Interactions on record — worth a quick check against your medications. Based on 3 of 4 ingredients. Check your meds →
Dietary supplement

Complete Feminine Balance Ingredients & Drug Interactions

by AZO

Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Complete Feminine Balance is a dietary supplement by AZO with 4 active ingredients. Its ingredients are commonly taken for vaginal health support, preventing recurrent bacterial vaginosis, reducing recurrent urinary tract infections.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lactobacillus crispatus LBV 88, Lactobacillus gasseri LBV 150N, Lactobacillus jensenii LBV 116. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Complete Feminine Balance by AZO

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 4 active ingredients.
  • “Intelliflora Blend” is a proprietary blend — the label gives one combined amount (150 mg) without saying how much of each component you get.

Complete Feminine Balance contains four Lactobacillus strains — crispatus, rhamnosus, gasseri, and jensenii — all live, active cultures meant to support vaginal flora balance. These are probiotics (beneficial bacteria) formulated specifically for women's health.

The product also includes fructooligosaccharides (a prebiotic fiber that feeds beneficial bacteria) and standard inactive ingredients like cellulose and magnesium stearate for capsule structure.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: maintain vaginal health and pH balance.
  • We looked for evidence on: Bacterial vaginosis, Urinary tract infections (UTIs), yeast infections, vaginal microbiome imbalance.
  • The strongest evidence on file: Lactobacillus Crispatus is rated "Possibly Effective" for Bacterial vaginosis (Natural Medicines).
  • Also on file: Lactobacillus Crispatus is rated "Insufficient Reliable Evidence To Rate" for Urinary tract infections (UTIs).
  • Also on file: Lactobacillus Gasseri is rated "Insufficient Reliable Evidence To Rate" for Bacterial vaginosis.

The evidence for these Lactobacillus strains is limited and mixed. Lactobacillus crispatus is possibly effective for bacterial vaginosis, but the data for the other strains in this product — including their use for urinary tract infections, preterm labor, or general vaginal health — is insufficient to rate.

We don't have effectiveness ratings on file for Lactobacillus jensenii as a standalone ingredient. Talk with your doctor about whether this product is the right choice for your specific concern.

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

These Lactobacillus strains are generally well tolerated in healthy adults, though the overall safety evidence for probiotic supplements is limited. Rarely, people have reported nausea, gas, bloating, and in very uncommon cases, swelling of the tongue.

Since these are live organisms, there is a theoretical concern that in rare cases they might cause infection in certain patients — particularly those who are immunocompromised — though this is uncommon. Safety data during pregnancy and breastfeeding is not well established.

If you're pregnant or breastfeeding, talk with your doctor before starting this product, as the data we hold doesn't provide clear guidance either way.

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Lactobacillus Crispatus, Lactobacillus Gasseri, Lactobacillus Jensenii.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take antibiotic drugs, separate them from this product — antibiotics can kill the live bacteria in these capsules and reduce its effectiveness. Ask your pharmacist for the best timing.

No other major medication interactions are documented for the ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

AZO Complete Feminine Balance is a probiotic blend designed for vaginal health, with the strongest evidence for bacterial vaginosis. If you take antibiotics, you'll need to time this supplement carefully so the antibiotic doesn't kill the live cultures.

Before you start, especially if you're pregnant, breastfeeding, or have a compromised immune system, check in with your doctor or pharmacist to make sure it's right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Complete Feminine Balance, straight from the product label.

Brand AZO
Barcode (UPC) 787651760186
Net contents 60 Once daily capsule(s)
Market status On market
Date entered into DSLD Mar 25, 2021
DSLD ID 242644
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult Female (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Complete Feminine Balance by AZO, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
787651760186
IngredientAmount% DV
Calories0 Calorie(s)--
Total Carbohydrates0 Gram(s)--
Added Sugars0 Gram(s)--
Total Sugars0 Gram(s)--
Intelliflora Blend150 mg--
Lactobacillus crispatus LBV 880 NP--
Lactobacillus rhamnosus LBV 960 NP--
Lactobacillus gasseri LBV 150N0 NP--
Lactobacillus jensenii LBV 1160 NP--

Other ingredients: Microcrystalline Cellulose, Hydroxypropyl Methylcellulose, Fructooligosaccharides, Magnesium Stearate, Titanium Dioxide, Caramel

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

A solution as unique as your feminine health needs. Maintaining feminine health is quite the balancing act. But let’s be honest: issues can happen! Stress, your period, sex, hygiene, and even certain medications can disrupt your vaginal environment and throw off pH, leaving you feeling anything but balanced.

To the rescue: AZO Complete Feminine Balance It works differently because it contains Intelliflora, the only clinically proven blend with the 4 Lactobacilli species most commonly found in healthy women. Intelliflora helps to restore the natural balance of good bacteria and yeast to maintain vaginal health.

With the power of Intelliflora 4 unique strains

Beneficial for all women. Safe for pregnant women. Designed to help keep women healthy

Clinically proven to maintain feminine health

5 billion active cultures

Formulation

Proven to help support natural defenses to protect your vaginal health Works naturally with a woman's body to help maintain a healthy pH Clinically shown to work in 7 days Because when you have occasional feminine issues, you don’t need a probiotic designed for gut health, you need something formulated specifically for vaginal health. Trust AZO Complete Feminine Balance, a once daily oral capsule proven to maintain feminine health.

Helps support natural defenses to protect vaginal health Daily probiotic Restores the natural balance of good bacteria & yeast Helps maintain a healthy pH

Country of origin: Italy.

Contains none of the following: artificial dyes, preservatives, dairy, lactose, milk, gluten, yeast, soy or gelatin. Sugar free.

General Statements

Results demonstrated in clinical studies using the probiotic blend in this product.

Own your day AZO Values: We believe in open, honest conversations about women’s health We believe in helping you take charge of your health We believe in helping you live your life to the fullest We believe in delivering the best urinary, vaginal, and bladder health products available We believe in helping you, Own your Day.

2 month supply!

Not a reduced calorie food.

Precautions

For questions, concerns or to report an adverse event, call (800)722-3476. www.azoproducts.com

Caution: As with any dietary supplement, please inform your healthcare professional before taking.

Keep out of reach of children.

Tamper Evident: Do not use this product if safety seal bearing “sealed for your protection” under cap is missing.

Brand IP Statement(s)

AZO Complete Feminine Balance, Own your Day and Intelliflora are trademarks of DSM.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Take orally. One (1) capsule daily. May be taken at any time of day, with or without food

Storage

Storage Instructions: Store in a cool, dry place away from direct sunlight.

See for yourself

Complete Feminine Balance by AZO label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Complete Feminine Balance by AZO

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Intelliflora Blend

150 mg per serving

Other (inactive) ingredients: Microcrystalline Cellulose, Hydroxypropyl Methylcellulose, Fructooligosaccharides, Magnesium Stearate, Titanium Dioxide, Caramel. These complete the product’s ingredient list but are not active constituents.

Interaction report

Complete Feminine Balance by AZO Drug Interactions

Want to check YOUR meds against Complete Feminine Balance?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
182Drugs
182 Moderate

Each ingredient & the kinds of drugs it affects

For each ingredient in Complete Feminine Balance with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Lactobacillus crispatus LBV 881 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus crispatus with antibiotic drugs might decrease the effectiveness of L. crispatus.
Lactobacillus crispatus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. crispatus preparations by at least two hours.

Likelihood Probable Evidence D

Lactobacillus gasseri LBV 150N1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus gasseri with antibiotic drugs might decrease the effectiveness of L. gasseri.
Lactobacillus gasseri preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. gasseri preparations by at least two hours.

Likelihood Probable Evidence D

Lactobacillus jensenii LBV 1161 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus jensenii with antibiotic drugs might decrease the effectiveness of L. jensenii.
Lactobacillus jensenii preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. jensenii preparations by at least two hours.

Likelihood Probable Evidence D
The maker

Brand information

Manufacturer and brand details for Complete Feminine Balance, from the product label.

AZO

See all AZO products
Name
i-Health, Inc.
Street Address
55 Sebethe Drive
City
Cromwell
State
CT
ZipCode
06416
Phone Number
800-722-3476
Web Address
www.azoproducts.com
Pharmacist Counseling Corner

Complete Feminine Balance by AZO: Common Questions

Does Complete Feminine Balance by AZO interact with any medications?
Yes. Based on its ingredients, Complete Feminine Balance has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Complete Feminine Balance contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this with antibiotics?
You can, but timing matters. Antibiotics might kill the live bacteria in these capsules. Space your antibiotic and this supplement apart — your pharmacist can tell you the best gap between doses.
What are these Lactobacillus strains for?
They're probiotics meant to support your vaginal flora balance. Lactobacillus crispatus is possibly effective for bacterial vaginosis; the evidence for the others and for other conditions is still being studied.
Is it safe to take while breastfeeding?
There isn't enough safety data yet to say for certain. Talk with your doctor before taking this product while breastfeeding.
Are there any side effects?
They're rare, but nausea, gas, and bloating have occasionally been reported. In very uncommon cases, people have had swelling of the tongue. Stop and call your doctor if anything unusual happens.
Does this product have fillers?
Yes, it contains inactive ingredients like microcrystalline cellulose, magnesium stearate, and caramel for structure and appearance. These are standard in capsule supplements.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Complete Feminine Balance is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Complete Feminine Balance label
Sources

Sources & How We Checked

Complete Feminine Balance's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 27 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lactobacillus Crispatus 9 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  3. Ranchal P, Gupta R, Goldberg R, A Lobo S, Pascual A, El Khoury MY. Penicillin-sensitive Lactobacillus jensenii bacteremia. Am J Ther 2021;28(2):e250-e252. PubMed
  4. Grazioli-Gauthier L, Rigamonti E, Leo LA, Martinetti Lucchini G, Lo Priore E, Bernasconi E. Lactobacillus jensenii mitral valve endocarditis: Case report, literature review and new perspectives. IDCases 2022;27:e01401. PubMed
  5. Toprak NU, Bozan T, Yilmaz S, Buyukbayrak EE, Tigen ET. Polymicrobial bacteremia due to Lactobacillus jensenii and Veillonella montpellierensis in a pregnant patient; case report and review of literature. Anaerobe 2022;75:102576. PubMed
  6. Chazan B, Raz R, Shental Y, Sprecher H, Colodner R. Bacteremia and pyelonephritis caused by Lactobacillus jensenii in a patient with urolithiasis. Isr Med Assoc J 2008;10(2):164-5.
  7. DI Pierro F, Criscuolo AA, Dei Giudici A, et al. Oral administration of Lactobacillus crispatus M247 to papillomavirus-infected women: results of a preliminary, uncontrolled, open trial. Minerva Obstet Gynecol 2021;73(5):621-631. PubMed
  8. DE Leo V, Lazzeri E, Governini L, et al. Vaginal colonization of women after oral administration of Lactobacillus crispatus strain NTCVAG04 from the human microbiota. Minerva Obstet Gynecol 2022. PubMed
  9. Dellino M, Cascardi E, Laganà AS, et al. Lactobacillus crispatus M247 oral administration: Is it really an effective strategy in the management of papillomavirus-infected women?. Infect Agent Cancer 2022;17(1):53. PubMed

See these in context on the Lactobacillus Crispatus monograph →

Lactobacillus Gasseri 12 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Ramachandran L, Dontaraju VS, Patel K. Lactobacillus-associated spontaneous bacterial peritonitis in a liver cirrhosis patient on probiotics. Cureus. 2020;12(12):e11896. PubMed
  3. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  4. Ranchal P, Gupta R, Goldberg R, A Lobo S, Pascual A, El Khoury MY. Penicillin-sensitive Lactobacillus jensenii bacteremia. Am J Ther 2021;28(2):e250-e252. PubMed
  5. Grazioli-Gauthier L, Rigamonti E, Leo LA, Martinetti Lucchini G, Lo Priore E, Bernasconi E. Lactobacillus jensenii mitral valve endocarditis: Case report, literature review and new perspectives. IDCases 2022;27:e01401. PubMed
  6. Toprak NU, Bozan T, Yilmaz S, Buyukbayrak EE, Tigen ET. Polymicrobial bacteremia due to Lactobacillus jensenii and Veillonella montpellierensis in a pregnant patient; case report and review of literature. Anaerobe 2022;75:102576. PubMed
  7. Chazan B, Raz R, Shental Y, Sprecher H, Colodner R. Bacteremia and pyelonephritis caused by Lactobacillus jensenii in a patient with urolithiasis. Isr Med Assoc J 2008;10(2):164-5.
  8. Ramos-Coria D, Canto-Losa J, Carrillo-Vázquez D, Carbajal-Morelos L, Estrada-León R, Corona-Rodarte E. Lactobacillus gasseri liver abscess and bacteremia: a case report. BMC Infect Dis 2021;21(1):518. PubMed
  9. Elikowski W, Malek-Elikowska M, Lisiecka M, Bodora A, Wisniewska K, Oko-Sarnowska Z. Lactobacillus gasseri endocarditis on the aortic valve bioprosthesis - a case report. Pol Merkur Lekarski 2017;43(257):220-223.
  10. Esquibel A, Dababneh AS, Palraj BR. Lactobacillus gasseri causing bilateral empyema. Case Rep Infect Dis 2017;2017:4895619.
  11. Tleyjeh IM, Routh J, Qutub MO, Lischer G, Liang KV, Baddour LM. Lactobacillus gasseri causing Fournier's gangrene. Scand J Infect Dis 2004;36(6-7):501-3. PubMed
  12. Dickgiesser U, Weiss N, Fritsche D. Lactobacillus gasseri as the cause of septic urinary infection. Infection 1984;12(1):14-6. PubMed

See these in context on the Lactobacillus Gasseri monograph →

Lactobacillus Jensenii 6 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  3. Ranchal P, Gupta R, Goldberg R, A Lobo S, Pascual A, El Khoury MY. Penicillin-sensitive Lactobacillus jensenii bacteremia. Am J Ther 2021;28(2):e250-e252. PubMed
  4. Grazioli-Gauthier L, Rigamonti E, Leo LA, Martinetti Lucchini G, Lo Priore E, Bernasconi E. Lactobacillus jensenii mitral valve endocarditis: Case report, literature review and new perspectives. IDCases 2022;27:e01401. PubMed
  5. Toprak NU, Bozan T, Yilmaz S, Buyukbayrak EE, Tigen ET. Polymicrobial bacteremia due to Lactobacillus jensenii and Veillonella montpellierensis in a pregnant patient; case report and review of literature. Anaerobe 2022;75:102576. PubMed
  6. Chazan B, Raz R, Shental Y, Sprecher H, Colodner R. Bacteremia and pyelonephritis caused by Lactobacillus jensenii in a patient with urolithiasis. Isr Med Assoc J 2008;10(2):164-5.

See these in context on the Lactobacillus Jensenii monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring