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Biothin Probiotic 10 Billion CFU by Dr. Mercola

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Lactobacillus gasseri BNR17

Interacts with
182 drugs
250 mg per serving

Lactobacillus gasseri is a 'friendly' probiotic bacterium found naturally in the human gut, mouth, and vaginal tract, and in some fermented foods. Ear...

Lactobacillus gasseri BNR17 monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Hydroxypropyl Methylcellulose, Gellan Gum, Fructooligosaccharides, Ascorbyl Palmitate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Biothin Probiotic 10 Billion CFU by Dr. Mercola Drug Interactions

Want to check YOUR meds against Biothin Probiotic 10 Billion CFU?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Biothin Probiotic 10 Billion CFU with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Lactobacillus gasseri BNR171 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus gasseri with antibiotic drugs might decrease the effectiveness of L. gasseri.
Lactobacillus gasseri preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. gasseri preparations by at least two hours.

Likelihood Probable Evidence D
The maker

Brand information

Manufacturer and brand details for Biothin Probiotic 10 Billion CFU, from the product label.

Dr. Mercola

See all Dr. Mercola products
Name
NHP
Street Address
125 SW 3rd Place
City
Cape Coral
State
FL
ZipCode
33991
Phone Number
(877) 985-2696
Pharmacist Counseling Corner

Biothin Probiotic 10 Billion CFU by Dr. Mercola: Common Questions

Does Biothin Probiotic 10 Billion CFU by Dr. Mercola interact with any medications?
Yes. Based on its ingredients, Biothin Probiotic 10 Billion CFU has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Biothin Probiotic 10 Billion CFU contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What exactly is Lactobacillus gasseri BNR17?
It's a beneficial probiotic strain — a live microorganism — included in this product. Probiotics are intended to support gut health, though the evidence for what this particular strain actually does is not strong enough in our data to call it proven.
Can I take this with my antibiotics?
Not at the same time. Antibiotics can kill the live bacteria in the probiotic, making it less effective. Talk with your pharmacist about spacing — usually waiting until after your antibiotic course to start the probiotic works best.
Is this safe during pregnancy or while breastfeeding?
We don't have safety data on file for this ingredient during pregnancy or lactation. Talk with your doctor or midwife to see if it's right for you.
What side effects should I watch for?
Most people tolerate it well. The main theoretical concern is that in some patients — especially those with weakened immunity — the live bacteria could spread and cause infection, though this is rare. Tell your doctor right away if you develop signs of infection like fever, chills, or unusual symptoms after starting.
Does this actually work for diarrhea or colds?
We don't have enough reliable evidence to say it works for diarrhea, common cold, or the other conditions listed. The research just isn't there yet. Ask your pharmacist what the current science actually shows.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Biothin Probiotic 10 Billion CFU is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Biothin Probiotic 10 Billion CFU label
Sources

Sources & How We Checked

Biothin Probiotic 10 Billion CFU's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lactobacillus Gasseri 12 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Ramachandran L, Dontaraju VS, Patel K. Lactobacillus-associated spontaneous bacterial peritonitis in a liver cirrhosis patient on probiotics. Cureus. 2020;12(12):e11896. PubMed
  3. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  4. Ranchal P, Gupta R, Goldberg R, A Lobo S, Pascual A, El Khoury MY. Penicillin-sensitive Lactobacillus jensenii bacteremia. Am J Ther 2021;28(2):e250-e252. PubMed
  5. Grazioli-Gauthier L, Rigamonti E, Leo LA, Martinetti Lucchini G, Lo Priore E, Bernasconi E. Lactobacillus jensenii mitral valve endocarditis: Case report, literature review and new perspectives. IDCases 2022;27:e01401. PubMed
  6. Toprak NU, Bozan T, Yilmaz S, Buyukbayrak EE, Tigen ET. Polymicrobial bacteremia due to Lactobacillus jensenii and Veillonella montpellierensis in a pregnant patient; case report and review of literature. Anaerobe 2022;75:102576. PubMed
  7. Chazan B, Raz R, Shental Y, Sprecher H, Colodner R. Bacteremia and pyelonephritis caused by Lactobacillus jensenii in a patient with urolithiasis. Isr Med Assoc J 2008;10(2):164-5.
  8. Ramos-Coria D, Canto-Losa J, Carrillo-Vázquez D, Carbajal-Morelos L, Estrada-León R, Corona-Rodarte E. Lactobacillus gasseri liver abscess and bacteremia: a case report. BMC Infect Dis 2021;21(1):518. PubMed
  9. Elikowski W, Malek-Elikowska M, Lisiecka M, Bodora A, Wisniewska K, Oko-Sarnowska Z. Lactobacillus gasseri endocarditis on the aortic valve bioprosthesis - a case report. Pol Merkur Lekarski 2017;43(257):220-223.
  10. Esquibel A, Dababneh AS, Palraj BR. Lactobacillus gasseri causing bilateral empyema. Case Rep Infect Dis 2017;2017:4895619.
  11. Tleyjeh IM, Routh J, Qutub MO, Lischer G, Liang KV, Baddour LM. Lactobacillus gasseri causing Fournier's gangrene. Scand J Infect Dis 2004;36(6-7):501-3. PubMed
  12. Dickgiesser U, Weiss N, Fritsche D. Lactobacillus gasseri as the cause of septic urinary infection. Infection 1984;12(1):14-6. PubMed

See these in context on the Lactobacillus Gasseri monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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