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Dietary supplement

BosPro 500 mg Ingredients & Drug Interactions

by EuroMedica

BosPro 500 mg label
See full label image
Softgel Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking BosPro 500 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

BosPro 500 mg is a dietary supplement by EuroMedica with 1 active ingredient. Its ingredients are commonly taken for osteoarthritis joint pain, rheumatoid arthritis, inflammation.Based on those ingredients, 952 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are BosPure. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against BosPro 500 mg by EuroMedica

Ask about any prescription or over-the-counter medication and we check it for interactions with BosPro 500 mg by EuroMedica — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of BosPro 500 mg by EuroMedica

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 23, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

BosPro 500 mg contains one active ingredient: boswellia serrata, a resin extract from the frankincense tree, supplied here as BosPure. The softgel capsule also contains inactive ingredients (sunflower oil, gelatin, glycerin, sunflower lecithin, purified water, yellow beeswax, silica, caramel color, and titanium dioxide) that help form and deliver the supplement.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Lung, bronchial, and intestinal support.
  • We looked for evidence on: Asthma, Crohn disease, Irritable bowel syndrome (IBS), Osteoarthritis, Rheumatoid arthritis (RA), Ulcerative colitis — and 3 related terms.
  • The strongest evidence on file: Boswellia Serrata is rated "Possibly Effective" for Osteoarthritis (Natural Medicines).
  • Also on file: Boswellia Serrata is rated "Insufficient Reliable Evidence To Rate" for Asthma, Crohn disease, Ulcerative colitis, Irritable bowel syndrome (IBS), and more.

Boswellia serrata is possibly effective for osteoarthritis — the evidence supports that it may help with joint pain and stiffness in that condition. For allergic rhinitis (hay fever), Alzheimer disease, asthma, and cluster headache, the evidence we hold is insufficient to rate whether it works; more research is needed to know.

The evidence, ingredient by ingredient Boswellia Serrata

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Orally, boswellia serrata is generally well tolerated in the short term, though quality and dose vary widely between products. The most common side effects are abdominal pain, diarrhea, headache, heartburn, itching, and nausea.

Headache was reported by nearly 11% of participants in one clinical trial. A rare serious concern is bezoar formation (a hard mass in the stomach) from large amounts of the gum resin.

The safety data advises against use during pregnancy because there isn't enough safety information. Breastfeeding is best avoided for the same reason — safety is unknown.

If you're pregnant, nursing, or planning either, talk with your doctor or pharmacist before taking this product.

Side effects, ingredient by ingredient Boswellia Serrata

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Boswellia Serrata.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs.
  • For scale: 953 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking BosPro, check with your pharmacist or doctor if you take medications broken down by CYP2D6 (Moderate severity), CYP2C19, CYP1A2, CYP2C9, or CYP3A4 liver enzymes — boswellia may raise their blood levels. If you also take immunosuppressants, you'll want to confirm it's okay to combine them.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

BosPro may help with osteoarthritis symptoms, but it interacts with a large number of medications by affecting how your liver breaks them down. If you take any prescription drugs — especially antidepressants, blood thinners, heart or blood pressure medications, or immunosuppressants — check with your own pharmacist or doctor before starting it.

Pregnancy and breastfeeding are not recommended without talking it over first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 24, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about BosPro 500 mg, straight from the product label.

Brand EuroMedica
Barcode (UPC) 367703843069
Net contents 60 Softgel(s)
Market status On market
Date entered into DSLD Jan 24, 2024
DSLD ID 304139
Product type Botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for BosPro 500 mg by EuroMedica, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
60
UPC/BARCODE
367703843069
IngredientAmount% DV
BosPure500 mg--

Other ingredients: Sunflower Oil, Gelatin, Glycerin, Sunflower Lecithin, Water, Purified, Yellow Beeswax, Silica, Caramel color, Titanium Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Boswellia, also known as frankincense, has been a vital component of Ayurvedic medicine for thousands of years. Modern research has confirmed the effectiveness of boswellia for healthy lung and bronchial function, as well as intensive intestinal support.

Features clinically studied, uniquely standardized BosPure Boswellia Contains boswellia with high levels of naturally occurring AKBA - no spiking or artificial manipulation to increase this beneficial compound.

Boswellia for advanced lung, bronchial, and intestinal support Cliinically studied BosPure boswellia

Formulation

Extra strength for advanced support; up to 10 times more powerful than unstandardized boswellia Purified to reduce undesirable beta-boswellic acid (BBA) content

No sugar, salt, soy, yeast, wheat, gluten, corn, dairy products, artificial flavoring, or artificial preservatives. Non-GMO

Suggested/Recommended/Usage/Directions

Recommendations: 1 softgel daily, or as recommended by your healthcare practitioner.

Precautions

If pregnant or nursing, consult a healthcare practitioner before use.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

BosPure is a registered trademark of Dolcas-Biotech

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

BosPro 500 mg by EuroMedica label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

BosPro 500 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in BosPro 500 mg by EuroMedica

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container60 Amounts shown are per serving.

BosPure

Interacts with
952 drugs
500 mg per serving Form: Boswellia serrata Gum Resin Extract

Boswellia serrata is a tree resin used in traditional medicine, mainly for joint pain and inflammation. Some studies suggest it may help with osteoart...

BosPure monograph & interactions

Other (inactive) ingredients: Sunflower Oil, Gelatin, Glycerin, Sunflower Lecithin, Water, Purified, Yellow Beeswax, Silica, Caramel color, Titanium Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

BosPro 500 mg by EuroMedica Drug Interactions

Want to check YOUR meds against BosPro 500 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
952Drugs
952 Moderate

Ingredients driving the most interactions

BosPure 952

Individual Drug Interactions

The ingredients in BosPro 500 mg interact with 952 drugs. Click any drug to see the details.

1 of the 1 ingredient in BosPro 500 mg interact with drugs. Each result below shows which ingredient is responsible. BosPure

Each ingredient & the kinds of drugs it affects

For each ingredient in BosPro 500 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

BosPure6 drug types · 952 drugs

Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, Boswellia serrata might increase the levels of CYP1A2 substrates.
In vitro research shows that Boswellia serrata gum resin inhibits CYP1A2 enzymes.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, Boswellia serrata might increase the levels of CYP2C19 substrates.
In vitro research shows that Boswellia serrata gum resin inhibits CYP2C19 enzymes.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, Boswellia serrata might increase the levels of CYP2C9 substrates.
In vitro research shows that Boswellia serrata gum resin inhibits CYP2C9 enzymes.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, Boswellia serrata might increase the levels of CYP2D6 substrates.
In vitro research shows that Boswellia serrata gum resin inhibits CYP2D6 enzymes.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, Boswellia serrata might increase or decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that Boswellia serrata gum resin inhibits CYP3A4 enzymes. Other in vitro research shows that Boswellia serrata extract inhibits CYP3A4 enzymes at most concentrations, although it may modestly induce enzyme activity at low concentrations.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, Boswellia serrata might alter the effects of immunosuppressive drugs.
Some in vitro research suggests that Boswellia serrata extracts might inhibit mediators of autoimmune disorders such as leukotrienes and reduce production of antibodies and cell-mediated immunity. However, other in vitro research suggests that, when coupled with calcium ions, boswellic acids containing the keto group have immunostimulant properties within specific cell signaling pathways.

Likelihood Possible Evidence D
BosPure full monograph & interactions
The maker

Brand information

Manufacturer and brand details for BosPro 500 mg, from the product label.

EuroMedica

See all EuroMedica products
Name
EuroMedica
Street Address
955 Challenger Drive
City
Green Bay
State
WI
ZipCode
54311
Phone Number
866-842-7256
Pharmacist Counseling Corner

BosPro 500 mg by EuroMedica: Common Questions

Does BosPro 500 mg by EuroMedica interact with any medications?
Yes. Based on its ingredients, BosPro 500 mg has a known interaction with 952 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
BosPro 500 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is boswellia serrata the same as frankincense?
Boswellia serrata is the tree that produces frankincense resin. BosPro contains the gum resin extract from this plant. If you're using frankincense in other forms (topical or aromatherapy), the safety and interaction profile may differ, so check the label.
Can I take BosPro if I'm pregnant?
No — there isn't enough safety data, so it's best avoided during pregnancy. If you're pregnant or planning to become pregnant, talk with your doctor or pharmacist before taking this supplement.
What if I'm breastfeeding?
Safety during breastfeeding is unknown, so it's best to avoid it. If you're nursing or thinking about nursing, check with your doctor or pharmacist first.
How often do people get side effects from boswellia?
The most common side effects — stomach pain, diarrhea, headache, heartburn, nausea — appear in a small number of trial participants. In one study, about 11% reported headache. Serious effects like bezoar formation are very rare.
Will BosPro help my hay fever?
The evidence for allergic rhinitis (hay fever) is insufficient to say whether it works. More research is needed. Osteoarthritis is the condition with the most reliable evidence behind boswellia, rated as possibly effective.
Does BosPro have any fillers?
The softgel contains inactive ingredients like sunflower oil, gelatin, glycerin, and silica that help form and preserve the capsule — these are standard in softgel products and help deliver the active ingredient.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if BosPro 500 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

BosPro 500 mg label
Go deeper

The Full Monographs Behind BosPro 500 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Boswellia Serrata

Interacts with 952 drugs

Boswellia serrata is a tree resin used in traditional medicine, mainly for joint pain and inflammation. Some studies suggest it may help with osteoarthritis symptoms, but the overall evidenc...

Read the full Boswellia Serrata monograph →
Sources

Sources & How We Checked

BosPro 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 16 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Boswellia Serrata 16 references
  1. Gupta I, Gupta V, Parihar A, et al. Effects of Boswellia serrata gum resin in patients with bronchial asthma: results of a double-blind, placebo-controlled, 6-week clinical study. Eur J Med Res 1998;3:511-4.
  2. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
  3. Kimmatkar N, Thawani V, Hingorani L, et al. Efficacy and tolerability of Boswellia serrata extract in treatment of osteoarthritis of knee--a randomized double blind placebo controlled trial. Phytomedicine 2003;10:3-7. PubMed
  4. Liu JJ, Nilsson A, Oredsson S, et al. Boswellic acids trigger apoptosis via a pathway dependent on caspase-8 activation but independent on Fas/Fas ligand interaction in colon cancer HT-29 cells. Carcinogenesis 2002;23:2087-93. PubMed
  5. Wildfeuer A, Neu IS, Safayhi H, et al. Effects of boswellic acids extracted from a herbal medicine on the biosynthesis of leukotrienes and the course of experimental autoimmune encephalomyelitis. Arzneimittelforschung 1998;48:668-74.
  6. Gupta I, Parihar A, Malhotra P, et al. Effects of gum resin of Boswellia serrata in patients with chronic colitis. Planta Med 2001;67:391-5. PubMed
  7. Sengupta K, Alluri KV, Satish AR, et al. A double blind, randomized, placebo controlled study of the efficacy and safety of 5-Loxin. Arthritis Res Ther 2008;10:R85.
  8. Sengupta K, Krishnaraju AV, Vishal AA, et al. Comparative efficacy and tolerability of 5-Loxin and Aflapin against osteoarthritis of the knee: a double blind, randomized, placebo controlled clinical study. Int J Med Sci 2010;7:366-77.
  9. Ernst E. Frankincense: systematic review. BMJ 2008;337:a2813. PubMed
  10. Kirste S, Treier M, Wehrle SJ, et al. Boswellia serratea extract acts on cerebral edema in patients irradiated for brain tumors: a prospective, randomized, placebo-controlled, double-blind pilot trial. Cancer 2011;117:3788-95.
  11. Frank A, Unger M. Analysis of frankincense from various Boswellia species with inhibitory activity on human drug metabolising cytochrome P450 enzymes using liquid chromatography mass spectrometry after automated on-line extraction. J Chromatogr A 2006;111 PubMed
  12. Altmann A, Poeckel D, Fischer L, et al. Coupling of boswellic acid-incuded Ca2+ mobilisation and MAPK activation to lipid metabolism and peroxide formation in human leucocytes. Br J Pharmacol 2004;141:223-32.
  13. El Fortia, M., Badi, H., Elalem, Kh, Kadiki, O., and Topov, Y. Olibanum bezoar: complication of a traditional popular medicine. East Mediterr.Health J 2006;12(6):927-929.
  14. Meshkat S, Mahmoodi Baram S, Rajaei S, et al. Boswellia serrata extract shows cognitive benefits in a double-blind, randomized, placebo-controlled pilot clinical trial in individuals who suffered traumatic brain injury. Brain Inj 2022;36(4):553-559. PubMed
  15. Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
  16. Valente IVB, Garcia D, Abbott A, et al. The anti-proliferative effects of a frankincense extract in a window of opportunity phase ia clinical trial for patients with breast cancer. Breast Cancer Res Treat 2024;204(3):521-530. PubMed

See these in context on the Boswellia Serrata monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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