CoQ10 Ingredients & Drug Interactions
What is this page for?
First and foremost: checking CoQ10 against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
CoQ10 is a dietary supplement by aSquared Nutrition with 1 active ingredient. Its ingredients are commonly taken for heart health, statin-related muscle aches, migraine prevention.Based on those ingredients, 198 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Coenzyme Q-10, Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against CoQ10 by aSquared Nutrition
Ask about any prescription or over-the-counter medication and we check it for interactions with CoQ10 by aSquared Nutrition — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of CoQ10 by aSquared Nutrition
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: Coenzyme Q-10 (CoQ10), a naturally occurring compound your body uses to generate energy in cells and protect them from oxidative damage. It comes as a powder in a capsule form.
The inactive ingredients are cellulose and rice flour, which serve as a filler and flow agent.
Does it work?
Strong evidence
CoQ10 is likely effective for replacing CoQ10 when your body is deficient in it. The evidence is possibly effective for fibromyalgia, migraine headaches, congestive heart failure, and diabetic nerve pain — meaning some research supports it, but the data isn't yet strong enough to be certain.
We don't hold effectiveness data for other uses you might be considering.
How safe is it?
Well-documented data
CoQ10 is generally well tolerated in adults when taken as directed. The most common side effects are mild gastrointestinal issues — appetite suppression, diarrhea, heartburn, nausea, and vomiting — occurring in less than 1% of people, and these often improve if you split doses above 100 mg throughout the day.
Headache, dizziness, insomnia, and skin itching have been reported rarely. The facts don't provide enough safety data in pregnancy, so it's best to avoid it unless your doctor advises otherwise.
Safety while breastfeeding hasn't been well studied either — talk with your doctor or pharmacist before using it if you're nursing.
Meds to double-check
Moderate interaction found
Double-check before using if you take warfarin or blood thinners, chemotherapy drugs (especially alkylating agents), or blood pressure medications. The warfarin interaction is the most concerning — it's moderate severity and documented.
If you're on any of these, run them through the interaction checker on this page.
The bottom line
Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.
CoQ10 may help if your body is deficient in it or if you're exploring options for heart health, migraines, or nerve pain — but research on those uses is still developing. If you take warfarin, chemotherapy, or blood pressure medication, check with us first.
Talk to your pharmacist before starting, especially if you're pregnant or breastfeeding.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 11, 2022.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about CoQ10, straight from the product label.
| Brand | aSquared Nutrition |
|---|---|
| Barcode (UPC) | X00132MTIV |
| Net contents | 200 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Apr 11, 2022 |
| DSLD ID | 263855 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Women (not pregnant or lactating) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for CoQ10 by aSquared Nutrition, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Coenzyme Q-10, Powder | 400 mg | -- |
Other ingredients: Cellulose, Rice Flour
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested Use: For adults, take one (1) capsule daily. For best results take with a meal, or as directed by your healthcare professional.
Precautions
Caution: Do not exceed the recommended dose.
Not intended for use by pregnant or nursing women.
Not intended for children under the age of 18.
If you are taking any medications or have a known medical condition, consult your doctor before use.
Discontinue use and consult your doctor if any adverse reactions occur.
Keep out of reach of children.
Do not use if safety seal is damaged or missing.
Seals/Symbols
GMP Good Manufacturing Practice Quality Assured
USA Formulated
General Statements
Please recycle
200 capsules
Storage
Store in a cool, dry place.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Formulation
Vegan friendly
Enhanced absorption Supports heart health & function Promotes energy & stamina Supports healthy brain function
FDA Statement of Identity
Dietary Supplement
Formula
The antioxidant CoQ10 is naturally made in the human body, and is necessary for basic cell function. Maintaining healthy CoQ10 levels supports heart health, promotes energy & stamina, and supports healthy brain function.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
CoQ10 by aSquared Nutrition label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in CoQ10 by aSquared Nutrition
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Vegetable Capsule(s) Dosage formCapsule Servings per container200 Amounts shown are per serving.
Coenzyme Q-10, Powder
Interacts with198 drugs
CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated...
Coenzyme Q-10, Powder monograph & interactionsOther (inactive) ingredients: Cellulose, Rice Flour. These complete the product’s ingredient list but are not active constituents.
CoQ10 by aSquared Nutrition Drug Interactions
HelloPharmacist Interaction Report
CoQ10 by aSquared Nutrition can interact with a few important medication types.
The main concern is warfarin (a blood thinner used to prevent clots), where CoQ10 might reduce how well it works — there are four documented cases of this happening. Because CoQ10 is chemically similar to vitamin K, it may have clot-promoting effects that counteract warfarin's action.
Read the full breakdown — every affected drug type, severity by severity
CoQ10 may also interfere with certain chemotherapy drugs, particularly alkylating agents like cyclophosphamide. Since these drugs kill cancer cells by creating damaging free radicals, CoQ10's antioxidant effect could theoretically shield tumors and reduce the chemotherapy's activity.
This is a theoretical concern, but it's important enough to discuss with your oncologist before starting CoQ10 during cancer treatment.
Lastly, if you take blood pressure medications (antihypertensives), be aware that CoQ10 itself can lower blood pressure in some people, so combined use might lower it more than intended — though research on this is mixed. Altogether, these interactions span 198 individual medications.
Check your exact drugs with the tool below before starting.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against CoQ10?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in CoQ10 interact with 198 drugs. Click any drug to see the details.
1 of the 1 ingredient in CoQ10 interact with drugs. Each result below shows which ingredient is responsible. Coenzyme Q-10, Powder
AltretamineHexalen
How Altretamine interacts with CoQ10 — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10, PowderAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q-10, Powder + Altretamine interactionBendamustineBelrapzo, Treanda, Vivimusta
How Bendamustine interacts with CoQ10 — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10, PowderAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q-10, Powder + Bendamustine interactionBendamustine HydrochlorideBendeka
How Bendamustine Hydrochloride interacts with CoQ10 — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10, PowderAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q-10, Powder + Bendamustine Hydrochloride interactionBusulfanBusulfex, Myleran
How Busulfan interacts with CoQ10 — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10, PowderAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q-10, Powder + Busulfan interactionCarboplatinParaplatin
How Carboplatin interacts with CoQ10 — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10, PowderAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q-10, Powder + Carboplatin interactionCarmustineBiCNU, Gliadel, Gliadel Wafer
How Carmustine interacts with CoQ10 — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10, PowderAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q-10, Powder + Carmustine interactionChlorambucilLeukeran
How Chlorambucil interacts with CoQ10 — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10, PowderAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q-10, Powder + Chlorambucil interactionCisplatinPlatinol-AQ
How Cisplatin interacts with CoQ10 — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10, PowderAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q-10, Powder + Cisplatin interactionCyclophosphamideCytoxan, Neosar
How Cyclophosphamide interacts with CoQ10 — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10, PowderAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q-10, Powder + Cyclophosphamide interactionDacarbazineDTIC-Dome
How Dacarbazine interacts with CoQ10 — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10, PowderAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q-10, Powder + Dacarbazine interactionEstramustine Phosphate SodiumEmcyt
How Estramustine Phosphate Sodium interacts with CoQ10 — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10, PowderAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q-10, Powder + Estramustine Phosphate Sodium interactionIfosfamideIfex
How Ifosfamide interacts with CoQ10 — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10, PowderAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q-10, Powder + Ifosfamide interactionLomustineCeenu
How Lomustine interacts with CoQ10 — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10, PowderAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q-10, Powder + Lomustine interactionLurbinectedinZepzelca
How Lurbinectedin interacts with CoQ10 — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10, PowderAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q-10, Powder + Lurbinectedin interactionMechlorethamine HydrochlorideValchlor
How Mechlorethamine Hydrochloride interacts with CoQ10 — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10, PowderAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q-10, Powder + Mechlorethamine Hydrochloride interactionMelphalanAlkeran, Hepzato
How Melphalan interacts with CoQ10 — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10, PowderAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q-10, Powder + Melphalan interactionMelphalan FlufenamidePepaxto
How Melphalan Flufenamide interacts with CoQ10 — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10, PowderAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q-10, Powder + Melphalan Flufenamide interactionMelphalan HydrochlorideEvomela
How Melphalan Hydrochloride interacts with CoQ10 — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10, PowderAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q-10, Powder + Melphalan Hydrochloride interactionOxaliplatinEloxatin
How Oxaliplatin interacts with CoQ10 — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10, PowderAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q-10, Powder + Oxaliplatin interactionProcarbazineMatulane
How Procarbazine interacts with CoQ10 — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10, PowderAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q-10, Powder + Procarbazine interactionStreptozocinZanosar
How Streptozocin interacts with CoQ10 — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10, PowderAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q-10, Powder + Streptozocin interactionTemozolomideTemodar
How Temozolomide interacts with CoQ10 — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10, PowderAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q-10, Powder + Temozolomide interactionThiotepaTepadina, Thioplex
How Thiotepa interacts with CoQ10 — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10, PowderAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q-10, Powder + Thiotepa interactionTrabectedinYondelis
How Trabectedin interacts with CoQ10 — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10, PowderAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q-10, Powder + Trabectedin interactionWarfarinWarfarin
How Warfarin interacts with CoQ10 — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10, PowderWarfarin (coumadin) Moderate
Interaction Summary
Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Read the full Coenzyme Q-10, Powder + Warfarin interactionWarfarin SodiumCoumadin, Panwarfin, Sofarin
How Warfarin Sodium interacts with CoQ10 — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10, PowderWarfarin (coumadin) Moderate
Interaction Summary
Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Read the full Coenzyme Q-10, Powder + Warfarin Sodium interactionEach ingredient & the kinds of drugs it affects
For each ingredient in CoQ10 with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Coenzyme Q-10, Powder
Alkylating Agents
Coenzyme Q10 has antioxidant effects. Theoretically, this may reduce the activity of chemotherapy drugs that generate free radicals.
Theoretically, antioxidants such as coenzyme Q10 might protect tumor cells from chemotherapeutic agents that work by inducing oxidative stress, such as alkylating agents (e.g., cyclophosphamide) and radiation therapy. The clinical importance of this interaction is unknown.
Warfarin (Coumadin)
Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Concomitant use of coenzyme Q10 and warfarin might reduce the anticoagulant effects of warfarin. Four cases of decreased warfarin efficacy thought to be due to coenzyme Q10 have been reported. However, there is some preliminary clinical research that suggests coenzyme Q10 might not significantly decrease the effects of warfarin in patients who have a stable INR.
Antihypertensive Drugs
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Some clinical research shows that coenzyme Q10 can significantly lower blood pressure, although other studies have shown conflicting results.
Brand information
Manufacturer and brand details for CoQ10, from the product label.
aSquared Nutrition
See all aSquared Nutrition products- Name
- aSquared Brands LLC
- Street Address
- 382 NE 191st Street, #98406
- City
- Miami
- State
- FL
- ZipCode
- 33179
- Phone Number
- Office: 1-800-557-4120
CoQ10 by aSquared Nutrition: Common Questions
Does CoQ10 by aSquared Nutrition interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What exactly is CoQ10 and what does it do in my body?
Will CoQ10 help with my heart health?
Can I take this if I'm pregnant?
What side effects should I watch for?
Is it safe to use with my blood pressure medication?
Can I take CoQ10 while I'm breastfeeding?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if CoQ10 is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind CoQ10’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
CoQ10's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 40 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Coenzyme Q10 40 references
- Kamikawa T, Kobayashi A, Yamashita T, et al. Effects of coenzyme Q10 on exercise tolerance in chronic stable angina pectoris. Am J Cardiol 1985;56:247-51. PubMed
- Langsjoen P, Willis R, Folkers K. Treatment of essential hypertension with coenzyme Q10. Mol Aspects Med 1994;S265-72. PubMed
- Spigset O. Reduced effect of warfarin caused by ubidecarenone. Lancet 1994;334:1372-3. PubMed
- Singh RB, Niaz MA, Rastogi SS, et al. Effect of hydrosoluble coenzyme Q10 on blood pressures and insulin resistance in hypertensive patients with coronary artery disease. J Hum Hypertens 1999;13:203-8. PubMed
- Portakal O, Ozkaya O, Erden Inal M, et al. Coenzyme Q10 concentrations and antioxidant status in tissues of breast cancer patients. Clin Biochem 2000;33:279-84. PubMed
- Lund EL, Quistorff B, Spang-Thomsen M, Kristjansen PE. Effect of radiation therapy on small-cell lung cancer is reduced by ubiquinone intake. Folia Microbiol (Praha) 1998;43:505-6. PubMed
- Langsjoen PH, Langsjoen PH, Folkers K. Long-term efficacy and safety of coenzyme Q10 therapy for idiopathic dilated cardiomyopathy. Am J Cardiol 1990;65:521-3. PubMed
- Heck AM, DeWitt BA, Lukes AL. Potential interactions between alternative therapies and warfarin. Am J Health Syst Pharm 2000;57:1221-7. DOI
- Landbo C, Almdal TP. [Interaction between warfarin and coenzyme Q10]. Ugeskr Laeger 1998;160:3226-7.
- Baggio E, Gandini R, Plauncher AC, et al. Italian multicenter study on the safety and efficacy of coenzyme Q10 as adjunctive therapy in heart failure. CoQ10 Drug Surveillance Investigators. Mol Aspects Med 1994;15 Suppl:S287-94. PubMed
- Burke BE, Neuenschwander R, Olson RD. Randomized, double-blind, placebo-controlled trial of coenzyme Q10 in isolated systolic hypertension. South Med J 2001;94:1112-7. PubMed
- The Huntington Study Group. A randomized, placebo-controlled trial of coenzyme Q10 and remacemide in Huntington's disease. Neurology 2001;57:397-404.
- Hodgson JM, Watts GF, Playford DA, et al. Coenzyme Q10 improves blood pressure and glycaemic control: a controlled trial in subjects with type 2 diabetes. Eur J Clin Nutr 2002;56:1137-42. PubMed
- Singh RB, Neki NS, Kartikey K, et al. Effect of coenzyme Q10 on risk of atherosclerosis in patients with recent myocardial infarction. Mol Cell Biochem 2003;246:75-82. DOI
- Porterfield LM. Why did the response to warfarin change? RN 2000;63:107.
- Sandor PS, Di Clemente L, Coppola G, et al. Efficacy of coenzyme Q10 in migraine prophylaxis: A randomized controlled trial. Neurology 2005;64:713-5. PubMed
- Engelsen J, Nielsen JD, Winther K. Effect of coenzyme Q10 and Ginkgo biloba on warfarin dosage in stable, long-term warfarin treated outpatients. A randomised, double blind, placebo-crossover trial. Thromb Haemost 2002;87:1075-6. DOI
- Berman M, Erman A, Ben-Gal T, et al. Coenzyme Q10 in patients with end-stage heart failure awaiting cardiac transplantation: a randomized, placebo-controlled study. Clin Cardiol 2004;27:295–9. PubMed
- Storch A, Jost WH, Vieregge P, et al. Randomized, double-blind, placebo-controlled trial on symptomatic effects of coenzyme Q10 in Parkinson disease. Arch Neurol 2007;64:938-44. DOI
- Digiesi V, Cantini F, Oradei A, et al. Coenzyme Q10 in essential hypertension. Mol Aspects Med 1994;15 Suppl:s257-63. PubMed
- Yamagami T, Takagi M, Akagami H, et al. Effect of coenzyme Q10 on essential hypertension, a double blind controlled study. In: Folkers KA, Yamamura Y, eds. Biomedical and Clinical Aspects of Coenzyme Q, Vol. 5. Amsterdam: Elsevier Science Publications, 19
- Ho MJ, Bellusci A, Wright JM. Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension (review). Cochrane Database Syst Rev 2009;(4):CD007435. PubMed
- Rosenfeldt, F. L., Haas, S. J., Krum, H., Hadj, A., Ng, K., Leong, J. Y., and Watts, G. F. Coenzyme Q10 in the treatment of hypertension: a meta-analysis of the clinical trials. J Hum.Hypertens. 2007;21(4):297-306. PubMed
- Stamelou, M., Reuss, A., Pilatus, U., Magerkurth, J., Niklowitz, P., Eggert, K. M., Krisp, A., Menke, T., Schade-Brittinger, C., Oertel, W. H., and Hoglinger, G. U. Short-term effects of coenzyme Q10 in progressive supranuclear palsy: a randomized, place DOI
- Keogh A, Fenton S, Leslie C, et al. Randomised double-blind, placebo-controlled trial of coenzyme Q, therapy in class II and III systolic heart failure. Heart Lung Circ. 2003;12:135-41.
- Gane, E. J., Weilert, F., Orr, D. W., Keogh, G. F., Gibson, M., Lockhart, M. M., Frampton, C. M., Taylor, K. M., Smith, R. A., and Murphy, M. P. The mitochondria-targeted anti-oxidant mitoquinone decreases liver damage in a phase II study of hepatitis C
- Lynch, D. R., Perlman, S. L., and Meier, T. A phase 3, double-blind, placebo-controlled trial of idebenone in friedreich ataxia. Arch Neurol. 2010;67(8):941-947. PubMed
- Young, J. M., Florkowski, C. M., Molyneux, S. L., McEwan, R. G., Frampton, C. M., Nicholls, M. G., Scott, R. S., and George, P. M. A randomized, double-blind, placebo-controlled crossover study of coenzyme Q10 therapy in hypertensive patients with the me
- Ishiyama, T., Morita, Y., Toyama, S., Yamagami, T., and Tsukamoto, N. A clinical study of the effect of coenzyme Q on congestive heart failure. Jpn.Heart J 1976;17(1):32-42. PubMed
- Matthews, P. M., Ford, B., Dandurand, R. J., Eidelman, D. H., O'Connor, D., Sherwin, A., Karpati, G., Andermann, F., and Arnold, D. L. Coenzyme Q10 with multiple vitamins is generally ineffective in treatment of mitochondrial disease. Neurology 1993;43(5
- Malm, C., Svensson, M., Sjoberg, B., Ekblom, B., and Sjodin, B. Supplementation with ubiquinone-10 causes cellular damage during intense exercise. Acta Physiol Scand. 1996;157(4):511-512. PubMed
- Singh, R. B., Wander, G. S., Rastogi, A., Shukla, P. K., Mittal, A., Sharma, J. P., Mehrotra, S. K., Kapoor, R., and Chopra, R. K. Randomized, double-blind placebo-controlled trial of coenzyme Q10 in patients with acute myocardial infarction. Cardiovasc. PubMed
- Digiesi V, Cantini F, and Brodbeck B. Effect of coenzyme Q10 on essential arterial hypertension. Current Therapeutic Research 1990;47(5):841-845.
- Parkinson Study Group QE3 Investigators, Beal MF, Oakes D, et al. A randomized clinical trial of high-dosage coenzyme Q10 in early Parkinson disease: no evidence of benefit. JAMA Neurol. 2014;71(5):543-52.
- Alehagen U, Johansson P, Bjornstedt M, et al. Cardiovascular mortality and N-terminal-proBNP reduced after combined selenium and coenzyme Q10 supplementation: A 5-year prospective randomized double-blind placebo-controlled trial among elderly Swedish citi
- Ho MJ, Li EC, Wright JM. Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension. Cochrane Database Syst Rev. 2016 Mar 3;3:CD007435. doi: 10.1002/14651858.CD007435.pub3. PubMed
- Tabrizi R, Akbari M, Sharifi N, Lankarani KB, Moosazadeh M, Kolahdooz F, et al. The effects of coenzyme Q10 supplementation on blood pressures among patients with metabolic diseases: a systematic review and meta-analysis of randomized controlled trials. PubMed
- Tsai IC, Hsu CW, Chang CH, Tseng PT, Chang KV. Effectiveness of coenzyme Q10 supplementation for reducing fatigue: A systematic review and meta-analysis of randomized controlled trials. Front Pharmacol 2022;13:883251. PubMed
- Yaghini O, Hoseini N, Ghazavi MR, et al. A comparative study on the efficacy of coenzyme Q10 and amitriptyline in the prophylactic treatment of migraine headaches in children: A randomized controlled trial. Adv Biomed Res 2022;11:43. PubMed
- Hansen KS, Mogensen TH, Agergaard J, et al. High-dose coenzyme Q10 therapy versus placebo in patients with post COVID-19 condition: A randomized, phase 2, crossover trial. Lancet Reg Health Eur 2022. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC