CO-Q-Omega Ingredients & Drug Interactions
What is this page for?
First and foremost: checking CO-Q-Omega against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
CO-Q-Omega is a dietary supplement by Purity Products with 2 active ingredients. Its ingredients are commonly taken for brain and cognitive health, eye and vision health, fetal and infant development.Based on those ingredients, 399 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Omega-3 Fatty Acids, CoQ10. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against CO-Q-Omega by Purity Products
Ask about any prescription or over-the-counter medication and we check it for interactions with CO-Q-Omega by Purity Products — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of CO-Q-Omega by Purity Products
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
CO-Q-Omega contains 5 active ingredients. The main components are omega-3 fatty acids — specifically eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), sourced from concentrated fish oil — plus CoQ10 (coenzyme Q10), a compound your cells use for energy production.
The softgel capsule also contains a proprietary system called LemonLock Freshness System to help preserve the product.
Does it work?
Strong evidence
CoQ10 is likely effective for treating CoQ10 deficiency and possibly effective for fibromyalgia, migraine headache, congestive heart failure, and diabetic neuropathy. Evidence for the omega-3 fatty acids in this product is not established in the data we hold, so we can't speak to their effectiveness here.
How safe is it?
Well-documented data
CoQ10 is generally well tolerated when taken as directed. The most common side effects are gastrointestinal — appetite loss, diarrhea, heartburn, nausea, and vomiting — though these occur in less than 1% of users.
Headache, dizziness, and insomnia have been reported occasionally. A very small number of people have reported skin itching or allergic rash.
There isn't enough safety data on CoQ10 in pregnancy, so the safety data advises against use unless your doctor says it's okay. Safety during breastfeeding hasn't been well studied — talk with your doctor before taking this product if you're breastfeeding.
Meds to double-check
Moderate interaction found
If you take any of these, check with your pharmacist before starting: chemotherapy drugs like cyclophosphamide (alkylating agents), warfarin or other blood thinners, and blood pressure medications. CoQ10 may reduce how well chemotherapy works and may interfere with warfarin's effectiveness.
The bottom line
Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
CO-Q-Omega is a reasonable choice if you're looking to support CoQ10 levels or are interested in omega-3 supplementation, but it's important to check with your pharmacist first if you take warfarin, chemotherapy drugs, or blood pressure medications. If you're pregnant or breastfeeding, ask your doctor before starting.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 22, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about CO-Q-Omega, straight from the product label.
| Brand | Purity Products |
|---|---|
| Net contents | 60 Softgel(s) |
| Market status | On market |
| Date entered into DSLD | Jan 22, 2021 |
| DSLD ID | 243505 |
| Product type | Other Combinations |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for CO-Q-Omega by Purity Products, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 20 Calorie(s) | -- |
| Omega-3 Fatty Acids | 1280 mg | -- |
| Eicosapentaenoic Acid | 640 mg | -- |
| Docosahexaenoic Acid | 420 mg | -- |
| Cholesterol | 5 mg | 2% |
| Total Fat | 2 Gram(s) | 3% |
| Polyunsaturated Fat | 1.5 Gram(s) | -- |
| CoQ10 | 50 mg | -- |
| Other Omega-3 Fatty Acids | 220 mg | -- |
Other ingredients: highly refined and concentrated Omega-3 Fish Oil, Capsule Shell, Beeswax, Coenzyme Q10, Proprietary LemonLock Freshness System
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Intelligent nutritional solutions
Premium grade supplements Since 1993
Formula
Ultra-pure fish oil 640mg EPA 420mg DHA 50mg Coenzyme Q10
Formulation
Promotes heart, joint & brain health Featuring LemonLock freshness system
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Suggested Use: As a dietary supplement, adults take 2 softgels daily. For daily use.
Precautions
Contains fish (anchovy, sardines, mackerel) and soy.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
CO-Q-Omega by Purity Products label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in CO-Q-Omega by Purity Products
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Softgel(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Omega-3 Fatty Acids
Interacts with375 drugs
DHA is an omega-3 fatty acid found in fatty fish and algae that is a building block for the brain, nervous system, and eyes. It is widely used and gen...
Omega-3 Fatty Acids monograph & interactions- › Eicosapentaenoic Acid
- › Docosahexaenoic Acid
- › Other Omega-3 Fatty Acids
CoQ10
Interacts with198 drugs
CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated...
CoQ10 monograph & interactionsOther (inactive) ingredients: Highly refined and concentrated Omega-3 Fish Oil, Capsule Shell, Beeswax, Coenzyme Q10, Proprietary LemonLock Freshness System. These complete the product’s ingredient list but are not active constituents.
CO-Q-Omega by Purity Products Drug Interactions
HelloPharmacist Interaction Report
CO-Q-Omega by Purity Products contains CoQ10, which has documented interactions with certain medications.
The most serious concern is with alkylating chemotherapy drugs (like cyclophosphamide) — CoQ10's antioxidant effects may theoretically reduce how well these cancer medications work by protecting tumor cells from the oxidative stress these drugs rely on.
Read the full breakdown — every affected drug type, severity by severity
CoQ10 also interacts with warfarin (a blood thinner). It's chemically similar to vitamin K and may reduce warfarin's effectiveness; a small number of cases of decreased warfarin efficacy linked to CoQ10 have been reported.
Additionally, CoQ10 may have minor additive effects with blood pressure medications — some studies show it can lower blood pressure on its own, though results have been mixed.
We could not check the omega-3 fatty acids in this product (eicosapentaenoic acid, docosahexaenoic acid, polyunsaturated fat, and other omega-3s) because we don't hold interaction data for them. Altogether, these interactions span 198 individual medications.
Use the medication checker on this page to look up your exact drugs before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against CO-Q-Omega?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in CO-Q-Omega interact with 399 drugs. Click any drug to see the details.
2 of the 2 ingredients in CO-Q-Omega interact with drugs. Each result below shows which ingredient is responsible. Omega-3 Fatty Acids CoQ10
AbciximabReoPro
How Abciximab interacts with CO-Q-Omega — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Omega-3 Fatty Acids + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with CO-Q-Omega — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Omega-3 Fatty Acids + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with CO-Q-Omega — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
Read the full Omega-3 Fatty Acids + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with CO-Q-Omega — through 2 ingredients. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Read the full Omega-3 Fatty Acids + Acebutolol interactionCoq10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coq10 + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with CO-Q-Omega — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Omega-3 Fatty Acids + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with CO-Q-Omega — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Omega-3 Fatty Acids + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with CO-Q-Omega — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Omega-3 Fatty Acids + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with CO-Q-Omega — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Omega-3 Fatty Acids + Acetaminophen, Ibuprofen interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with CO-Q-Omega — through 2 ingredients. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Read the full Omega-3 Fatty Acids + Acetazolamide interactionCoq10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coq10 + Acetazolamide interactionAcetohexamideDymelor
How Acetohexamide interacts with CO-Q-Omega — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
Read the full Omega-3 Fatty Acids + Acetohexamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with CO-Q-Omega — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Omega-3 Fatty Acids + Acetylsalicylic Acid interactionAlbiglutideTanzeum
How Albiglutide interacts with CO-Q-Omega — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
Read the full Omega-3 Fatty Acids + Albiglutide interactionAliskirenTekturna
How Aliskiren interacts with CO-Q-Omega — through 2 ingredients. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Read the full Omega-3 Fatty Acids + Aliskiren interactionCoq10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coq10 + Aliskiren interactionAlogliptinNesina
How Alogliptin interacts with CO-Q-Omega — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
Read the full Omega-3 Fatty Acids + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with CO-Q-Omega — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
Read the full Omega-3 Fatty Acids + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with CO-Q-Omega — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
Read the full Omega-3 Fatty Acids + Alogliptin, Pioglitazone interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with CO-Q-Omega — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Omega-3 Fatty Acids + Alteplase, Tpa interactionAltretamineHexalen
How Altretamine interacts with CO-Q-Omega — through 1 ingredient. Tap an ingredient for the detail:
Coq10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coq10 + Altretamine interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with CO-Q-Omega — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Omega-3 Fatty Acids + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with CO-Q-Omega — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Omega-3 Fatty Acids + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with CO-Q-Omega — through 2 ingredients. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Read the full Omega-3 Fatty Acids + Ambrisentan interactionCoq10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coq10 + Ambrisentan interactionAmilorideAmilamont, Midamor
How Amiloride interacts with CO-Q-Omega — through 2 ingredients. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Read the full Omega-3 Fatty Acids + Amiloride interactionCoq10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coq10 + Amiloride interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with CO-Q-Omega — through 2 ingredients. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Read the full Omega-3 Fatty Acids + Amiloride, Hydrochlorothiazide interactionCoq10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coq10 + Amiloride, Hydrochlorothiazide interactionAmlodipineNorliqva
How Amlodipine interacts with CO-Q-Omega — through 2 ingredients. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Read the full Omega-3 Fatty Acids + Amlodipine interactionCoq10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coq10 + Amlodipine interactionAmlodipine BenzoateKaterzia
How Amlodipine Benzoate interacts with CO-Q-Omega — through 2 ingredients. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Read the full Omega-3 Fatty Acids + Amlodipine Benzoate interactionCoq10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coq10 + Amlodipine Benzoate interactionAmlodipine BesilateIstin
How Amlodipine Besilate interacts with CO-Q-Omega — through 2 ingredients. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Read the full Omega-3 Fatty Acids + Amlodipine Besilate interactionCoq10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coq10 + Amlodipine Besilate interactionAmlodipine BesylateNorvasc
How Amlodipine Besylate interacts with CO-Q-Omega — through 2 ingredients. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Read the full Omega-3 Fatty Acids + Amlodipine Besylate interactionCoq10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coq10 + Amlodipine Besylate interactionAmlodipine Besylate, BenazeprilLotrel
How Amlodipine Besylate, Benazepril interacts with CO-Q-Omega — through 2 ingredients. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Read the full Omega-3 Fatty Acids + Amlodipine Besylate, Benazepril interactionCoq10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coq10 + Amlodipine Besylate, Benazepril interactionAmlodipine, CelecoxibConsensi
How Amlodipine, Celecoxib interacts with CO-Q-Omega — through 2 ingredients. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Read the full Omega-3 Fatty Acids + Amlodipine, Celecoxib interactionCoq10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coq10 + Amlodipine, Celecoxib interactionAmmonium ChlorideAmmonium Chloride
How Ammonium Chloride interacts with CO-Q-Omega — through 2 ingredients. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Read the full Omega-3 Fatty Acids + Ammonium Chloride interactionCoq10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coq10 + Ammonium Chloride interactionEach ingredient & the kinds of drugs it affects
For each ingredient in CO-Q-Omega with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Omega-3 Fatty Acids
Anticoagulant/Antiplatelet Drugs
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Although some clinical evidence suggests that DHA might reduce collagen-stimulated platelet aggregation and thromboxane release, most clinical evidence suggests that DHA alone does not affect blood clotting. However, theoretically, when given in combination with EPA as fish oil, concomitant use with anticoagulant or antiplatelet drugs (including aspirin) might increase risk of bleeding.
Antidiabetes Drugs
Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
In people with type 2 diabetes, including those taking oral hypoglycemic medications, DHA seems to increase fasting blood glucose levels.
Antihypertensive Drugs
Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Fish oils containing DHA can lower blood pressure and might have additive effects in patients treated with antihypertensives; use with caution.
CoQ10
Alkylating Agents
Coenzyme Q10 has antioxidant effects. Theoretically, this may reduce the activity of chemotherapy drugs that generate free radicals.
Theoretically, antioxidants such as coenzyme Q10 might protect tumor cells from chemotherapeutic agents that work by inducing oxidative stress, such as alkylating agents (e.g., cyclophosphamide) and radiation therapy. The clinical importance of this interaction is unknown.
Warfarin (Coumadin)
Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Concomitant use of coenzyme Q10 and warfarin might reduce the anticoagulant effects of warfarin. Four cases of decreased warfarin efficacy thought to be due to coenzyme Q10 have been reported. However, there is some preliminary clinical research that suggests coenzyme Q10 might not significantly decrease the effects of warfarin in patients who have a stable INR.
Antihypertensive Drugs
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Some clinical research shows that coenzyme Q10 can significantly lower blood pressure, although other studies have shown conflicting results.
Brand information
Manufacturer and brand details for CO-Q-Omega, from the product label.
CO-Q-Omega by Purity Products: Common Questions
Does CO-Q-Omega by Purity Products interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this if I'm on warfarin?
What side effects might I notice?
Is this product safe during pregnancy?
Can I take this while breastfeeding?
What is CoQ10 supposed to do?
What's in the capsule itself?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if CO-Q-Omega is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind CO-Q-Omega’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Docosahexaenoic Acid (dha)
Interacts with 375 drugsDHA is an omega-3 fatty acid found in fatty fish and algae that is a building block for the brain, nervous system, and eyes. It is widely used and generally well tolerated, with the stronges...
Read the full Docosahexaenoic Acid (dha) monograph → Herb & supplement monographCoenzyme Q10
Interacts with 198 drugsCoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated and is most studied for heart condition...
Read the full Coenzyme Q10 monograph →Sources & How We Checked
CO-Q-Omega's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 89 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Docosahexaenoic Acid (dha) 49 references
- Akedo I, Ishikawa H, Nakamura T, et al. Three cases with familial adenomatous polyposis diagnosed as having malignant lesions in the course of a long-term trial using docosahexanoic acid (DHA)-concentrated fish oil capsules (abstract). Jpn J Clin Oncol PubMed
- Prisco D, Paniccia R, Bandinelli B, et al. Effect of medium-term supplementation with a moderate dose of n-3 polyunsaturated fatty acids on blood pressure in mild hypertensive patients. Thromb Res 1998;1:105-12.
- Grimsgaard S, Bonaa KH, Hansen JB, Nordoy A. Highly purified eicosapentaenoic acid and docosahexaenoic acid in humans have similar triacylglycerol-lowering effects but divergent effects on serum fatty acids. Am J Clin Nutr 1997;66:649-59.
- Toft I, Bonaa KH, Ingebretsen OC, et al. Effects of n-3 polyunsaturated fatty acids on glucose homeostasis and blood pressure in essential hypertension. A randomized, controlled trial. Ann Intern Med 1995;123:911-8.
- Sacks FM, Hebert P, Appel LJ, et al. Short report: the effect of fish oil on blood pressure and high-density lipoprotein-cholesterol levels in phase I of the trials of hypertension prevention. J Hypertens 1994;12:209-13.
- Vandongen R, Mori TA, Burke V, et al. Effects on blood pressure of omega 3 fats in subjects at increased risk of cardiovascular disease. Hypertension 1993;22:371-9. PubMed
- FDA. Center for Food Safety and Applied Nutrition. Letter regarding dietary supplement health claim for omega-3 fatty acids and coronary heart disease. Available at: http://www.fda.gov/ohrms/dockets/dockets/95s0316/95s-0316-Rpt0272-38-Appendix-D-Reference
- Pedersen HS, Mulvad G, Seidelin KN, et al. N-3 fatty acids as a risk factor for haemorrhagic stroke. Lancet 1999;353:812-3. PubMed
- Ito Y, Suzuki K, Imai H, et al. Effects of polyunsaturated fatty acids on atrophic gastritis in a Japanese population. Cancer Lett 2001;163:171-8. PubMed
- Kris-Ehterton PM, Harris WS, Appel LJ, et al. Fish consumption, fish oil, omega-3 fatty acids, and cardiovascular disease. Circulation 2002;106:2747-57. PubMed
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See these in context on the Docosahexaenoic Acid (dha) monograph →
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