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Dietary supplement

Burdock 500 mg Ingredients & Drug Interactions

by Nature's Answer

Burdock 500 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Burdock 500 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Burdock 500 mg is a dietary supplement by Nature's Answer with 1 active ingredient. Its ingredients are commonly taken for skin conditions like acne and eczema, digestive support, diuretic ('detox') and blood purifier.Based on those ingredients, 122 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Burdock. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Burdock 500 mg by Nature's Answer

Ask about any prescription or over-the-counter medication and we check it for interactions with Burdock 500 mg by Nature's Answer — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Burdock 500 mg by Nature's Answer

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: burdock root at 500 mg per capsule. Burdock is a root traditionally used in food and herbal medicine.

The capsules also contain three inactive ingredients—vegetable cellulose (the capsule itself), calcium silicate, and rice flour—which are fillers and binders.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Burdock product and its label doesn't state a use — see Burdock's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for burdock isn't established for the uses listed in our data. For acne, aging skin, breast cancer, the common cold, and eczema, we hold insufficient reliable evidence to rate whether it works.

If you're considering it for one of these conditions, talk it over with your doctor or pharmacist to see what the current research supports and whether it's right for you.

The evidence, ingredient by ingredient Burdock

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Burdock is generally well tolerated when eaten as a food and for short-term use in otherwise healthy adults, though human safety data are limited. Allergic reactions, including contact dermatitis (skin rash from contact) and anaphylaxis (a severe whole-body reaction), are rare but can happen.

A single case of liver injury was reported in someone taking a detox tea with burdock and other ingredients, though it's unclear which component caused it. There's also a small number of cases of contact dermatitis from prolonged use of burdock root oil or burdock plasters.

The safety data advise against taking medicinal amounts during pregnancy due to lack of safety information and possible effects on the uterus. Similarly, there isn't enough safety information to recommend medicinal use while breastfeeding—talk with your doctor or pharmacist for personalized advice if you're pregnant or nursing.

Side effects, ingredient by ingredient Burdock

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Burdock.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 122 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take blood thinners or antiplatelet drugs—such as warfarin, aspirin, clopidogrel, or similar medications—check with your doctor or pharmacist before starting this product. Burdock may theoretically increase bleeding risk with these drugs.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Burdock is a traditional herbal ingredient with a long history and limited adverse effects when used as a food. If you take blood thinners or antiplatelet drugs, you'll want to check with your doctor or pharmacist before starting.

The evidence for specific health claims isn't established yet. Pregnant and nursing people should talk with their own healthcare provider before using medicinal amounts.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Burdock 500 mg, straight from the product label.

Brand Nature's Answer
Barcode (UPC) 083000161346
Net contents 90 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Feb 25, 2019
DSLD ID 184579
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Burdock 500 mg by Nature's Answer, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
UPC/BARCODE
083000161346
IngredientAmount% DV
Burdock500 mg--

Other ingredients: Vegetable Cellulose, Calcium Silicate, Rice Flour

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Discover Nature's Answer and trust the Difference... The True Nature of Our Standards goes way beyond the herb...

Discover Nature's Answer

2017 Nature's Answer

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Storage

Store in a cool, dry place.

Seals/Symbols

K Parve

Formula

K Parve

General Statements

Since 1972 Supports Overall Health & Wellness

FDA Statement of Identity

Dietary Supplement

Formulation

Vegan

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take one (1) capsule twice a day with food or water.

Precautions

Warning: Keep Out of Reach of Children.

Do not use if safety seal is damaged or missing.

Do not use if you are pregnant or nursing. If you are taking any medications or have a medical condition, consult with your healthcare practitioner before use.

General

18134 Rev. 417

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Burdock 500 mg by Nature's Answer label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Burdock 500 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Burdock 500 mg by Nature's Answer

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Burdock

Interacts with
122 drugs
500 mg per serving

Burdock is a traditional herb most often used for skin problems and as a so-called 'blood purifier,' but high-quality human studies are lacking and mo...

Burdock monograph & interactions

Other (inactive) ingredients: Vegetable Cellulose, Calcium Silicate, Rice Flour. These complete the product’s ingredient list but are not active constituents.

Interaction report

Burdock 500 mg by Nature's Answer Drug Interactions

Want to check YOUR meds against Burdock 500 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
122Drugs
122 Moderate

Ingredients driving the most interactions

Burdock 122

Individual Drug Interactions

The ingredients in Burdock 500 mg interact with 122 drugs. Click any drug to see the details.

1 of the 1 ingredient in Burdock 500 mg interact with drugs. Each result below shows which ingredient is responsible. Burdock

Each ingredient & the kinds of drugs it affects

For each ingredient in Burdock 500 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Burdock1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.

In vitro research shows that lignans from burdock reduce rabbit platelet aggregation by inhibiting platelet activating factor. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Burdock full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Burdock 500 mg, from the product label.

Nature's Answer

See all Nature's Answer products
Name
Nature's Answer
Street Address
85 Commerce Drive
City
Hauppauge
State
NY
ZipCode
11788
Phone Number
(800) 439-2324
Web Address
www.naturesanswer.com
Pharmacist Counseling Corner

Burdock 500 mg by Nature's Answer: Common Questions

Does Burdock 500 mg by Nature's Answer interact with any medications?
Yes. Based on its ingredients, Burdock 500 mg has a known interaction with 122 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Burdock 500 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
The safety data advise against medicinal amounts during pregnancy because of lack of safety information and possible effects on the uterus. There also isn't enough safety data to recommend medicinal use while breastfeeding. Talk with your doctor or pharmacist for personalized advice if you're pregnant or nursing.
What are the side effects?
Burdock is generally well tolerated. Allergic reactions, including skin rash from contact (contact dermatitis) and severe whole-body allergic reactions (anaphylaxis), are rare. A small number of cases of skin rash have been reported, especially with prolonged use of burdock root oil or burdock plasters. One case of liver injury was reported with a detox tea containing burdock and other ingredients, though it's unclear which ingredient caused it.
Does this actually work for acne, eczema, or the other uses listed?
The evidence isn't established in our data for acne, aging skin, breast cancer, the common cold, or eczema. If you're interested in burdock for one of these conditions, talk with your doctor or pharmacist about what the current research supports.
Is this safe to take long-term?
Burdock is likely safe for short-term use in healthy adults, especially when eaten as a food. However, human safety data are limited, and we don't have good information on long-term use. Discuss with your doctor or pharmacist if you're thinking about taking it regularly for weeks or months.
What's in the capsule besides the burdock?
The capsule contains vegetable cellulose (the capsule material itself), calcium silicate, and rice flour. These are inactive ingredients—binders and fillers—not active parts of the product.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Burdock 500 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Burdock 500 mg label
Go deeper

The Full Monographs Behind Burdock 500 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Burdock

Interacts with 122 drugs

Burdock is a traditional herb most often used for skin problems and as a so-called 'blood purifier,' but high-quality human studies are lacking and most claims are not well proven. It is wid...

Read the full Burdock monograph →
Sources

Sources & How We Checked

Burdock 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Burdock 11 references
  1. Iwakami S, Wu JB, Ebizuka Y, Sankawa U. Platelet activating factor (PAF) antagonists contained in medicinal plants: lignans and sesquiterpenes. Chem Pharm Bull (Tokyo) 1992;40:1196-8. PubMed
  2. Sasaki Y, Kimura Y, Tsunoda T, Tagami H. Anaphylaxis due to burdock. Int J Dermatol 2003;42:472-3. PubMed
  3. Rhoads PM, Tong TG, Banner W Jr, Anderson R. Anticholinergic poisonings associated with commercial burdock root tea. J Toxicol Clin Toxicol 1984-85;22:581-4. PubMed
  4. Rodriguez P, Blanco J, Juste S, et al. Allergic contact dermatitis due to burdock (Arctium lappa). Contact Dermatitis 1995;33:134-5.
  5. Kassler, W. J., Blanc, P., and Greenblatt, R. The use of medicinal herbs by human immunodeficiency virus-infected patients. Arch Intern Med 1991;151(11):2281-2288. DOI
  6. Chan, Y. S., Cheng, L. N., Wu, J. H., Chan, E., Kwan, Y. W., Lee, S. M., Leung, G. P., Yu, P. H., and Chan, S. W. A review of the pharmacological effects of Arctium lappa (burdock). Inflammopharmacology. 2011;19(5):245-254. PubMed
  7. Breed, F. B. and Kuwabara, T. Burdock ophthalmia. Arch Ophthalmol 1966;75(1):16-20.
  8. Bryson, P. D., Watanabe, A. S., Rumack, B. H., and Murphy, R. C. Burdock root tea poisoning. Case report involving a commercial preparation. JAMA 5-19-1978;239(20):2157. DOI
  9. <p>Fletcher GF<span>, </span>Cantwell JD. Burdock root tea poisoning. JAMA <span>1978 Oct 6;240(15):1586.</span></p> DOI
  10. Latif A, Fichadiya H, Abid F, Capo G. Herbal Teas and Thrombocytopenia: A Curious Case of Yellow Dock and Burdock-Induced Thrombocytopenia. Eur J Case Rep Intern Med 2022;9(3):003247. PubMed
  11. Niazi B, Ahmed K, Ahmed M, Ali S, Song K, Elias S. Drug-Induced Liver Injury from Herbal Liver Detoxification Tea. Case Rep Gastroenterol 2022;16(3):612-617. PubMed

See these in context on the Burdock monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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