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Dietary supplement

Core Cilantro Blend Ingredients & Drug Interactions

by Energetix

Liquid Category: Botanical
Most serious interaction: Major
The interaction bottom line Most serious interaction: Major

Core Cilantro Blend is a dietary supplement by Energetix with 4 active ingredients. Its ingredients are commonly taken for digestive upset and gas, appetite stimulation, mild antimicrobial (topical).Based on those ingredients, 1,273 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Uva Ursi leaf Extract, Cilantro extract, Yellow Dock Root Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Core Cilantro Blend by Energetix

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 4 active ingredients.
  • “Botanical Extract Blend” is a proprietary blend — the label gives one combined amount (1.20 mL) without saying how much of each component you get.

Core Cilantro Blend contains four active botanical extracts: cilantro extract, uva ursi leaf extract, yellow dock root extract, and European goldenrod aerial parts extract. The product is delivered as a liquid in a base of purified water and ethyl alcohol (an inactive preservative).

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

The label doesn't state a purpose we can grade — see each ingredient's own graded uses on its monograph instead.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for these ingredients is limited. Cilantro extract has insufficient reliable evidence for anorexia, anxiety, constipation, diabetes, diarrhea, and indigestion.

Uva ursi is rated possibly ineffective for urinary tract infections and lacks sufficient evidence for bronchitis and benign prostate enlargement. Yellow dock has no effectiveness ratings in the data we hold.

Goldenrod similarly shows insufficient evidence for benign prostate enlargement, dental plaque, kidney stones, and urinary tract infections. None of these ingredients have strong established effectiveness for their traditional uses.

The evidence, ingredient by ingredient Coriander Uva Ursi Yellow Dock Goldenrod

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Cilantro is generally well tolerated in food amounts for most people, though medicinal doses and essential oil should be avoided without medical guidance. Rare cases of anaphylaxis and contact dermatitis have been reported in sensitive individuals, particularly those with occupational exposure.

Uva ursi is generally well tolerated in low doses short-term, but can be toxic at high doses or with prolonged use; it may cause nausea, vomiting, diarrhea, and stomach upset. Yellow dock is well tolerated in food amounts when properly prepared, but raw leaves or high doses can cause kidney stones, low blood calcium, and respiratory effects.

Goldenrod is often well tolerated short-term but has limited human safety data; allergic contact dermatitis and respiratory allergy have been reported in sensitive individuals. Do not use uva ursi, yellow dock, or goldenrod during pregnancy or breastfeeding — safety data are insufficient or the ingredients may cause harm.

Side effects, ingredient by ingredient Coriander Uva Ursi Yellow Dock Goldenrod

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 4 of the 4 matched ingredients can interact with medications — Goldenrod, Coriander, Uva Ursi, Yellow Dock.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications; heart-rhythm medications; lithium.
  • For scale: 1,274 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Core Cilantro Blend, double-check if you use diuretics or digoxin (major concern with yellow dock), warfarin or other blood thinners (moderate concern), antihypertensive or antidiabetes drugs (cilantro), CNS depressants or sedatives (cilantro), photosensitizing drugs, lithium, or medications affected by liver metabolism pathways (CYP2C19, CYP3A4, or glucuronidation). If you're unsure whether your medications fit any of these categories, use the checker below.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Major medication interactions have been identified, and safety information is well characterized.

This blend is for adults with no major medical conditions or medications, though the interaction profile is broad. Anyone taking diuretics, heart medications, blood thinners, blood pressure drugs, blood sugar medications, sedatives, or medications metabolized by the liver should check their specific drugs with the tool on this page before using.

Talk to your pharmacist, especially if you're pregnant, nursing, or have kidney or liver problems.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 24, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Core Cilantro Blend, straight from the product label.

Brand Energetix
Barcode (UPC) 364578010909
Net contents 2 Fluid Ounce(s); 59.1 mL
Market status On market
Date entered into DSLD Jul 24, 2025
DSLD ID 333029
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Core Cilantro Blend by Energetix, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1.2 mL
Maximum serving Sizes:
1.2 mL
Servings per container
49
UPC/BARCODE
364578010909
IngredientAmount% DV
Botanical Extract Blend1.2 mL--
Cilantro extract0 NP--
Uva Ursi leaf Extract0 NP--
Yellow Dock Root Extract0 NP--
European Goldenrod aerial parts extract0 NP--

Other ingredients: Water, Purified, Ethyl Alcohol

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

As a dietary supplement, take 30 to 40 drops orally (in water or juice, if desired) twice daily or as directed by a healthcare professional. Shake well before use.

Precautions

Do not use if neck wrap is broken or missing.

If pregnant or breast-feeding, ask a healthcare professional before use.

Keep out of reach of children.

Storage

Store at room temperature out of direct sunlight.

FDA Statement of Identity

Dietary Supplement

Formulation

Spagyrically processed botanical

See for yourself

Core Cilantro Blend by Energetix label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Core Cilantro Blend by Energetix

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size1.2 mL Dosage formLiquid Servings per container49 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Other (inactive) ingredients: Water, Purified, Ethyl Alcohol. These complete the product’s ingredient list but are not active constituents.

Interaction report

Core Cilantro Blend by Energetix Drug Interactions

Want to check YOUR meds against Core Cilantro Blend?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
1,273Drugs
76 Major 1,153 Moderate 44 Minor

Each ingredient & the kinds of drugs it affects

For each ingredient in Core Cilantro Blend with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Uva Ursi leaf Extract6 drug types · 803 drugs

Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, uva ursi may decrease the metabolism of CYP2C19 substrates.
In vitro, uva ursi appears to inhibit cytochrome CYP2C19. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
In vitro, uva ursi appears to inhibit CYP3A4. This effect has not been reported in humans.

Likelihood Possible Evidence D
Glucuronidated Drugs

Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
In vitro, uva ursi extract appears to strongly inhibit UDP-glucuronosyltransferase (UGT) 1A1 (UGT1A1). However, uva ursi extract does not appear to inhibit UGT1A1 in animal models. This effect has not been reported in humans.

Likelihood Possible Evidence D
Lithium

Theoretically, uva ursi may increase lithium levels, necessitating a decrease in dose.
Uva ursi may have diuretic properties. Diuretics may increase lithium reabsorption with sodium in the proximal tubule of the kidney. Theoretically, uva ursi might reduce excretion and increase levels of lithium.

Likelihood Probable Evidence D
Urinary Acidifying Agents

Effects of uva ursi in the urinary tract may be reduced by urinary acidifying agents.
Uva ursi seems to work best in alkaline urine. Theoretically, taking uva ursi with medications known to acidify the urine may decrease any effects of uva ursi on the urinary tract.

Likelihood Possible Evidence D
P-Glycoprotein Substrates

Theoretically, uva ursi may alter the levels of drugs transported by P-glycoprotein.
In vitro, uva ursi appears to inhibit the multi-drug transporter protein, P-glycoprotein. This effect has not been reported in humans.

Likelihood Possible Evidence D

Cilantro extract4 drug types · 717 drugs

Antidiabetes Drugs

Theoretically, coriander might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Evidence from animal research suggests that coriander fruit and coriander extract can reduce blood glucose levels. Monitor blood glucose levels closely. Dose adjustments might be necessary.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, coriander might increase the risk of hypotension when taken with antihypertensive drugs.
Evidence from animal research suggests that coriander fruit can lower blood pressure.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, coriander might cause additive sedative effects when taken with CNS depressants.
Evidence from animal research suggests that coriander fruit extract has sedative effects.

Likelihood Possible Evidence D
Photosensitizing Drugs

Theoretically, coriander might increase the risk of photosensitivity when taken with photosensitizing drugs.
Evidence from in vitro research suggests that coriandrin, a constituent of coriander, has photosensitizing effects.

Likelihood Possible Evidence D

Yellow Dock Root Extract3 drug types · 78 drugs

Digoxin (Lanoxin)

Theoretically, yellow dock might increase the risk of digoxin toxicity when used long-term or in large amount.
When yellow dock is used chronically or in large amounts, hypokalemia may occur. This might increase the toxic effects of digoxin.

Likelihood Probable Evidence D
Diuretic Drugs

Theoretically, yellow dock might increase the risk of hypokalemia when taken with diuretics.
When yellow dock is used chronically or in large amounts, hypokalemia may occur, and overuse of yellow dock might compound diuretic-induced potassium loss.

Likelihood Probable Evidence D
Warfarin (Coumadin)

Theoretically, the laxative effects of yellow dock might increase the effects of warfarin, including the risk of bleeding.
The anthraquinones in yellow dock have a mild stimulant laxative effect. Consuming excessive amounts can cause diarrhea. Diarrhea can increase the effects of warfarin, increase international normalized ratio (INR), and increase the risk of bleeding.

Likelihood Possible Evidence D

European Goldenrod aerial parts extract1 drug type · 75 drugs

Diuretic Drugs

Theoretically, goldenrod might increase the effects and adverse effects of diuretic drugs.
In vitro and animal research suggests that goldenrod has diuretic effects.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Core Cilantro Blend, from the product label.

Energetix

See all Energetix products
Name
Energetix Corp.
City
Dahlonega
State
GA
ZipCode
30533
Phone Number
800.990.7085
Web Address
www.energetix.com
Pharmacist Counseling Corner

Core Cilantro Blend by Energetix: Common Questions

Does Core Cilantro Blend by Energetix interact with any medications?
Yes. Based on its ingredients, Core Cilantro Blend has a known interaction with 1,273 medications, including 76 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Core Cilantro Blend contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while I'm pregnant?
No — uva ursi, yellow dock, and goldenrod should be avoided during pregnancy because safety data are lacking or they may stimulate the uterus. Cilantro has no pregnancy rating in our data. Talk with your doctor before using any of these ingredients during pregnancy.
Is it safe to breastfeed while taking this?
No — uva ursi, yellow dock, and goldenrod should be avoided while breastfeeding because safety is not established and some compounds may pass into milk. Cilantro has no breastfeeding rating in our data. Check with your doctor or pharmacist.
What does each ingredient in this blend do?
Cilantro is traditionally used for digestion and anxiety. Uva ursi has been used for urinary tract health, though evidence is limited. Yellow dock has been used as a digestive aid and laxative. Goldenrod has been used for urinary and prostate health. None have strong proven effectiveness in the data we hold.
Can I take this long-term?
Uva ursi and yellow dock are not recommended for prolonged use — uva ursi can be toxic at high doses or with extended use, and yellow dock's laxative effects and oxalate content mean it's best used short-term. Goldenrod has limited long-term safety data. Use this product short-term only.
Are there any side effects?
Cilantro is mostly well tolerated but can rarely cause anaphylaxis or contact rash in sensitive people. Uva ursi may cause nausea, vomiting, diarrhea, and stomach upset. Yellow dock can cause diarrhea and dermatitis. Goldenrod can trigger allergic contact dermatitis or respiratory allergy in sensitive individuals.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Core Cilantro Blend is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Core Cilantro Blend label
Sources

Sources & How We Checked

Core Cilantro Blend's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 34 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Coriander 12 references
  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  2. Swanston-Flatt SK, Day C, Bailey CJ, Flatt PR. Traditional plant treatments for diabetes. Studies in normal and streptozotocin diabetic mice. Diabetologia 1990;33:462-4. PubMed
  3. Gray, A. M. and Flatt, P. R. Insulin-releasing and insulin-like activity of the traditional anti-diabetic plant Coriandrum sativum (coriander). Br.J Nutr. 1999;81(3):203-209.
  4. Kanerva, L. and Soini, M. Occupational protein contact dermatitis from coriander. Contact Dermatitis 2001;45(6):354-355. PubMed
  5. Emamghoreishi, M., Khasaki, M., and Aazam, M. F. Coriandrum sativum: evaluation of its anxiolytic effect in the elevated plus-maze. J Ethnopharmacol. 1-15-2005;96(3):365-370. PubMed
  6. Ebo, D. G., Bridts, C. H., Mertens, M. H., and Stevens, W. J. Coriander anaphylaxis in a spice grinder with undetected occupational allergy. Acta Clin Belg. 2006;61(3):152-156. PubMed
  7. Eidi, M., Eidi, A., Saeidi, A., Molanaei, S., Sadeghipour, A., Bahar, M., and Bahar, K. Effect of coriander seed (Coriandrum sativum L.) ethanol extract on insulin release from pancreatic beta cells in streptozotocin-induced diabetic rats. Phytother.Res
  8. Jabeen, Q., Bashir, S., Lyoussi, B., and Gilani, A. H. Coriander fruit exhibits gut modulatory, blood pressure lowering and diuretic activities. J Ethnopharmacol. 2-25-2009;122(1):123-130. PubMed
  9. van Toorenenbergen, A. W. and Dieges, P. H. Immunoglobulin E antibodies against coriander and other spices. J Allergy Clin Immunol. 1985;76(3):477-481. PubMed
  10. Ashwood-Smith, M. J., Warrington, P. J., Jenkins, M., Ceska, O., and Romaniuk, P. J. Photobiological properties of a novel, naturally occurring furoisocoumarin, coriandrin. Photochem.Photobiol. 1989;50(6):745-751. PubMed
  11. Sastre, J., Olmo, M., Novalvos, A., Ibanez, D., and Lahoz, C. Occupational asthma due to different spices. Allergy 1996;51(2):117-120. PubMed
  12. Beikert FC, Anastasiadou Z, Fritzen B, Frank U, Augustin M. Topical treatment of tinea pedis using 6% coriander oil in unguentum leniens: a randomized, controlled, comparative pilot study. Dermatology. 2013;226(1):47-51. PubMed

See these in context on the Coriander monograph →

Uva Ursi 8 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Schulz V, Hansel R, Tyler VE. Rational Phytotherapy: A Physician's Guide to Herbal Medicine. Terry C. Telger, transl. 3rd ed. Berlin, GER: Springer, 1998.
  3. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  4. Wang L, Del Priore LV. Bull's-eye maculopathy secondary to herbal toxicity from uva ursi. Am J Ophthalmol 2004;137:1135-7. PubMed
  5. Beaux, D., Fleurentin, J., and Mortier, F. Effect of extracts of Orthosiphon stamineus Benth, Hieracium pilosella L., Sambucus nigra L. and Arctostaphylos uva-ursi (L.) Spreng. in rats. Phytother.Res 1999;13(3):222-225.
  6. de Arriba SG, Naser B, Nolte KU. Risk assessment of free hydroquinone derived from Arctostaphylos Uva-ursi folium herbal preparations. Int J Toxicol. 2013;32(6):442-453.
  7. Park JB, Kim D, Min JS, et al. Identification and characterization of in vitro inhibitors against UDP-glucuronosyltransferase 1A1 in uva-ursi extracts and evaluation of in vivo uva-ursi-drug interactions. Food Chem Toxicol. 2018;120:651-661. PubMed
  8. Chauhan B, Yu C, Krantis A, et al. In vitro activity of uva-ursi against cytochrome P450 isoenzymes and P-glycoprotein. Can J Physiol Pharmacol. 2007;85(11):1099-107.

See these in context on the Uva Ursi monograph →

Yellow Dock 8 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Foster S, Tyler VE. Tyler's Honest Herbal: A Sensible Guide to the Use of Herbs and Related Remedies. 3rd ed., Binghamton, NY: Haworth Herbal Press, 1993.
  3. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  4. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  5. Ellenhorn MJ, et al. Ellenhorn's Medical Toxicology: Diagnoses and Treatment of Human Poisoning. 2nd ed. Baltimore, MD: Williams & Wilkins, 1997.
  6. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  7. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  8. Latif A, Fichadiya H, Abid F, Capo G. Herbal Teas and Thrombocytopenia: A Curious Case of Yellow Dock and Burdock-Induced Thrombocytopenia. Eur J Case Rep Intern Med 2022;9(3):003247. PubMed

See these in context on the Yellow Dock monograph →

Goldenrod 6 references
  1. Robbers JE, Tyler VE. Tyler's Herbs of Choice: The Therapeutic Use of Phytomedicinals. New York, NY: The Haworth Herbal Press, 1999.
  2. Uter, W., Nohle, M., Randerath, B., and Schwanitz, H. J. Occupational contact urticaria and late-phase bronchial asthma caused by compositae pollen in a florist. Am J Contact Dermat. 2001;12(3):182-184. DOI
  3. Chodera, A., Dabrowska, K., Sloderbach, A., Skrzypczak, L., and Budzianowski, J. [Effect of flavonoid fractions of Solidago virgaurea L on diuresis and levels of electrolytes]. Acta Pol.Pharm 1991;48(5-6):35-37.
  4. Chodera, A., Dabrowska, K., Bobkiewicz-Kozlowska, T., Tkaczyk, J., Skrzypczak, L., and Budzianowski, J. [Effect of leiocarposide on experimental urinary calculi in rats]. Acta Pol.Pharm 1988;45(2):181-186.
  5. Chodera, A., Dabrowska, K., Skrzypczak, L., and Budzianowski, J. [Further studies on the diuretic effect of leiocarposide]. Acta Pol.Pharm 1986;43(5):499-503.
  6. Chodera, A., Dabrowska, K., Senczuk, M., Wasik-Olejnik, A., Skrzypczak, L., Budzianowski, J., and Ellnain-Wojtaszek, M. [Diuretic effect of the glycoside from a plant of the Solidago L. genus]. Acta Pol.Pharm 1985;42(2):199-204.

See these in context on the Goldenrod monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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