Bitter Melon 1200 mg Ingredients & Drug Interactions
by Carlyle
What is this page for?
First and foremost: checking Bitter Melon 1200 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Bitter Melon 1200 mg is a dietary supplement by Carlyle with 1 active ingredient. Its ingredients are commonly taken for blood sugar support, diabetes, digestive complaints.Based on those ingredients, 282 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bitter Melon. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Bitter Melon 1200 mg by Carlyle
Ask about any prescription or over-the-counter medication and we check it for interactions with Bitter Melon 1200 mg by Carlyle — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Bitter Melon 1200 mg by Carlyle
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: bitter melon fruit extract at 1200 mg per capsule. Bitter melon is a tropical plant traditionally used in herbal medicine; the extract concentrates its compounds into a convenient capsule form.
The remaining ingredients—rice powder, gelatin, magnesium stearate, and silica—are inactive excipients that help form and stabilize the capsule.
Does it work?
Not established
The evidence we hold does not establish that bitter melon is effective for any condition. The available data rates its use for amenorrhea, athletic performance, liver disease, constipation, diabetes, and indigestion all as having insufficient reliable evidence.
This doesn't mean bitter melon doesn't work—only that the research backing its use for these purposes isn't yet strong enough to draw firm conclusions.
How safe is it?
Well-documented data
Bitter melon is generally well tolerated when taken by mouth, but it does come with cautions. The most common side effects are gastrointestinal: heartburn, nausea, vomiting, diarrhea, constipation, flatulence, and abdominal discomfort occurred in about 3% to 16% of people in studies.
You might also experience dizziness, fatigue, or headache. Rarely, very low blood sugar (hypoglycemia) and seizures (mainly in children) have been reported.
One case report documented a person who developed kidney inflammation after taking bitter melon extract at increasing doses (600 mg daily, then 1200 mg daily) over seven months; their kidney function recovered after stopping the supplement. Because of these safety concerns, traditional medicine advises against bitter melon in pregnancy—the seeds and high doses may cause harmful effects.
There isn't enough reliable data on safety during breastfeeding, so it's best avoided then too.
Meds to double-check
Moderate interaction found
Check with your pharmacist if you take diabetes or blood sugar medications (risk of low blood sugar), any P-glycoprotein substrate drugs (which may accumulate to higher levels), or pazopanib for cancer. These carry Moderate interaction severity and need dose or timing adjustments.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
Bitter melon may appeal to people interested in traditional herbal remedies, but the evidence for its effectiveness isn't yet established in our data. More importantly, if you take diabetes medications, P-glycoprotein substrate drugs (certain cancer treatments), or pazopanib, this product poses real interaction risks.
Talk with your pharmacist before starting—especially if you're pregnant, breastfeeding, or managing blood sugar.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 24, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Bitter Melon 1200 mg, straight from the product label.
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Bitter Melon 1200 mg by Carlyle, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Bitter Melon Fruit Extract | 120 mg | -- |
| Bitter Melon | 1200 mg | -- |
Other ingredients: Rice, Powder, Gelatin, Magnesium Stearate, Silica
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Bitter Melon 1200mg Equivalent from 120mg of 10:1 extract. Traditional herb
Formulation
Non-GMO Gluten free
100% Highest quality Ethically sourced ingredients
No Gluten Wheat Yeast Milk Lactose Soy Artificial color Artificial flavor Artificial sweetener Preservatives Non GMO
FDA Statement of Identity
Herbal supplement
Suggested/Recommended/Usage/Directions
Directions: For adults, take one (1) quick release capsule daily, preferably with a meal.
Seals/Symbols
Packaged & lab tested in the USA Good Manufacturing Practice GMP
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Bitter Melon 1200 mg by Carlyle label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Bitter Melon 1200 mg by Carlyle
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Quick Release Capsule(s) Dosage formCapsule Servings per container180 Amounts shown are per serving.
Bitter Melon
Interacts with282 drugs
Bitter melon is a tropical fruit eaten as food and used in traditional medicine, most often for blood sugar control. While some small studies hint it...
Bitter Melon monograph & interactionsOther (inactive) ingredients: Rice, Powder, Gelatin, Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.
Bitter Melon 1200 mg by Carlyle Drug Interactions
HelloPharmacist Interaction Report
Carlyle's Bitter Melon 1200 mg contains a single active ingredient—bitter melon fruit extract—that does interact with medications.
The most serious concern is with P-glycoprotein substrates (Moderate severity), a group of drugs whose levels in your body bitter melon may increase. In laboratory studies, a compound in bitter melon raised levels of daunomycin, a P-glycoprotein substrate used in cancer treatment, suggesting it could affect how your body handles similar medications.
Read the full breakdown — every affected drug type, severity by severity
Bitter melon also interacts with blood sugar medications (Moderate severity). Because bitter melon naturally lowers blood glucose, taking it alongside diabetes drugs could tip your blood sugar too low (hypoglycemia)—dizziness, shakiness, or worse.
You'd need to monitor your levels closely and likely adjust your medication dose.
One more Moderate interaction: pazopanib (Votrient), a kidney cancer drug. A case report describes a patient on pazopanib for years who developed acute pancreatitis four days after starting bitter melon juice.
While rare, this interaction warrants caution.
Altogether, these interactions span 275 individual medications. Use the search tool on this page to check your exact prescriptions before starting.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Bitter Melon 1200 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Bitter Melon 1200 mg interact with 282 drugs. Click any drug to see the details.
1 of the 1 ingredient in Bitter Melon 1200 mg interact with drugs. Each result below shows which ingredient is responsible. Bitter Melon
AcalabrutinibCalquence
How Acalabrutinib interacts with Bitter Melon 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Bitter MelonP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon + Acalabrutinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Bitter Melon 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Bitter MelonAntidiabetes Drugs Moderate
Interaction Summary
Taking bitter melon with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Bitter Melon + Acarbose interactionAcetohexamideDymelor
How Acetohexamide interacts with Bitter Melon 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Bitter MelonAntidiabetes Drugs Moderate
Interaction Summary
Taking bitter melon with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Bitter Melon + Acetohexamide interactionAfatinib DimaleateGilotrif
How Afatinib Dimaleate interacts with Bitter Melon 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Bitter MelonP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon + Afatinib Dimaleate interactionAlbiglutideTanzeum
How Albiglutide interacts with Bitter Melon 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Bitter MelonAntidiabetes Drugs Moderate
Interaction Summary
Taking bitter melon with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Bitter Melon + Albiglutide interactionAlogliptinNesina
How Alogliptin interacts with Bitter Melon 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Bitter MelonAntidiabetes Drugs Moderate
Interaction Summary
Taking bitter melon with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Bitter Melon + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Bitter Melon 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Bitter MelonAntidiabetes Drugs Moderate
Interaction Summary
Taking bitter melon with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Bitter Melon + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Bitter Melon 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Bitter MelonAntidiabetes Drugs Moderate
Interaction Summary
Taking bitter melon with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Bitter Melon + Alogliptin, Pioglitazone interactionAlvimopanEntereg
How Alvimopan interacts with Bitter Melon 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Bitter MelonP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon + Alvimopan interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with Bitter Melon 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Bitter MelonP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon + Ambrisentan interactionAmphotericin, TetracyclineMysteclin-F
How Amphotericin, Tetracycline interacts with Bitter Melon 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Bitter MelonP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon + Amphotericin, Tetracycline interactionAmprenavirAgenerase
How Amprenavir interacts with Bitter Melon 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Bitter MelonP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon + Amprenavir interactionAntidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) InhibitorGlyxambi
How Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interacts with Bitter Melon 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Bitter MelonP-glycoprotein Substrates, Antidiabetes Drugs Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interactionApixabanEliquis
How Apixaban interacts with Bitter Melon 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Bitter MelonP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon + Apixaban interactionApomorphineAPO-go, APO-go Pen, APO-go PFS, Apokyn, Uprima
How Apomorphine interacts with Bitter Melon 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Bitter MelonP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon + Apomorphine interactionApomorphine HydrochlorideKynmobi
How Apomorphine Hydrochloride interacts with Bitter Melon 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Bitter MelonP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon + Apomorphine Hydrochloride interactionArmodafinilNuvigil
How Armodafinil interacts with Bitter Melon 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Bitter MelonP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon + Armodafinil interactionAtogepantQulipta
How Atogepant interacts with Bitter Melon 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Bitter MelonP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon + Atogepant interactionAtropine, Morphine SulfateAtropine, Morphine Sulfate
How Atropine, Morphine Sulfate interacts with Bitter Melon 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Bitter MelonP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon + Atropine, Morphine Sulfate interactionAvatrombopag MaleateDoptelet
How Avatrombopag Maleate interacts with Bitter Melon 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Bitter MelonP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon + Avatrombopag Maleate interactionBazedoxifene Acetate, Conjugated EstrogensDuavee
How Bazedoxifene Acetate, Conjugated Estrogens interacts with Bitter Melon 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Bitter MelonP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon + Bazedoxifene Acetate, Conjugated Estrogens interactionBeclometasone DipropionateBecotide
How Beclometasone Dipropionate interacts with Bitter Melon 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Bitter MelonP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon + Beclometasone Dipropionate interactionBeclomethasoneBeclovent, Vanceril
How Beclomethasone interacts with Bitter Melon 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Bitter MelonP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon + Beclomethasone interactionBeclomethasone DipropionateQNASL, Qvar
How Beclomethasone Dipropionate interacts with Bitter Melon 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Bitter MelonP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon + Beclomethasone Dipropionate interactionBelinostatBeleodaq
How Belinostat interacts with Bitter Melon 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Bitter MelonP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon + Belinostat interactionBerotralstat HydrochlorideOrladeyo
How Berotralstat Hydrochloride interacts with Bitter Melon 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Bitter MelonP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon + Berotralstat Hydrochloride interactionBetamethasoneCelestone, Diprolene AF, Diprosone
How Betamethasone interacts with Bitter Melon 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Bitter MelonP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon + Betamethasone interactionBetamethasone DipropionateSernivo
How Betamethasone Dipropionate interacts with Bitter Melon 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Bitter MelonP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon + Betamethasone Dipropionate interactionBetamethasone Dipropionate, CalcipotrieneEnstilar, Wynzora
How Betamethasone Dipropionate, Calcipotriene interacts with Bitter Melon 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Bitter MelonP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon + Betamethasone Dipropionate, Calcipotriene interactionBetamethasone ValerateLuxiq
How Betamethasone Valerate interacts with Bitter Melon 1200 mg — through 1 ingredient. Tap an ingredient for the detail:
Bitter MelonP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon + Betamethasone Valerate interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Bitter Melon 1200 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Bitter Melon
Antidiabetes Drugs
Taking bitter melon with antidiabetes drugs might increase the risk of hypoglycemia.
Bitter melon can lower blood glucose levels and might have additive effects when used with antidiabetes drugs. This might increase the risk of hypoglycemia in some patients. Monitor blood glucose levels closely.
P-Glycoprotein Substrates
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Bitter melon might inhibit the p-glycoprotein (P-gp) intestinal pump and increase intracellular levels of P-gp substrates. In vitro research in intestinal cells shows that 1-monopalmitin, a constituent of bitter melon, increases levels of daunomycin, a P-gp substrate. Additionally, drinking bitter melon juice has been associated with a case of acute pancreatitis in a patient who had been taking pazopanib, a P-gp substrate, for 8 years. Researchers theorize that inhibition of P-gp led to increased levels of pazopanib, resulting in pazopanib-induced pancreatitis.
Pazopanib (Votrient)
Theoretically, bitter melon might increase levels of pazopanib, potentially increasing the risk of adverse effects.
In one case, a 65-year-old patient taking pazopanib for 8 years for renal cell carcinoma experienced signs and symptoms consistent with acute pancreatitis 4 days after drinking bitter melon juice at a dose of 100-150 mL daily. The patient's symptoms, amylase levels, and lipase levels improved upon discontinuation of bitter melon and pazopanib. Pazopanib treatment was re-initiated with no further evidence of pancreatitis. Researchers theorize that inhibition of P-glycoprotein by bitter melon led to increased levels of pazopanib, a P-glycoprotein substrate, resulting in pazopanib-induced pancreatitis.
Brand information
Manufacturer and brand details for Bitter Melon 1200 mg, from the product label.
Bitter Melon 1200 mg by Carlyle: Common Questions
Does Bitter Melon 1200 mg by Carlyle interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take bitter melon if I'm pregnant or breastfeeding?
What are the most common side effects?
Will bitter melon help my blood sugar or diabetes?
What is bitter melon and why is it in supplements?
Is there anything else I should watch for?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Bitter Melon 1200 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Bitter Melon 1200 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Bitter Melon 1200 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 18 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Bitter Melon 18 references
- Leatherdale B, Panesar RK, Singh G, et al. Improvement in glucose tolerance due to Momordica charantia. Br Med J (Clin Res Ed) 1981;282:1823-4.
- Welihinda J, et al. Effect of Momordica charantia on the glucose tolerance in maturity onset diabetes. J Ethnopharmacol 1986;17:277-82. PubMed
- Srivastava Y, Venkatakrishna-Bhatt H, Verma Y, et al. Antidiabetic and adaptogenic properties of Momordica charantia extract: An experimental and clinical evaluation. Phytother Res 1993;7:285-9.
- Baldwa VS, Bhandari CM, Pangaria A, Goyal RK. Clinical trial in patients with diabetes mellitus of an insulin-like compound obtained from plant sources. Ups J Med Sci 1977;82:39-41. PubMed
- Aslam M, Stockley IH. Interaction between curry ingredient (karela) and drug (chlorpropamide). Lancet 1979:1:607. PubMed
- Ahmad N, Hassan MR, Halder H, Bennoor KS. Effect of Momordica charantia (Karolla) extracts on fasting and postprandial serum glucose levels in NIDDM patients (abstract). Bangladesh Med Res Counc Bull 1999;25:11-3.
- Basch E, Gabardi S, Ulbricht C. Bitter melon (Momordica charantia): a review of efficacy and safety. Am J Health Syst Pharm 2003;60:356-9. PubMed
- Yin RV, Lee NC, Hirpara H, Phung OJ. T. The effect of bitter melon (Mormordica charantia) in patients with diabetes mellitus: s systematic review and meta-analysis. Nutr Diabetes. 2014;4:e145.
- Rahman IU, Khan RU, Rahman KU, Bashir M. Lower hypoglycemic but higher antiatherogenic effects of bitter melon than glibenclamide in type 2 diabetic patients. Nutr J. 2015;14:13. PubMed
- Alam MA, Uddin R, Subhan N, Rahman MM, Jain P, Reza HM. Beneficial role of bitter melon supplementation in obesity and related complications in metabolic syndrome. J Lipids. 2015;2015:496169. PubMed
- Konishi T, Satsu H, Hatsugai Y, et al. Inhibitory effect of a bitter melon extract on the P-glycoprotein activity in intestinal Caco-2 cells. Br J Pharmacol. 2004;143(3):379-87. PubMed
- Peter EL, Kasali FM, Deyno S, et al. Momordica charantia L. lowers elevated glycaemia in type 2 diabetes mellitus patients: Systematic review and meta-analysis. J Ethnopharmacol. 2019;231:311-24. doi: 10.1016/j.jep.2018.10.033. PubMed
- Cortez-Navarrete M, Martínez-Abundis E, Pérez-Rubio KG, González-Ortiz M, Méndez-Del Villar M. Momordica charantia administration improves insulin secretion in type 2 diabetes mellitus. J Med Food. 2018;21(7):672-7. doi: 10.108
- Kim SK, Jung J, Jung JH, et al. Hypoglycemic efficacy and safety of Momordica charantia (bitter melon) in patients with type 2 diabetes mellitus. Complement Ther Med. 2020 Aug;52:102524. doi: 10.1016/j.ctim.2020.102524. PubMed
- Unsal O, Sütcüoglu O, Yazici O. Dangerous interaction of bitter melon (Momordica charantia) with pazopanib: a case of acute pancreatitis. J Oncol Pharm Pract 2022;28(2):486-8.
- Bae W, Kim S, Choi J, et al. Acute interstitial nephritis associated with ingesting a Momordica charantia extract: a case report. Medicine (Baltimore) 2021;100(27):e26606. PubMed
- Chattopadhyay K, Wang H, Kaur J, et al. Effectiveness and Safety of Ayurvedic Medicines in Type 2 Diabetes Mellitus Management: A Systematic Review and Meta-Analysis. Front Pharmacol. 2022;13:821810. Published 2022 Jun 8. PubMed
- Kim B, Lee HS, Kim HJ, et al. Momordica charantia (bitter melon) efficacy and safety on glucose metabolism in Korean prediabetes participants: a 12-week, randomized clinical study. Food Sci Biotechnol 2022;32(5):697-704. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC