Bronchial Wellness Syrup Ingredients & Drug Interactions
by GaiaKids
What is this page for?
First and foremost: checking Bronchial Wellness Syrup against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Bronchial Wellness Syrup is a dietary supplement by GaiaKids with 7 active ingredients. Its ingredients are commonly taken for digestive and liver complaints, bloating and gallbladder support, mild inflammation.Based on those ingredients, 246 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Orange peel essential oil, Lemon Peel. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Bronchial Wellness Syrup by GaiaKids
Ask about any prescription or over-the-counter medication and we check it for interactions with Bronchial Wellness Syrup by GaiaKids — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Bronchial Wellness Syrup by GaiaKids
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
The stated purpose hasn't been mapped to our evidence data yet.
Why this rating?
- We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.
Why this rating?
- The label discloses an exact amount for 2 of its 7 active ingredients.
- “Proprietary Blend” is a proprietary blend — the label gives one combined amount (20 mg) without saying how much of each component you get.
At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.
Why this rating?
- 2 of the 4 matched ingredients can interact with medications — Lemon, Sweet Orange.
- The most serious interaction on file is rated Major.
- For scale: 246 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.
Why this rating?
- We hold adverse-effect (side-effect) data for 3 of the 4 matched ingredients.
- Pregnancy & breastfeeding safety ratings cover 4 of 4.
- General safety write-ups exist for 4 of 4.
- Remember: this measures how much safety information exists. Thin data is not the same as being safe.
HelloPharmacist summaryFormula with limited ingredient disclosure with no assessable stated purpose. Major medication interactions have been identified, and safety information is well characterized.
Assessment coverage: 4 of 7 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 26, 2020.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Bronchial Wellness Syrup, straight from the product label.
| Brand | GaiaKids |
|---|---|
| Barcode (UPC) | 751063145039 |
| Net contents | 3 Fluid Ounce(s); 89 mL |
| Market status | Off market |
| Date entered into DSLD | Dec 26, 2020 |
| DSLD ID | 240697 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Children 4 or More Years of Age, Organic, Gluten Free, Dairy Free, Children more than 1 but less than 4 |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Bronchial Wellness Syrup by GaiaKids, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 20 Calorie(s), 20 Calorie(s) | -- |
| Total Carbohydrates | 5 Gram(s), 5 Gram(s) | 2%, 3% |
| Added Sugars | 5 Gram(s), 5 Gram(s) | 9%, 19% |
| Total Sugars | 5 Gram(s), 5 Gram(s) | -- |
| Proprietary Blend | 20 mg, 20 mg | -- |
| organic English Plantain leaf hydroalcoholic extract | 61 mg, 61 mg | -- |
| organic English Plantain leaf freeze-dried extract | 14 mg, 14 mg | -- |
| organic Grindelia flowering tops freeze-dried extract | 0 NP, 0 NP | -- |
| organic Helichrysum flowering tops freeze-dried extract | 0 NP, 0 NP | -- |
| Lemon Peel | 0 NP, 0 NP | -- |
| Orange peel essential oil | 0 NP, 0 NP | -- |
| Myrtle leaf essential oil | 0 NP, 0 NP | -- |
Other ingredients: Cane Sugar, organic Honey, Water, Lemon
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested Use Ages 2-6: 1 teaspoon 2 times daily Ages 6-11: 1 teaspoon up to 4 times daily Shake well before use.
Use within 1 month of opening.
Storage
Refrigerate upon opening.
Precautions
This product contains honey - not for use by children under 1 year old.
Do not use if cap seal is broken.
Store away from children.
If your child has a medical condition or takes medications, please consult with your doctor before use.
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Formulation
Immune Support
Certified Organic by Oregon Tilth
Dairy-free Gluten-free
Certified Organic
Bronchial Wellness Syrup is produced in Tuscany, Italy, by Aboca, the herbal supplement leader in Europe since 1978. Gaia Herbs' partnership with Aboca is born from a mutual belief in sustainable product development, dedication to quality, and a deep respect for science and nature working in harmony. Aboca
Immune support Supports overall throat & lung health for your little ones
Seals/Symbols
USDA Organic
Integrity Purity Potency EST 1987 USA
Certified B Corporation
FDA Statement of Identity
Herbal Supplement
General Statements
Gaia Herbs delivers unprecedented traceability by screening every product and sharing the results online. See for yourself, and learn more about your herbs, by entering the unique ID # below at meetyourherbs.com
Connecting plants & people since 1987 Purity - Keep it clean All products are screened for pesticides, microbes, & heavy metals. Integrity - Keep it real See the proof at meetyourherbs.com, the world's first herb traceability platform. Potency - Keep it strong Concentrated extracts provide a delicious & convenient way to get your daily dose of herbs. Discover our guiding truths at: @gaiaherbs A partnership of mutual beliefs
New look Same formula
Product of Italy
Formula
Supports overall throat & lung health for your little ones
Delicious herbal blend with Grindelia & organic honey
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Bronchial Wellness Syrup by GaiaKids label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Bronchial Wellness Syrup by GaiaKids
These are the 7 active ingredients this product is made of. Select any to open its full monograph.
Serving size5 mL Dosage formLiquid Servings per container18 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Blend
- › Organic Grindelia flowering tops freeze-dried extract
- › Organic Helichrysum flowering tops freeze-dried extract
- › Lemon Peel
- › Orange peel essential oil
- › Myrtle leaf essential oil
Organic English Plantain leaf hydroalcoholic extract
Organic English Plantain leaf freeze-dried extract
Other (inactive) ingredients: Cane Sugar, Organic Honey, Water, Lemon. These complete the product’s ingredient list but are not active constituents.
Bronchial Wellness Syrup by GaiaKids Drug Interactions
Bronchial Wellness Syrup contains 7 ingredients, and 2 of them have known drug interactions. Altogether they interact with 246 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against Bronchial Wellness Syrup?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Bronchial Wellness Syrup interact with 246 drugs. Click any drug to see the details.
2 of the 7 ingredients in Bronchial Wellness Syrup interact with drugs. Each result below shows which ingredient is responsible. Orange peel essential oil Lemon Peel
AtorvastatinAtorvaliq
How Atorvastatin interacts with Bronchial Wellness Syrup — through 1 ingredient. Tap an ingredient for the detail:
Orange Peel Essential OilOrganic Anion-transporting Polypeptide Substrates (oatp) Major
Interaction Summary
Consuming sweet orange juice can decrease oral absorption of OATP substrates.
Read the full Orange Peel Essential Oil + Atorvastatin interactionAtorvastatin CalciumLipitor
How Atorvastatin Calcium interacts with Bronchial Wellness Syrup — through 1 ingredient. Tap an ingredient for the detail:
Orange Peel Essential OilOrganic Anion-transporting Polypeptide Substrates (oatp) Major
Interaction Summary
Consuming sweet orange juice can decrease oral absorption of OATP substrates.
Read the full Orange Peel Essential Oil + Atorvastatin Calcium interactionBosentanTracleer
How Bosentan interacts with Bronchial Wellness Syrup — through 1 ingredient. Tap an ingredient for the detail:
Orange Peel Essential OilOrganic Anion-transporting Polypeptide Substrates (oatp) Major
Interaction Summary
Consuming sweet orange juice can decrease oral absorption of OATP substrates.
Read the full Orange Peel Essential Oil + Bosentan interactionBrincidofovirTembexa
How Brincidofovir interacts with Bronchial Wellness Syrup — through 1 ingredient. Tap an ingredient for the detail:
Orange Peel Essential OilOrganic Anion-transporting Polypeptide Substrates (oatp) Major
Interaction Summary
Consuming sweet orange juice can decrease oral absorption of OATP substrates.
Read the full Orange Peel Essential Oil + Brincidofovir interactionCeliprololCelicard
How Celiprolol interacts with Bronchial Wellness Syrup — through 1 ingredient. Tap an ingredient for the detail:
Orange Peel Essential OilCeliprolol (celicard), Organic Anion-transporting Polypeptide Substrates (oatp) +1 Major
Interaction Summary
Consuming sweet orange with celiprolol can decrease oral absorption of celiprolol.
Read the full Orange Peel Essential Oil + Celiprolol interactionCerivastatin SodiumBaycol
How Cerivastatin Sodium interacts with Bronchial Wellness Syrup — through 1 ingredient. Tap an ingredient for the detail:
Orange Peel Essential OilOrganic Anion-transporting Polypeptide Substrates (oatp) Major
Interaction Summary
Consuming sweet orange juice can decrease oral absorption of OATP substrates.
Read the full Orange Peel Essential Oil + Cerivastatin Sodium interactionCinoxacinCinobac
How Cinoxacin interacts with Bronchial Wellness Syrup — through 1 ingredient. Tap an ingredient for the detail:
Orange Peel Essential OilOrganic Anion-transporting Polypeptide Substrates (oatp), Quinolone Antibiotics Major
Interaction Summary
Consuming sweet orange juice can decrease oral absorption of OATP substrates.
Read the full Orange Peel Essential Oil + Cinoxacin interactionCiprofloxacinCiloxan, Cipro, Cipro IV, Cipro XR, Ciprobay, Otiprio
How Ciprofloxacin interacts with Bronchial Wellness Syrup — through 1 ingredient. Tap an ingredient for the detail:
Orange Peel Essential OilQuinolone Antibiotics, Organic Anion-transporting Polypeptide Substrates (oatp) Major
Interaction Summary
Calcium-fortified sweet orange juice might reduce quinolone absorption.
Read the full Orange Peel Essential Oil + Ciprofloxacin interactionCiprofloxacin, HydrocortisoneCipro HC Otic
How Ciprofloxacin, Hydrocortisone interacts with Bronchial Wellness Syrup — through 1 ingredient. Tap an ingredient for the detail:
Orange Peel Essential OilOrganic Anion-transporting Polypeptide Substrates (oatp) Major
Interaction Summary
Consuming sweet orange juice can decrease oral absorption of OATP substrates.
Read the full Orange Peel Essential Oil + Ciprofloxacin, Hydrocortisone interactionClinafloxacinClinafloxacin
How Clinafloxacin interacts with Bronchial Wellness Syrup — through 1 ingredient. Tap an ingredient for the detail:
Orange Peel Essential OilQuinolone Antibiotics, Organic Anion-transporting Polypeptide Substrates (oatp) Major
Interaction Summary
Calcium-fortified sweet orange juice might reduce quinolone absorption.
Read the full Orange Peel Essential Oil + Clinafloxacin interactionEnoxacinPenetrex
How Enoxacin interacts with Bronchial Wellness Syrup — through 1 ingredient. Tap an ingredient for the detail:
Orange Peel Essential OilOrganic Anion-transporting Polypeptide Substrates (oatp), Quinolone Antibiotics Major
Interaction Summary
Consuming sweet orange juice can decrease oral absorption of OATP substrates.
Read the full Orange Peel Essential Oil + Enoxacin interactionEtoposideEtopophos, VePesid, VP16
How Etoposide interacts with Bronchial Wellness Syrup — through 1 ingredient. Tap an ingredient for the detail:
Orange Peel Essential OilP-glycoprotein Substrates, Organic Anion-transporting Polypeptide Substrates (oatp) Major
Interaction Summary
Sweet orange juice seems to modulate P-glycoprotein (P-gp), which might affect the blood levels of P-gp substrates.
Read the full Orange Peel Essential Oil + Etoposide interactionEzetimibe, AtorvastatinLiptruzet
How Ezetimibe, Atorvastatin interacts with Bronchial Wellness Syrup — through 1 ingredient. Tap an ingredient for the detail:
Orange Peel Essential OilOrganic Anion-transporting Polypeptide Substrates (oatp) Major
Interaction Summary
Consuming sweet orange juice can decrease oral absorption of OATP substrates.
Read the full Orange Peel Essential Oil + Ezetimibe, Atorvastatin interactionFexofenadineAllegra
How Fexofenadine interacts with Bronchial Wellness Syrup — through 1 ingredient. Tap an ingredient for the detail:
Orange Peel Essential OilP-glycoprotein Substrates, Organic Anion-transporting Polypeptide Substrates (oatp) +1 Major
Interaction Summary
Sweet orange juice seems to modulate P-glycoprotein (P-gp), which might affect the blood levels of P-gp substrates.
Read the full Orange Peel Essential Oil + Fexofenadine interactionFexofenadine, PseudoephedrineAllegra D
How Fexofenadine, Pseudoephedrine interacts with Bronchial Wellness Syrup — through 1 ingredient. Tap an ingredient for the detail:
Orange Peel Essential OilFexofenadine (allegra), P-glycoprotein Substrates +1 Major
Interaction Summary
Consuming sweet orange juice with fexofenadine can decrease oral absorption of fexofenadine.
Read the full Orange Peel Essential Oil + Fexofenadine, Pseudoephedrine interactionFluvastatinLescol, Lescol XL
How Fluvastatin interacts with Bronchial Wellness Syrup — through 1 ingredient. Tap an ingredient for the detail:
Orange Peel Essential OilOrganic Anion-transporting Polypeptide Substrates (oatp) Major
Interaction Summary
Consuming sweet orange juice can decrease oral absorption of OATP substrates.
Read the full Orange Peel Essential Oil + Fluvastatin interactionGatifloxacinTequin, Tequin Injection
How Gatifloxacin interacts with Bronchial Wellness Syrup — through 1 ingredient. Tap an ingredient for the detail:
Orange Peel Essential OilOrganic Anion-transporting Polypeptide Substrates (oatp), Quinolone Antibiotics Major
Interaction Summary
Consuming sweet orange juice can decrease oral absorption of OATP substrates.
Read the full Orange Peel Essential Oil + Gatifloxacin interactionGemifloxacinFactive
How Gemifloxacin interacts with Bronchial Wellness Syrup — through 1 ingredient. Tap an ingredient for the detail:
Orange Peel Essential OilQuinolone Antibiotics, Organic Anion-transporting Polypeptide Substrates (oatp) Major
Interaction Summary
Calcium-fortified sweet orange juice might reduce quinolone absorption.
Read the full Orange Peel Essential Oil + Gemifloxacin interactionGlyburideAlbert Glyburide, Diabeta, Glycron, Glynase, Glynase PresTab, Micronase +1 more
How Glyburide interacts with Bronchial Wellness Syrup — through 1 ingredient. Tap an ingredient for the detail:
Orange Peel Essential OilOrganic Anion-transporting Polypeptide Substrates (oatp) Major
Interaction Summary
Consuming sweet orange juice can decrease oral absorption of OATP substrates.
Read the full Orange Peel Essential Oil + Glyburide interactionGlyburide, MetforminGlucovance
How Glyburide, Metformin interacts with Bronchial Wellness Syrup — through 1 ingredient. Tap an ingredient for the detail:
Orange Peel Essential OilOrganic Anion-transporting Polypeptide Substrates (oatp) Major
Interaction Summary
Consuming sweet orange juice can decrease oral absorption of OATP substrates.
Read the full Orange Peel Essential Oil + Glyburide, Metformin interactionGrepafloxacinRaxar
How Grepafloxacin interacts with Bronchial Wellness Syrup — through 1 ingredient. Tap an ingredient for the detail:
Orange Peel Essential OilOrganic Anion-transporting Polypeptide Substrates (oatp), Quinolone Antibiotics Major
Interaction Summary
Consuming sweet orange juice can decrease oral absorption of OATP substrates.
Read the full Orange Peel Essential Oil + Grepafloxacin interactionIrinotecanCamptosar, Onivyde
How Irinotecan interacts with Bronchial Wellness Syrup — through 1 ingredient. Tap an ingredient for the detail:
Orange Peel Essential OilOrganic Anion-transporting Polypeptide Substrates (oatp) Major
Interaction Summary
Consuming sweet orange juice can decrease oral absorption of OATP substrates.
Read the full Orange Peel Essential Oil + Irinotecan interactionIrinotecan Hydrochloride
How Irinotecan Hydrochloride interacts with Bronchial Wellness Syrup — through 1 ingredient. Tap an ingredient for the detail:
Orange Peel Essential OilOrganic Anion-transporting Polypeptide Substrates (oatp) Major
Interaction Summary
Consuming sweet orange juice can decrease oral absorption of OATP substrates.
Read the full Orange Peel Essential Oil + Irinotecan Hydrochloride interactionIsoniazid, Pyrazinamide, RifampinRifater
How Isoniazid, Pyrazinamide, Rifampin interacts with Bronchial Wellness Syrup — through 1 ingredient. Tap an ingredient for the detail:
Orange Peel Essential OilOrganic Anion-transporting Polypeptide Substrates (oatp) Major
Interaction Summary
Consuming sweet orange juice can decrease oral absorption of OATP substrates.
Read the full Orange Peel Essential Oil + Isoniazid, Pyrazinamide, Rifampin interactionIsoniazid, RifampinRifamate
How Isoniazid, Rifampin interacts with Bronchial Wellness Syrup — through 1 ingredient. Tap an ingredient for the detail:
Orange Peel Essential OilOrganic Anion-transporting Polypeptide Substrates (oatp) Major
Interaction Summary
Consuming sweet orange juice can decrease oral absorption of OATP substrates.
Read the full Orange Peel Essential Oil + Isoniazid, Rifampin interactionIvermectinMectizan, Sklice, Soolantra, Stromectol
How Ivermectin interacts with Bronchial Wellness Syrup — through 1 ingredient. Tap an ingredient for the detail:
Orange Peel Essential OilP-glycoprotein Substrates, Ivermectin (stromectol, Others) Major
Interaction Summary
Sweet orange juice seems to modulate P-glycoprotein (P-gp), which might affect the blood levels of P-gp substrates.
Read the full Orange Peel Essential Oil + Ivermectin interactionLevofloxacinLeva-pak, Levaquin, Levaquin Injection
How Levofloxacin interacts with Bronchial Wellness Syrup — through 1 ingredient. Tap an ingredient for the detail:
Orange Peel Essential OilOrganic Anion-transporting Polypeptide Substrates (oatp), Quinolone Antibiotics Major
Interaction Summary
Consuming sweet orange juice can decrease oral absorption of OATP substrates.
Read the full Orange Peel Essential Oil + Levofloxacin interactionLevofloxacin (ophthalmic)Levofloxacin
How Levofloxacin (ophthalmic) interacts with Bronchial Wellness Syrup — through 1 ingredient. Tap an ingredient for the detail:
Orange Peel Essential OilOrganic Anion-transporting Polypeptide Substrates (oatp), Quinolone Antibiotics Major
Interaction Summary
Consuming sweet orange juice can decrease oral absorption of OATP substrates.
Read the full Orange Peel Essential Oil + Levofloxacin (ophthalmic) interactionLomefloxacinMaxaquin
How Lomefloxacin interacts with Bronchial Wellness Syrup — through 1 ingredient. Tap an ingredient for the detail:
Orange Peel Essential OilOrganic Anion-transporting Polypeptide Substrates (oatp), Quinolone Antibiotics Major
Interaction Summary
Consuming sweet orange juice can decrease oral absorption of OATP substrates.
Read the full Orange Peel Essential Oil + Lomefloxacin interactionLovastatinAltocor, Mevacor
How Lovastatin interacts with Bronchial Wellness Syrup — through 1 ingredient. Tap an ingredient for the detail:
Orange Peel Essential OilOrganic Anion-transporting Polypeptide Substrates (oatp) Major
Interaction Summary
Consuming sweet orange juice can decrease oral absorption of OATP substrates.
Read the full Orange Peel Essential Oil + Lovastatin interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Bronchial Wellness Syrup with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Orange peel essential oil
Celiprolol (Celicard)
Consuming sweet orange with celiprolol can decrease oral absorption of celiprolol.
A pharmacokinetic study in healthy volunteers shows that celiprolol levels, after a single dose of 100 mg, are decreased by up to 90% in people who drink sweet orange juice 200 mL three times daily. It's not known if lower consumption of sweet orange juice will have the same effect. Theoretically, this occurs due to short-term inhibition of organic anion transporting polypeptide (OATP). Recommend separating drug administration and consumption of sweet orange by at least 4 hours.
Ivermectin (Stromectol, Others)
Consuming sweet orange juice with ivermectin can decrease the oral absorption of ivermectin.
A pharmacokinetic study in healthy volunteers shows that taking ivermectin orally with sweet orange juice 750 mL over 4 hours reduces the bioavailability of ivermectin. This effect does not seem to be related to effects on P-glycoprotein. The effect on ivermectin is more pronounced in males compared to females.
Organic Anion-Transporting Polypeptide Substrates (Oatp)
Consuming sweet orange juice can decrease oral absorption of OATP substrates. Separate administration by at least 4 hours.
Clinical research shows that consuming sweet orange juice inhibits OATP, which reduces bioavailability of oral drugs that are substrates of OATP. For example, sweet orange juice decreases bioavailability of fexofenadine, a substrate of OATP, by about 72% and of celiprolol, another OATP substrate, by up to 90%. Since sweet orange juice seems to affect OATP for a short time, recommend separating drug administration and consumption of sweet orange juice by at least 4 hours.
Pravastatin (Pravachol)
Consuming sweet orange juice with pravastatin can increase the absorption of pravastatin.
A small pharmacokinetic study in healthy volunteers shows that consuming sweet orange juice 800 mL over 3 hours, including before, during, and after taking pravastatin 10 mg, increases pravastatin levels by about 149%, without affecting pravastatin elimination. Theoretically this effect might be due to modulation of organic anion transporting polypeptides (OATPs) by sweet orange juice. Sweet orange juice does not seem to affect simvastatin levels, but it is not known if sweet orange affects any of the other statins.
Fexofenadine (Allegra)
Consuming sweet orange juice with fexofenadine can decrease oral absorption of fexofenadine.
Clinical research shows that coadministration of sweet orange juice 1200 mL decreases bioavailability of fexofenadine by about 72%. In an animal model, sweet orange juice decreased bioavailability of fexofenadine by 31%. Fexofenadine manufacturer data indicates that concomitant administration of sweet orange juice and fexofenadine results in larger wheal and flare sizes in research models. This suggests that sweet orange reduces the clinical response to fexofenadine. Theoretically, this occurs due to short-term inhibition of organic anion transporting polypeptide (OATP). Recommend separating drug administration and consumption of sweet orange by at least 4 hours.
P-Glycoprotein Substrates
Sweet orange juice seems to modulate P-glycoprotein (P-gp), which might affect the blood levels of P-gp substrates.
Animal and in vitro research suggest that orange juice extract inhibits drug efflux by P-gp, increasing absorption and levels of P-gp substrates. In contrast, pharmacokinetic research in humans shows that drinking large amounts of sweet orange juice decreases absorption and levels of the P-gp substrate celiprolol. This suggests that orange juice actually induces drug efflux by P-gp or affects drug levels by another mechanism such as inhibiting the gut drug transporter called organic anion transporting polypeptide (OATP). Until more is known, sweet orange juice should be used cautiously in people taking P-gp substrates.
Quinolone Antibiotics
Calcium-fortified sweet orange juice might reduce quinolone absorption.
Calcium binds to quinolones in the gut. Theoretically, the calcium in certain fortified orange juices can also bind to quinolone antibiotics and reduce their absorption and levels.
Lemon Peel
Itraconazole (Sporanox)
Theoretically, taking itraconazole capsules or tablets with a beverage containing lemon might increase the levels and clinical effects of itraconazole.
In one case report, dissolving itraconazole tablets in a small amount of specific beverages containing lemon prior to administration increased the level of itraconazole in a lung transplant patient. In this case, the increased bioavailability was desirable and was likely due to improved tablet dissolution in the acidic beverage.
Brand information
Manufacturer and brand details for Bronchial Wellness Syrup, from the product label.
Bronchial Wellness Syrup by GaiaKids: Common Questions
Does Bronchial Wellness Syrup by GaiaKids interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Bronchial Wellness Syrup is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Bronchial Wellness Syrup’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sandy Everlasting
Sandy Everlasting (Helichrysum arenarium) is a yellow-flowered plant used in traditional European herbal medicine, mainly for digestive and liver-related complaints. Human evidence for its b...
Read the full Sandy Everlasting monograph → Herb & supplement monographLemon
Interacts with 1 drugLemon is a common citrus fruit that is a good source of vitamin C and citric acid, and it is widely used in food, drinks, and home remedies. While it can support hydration and a healthy diet...
Read the full Lemon monograph → Herb & supplement monographSweet Orange
Interacts with 246 drugsSweet orange is a common citrus fruit that is a good source of vitamin C, fiber, and antioxidants, and is enjoyed as a food worldwide. Its peel and essential oil are used in aromatherapy and...
Read the full Sweet Orange monograph → Herb & supplement monographMyrtle
Myrtle (Myrtus communis) is a Mediterranean shrub used traditionally for respiratory, digestive, and skin complaints. Modern research is mostly limited to laboratory and small studies, so it...
Read the full Myrtle monograph →Sources & How We Checked
Bronchial Wellness Syrup's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 25 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Sandy Everlasting 3 references
Lemon 2 references
- Ruggenenti P, Caruso MR, Cortinovis M, et al. Fresh lemon juice supplementation for the prevention of recurrent stones in calcium oxalate nephrolithiasis: A pragmatic, prospective, randomised, open, blinded endpoint (PROBE) trial. EClinicalMedicine 2021;4 PubMed
- Umemura K, Katada Y, Nakagawa S, et al. Improved absorption of itraconazole tablet by co-administration with lemon beverages in a lung transplant recipient: A case report. J Infect Chemother 2022;28(8):1203-1207. PubMed
Sweet Orange 17 references
- Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
- FDA, CFSAN. FDA-approved potassium health claim notification for potassium containing foods. 2000. Available at: www.cfsan.fda.gov/~dms/hclm-k.html.
- Kurowska EM, Spence JD, Jordan J, et al. HDL-cholesterol-raising effect of orange juice in subjects with hypercholesterolemia. Am J Clin Nutr 2000;72:1095-100. PubMed
- Murry JJ, Healy MD. Drug-mineral interactions: a new responsibility for the hospital dietician. J Am Diet Assoc 1991;91:66-73.
- Bailey DG, Dresser GK, Munoz C, et al. Reduction of fexofenadine bioavailability by fruit juices. Clin Pharmacol Ther 2001;69:P21.
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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