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Dietary supplement

Children's Chewable Probiotic Natural Grape Flavor Ingredients & Drug Interactions

by Trace Minerals

Children's Chewable Probiotic Natural Grape Flavor label
See full label image
Other (e.g. Tea Bag) Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Children's Chewable Probiotic Natural Grape Flavor against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Children's Chewable Probiotic Natural Grape Flavor is a dietary supplement by Trace Minerals with 2 active ingredients. Its ingredients are commonly taken for constipation and regularity, prebiotic gut health, blood sugar support.Based on those ingredients, 268 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Probiotic Proprietary Blend, Inulin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Children's Chewable Probiotic Natural Grape Flavor by Trace Minerals

Ask about any prescription or over-the-counter medication and we check it for interactions with Children's Chewable Probiotic Natural Grape Flavor by Trace Minerals — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Children's Chewable Probiotic Natural Grape Flavor by Trace Minerals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 5 active ingredients.
  • “Probiotic Proprietary Blend” is a proprietary blend — the label gives one combined amount (24 mg) without saying how much of each component you get.

This product has 5 active ingredients: four types of probiotic bacteria (live organisms that support gut health) plus inulin, a prebiotic fiber that feeds beneficial bacteria. The probiotics are Lactobacillus acidophilus, Bifidobacterium animalis lactis, Bifidobacterium infantis, and Bifidobacterium breve.

The inactive ingredients are xylitol, natural grape flavor, stearic acid, citric acid, silica, magnesium stearate, and steviol glycosides — these are the binders, sweeteners, and flavoring agents that make the chewables work.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: support healthy intestinal flora and immune function.
  • We looked for evidence on: Antibiotic-associated diarrhea, Colic, Constipation, Irritable bowel syndrome (IBS), Lactose intolerance, Respiratory tract infections — and 4 related terms.
  • The strongest evidence on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Antibiotic-associated diarrhea (Natural Medicines).
  • Also on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Irritable bowel syndrome (IBS).
  • Also on file: Inulin is rated "Possibly Effective" for Constipation.

The evidence for these ingredients is mixed. Lactobacillus acidophilus is possibly effective for irritable bowel syndrome, antibiotic-associated diarrhea, and bacterial vaginosis, and possibly effective for Helicobacter pylori infection.

Inulin is possibly effective for constipation and possibly effective for diabetes. Bifidobacterium breve shows insufficient evidence for most conditions we checked it against — the data just isn't there yet to say whether it works.

We don't have effectiveness data on file for Bifidobacterium animalis lactis or Bifidobacterium infantis.

The evidence, ingredient by ingredient Inulin Lactobacillus Acidophilus Bifidobacterium Breve

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lactobacillus acidophilus and Bifidobacterium breve are generally well tolerated in healthy children, though they can occasionally cause bloating, flatulence, or gastrointestinal discomfort. Inulin frequently causes gas and bloating, especially at higher doses, and can also cause diarrhea or constipation.

In rare cases, inulin has triggered anaphylaxis in people with inulin sensitivity. The probiotics themselves carry a theoretical but documented risk of infection in severely ill or immunocompromised children — this is uncommon but worth knowing.

We have no pregnancy or lactation data on file for Bifidobacterium animalis lactis, Bifidobacterium infantis, or Bifidobacterium breve. Inulin and Lactobacillus acidophilus are likely safe in pregnancy and lactation.

Side effects, ingredient by ingredient Inulin Lactobacillus Acidophilus Bifidobacterium Breve

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Lactobacillus Acidophilus, Inulin, Bifidobacterium Breve.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 268 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your pharmacist or doctor before starting if your child takes antibiotic drugs — time the doses apart. If your child takes antidiabetes medication, mention this product since inulin may theoretically lower blood sugar further.

Use the medication checker on this page for your child's complete list.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This is a reasonable probiotic for most healthy kids, especially those with constipation or recent antibiotic use. The main thing to watch: if your child is on antibiotics, don't give them at the same time — space them a few hours apart so the antibiotics don't kill the live bacteria.

If your child has diabetes or is severely ill or immunocompromised, talk to their doctor first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 22, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Children's Chewable Probiotic Natural Grape Flavor, straight from the product label.

Brand Trace Minerals
Barcode (UPC) 878941003271
Net contents 30 Chewable Wafer(s)
Market status On market
Date entered into DSLD Jun 22, 2023
DSLD ID 293813
Product type Other Combinations
Supplement form Other (e.g. Tea Bag)
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Children 4 or More Years of Age, Vegetarian, No Allergies, Gluten Free, Children more than 1 but less than 4
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Children's Chewable Probiotic Natural Grape Flavor by Trace Minerals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Chewable Wafer(s)
Maximum serving Sizes:
1 Chewable Wafer(s)
Servings per container
30
UPC/BARCODE
878941003271
IngredientAmount% DV
Inulin60 mg--
Lactobacillus acidophilus0 NP--
Bifidobacterium animalis lactis0 NP--
Bifidobacterium infantis0 NP--
Bifidobacterium breve0 NP--
Probiotic Proprietary Blend24 mg--

Other ingredients: Xylitol, natural Grape flavor, Stearic Acid, Citric Acid, Silica, Magnesium Stearate, Steviol Glycosides

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

3 Billion guaranteed - 4 Strains

Children's Chewable Probiotic is formulated especially for children and contains 4 natural probiotic strains of friendly, viable organisms to help support and maintain healthy intestinal flora balance.

Suggested/Recommended/Usage/Directions

One-a-day

Suggested use: Children age 2 and over take 1 chewable daily on an empty stomach.

FDA Statement of Identity

Dietary Supplement

Formulation

No known allergens. Gluten free.

A balance of healthy intestinal flora helps support the body's immune system and can help avoid occasional indigestion and digestive upset.

Gluten free Non GMO

Certified vegetarian

Storage

Refrigerate after opening. TMR guarantees probiotic potency of 3 billion CFUs per chewable at time of manufacture. For best results, keep product refrigerated to maintain probiotic potency.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Seals/Symbols

cGMP Certified 3rd Party tested

General Statements

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See for yourself

Children's Chewable Probiotic Natural Grape Flavor by Trace Minerals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Children's Chewable Probiotic Natural Grape Flavor label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Children's Chewable Probiotic Natural Grape Flavor by Trace Minerals

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Chewable Wafer(s) Dosage formOther (e.g. Tea Bag) Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Inulin

Interacts with
86 drugs
60 mg per serving

Inulin is a type of plant fiber (a prebiotic) found naturally in foods like chicory root, onions, and garlic, and it is widely added to supplements an...

Inulin monograph & interactions

Probiotic Proprietary Blend

Interacts with
182 drugs
24 mg per serving

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy p...

Probiotic Proprietary Blend monograph & interactions

Other (inactive) ingredients: Xylitol, Natural Grape flavor, Stearic Acid, Citric Acid, Silica, Magnesium Stearate, Steviol Glycosides. These complete the product’s ingredient list but are not active constituents.

Interaction report

Children's Chewable Probiotic Natural Grape Flavor by Trace Minerals Drug Interactions

Want to check YOUR meds against Children's Chewable Probiotic Natural Grape Flavor?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
268Drugs
182 Moderate 86 Minor

Ingredients driving the most interactions

Probiotic Proprietary Blend 182
Inulin 86

Individual Drug Interactions

The ingredients in Children's Chewable Probiotic Natural Grape Flavor interact with 268 drugs. Click any drug to see the details.

2 of the 2 ingredients in Children's Chewable Probiotic Natural Grape Flavor interact with drugs. Each result below shows which ingredient is responsible. Probiotic Proprietary Blend Inulin

Each ingredient & the kinds of drugs it affects

For each ingredient in Children's Chewable Probiotic Natural Grape Flavor with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Probiotic Proprietary Blend1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.

Likelihood Probable Evidence D
Probiotic Proprietary Blend full monograph & interactions

Inulin1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, inulin might increase the risk of hypoglycemia with antidiabetes drugs.
Some clinical research shows that inulin improves glycemic control in patients with diabetes; however, it is unclear if it has hypoglycemic effects.

Likelihood Unlikely Evidence D
Inulin full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Children's Chewable Probiotic Natural Grape Flavor, from the product label.

Trace Minerals

See all Trace Minerals products
Name
Trace Minerals
Street Address
P.O. Box 429
City
Roy
State
Utah
ZipCode
84067
Phone Number
(801) 731-6051
Web Address
www.traceminerals.com
Pharmacist Counseling Corner

Children's Chewable Probiotic Natural Grape Flavor by Trace Minerals: Common Questions

Does Children's Chewable Probiotic Natural Grape Flavor by Trace Minerals interact with any medications?
Yes. Based on its ingredients, Children's Chewable Probiotic Natural Grape Flavor has a known interaction with 268 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Children's Chewable Probiotic Natural Grape Flavor contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this probiotic work if my child is on antibiotics?
Not as well. Antibiotics kill the live probiotic organisms, so they won't survive in your child's gut. Ask the pharmacist or doctor to help you space the antibiotic and probiotic several hours apart — that way the antibiotic does its job first, then the probiotic can colonize afterward.
What side effects should I watch for?
Most commonly, bloating, gas, and changes in bowel movements — diarrhea or constipation. These are usually mild and temporary as the gut adjusts. Rarely, some kids report stomach discomfort. Anaphylaxis to inulin is very rare but has happened.
Is this safe during pregnancy or breastfeeding?
Inulin and Lactobacillus acidophilus are likely safe, but we don't have safety data on file for two of the Bifidobacterium strains in this blend. If you're pregnant or nursing, talk with your doctor or pharmacist before starting.
Can I give this to my child if they have diabetes?
Possibly, but check with their doctor first. Inulin may theoretically lower blood sugar, so their diabetes medication might need adjustment. It's an individual decision based on their blood sugar control.
What does inulin do in this product?
It's a prebiotic — a type of fiber that feeds the beneficial bacteria in the probiotic, helping them survive and work better in your child's gut. It's also possibly helpful for constipation on its own.
Is this a chewable or a capsule?
It's a chewable in grape flavor, so no swallowing a big pill — easier for kids. Just chew it and swallow.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Children's Chewable Probiotic Natural Grape Flavor is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Children's Chewable Probiotic Natural Grape Flavor label
Go deeper

The Full Monographs Behind Children's Chewable Probiotic Natural Grape Flavor’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Inulin

Interacts with 86 drugs

Inulin is a type of plant fiber (a prebiotic) found naturally in foods like chicory root, onions, and garlic, and it is widely added to supplements and processed foods. It may help with regu...

Read the full Inulin monograph → Herb & supplement monograph

Lactobacillus Acidophilus

Interacts with 182 drugs

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...

Read the full Lactobacillus Acidophilus monograph → Herb & supplement monograph

Bifidobacterium Breve

Interacts with 182 drugs

Bifidobacterium breve is a 'friendly' gut bacterium taken as a probiotic, most often to support digestion and balance the gut microbiome. Some studies suggest possible benefits for certain d...

Read the full Bifidobacterium Breve monograph →
Sources

Sources & How We Checked

Children's Chewable Probiotic Natural Grape Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 41 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Inulin 17 references
  1. Williams CM. Effects of inulin on lipid parameters in humans. J Nutr 1999 Jul;129(7 Suppl):1471S-3S. PubMed
  2. Pedersen A, Sandstrom B, Van Amelsvoort JM. The effect of ingestion of inulin on blood lipids and gastrointestinal symptoms in healthy females. Br J Nutr 1997;78:215-22. PubMed
  3. Cummings JH, Macfarlane GT, Englyst HN. Prebiotic digestion and fermentation. Am J Clin Nutr 2001;73:415S-420S. PubMed
  4. Bonnema AL, Kolberg LW, Thomas W, Slavin JL. Gastrointestinal tolerance of chicory inulin products. J Am Diet Assoc 2010;110(6):865-8. PubMed
  5. Dehghan P, Gargari BP, Jafar-Abadi MA, Aliasgharzadeh A. Inulin controls inflammation and metabolic endotoxemia in women with type 2 diabetes mellitus: a randomized-controlled clinical trial. Int J Food Sci Nutr 2014;65(1):117-23. PubMed
  6. Guess ND, Dornhorst A, Oliver N, Frost GS. A randomised crossover trial: the effect of inulin on glucose homeostasis in subtypes of prediabetes. Ann Nutr Metab 2016;68(1):26-34. PubMed
  7. Marteau P, Jacobs H, Cazaubiel M, Signoret C, Prevel JM, Housez B. Effects of chicory inulin in constipated elderly people: a double-blind controlled trial. Int J Food Sci Nutr 2011;62(2):164-70. PubMed
  8. Mensink MA, Frijlink HW, van der Voort Maarschalk K, Hinrichs WL. Inulin, a flexible oligosaccharide I: review of its physicochemical characteristics. Carbohydr Polym 2015;130:405-19. PubMed
  9. Slavin J, Feirtag J. Chicory inulin does not increase stool weight or speed up intestinal transit time in healthy male subjects. Food Funct. 2011;2(1):72-7. PubMed
  10. Micka A, Siepelmeyer A, Holz A, Theis S, Schön C. Effect of consumption of chicory inulin on bowel function in healthy subjects with constipation: a randomized, double-blind, placebo-controlled trial. Int J Food Sci Nutr. 2017;68(1):82-89. PubMed
  11. Smiljanec K, Mitchell CM, Privitera OF, Neilson AP, Davy KP, Davy BM. Pre-meal inulin consumption does not affect acute energy intake in overweight and obese middle-aged and older adults: A randomized controlled crossover pilot trial. Nutr Health. 2017;23 PubMed
  12. Cai X, Yu H, Liu L, et al. Milk powder co-supplemented with inulin and resistant dextrin improves glycemic control and insulin resistance in elderly type 2 diabetes mellitus: a 12-week randomized, double-blind, placebo-controlled trial. Mol Nutr Food Res PubMed
  13. Rao M, Gao C, Xu L, et al. Effect of inulin-type carbohydrates on insulin resistance in patients with type 2 diabetes and obesity: a systematic review and meta-analysis. J Diabetes Res. 2019;2019:5101423. PubMed
  14. Mitchell CM, Davy BM, Ponder MA, et al. Prebiotic Inulin Supplementation and Peripheral Insulin Sensitivity in adults at Elevated Risk for Type 2 Diabetes: A Pilot Randomized Controlled Trial. Nutrients 2021;13(9):3235. PubMed
  15. Li L, Li P, Xu L. Assessing the effects of inulin-type fructan intake on body weight, blood glucose, and lipid profile: A systematic review and meta-analysis of randomized controlled trials. Food Sci Nutr 2021;9(8):4598-4616. PubMed
  16. Ziaei R, Shahshahan Z, Ghasemi-Tehrani H, Heidari Z, Ghiasvand R. Effects of inulin-type fructans with different degrees of polymerization on inflammation, oxidative stress and endothelial dysfunction in women with polycystic ovary syndrome: A randomized,
  17. Risso D, Kaczmarczyk M, Laurie I, et al. Moderate intakes of soluble corn fibre or inulin do not cause gastrointestinal discomfort and are well tolerated in healthy children. Int J Food Sci Nutr 2022;73(8):1104-1115. PubMed

See these in context on the Inulin monograph →

Lactobacillus Acidophilus 15 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
  3. Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
  4. Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
  5. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  6. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  7. Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
  10. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  11. Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
  12. Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
  13. Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
  14. Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
  15. Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.

See these in context on the Lactobacillus Acidophilus monograph →

Bifidobacterium Breve 9 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
  3. Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
  4. Ohishi A, Takahashi S, Ito Y, et al. Bifidobacterium septicemia associated with postoperative probiotic therapy in a neonate with omphalocele. J Pediatr. 2010;156(4):679-81. PubMed
  5. Sakurai Y, Watanabe T, Miura Y, et al. Clinical and bacteriologic characteristics of six cases of Bifidobacterium breve bacteremia due to probiotic administration in the neonatal intensive care unit. Pediatr Infect Dis J 2022;41(1):62-65. PubMed
  6. Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed
  7. Wakabayashi Y, Nakayama S, Yamamoto A, et al. First case of necrotizing fasciitis and bacteremia caused by Bifidobacteriumbreve. Anaerobe 2022;76:102613.
  8. Takeda Y, Ota K, Kondo A, et al. A case of necrotizing fasciitis caused by Bifidobacterium breve. IDCases 2022;31:e01667. PubMed
  9. Suwantarat N, Romagnoli M, Wakefield T, Carroll KC. Ventriculoperitoneal shunt infection caused by Bifidobacterium breve. Anaerobe 2014;28:1-3. PubMed

See these in context on the Bifidobacterium Breve monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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