Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Chlorella 1000 mg Ingredients & Drug Interactions

by PipingRock.com

Other (e.g. Tea Bag) Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Chlorella 1000 mg is a dietary supplement by PipingRock.com with 2 active ingredients. Its ingredients are commonly taken for general nutrition and 'detox' support, immune support, liver and kidney support.Based on those ingredients, 337 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Chlorella. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Chlorella 1000 mg by PipingRock.com

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: chlorella, a freshwater algae at 1000 mg per serving. The inactive ingredients are dicalcium phosphate, stearic acid, cellulose, magnesium stearate, croscarmellose, silica, and cellulose coating — these are typical binders and flow agents that help hold the tablet together.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: General nutrition and superfood support.
  • We looked for evidence on: Fatigue, Hepatitis C, Hyperlipidemia, Metabolic syndrome, Nonalcoholic fatty liver disease (NAFLD), Pregnancy-related iron deficiency — and 3 related terms.
  • The strongest evidence on file: Chlorella is rated "Possibly Effective" for Pregnancy-related iron deficiency (Natural Medicines).
  • Also on file: Chlorella is rated "Insufficient Reliable Evidence To Rate" for Nonalcoholic fatty liver disease (NAFLD), Fatigue, Hepatitis C, Hyperlipidemia, and more.

Chlorella is possibly effective for pregnancy-related iron deficiency. For brain tumors, nonalcoholic fatty liver disease, depression, and fatigue, the evidence we have isn't solid enough to say whether it works.

If you're thinking of using it for one of those other reasons, we'd want you to talk with your doctor about whether it makes sense for your situation.

The evidence, ingredient by ingredient Chlorella

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Chlorella is generally well tolerated in the short term, though product quality varies a lot between manufacturers — that's worth keeping in mind. The most common side effects are allergic reactions, abdominal cramping, constipation, diarrhea, fatigue, gas, nausea, and changes in stool color, especially in the first couple of weeks.

Serious allergic reactions including anaphylaxis are rare but have been reported. We don't have enough long-term safety data, so avoid it unless your doctor says it's okay.

Side effects, ingredient by ingredient Chlorella

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Chlorella.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 337 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this, double-check with us if you're on warfarin (Coumadin) or any blood thinners — chlorella can reduce how well they work. Also flag any medications that make your skin sensitive to sunlight, since chlorella can add to that effect.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Chlorella might be worth considering if you have pregnancy-related iron deficiency and your doctor approves. If you take warfarin or any photosensitizing medication, you need to check with us first — the interactions are real.

Talk with your pharmacist about your full medication list before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 21, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Chlorella 1000 mg, straight from the product label.

Brand PipingRock.com
Net contents 120 Vegetarian Caplet(s)
Market status On market
Date entered into DSLD Jul 21, 2022
DSLD ID 272938
Product type Botanical
Supplement form Other (e.g. Tea Bag)
Dietary claims / uses All Other
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Chlorella 1000 mg by PipingRock.com, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Vegetarian Caplet(s)
Maximum serving Sizes:
3 Vegetarian Caplet(s)
Servings per container
40
IngredientAmount% DV
Calories10 Calorie(s)--
Total Carbohydrates0.5 Gram(s)1%
Protein1 Gram(s)--
Chlorella3000 mg--

Other ingredients: Dicalcium Phosphate, Stearic Acid, Cellulose, Magnesium Stearate, Croscarmellose, Silica, Cellulose Coating

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Dietary Supplement

Formulation

No gluten, non-GMO, vegetarian, no soy, no artificial color, no artificial flavor, no artificial sweetener, no preservatives, no wheat, no yeast, no milk, no lactose.

No gluten, non-GMO, vegetarian, no soy, no artificial color, no artificial flavor, no artificial sweetener, no preservatives, no wheat, no yeast, no milk, no lactose.

Green Superfood

Suggested/Recommended/Usage/Directions

Directions: For adults, take 3 vegetarian caplets daily, preferably with a meal.

Precautions

Warning: If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use.

If any adverse reactions occur, immediately stop using this product and consult your doctor. If seal under cap is damaged or missing, do not use.

Keep out of reach of children.

Storage

Store in a cool, dry place.

See for yourself

Chlorella 1000 mg by PipingRock.com label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Chlorella 1000 mg by PipingRock.com

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size3 Vegetarian Caplet(s) Dosage formOther (e.g. Tea Bag) Servings per container40 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Protein

1 Gram(s) per serving

Chlorella

Interacts with
337 drugs
3000 mg per serving

Chlorella is a nutrient-rich freshwater green algae taken as a supplement for general wellness, immune support, and 'detox.' Some small studies sugges...

Chlorella monograph & interactions

Other (inactive) ingredients: Dicalcium Phosphate, Stearic Acid, Cellulose, Magnesium Stearate, Croscarmellose, Silica, Cellulose Coating. These complete the product’s ingredient list but are not active constituents.

Interaction report

Chlorella 1000 mg by PipingRock.com Drug Interactions

Want to check YOUR meds against Chlorella 1000 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
337Drugs
337 Moderate

Ingredients driving the most interactions

Chlorella 337

Each ingredient & the kinds of drugs it affects

For each ingredient in Chlorella 1000 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Chlorella2 drug types · 337 drugs

Photosensitizing Drugs

Theoretically, chlorella might have additive effects with photosensitizing drugs.
Chlorella has been reported to cause photosensitization. In five case reports, patients who had ingested chlorella exhibited swelling followed by erythematopurpuric lesions on sun-exposed areas of the body. Theoretically, concomitant use with photosensitizing drugs may exacerbate effects.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, chlorella might reduce the clinical effects of warfarin.
Chlorella contains significant amounts of vitamin K. There is at least one case report of warfarin therapy becoming sub-therapeutic after initiation of chlorella supplements.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Chlorella 1000 mg, from the product label.

PipingRock.com

See all PipingRock.com products
Name
PipingRock
Web Address
PipingRock.com
Pharmacist Counseling Corner

Chlorella 1000 mg by PipingRock.com: Common Questions

Does Chlorella 1000 mg by PipingRock.com interact with any medications?
Yes. Based on its ingredients, Chlorella 1000 mg has a known interaction with 337 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Chlorella 1000 mg contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while I'm pregnant?
Chlorella is rated possibly safe during pregnancy, but we don't have a lot of data. Talk with your doctor or pharmacist about whether it's right for you — they'll know your full picture.
What are the side effects I might notice?
Most common ones are stomach cramping, constipation, diarrhea, nausea, and gas, especially in the first two weeks. Your stool color might change too. Allergic reactions can happen, and in rare cases, severe ones like anaphylaxis — if that occurs, get emergency care right away.
Does chlorella actually work for what I want to use it for?
The clearest evidence we have is for pregnancy-related iron deficiency — it's possibly effective. For fatigue, depression, liver issues, or brain tumors, we don't have enough reliable evidence to say it works. Ask your doctor if it makes sense for your specific reason.
Will this work if I'm on warfarin?
Not safely without checking first. Chlorella contains a lot of vitamin K, which can make warfarin less effective — there's even a case report of someone's warfarin failing after starting chlorella. We need to talk through this with you and your doctor.
Are there any fillers or extra stuff in here?
It's one active ingredient — chlorella — plus inactive binders and capsule materials like cellulose, magnesium stearate, and silica. Those are standard and needed to make the tablet work.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Chlorella 1000 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Chlorella 1000 mg label
Sources

Sources & How We Checked

Chlorella 1000 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 13 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Chlorella 13 references
  1. Peirce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York, NY: William Morrow and Co., 1999.
  2. Ng TP, Tan WC, Lee YK. Occupational asthma in a pharmacist induced by chlorella, a unicellular algae preparation. Resp Med 1994;88:555-7. PubMed
  3. Jitsukawa K, Suizu R, Hidano A. Chlorella photosensitization. New phytophotodermatosis. Int J Dermatol 1984;23:263-8. PubMed
  4. Merchant RE, Carmack CA, Wise CM. Nutritional supplementation with Chlorella pyrenoidosa for patients with fibromyalgia syndrome: a pilot study. Phytother Res 2000;14:167-73.
  5. Merchant RE, Rice CD, Young HF. Dietary Chlorella pyrenoidosa for patients with malignant glioma: effects on immunocompetence, quality of life, and survival. Phytother Res 1990;4:220-31.
  6. Halperin SA, Smith B, Nolan C, et al. Safety and immunoenhancing effect of a Chlorella-derived dietary supplement in healthy adults undergoing influenza vaccination: randomized, double-blind, placebo-controlled trial. CMAJ 2003;169:111-7..
  7. Ohtake, T., Negishi, K., Okamoto, K., Oka, M., Maesato, K., Moriya, H., and Kobayashi, S. Manganese-induced Parkinsonism in a patient undergoing maintenance hemodialysis. Am J Kidney Dis 2005;46(4):749-753. PubMed
  8. Ng, T. P., Tan, W. C., and Lee, Y. K. Occupational asthma in a pharmacist induced by Chlorella, a unicellular algae preparation. Respir.Med. 1994;88(7):555-557. PubMed
  9. Ohkawa, S., Yoneda, Y., Ohsumi, Y., and Tabuchi, M. [Warfarin therapy and chlorella]. Rinsho Shinkeigaku 1995;35(7):806-807.
  10. Azocar J, Diaz A. Efficacy and safety of chlorella supplementation in adults with chronic hepatitis C virus infection. World J Gastroenterol 2013;19(7):1085-90. PubMed
  11. Panahi Y, Badeli R, Karami GR, Badeli Z, Sahebkar A. A randomized controlled trial of 6-week Chlorella vulgaris supplementation in patients with major depressive disorder. Complement Ther Med 2015;23(4):598-602. PubMed
  12. Nakano S, Takekoshi H, Nakano M. Chlorella pyrenoidosa supplementation reduces the risk of anemia, proteinuria and edema in pregnant women. Plant Foods Hum Nutr 2010;65(1):25-30. PubMed
  13. Yavasoglu I, Turgutkaya A, Bolaman Z. Chlorella-induced thrombocytopenia. Sao Paulo Med J 2018;136(6):602-3. PubMed

See these in context on the Chlorella monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring