Interactions on record — worth a quick check against your medications. Based on 2 of 3 ingredients. Check your meds →
Dietary supplement

Cornsilk Kidney Comfort Ingredients & Drug Interactions

by Botanic Choice

Cornsilk Kidney Comfort label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Cornsilk Kidney Comfort against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Cornsilk Kidney Comfort is a dietary supplement by Botanic Choice with 3 active ingredients. Its ingredients are commonly taken for urinary tract health, mild fluid retention, kidney and bladder support.Based on those ingredients, 266 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Java Tea extract, Juniper powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Cornsilk Kidney Comfort by Botanic Choice

Ask about any prescription or over-the-counter medication and we check it for interactions with Cornsilk Kidney Comfort by Botanic Choice — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Cornsilk Kidney Comfort by Botanic Choice

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Cornsilk Kidney Comfort contains three active ingredients. Java tea extract is included for its traditional use in supporting urinary and kidney function.

Juniper powder has a long history in herbal medicine for similar purposes. Cornsilk powder rounds out the formula.

The product also contains inactive ingredients — gelatin capsule, magnesium stearate, and rice flour — which help hold the capsule together and aid manufacturing.

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Kidney and urinary tract support.
  • We looked for evidence on: Kidney stones (nephrolithiasis), Urinary tract infections (UTIs), Kidney function, Urinary health, Fluid balance.
  • The closest evidence on file: Java Tea is rated "Insufficient Reliable Evidence To Rate" for Urinary tract infections (UTIs) (Natural Medicines).
  • Also on file: Juniper is rated "Insufficient Reliable Evidence To Rate" for Kidney stones (nephrolithiasis), Urinary tract infections (UTIs).

We hold insufficient evidence to rate any of these ingredients for kidney or urinary tract support. Java tea's effectiveness for high blood pressure and urinary tract infections hasn't been established in reliable trials.

Juniper shows equally limited evidence for the conditions listed in our data — GERD, rheumatoid arthritis, UTIs, wound healing, kidney stones, and bronchitis. In short, the evidence we have doesn't tell us whether this product works for its intended purpose.

The evidence, ingredient by ingredient Java Tea Juniper

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Java tea is generally well tolerated short-term, though human safety data are sparse. It should be avoided during pregnancy and breastfeeding because there isn't enough data to know it's safe.

Juniper is tolerated in food amounts, but medicinal doses can irritate the kidneys and shouldn't be used long-term. Juniper is unsafe in pregnancy because it may affect the uterus, and breastfeeding safety data are insufficient.

Topically, juniper can cause skin irritation or allergies, though this product is taken by mouth. We have no adverse-effect data for cornsilk powder.

Side effects, ingredient by ingredient Java Tea Juniper

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Java Tea, Juniper.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications; lithium.
  • For scale: 266 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your pharmacist if you take antihypertensive drugs (blood pressure medications), antidiabetes drugs (blood sugar medications), diuretics (water pills), or lithium. These are the medication types with documented interactions — some moderate, some minor — that could change how they work in your body.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product is a traditional herbal blend for kidney and urinary comfort, but we don't have strong evidence that it works. If you take blood pressure medicine, diabetes medication, a diuretic, or lithium, you'll need to talk with your pharmacist before starting it — the interactions could affect how those drugs work.

Pregnant or breastfeeding? Skip it and ask your doctor for safer alternatives.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Cornsilk Kidney Comfort, straight from the product label.

Brand Botanic Choice
Barcode (UPC) 703308811025
Net contents 30 Capsule(s)
Market status On market
Date entered into DSLD Apr 25, 2019
DSLD ID 199798
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Cornsilk Kidney Comfort by Botanic Choice, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
UPC/BARCODE
703308811025
IngredientAmount% DV
Cornsilk powder425 mg--
Java Tea extract50 mg--
Juniper powder60 mg--

Other ingredients: Gelatin Capsule, Magnesium Stearate, Rice Flour

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Dietary Supplement

General Statements

Trusted since 1910 Essentials

Kidney & urinary support

Formulation

Gluten free Non GMO

Seals/Symbols

Gluten free Non GMO

Suggested/Recommended/Usage/Directions

Suggested Use: Take 1 capsule daily, with a meal, as a dietary supplement, or as directed by a physician.

Precautions

Warning: If you are taking any medications or are pregnant or nursing, do not use prior to consulting a physician.

For your protection, this container has an outer safety seal. (Do not accept if missing or broken.)

Keep out of reach of children

FDA Disclaimer Statement

This statement has not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Storage

Store in a dry, cool place.

Brand IP Statement(s)

IBG Indiana Botanic Gardens

General

C-108890

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Cornsilk Kidney Comfort by Botanic Choice label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Cornsilk Kidney Comfort label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Cornsilk Kidney Comfort by Botanic Choice

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Cornsilk powder

425 mg per serving

Java Tea extract

Interacts with
173 drugs
50 mg per serving Form: Sinensetin

Java Tea is a Southeast Asian herb traditionally used as a gentle diuretic and for urinary tract and kidney support. Some early lab, animal, and small...

Java Tea extract monograph & interactions

Juniper powder

Interacts with
162 drugs
60 mg per serving

Juniper berry is a traditional herb best known for flavoring gin and for its folk use as a diuretic and digestive aid. Solid human evidence for its he...

Juniper powder monograph & interactions

Other (inactive) ingredients: Gelatin Capsule, Magnesium Stearate, Rice Flour. These complete the product’s ingredient list but are not active constituents.

Interaction report

Cornsilk Kidney Comfort by Botanic Choice Drug Interactions

Want to check YOUR meds against Cornsilk Kidney Comfort?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
266Drugs
259 Moderate 7 Minor

Ingredients driving the most interactions

Java Tea extract 173
Juniper powder 162

Individual Drug Interactions

The ingredients in Cornsilk Kidney Comfort interact with 266 drugs. Click any drug to see the details.

2 of the 3 ingredients in Cornsilk Kidney Comfort interact with drugs. Each result below shows which ingredient is responsible. Java Tea extract Juniper powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Cornsilk Kidney Comfort with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Java Tea extract2 drug types · 173 drugs

Antihypertensive Drugs

Some preliminary clinical evidence suggests that Java tea has antihypertensive effects. Further, animal research suggests that Java tea has diuretic properties. Theoretically, taking Java tea with other antihypertensive drugs might increase the effects and risk for hypotension with these drugs.

Likelihood Probable Evidence D
Lithium

Animal research suggests that Java tea has diuretic properties. Theoretically, due to these effects, Java tea might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
Java Tea extract full monograph & interactions

Juniper powder3 drug types · 162 drugs

Antidiabetes Drugs

Theoretically, taking juniper berry with antidiabetes medications might cause additive hypoglycemia.
Animal research shows that juniper berry can lower blood glucose.

Likelihood Possible Evidence D
Diuretic Drugs

Theoretically, juniper berry might increase the risk of adverse effects from diuretic drugs.
Juniper berry is thought to have mild diuretic effects.

Likelihood Possible Evidence D
Lithium

Theoretically, juniper berry might reduce lithium excretion and increase serum levels of lithium.
Juniper berry is thought to have mild diuretic effects.

Likelihood Possible Evidence D
Juniper powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Cornsilk Kidney Comfort, from the product label.

Botanic Choice

See all Botanic Choice products
Name
Indiana Botanic Gardens, Inc.
Street Address
3401 W. 37th Ave.
City
Hobart
State
IN
ZipCode
46342
Phone Number
1-800-644-8327
Web Address
www.botanicchoice.com
Pharmacist Counseling Corner

Cornsilk Kidney Comfort by Botanic Choice: Common Questions

Does Cornsilk Kidney Comfort by Botanic Choice interact with any medications?
Yes. Based on its ingredients, Cornsilk Kidney Comfort has a known interaction with 266 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Cornsilk Kidney Comfort contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while pregnant or breastfeeding?
No. Juniper is unsafe in pregnancy because it may affect the uterus. Java tea and juniper should both be avoided while breastfeeding because there isn't enough safety data. Talk with your doctor about safer options.
Will this product actually help my kidneys or urinary tract?
The evidence we hold isn't strong enough to say. Both java tea and juniper have insufficient reliable evidence for urinary tract infections and related kidney support. You're working with a traditional formula, not one backed by solid clinical data yet.
What is cornsilk powder, and why is it in here?
Cornsilk is the silky fibers from an ear of corn. It's used traditionally in herbal blends aimed at kidney and urinary support, though we have no data on how well it works.
Is juniper safe to take long-term?
No. Our data caution against long-term use of juniper in medicinal doses because it can irritate the kidneys. This product is meant for short-term use.
What side effects might I notice from this product?
We have no adverse-effect data for cornsilk. Java tea is generally well tolerated short-term. Juniper in low doses and short-term use is usually well tolerated, but since topical application can cause skin irritation or allergies, mention any unusual reactions to your pharmacist.
Why do I need to check my medications with my pharmacist?
Both java tea and juniper can interact with common medications — especially blood pressure drugs, diabetes drugs, water pills, and lithium. These interactions could make your medicines less effective or cause side effects, so a quick check is worth the peace of mind.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Cornsilk Kidney Comfort is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Cornsilk Kidney Comfort label
Go deeper

The Full Monographs Behind Cornsilk Kidney Comfort’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Java Tea

Interacts with 173 drugs

Java Tea is a Southeast Asian herb traditionally used as a gentle diuretic and for urinary tract and kidney support. Some early lab, animal, and small human studies are encouraging, but high...

Read the full Java Tea monograph → Herb & supplement monograph

Juniper

Interacts with 162 drugs

Juniper berry is a traditional herb best known for flavoring gin and for its folk use as a diuretic and digestive aid. Solid human evidence for its health benefits is limited, and it can irr...

Read the full Juniper monograph →
Sources

Sources & How We Checked

Cornsilk Kidney Comfort's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 9 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Java Tea 2 references
  1. Cicero AF, De Sando V, Izzo R, Vasta A, Trimarco A, Borghi C. Effect of a combined nutraceutical containing Orthosiphon stamineus effect on blood pressure and metabolic syndrome components in hypertensive dyslipidaemic patients: a randomized clinical tria
  2. Vahlensieck W, Lorenz H, Schumacher-Stimpfl A, Fischer R, Naber KG. Effect of a herbal therapy on clinical symptoms of acute lower uncomplicated urinary tract infections in women: Secondary analysis from a randomized controlled trial. Antibiotics (Basel). PubMed

See these in context on the Java Tea monograph →

Juniper 7 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  3. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  4. Robbers JE, Tyler VE. Tyler's Herbs of Choice: The Therapeutic Use of Phytomedicinals. New York, NY: The Haworth Herbal Press, 1999.
  5. Sanchez de Medina F, Gamez MJ, Jimenez I, et al. Hypoglycemic activity of juniper "berries." Planta Med 1994;60:197-200. PubMed
  6. Swanston-Flatt SK, Day C, Bailey CJ, Flatt PR. Traditional plant treatments for diabetes. Studies in normal and streptozotocin diabetic mice. Diabetologia 1990;33:462-4. PubMed
  7. Tammaro A, Adebanjo GAR, Chello C, et al. Bullous dermatitis caused by common juniper. Contact Dermatitis. 2020. PubMed

See these in context on the Juniper monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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