Interactions on record — worth a quick check against your medications. Based on 3 of 6 ingredients. Check your meds →
Dietary supplement

Clean BCAAs Watermelon Ingredients & Drug Interactions

by BSN

Powder Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Clean BCAAs Watermelon is a dietary supplement by BSN with 6 active ingredients. Its ingredients are commonly taken for common cold and immune support, antioxidant support, skin health and collagen formation.Based on those ingredients, 428 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Vitamin C, micronized Taurine, L-Glutamine, Micronized. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Clean BCAAs Watermelon by BSN

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Partial disclosure
Ingredient Transparency · database check
Partial

Most active ingredients list an amount, but at least one is hidden in a blend or missing.

Why this rating?
  • The label discloses an exact amount for 3 of its 6 active ingredients.
  • “Micronized BCAA Blend” is a proprietary blend — the label gives one combined amount (3 Gram(s)) without saying how much of each component you get.

Clean BCAAs Watermelon contains 6 active ingredients: three branched-chain amino acids (BCAAs) — L-Leucine, L-Isoleucine, and L-Valine — plus vitamin C, micronized taurine, and micronized L-Glutamine. The BCAAs are amino acids that play a role in muscle protein synthesis and recovery.

The product also contains inactive ingredients like malic acid, citric acid, natural and artificial flavors, sucralose, and silica — these are fillers and flavor agents.

Does it work?

Leans against
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Leans against

The strongest graded evidence we hold for the stated purpose leans against a benefit.

Why this rating?
  • The label markets this product for: muscle recovery and athletic performance.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle damage, Exercise-induced muscle soreness, Muscular endurance, Sports recovery, Strength training adaptation.
  • The closest evidence on file: Glutamine is rated "Possibly Ineffective" for Athletic performance (Natural Medicines).
  • Also on file: Glutamine is rated "Insufficient Reliable Evidence To Rate" for Exercise-induced muscle damage.
  • Also on file: Vitamin C is rated "Insufficient Reliable Evidence To Rate" for Athletic performance, Exercise-induced muscle damage.

The effectiveness evidence in our data varies by ingredient. Vitamin C is rated Effective for vitamin C deficiency and Possibly Effective for several other conditions including anemia of chronic disease, atrial fibrillation, cataracts, and exercise-induced respiratory infections.

L-Glutamine is rated Effective for sickle cell disease and Possibly Effective for HIV/AIDS-related wasting, postoperative recovery, and critical illness. Taurine is rated Possibly Effective for hepatitis and congestive heart failure, though also Possibly Ineffective for obesity.

We have no effectiveness data on file for the three branched-chain amino acids themselves in this product.

The evidence, ingredient by ingredient Vitamin C Taurine Glutamine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Vitamin C is generally well tolerated at normal dietary and supplement doses, though very high doses above 2 grams daily can cause abdominal cramps, heartburn, diarrhea, nausea, and other side effects — and high doses may increase kidney stone risk in susceptible people. During pregnancy and lactation, normal amounts from food and prenatal vitamins are considered safe, but high-dose supplements should be avoided unless advised by your doctor.

Taurine is generally well tolerated in typical doses, with constipation and diarrhea being the most common side effects; it's likely safe in pregnancy and lactation. L-Glutamine is also generally well tolerated, though it can cause bloating, flatulence, constipation, diarrhea, nausea, and headache — and it's rated likely safe in pregnancy and lactation.

Long-term safety data for taurine and glutamine supplements is less established, so use caution with prolonged use.

Side effects, ingredient by ingredient Vitamin C Taurine Glutamine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Glutamine, Vitamin C, Taurine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; seizure medications; cancer treatments; lithium.
  • For scale: 428 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you take estrogens (including birth control or hormone replacement therapy — vitamin C may increase their blood levels), blood thinners like warfarin, antihypertensive drugs (blood pressure medications — taurine may lower blood pressure further), or lithium (taurine may raise levels). Also flag if you take chemotherapy drugs, anticonvulsants, antipsychotics like fluphenazine, HIV medications like indinavir, thyroid medications like levothyroxine, or aluminum-containing products.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glancePartially disclosed formula with graded evidence leaning against its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Clean BCAAs Watermelon is a BCAA supplement with added vitamin C, taurine, and glutamine. If you take estrogen-based contraceptives, blood thinners like warfarin, antipsychotics, anticonvulsants, blood pressure medications, lithium, or chemotherapy drugs, you should check your exact medications with your doctor or pharmacist before starting this product.

Otherwise, for most healthy adults without kidney or liver disease, the ingredients are generally well tolerated at typical doses.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 22, 2016.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Clean BCAAs Watermelon, straight from the product label.

Brand BSN
Barcode (UPC) 834266002627
Net contents 8.47 oz.; 240 Gram(s)
Market status On market
Date entered into DSLD Apr 22, 2016
DSLD ID 58287
Product type Other Combinations
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Clean BCAAs Watermelon by BSN, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
8 Gram(s)
Maximum serving Sizes:
8 Gram(s)
Servings per container
30
UPC/BARCODE
834266002627
IngredientAmount% DV
Calories5 {Calories}--
Total Carbohydrates1 Gram(s)1%
L-Leucine0 NP--
L-Isoleucine0 NP--
L-Valine0 NP--
Vitamin C60 mg100%
micronized Taurine500 mg--
L-Glutamine, Micronized500 mg--
Micronized BCAA Blend3 Gram(s)--

Other ingredients: Natural & Artificial flavors, Malic Acid, Citric Acid, Calcium Silicate, Silicon Dioxide, Sucralose, Lecithin, Tartaric Acid, Acesulfame Potassium

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Seals/Symbols

BANNED SUBSTANCE TESTED

INFORMED CHOICE.org Trusted by sport

GF Gluten-Free

Formulation

Gluten-Free

For performance minded individuals looking for a premium supplement line that is free of FD&C Dyes, fillers, gluten, and other non-desirable ingredients, BSN's CLEAN Elite Athlete Series has you covered with everything you need and nothing you don't.

General Statements

Everything you need, nothing you don't

BCAAs Advanced Recovery Formula ~ Supports Muscular Endurance ~ Supports Recovery ~ Support Performance

Intended for use in healthy adults as part of a healthy, balanced diet and exercise program.

Informed-Choice is a quality assurance program for sports nutrition products. The program certifies that nutritional supplements that bear the Informed-Choice logo have been tested for banned substances by the world class sports anti-doping lab, LGC Limited.

Advanced Recovery Formula

Endurance* Recovery* Performance*

Naturally & Artificially Flavored

Contents sold by weight not volume.

Made in the USA This product contains ingredients of domestic and foreign origin.

Precautions

Warning: Consult your physician before using this product if you are taking any medications or are under a physician's care for a medical condition. Not for use by those under the age of 18, or women that are pregnant, trying to get pregnant, or nursing.

Not for use by those under the age of 18, or women that are pregnant, trying to get pregnant, or nursing.

Allergen information: Contains Soy (Lecithin) Ingredients.

Suggested/Recommended/Usage/Directions

Directions: Mix 1 scoop with 8-10 oz. of cold water before, during, or after training.

Brand IP Statement(s)

Finish First.

FDA Statement of Identity

Dietary Supplement

General

V.1.262.0315US 6030224

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formula

Allergen information: Contains Soy (Lecithin) Ingredients.

Storage

Store in a cool dry place away from direct sunlight.

See for yourself

Clean BCAAs Watermelon by BSN label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Clean BCAAs Watermelon by BSN

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size8 Gram(s) Dosage formPowder Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Vitamin C

Interacts with
207 drugs
60 mg per serving Form: Ascorbic Acid

Vitamin C (ascorbic acid) is an essential nutrient your body needs but cannot make, so you must get it from food or supplements. It's important for im...

Vitamin C monograph & interactions

Micronized Taurine

Interacts with
173 drugs
500 mg per serving

Taurine is an amino acid your body makes naturally and that you also get from animal foods. It is widely used in energy drinks and sports supplements,...

Micronized Taurine monograph & interactions

L-Glutamine, Micronized

Interacts with
50 drugs
500 mg per serving

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle c...

L-Glutamine, Micronized monograph & interactions

Micronized BCAA Blend

3 Gram(s) per serving
  • › L-Leucine
  • › L-Isoleucine
  • › L-Valine

Other (inactive) ingredients: Natural & Artificial flavors, Malic Acid, Citric Acid, Calcium Silicate, Silicon Dioxide, Sucralose, Lecithin, Tartaric Acid, Acesulfame Potassium. These complete the product’s ingredient list but are not active constituents.

Interaction report

Clean BCAAs Watermelon by BSN Drug Interactions

Want to check YOUR meds against Clean BCAAs Watermelon?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
428Drugs
323 Moderate 105 Minor

Ingredients driving the most interactions

Vitamin C 207

Each ingredient & the kinds of drugs it affects

For each ingredient in Clean BCAAs Watermelon with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin C13 drug types · 207 drugs

Alkylating Agents

Theoretically, antioxidant effects of vitamin C might reduce the effectiveness of alkylating agents.
The use of antioxidants like vitamin C during chemotherapy is controversial. There is concern that antioxidants could reduce the activity of chemotherapy drugs that generate free radicals, such as cyclophosphamide, chlorambucil, carmustine, busulfan, and thiotepa. In contrast, some researchers theorize that antioxidants might make chemotherapy more effective by reducing oxidative stress that could interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effect, if any, antioxidants such as vitamin C have on chemotherapy.

Likelihood Possible Evidence D
Aluminum

Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Research in animals and humans shows that vitamin C increases aluminum absorption, theoretically by chelating aluminum and keeping it in solution where it is available for absorption. In people with normal renal function, urinary excretion of aluminum will likely increase, making aluminum retention and toxicity unlikely. Patients with renal failure who take aluminum-containing compounds such as phosphate binders should avoid vitamin C supplements in doses above the recommended dietary allowances.

Likelihood Probable Evidence B
Antitumor Antibiotics

Theoretically, the antioxidant effects of vitamin C might reduce the effectiveness of antitumor antibiotics.
The use of antioxidants like vitamin C during chemotherapy is controversial. There is concern that antioxidants could reduce the activity of chemotherapy drugs which generate free radicals, such as doxorubicin. In contrast, some researchers theorize that antioxidants might make chemotherapy more effective by reducing oxidative stress that could interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effects, if any, antioxidants such as vitamin C have on chemotherapy.

Likelihood Possible Evidence D
Estrogens

Vitamin C might increase blood levels of estrogens.
Increases in plasma estrogen levels of up to 55% occur under some circumstances when vitamin C is taken concurrently with oral contraceptives or hormone replacement therapy, including topical products. It is suggested that vitamin C prevents oxidation of estrogen in the tissues, regenerates oxidized estrogen, and reduces sulfate conjugation of estrogen in the gut wall. When tissue levels of vitamin C are high, these processes are already maximized and supplemental vitamin C does not have any effect on estrogen levels. Increases in plasma estrogen levels may occur when patients who are deficient in vitamin C take supplements. Monitor these patients for estrogen-related side effects.

Likelihood Probable Evidence B
Fluphenazine (Prolixin)

Theoretically, vitamin C might decrease levels of fluphenazine.
In one patient there was a clinically significant decrease in fluphenazine levels when vitamin C (500 mg twice daily) was started. The mechanism is not known, and there is no further data to confirm this interaction.

Likelihood Possible Evidence D
Indinavir (Crixivan)

Vitamin C can modestly reduce indinavir levels.
One pharmacokinetic study shows that taking vitamin C 1 gram orally once daily along with indinavir 800 mg orally three times daily reduces the area under the concentration-time curve of indinavir by 14%. The mechanism of this interaction is unknown, but it is unlikely to be clinically significant in most patients. The effect of higher doses of vitamin C on indinavir levels is unknown.

Likelihood Probable Evidence B
Levothyroxine (Synthroid, Others)

Vitamin C can increase levothyroxine absorption.
Two clinical studies in adults with poorly controlled hypothyroidism show that swallowing levothyroxine with a glass of water containing vitamin C 500-1000 mg in solution reduces thyroid stimulating hormone (TSH) levels and increases thyroxine (T4) levels when compared with taking levothyroxine alone. This suggests that vitamin C increases the oral absorption of levothyroxine, possibly due to a reduction in pH.

Likelihood Probable Evidence B
Warfarin (Coumadin)

High-dose vitamin C might reduce the levels and effectiveness of warfarin.
Vitamin C in high doses may cause diarrhea and possibly reduce warfarin absorption. There are reports of two people who took up to 16 grams daily of vitamin C and had a reduction in prothrombin time. Lower doses of 5-10 grams daily can also reduce warfarin absorption. In many cases, this does not seem to be clinically significant. However, a case of warfarin resistance has been reported for a patient who took vitamin C 500 mg twice daily. Cessation of vitamin C supplementation resulted in a rapid increase in international normalized ratio (INR). Tell patients taking warfarin to avoid taking vitamin C in excessively high doses (greater than 10 grams daily). Lower doses may be safe, but the anticoagulation activity of warfarin should be monitored. Patients who are stabilized on warfarin while taking vitamin C should avoid adjusting vitamin C dosage to prevent the possibility of warfarin resistance.

Likelihood Possible Evidence D
Acetaminophen (Tylenol, Others)

High-dose vitamin C might slightly prolong the clearance of acetaminophen.
A small pharmacokinetic study in healthy volunteers shows that taking high-dose vitamin C (3 grams) 1.5 hours after taking acetaminophen 1 gram slightly increases the apparent half-life of acetaminophen from around 2.3 hours to 3.1 hours. Ascorbic acid competitively inhibits sulfate conjugation of acetaminophen. However, to compensate, elimination of acetaminophen glucuronide and unconjugated acetaminophen increases. This effect is not likely to be clinically significant.

Likelihood Probable Evidence B
Aspirin

Acidification of the urine by vitamin C might increase aspirin levels.
It has been suggested that acidification of the urine by vitamin C could increase reabsorption of salicylates by the renal tubules, and increase plasma salicylate levels. However, short-term use of up to 6 grams daily of vitamin C does not seem to affect urinary pH or salicylate excretion, suggesting this interaction is not clinically significant.

Likelihood Possible Evidence B
Choline Magnesium Trisalicylate (Trilisate)

Acidification of the urine by vitamin C might increase choline magnesium trisalicylate levels.
It has been suggested that acidification of the urine by vitamin C could increase reabsorption of salicylates by the renal tubules, and increase plasma salicylate levels. However, short-term use of up to 6 grams daily of vitamin C does not seem to affect urinary pH or salicylate excretion, suggesting this interaction probably is not clinically significant.

Likelihood Possible Evidence B
Niacin

Vitamin C might decrease the beneficial effects of niacin on high-density lipoprotein (HDL) cholesterol levels.
A combination of niacin and simvastatin (Zocor) effectively raises HDL cholesterol levels in patients with coronary disease and low HDL levels. Clinical research shows that taking a combination of antioxidants (vitamin C, vitamin E, beta-carotene, and selenium) along with niacin and simvastatin (Zocor) attenuates this rise in HDL, specifically the HDL-2 and apolipoprotein A1 fractions, by more than 50% in patients with coronary disease. It is not known whether this adverse effect is due to a single antioxidant such as vitamin C, or to the combination. It also is not known whether it will occur in other patient populations.

Likelihood Possible Evidence A
Salsalate (Disalcid)

Acidification of the urine by vitamin C might increase salsalate levels.
It has been suggested that acidification of the urine by vitamin C could increase reabsorption of salicylates by the renal tubules, and increase plasma salicylate levels. However, short-term use of up to 6 grams/day vitamin C does not seem to affect urinary pH or salicylate excretion, suggesting this interaction probably is not clinically significant.

Likelihood Possible Evidence B

micronized Taurine2 drug types · 173 drugs

Antihypertensive Drugs

Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.
Some clinical evidence suggests that taurine can reduce both systolic and diastolic blood pressure.

Likelihood Probable Evidence D
Lithium

Theoretically, taurine might reduce excretion and increase plasma levels of lithium.
Taurine is thought to have diuretic properties, which might reduce the excretion of lithium.

Likelihood Probable Evidence D

L-Glutamine, Micronized1 drug type · 50 drugs

Anticonvulsants

Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Glutamine is metabolized to the excitatory neurotransmitter glutamate. Glutamate might have antagonistic effects with anticonvulsant drugs. However, this interaction has not yet been reported in humans.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Clean BCAAs Watermelon, from the product label.

BSN

See all BSN products
Name
Bio-Engineered Supplements & Nutrition, Inc.
Street Address
975 Meridian Lake Dr.
City
Aurora
State
IL
ZipCode
60504
Phone Number
877-673-3727
Web Address
goBSN.com
Pharmacist Counseling Corner

Clean BCAAs Watermelon by BSN: Common Questions

Does Clean BCAAs Watermelon by BSN interact with any medications?
Yes. Based on its ingredients, Clean BCAAs Watermelon has a known interaction with 428 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Clean BCAAs Watermelon contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help with muscle recovery after workouts?
The product contains branched-chain amino acids (BCAAs), which play a role in muscle protein synthesis, though we hold no specific effectiveness data for the BCAAs themselves in our monographs. Many athletes use BCAAs for recovery, but talk with your doctor or trainer about whether it's right for your goals.
Can I take this if I'm pregnant?
Vitamin C at normal amounts is likely safe in pregnancy, and glutamine and taurine are also rated likely safe. However, the safety data for all the ingredients together at the doses in this product isn't fully established, so check with your doctor or pharmacist before taking it during pregnancy.
What side effects might I experience?
The most common side effects from the ingredients we have data for are gastrointestinal — bloating, flatulence, constipation, diarrhea, and nausea. These are generally mild and dose-related. At very high doses, vitamin C can also cause headache and heartburn.
Is this safe for long-term use?
Vitamin C and glutamine are generally well tolerated long-term, though very high doses of vitamin C above 2 grams daily can cause problems. Taurine is well tolerated short-term in healthy adults, but long-term safety data is less certain — if you plan to use it regularly, discuss that with your doctor.
Will this affect my thyroid medication?
Yes — vitamin C can increase how much levothyroxine (Synthroid and others) your body absorbs, which may raise your thyroid hormone levels. If you take thyroid medication, check with your doctor or pharmacist before starting this product; you may need a dose adjustment.
What are the three BCAAs in this product used for?
The three branched-chain amino acids — L-Leucine, L-Isoleucine, and L-Valine — are amino acids involved in muscle protein synthesis and recovery. We don't hold effectiveness data for them specifically, but they're commonly used by athletes and people focused on muscle performance.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Clean BCAAs Watermelon label
Sources

Sources & How We Checked

Clean BCAAs Watermelon's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 83 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin C 51 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Back DJ, Breckenridge AM, MacIver M, et al. Interaction of ethinyloestradiol with ascorbic acid in man. Br Med J (Clin Res Ed) 1981;282:1516.
  3. Morris JC, Beeley L, Ballantine N. Interaction of ethinyloestradiol with ascorbic acid in man [letter]. Br Med J (Clin Res Ed) 1981;283:503.
  4. Labriola D, Livingston R. Possible interactions between dietary antioxidants and chemotherapy. Oncology 1999;13:1003-8.
  5. Dwyer JH, Merz NB, Shirocre AM, et al. Progression of early atherosclerosis and intake of vitamin C and vitamin E from supplements and food. The Los Angeles Atherosclerosis Study. 41st Annual Conference on Cardiovascular Disease Epidemiology and Prevent
  6. Levine M, Rumsey SC, Daruwala R, et al. Criteria and recommendations for vitamin C intake. JAMA 1999;281:1415-23. PubMed
  7. Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
  8. Segal S, Kaminski S. Drug-nutrient interactions. American Druggist 1996 Jul;42-8.
  9. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. Washington, DC: National Academy Press, 2000. Available at: http://www.nap.edu/books/0309069351/html/.
  10. Houston JB, Levy G. Drug biotransformation interactions in man VI: Acetaminophen and ascorbic acid. J Pharm Sci 1976;65:1218-21. PubMed
  11. Brown BG, Zhao XQ, Chait A, et al. Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease. N Engl J Med 2001;345:1583-93. DOI
  12. Rosenthal G. Interaction of ascorbic acid and warfarin. JAMA 1971;215:1671. DOI
  13. Hume R, Johnstone JM, Weyers E. Interaction of ascorbic acid and warfarin. JAMA 1972;219:1479. DOI
  14. Smith EC, Skalski RJ, Johnson GC, Rossi GV. Interaction of ascorbic acid and warfarin. JAMA 1972;221:1166. DOI
  15. Traxer O, Huet B, Poindexter J, et al. Effect of ascorbic acid consumption on urinary stone risk factors. J Urol 2003;170:397-401.. PubMed
  16. Domingo JL, Gomez M, Llobet JM, Richart C. Effect of ascorbic acid on gastrointestinal aluminum absorption (letter). Lancet 1991;338:1467.
  17. Domingo JL, Gomez M, Llobet JM, Corbella J. Influence of some dietary constituents on aluminum absorption and retention in rats. Kidney Int 1991;39:598-601. PubMed
  18. Partridge NA, Regnier FE, White JL, Hem SL. Influence of dietary constituents on intestinal absorption of aluminum. Kidney Int 1989;35:1413-7. PubMed
  19. Mc Leod DC, Nahata MC. Inefficacy of ascorbic acid as a urinary acidifier (letter). N Engl J Med 1977;296:1413. DOI
  20. Hansten PD, Hayton WL. Effect of antacid and ascorbic acid on serum salicylate concentration. J Clin Pharmacol 1980;20:326-31. PubMed
  21. Dysken MW, Cumming RJ, Channon RA, Davis JM. Drug interaction between ascorbic acid and fluphenazine. JAMA 1979;241:2008. DOI
  22. Vihtamaki T, Parantainen J, Koivisto AM, et al. Oral ascorbic acid increases plasma oestradiol during postmenopausal hormone replacement therapy. Maturitas 2002;42:129-35. PubMed
  23. Slain D, Amsden JR, Khakoo RA, et al. Effect of high-dose vitamin C on the steady-state pharmacokinetics of the protease inhibitor indinavir in healthy volunteers. Pharmacotherapy 2005;25:165-70. PubMed
  24. Cheung MC, Zhao XQ, Chait A, et al. Antioxidant supplements block the response of HDL to simvastatin-niacin therapy in patients with coronary artery disease and low HDL. Arterioscler Thromb Vasc Biol 2001;21:1320-6. PubMed
  25. Feetam CL, Leach RH, Meynell MJ. Lack of a clinically important interaction between warfarin and ascorbic acid. Toxicol Appl Pharmacol 1975;31:544-7. PubMed
  26. Weintraub M, Griner PF. Warfarin and ascorbic acid: lack of evidence for a drug interaction. Toxicol Appl Pharmacol 1974;28:53-6. PubMed
  27. Lee DH, Folsom AR, Harnack L, et al. Does supplemental vitamin C increase cardiovascular disease risk in women with diabetes? Am J Clin Nutr 2004;80:1194-200. PubMed
  28. Taylor EN, Stampfer MJ, Curhan GC. Dietary factors and the risk of incident kidney stones in men: new insights after 14 years of follow-up. J Am Soc Nephrol 2004;15:3225-32. PubMed
  29. Ward NC, Hodgson JM, Croft KD, et al. The combination of vitamin C and grape-seed polyphenols increases blood pressure: a randomized, double-blind, placebo-controlled trial. J Hypertens 2005;23:427-34.. PubMed
  30. Prasad KN. Rationale for using high-dose multiple dietary antioxidants as an adjunct to radiation therapy and chemotherapy. J Nutr 2004;134:3182S-3S. PubMed
  31. Conklin KA. Cancer chemotherapy and antioxidants. J Nutr 2004;134:3201S-3204S. PubMed
  32. Fairweather-Tait S, Hickson K, McGaw B, et al. Orange juice enhances aluminium absorption from antacid preparation. Eur J Clin Nutr. 1994;48(1):71-3.
  33. Gruenwald, J., Graubaum, H. J., Busch, R., and Bentley, C. Safety and tolerance of ester-C compared with regular ascorbic acid. Adv.Ther. 2006;23(1):171-178.
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Glutamine 11 references
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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