Creatine Select Orange Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Creatine Select Orange against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Creatine Select Orange is a dietary supplement by Beverly International with 6 active ingredients. Its ingredients are commonly taken for replacing fluids and electrolytes, preventing dehydration during exercise or illness, treating low blood sodium (under medical care).Based on those ingredients, 220 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Sodium, Potassium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Creatine Select Orange by Beverly International
Ask about any prescription or over-the-counter medication and we check it for interactions with Creatine Select Orange by Beverly International — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Creatine Select Orange by Beverly International
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Creatine Select Orange contains 6 active ingredients: Sodium, Potassium, CarnoSyn (a branded form of beta-alanine), Creatine Monohydrate, Potassium Phosphate, and Sodium Phosphate. Creatine and beta-alanine are amino acid derivatives used to support muscle performance during exercise.
Sodium and potassium are electrolytes that help with muscle function and hydration, though they're present here in supplemental amounts. The product also includes inactive ingredients like maltodextrin, citric acid, mandarin orange flavor, and various sweeteners and thickeners.
Does it work?
Moderate evidence
Creatine Monohydrate is possibly effective for muscle strength, athletic performance, sarcopenia (age-related muscle loss), and cerebral creatine deficiency syndromes. Beta-alanine (CarnoSyn) is possibly effective for athletic and physical performance.
The sodium and potassium in this product have effectiveness ratings for specific medical conditions—sodium for cystic fibrosis (likely effective) and amphotericin B nephrotoxicity (possibly effective)—but those uses fall outside a general fitness or sports supplement context. Neither ingredient is established for the other conditions we have data for.
How safe is it?
Well-documented data
Creatine Monohydrate is generally well tolerated in healthy adults, though the most common side effects are dehydration, diarrhea, muscle cramps, and water retention. Beta-alanine commonly causes a harmless tingling sensation (paresthesia) and flushing, especially on the scalp and face, usually starting within 20 minutes of taking it and lasting about an hour.
Sodium and potassium are essential nutrients but in high amounts can strain the heart and kidneys; the safety notes emphasize avoiding excess intake and checking with your doctor before supplementing. Safety during pregnancy and breastfeeding has not been established for creatine or beta-alanine, and the data on sodium and potassium in pregnancy is mixed (sodium is listed as possibly unsafe)—talk with your doctor or pharmacist before use if you're pregnant or nursing.
Meds to double-check
Moderate interaction found
Before taking Creatine Select Orange, check with your pharmacist if you take potassium-sparing diuretics, ACE inhibitors, or ARBs—all carry a Moderate risk of high blood potassium. Also check if you're on blood pressure medications (antihypertensives), lithium, corticosteroids, didanosine, sodium phosphate bowel prep, or tolvaptan, as these interact with the sodium in this product.
Use the medication checker below to verify your specific drugs.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This is a creatine and beta-alanine product designed to support muscle performance in athletes and people doing resistance training. It's generally well tolerated, but because it contains sodium and potassium supplements, anyone on heart, blood pressure, kidney, or mood medications should check their specific drugs with a pharmacist first.
Expect harmless tingling from the beta-alanine and possible water retention from creatine. If you're pregnant, nursing, or have kidney disease, talk to your doctor before starting.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 6 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Creatine Select Orange, straight from the product label.
| Brand | Beverly International |
|---|---|
| Barcode (UPC) | 857254000597 |
| Net contents | 480 Gram(s); 16.9 Ounce(s) |
| Market status | On market |
| Date entered into DSLD | Jun 25, 2025 |
| DSLD ID | 332817 |
| Product type | Other Combinations |
| Supplement form | Powder |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Creatine Select Orange by Beverly International, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Sodium | 60 mg | 3% |
| Potassium | 310 mg | 7% |
| CarnoSyn | 1 Gram(s) | -- |
| Creatine Monohydrate | 5 Gram(s) | -- |
| Potassium Phosphate | 700 mg | -- |
| Calories | 15 Calorie(s) | -- |
| Total Carbohydrate | 4 Gram(s) | 1% |
| Sodium Phosphate | 300 mg | -- |
Other ingredients: Maltodextrin, Citric Acid, Mandarin Orange, MagnaSweet, Malic Acid, Guar Gum, Gum Acacia, Silicon Dioxide, Annatto, Powder, Sucralose, Acesulfame Potassium, Cinnamon bark extract, Dextrose, Propylene Glycol
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Hard-training athletes use Creatine Select for rapid gains in strength, stamina, and mass, without the bloating or puffiness caused by run-of-the-mill creatine products. Creatine Select is formulated with the most proven form of creatine, plus phosphates, essential electrolytes, and beta-alanine, all wrapped in tangy, natural flavor. Creatine Select succeeds where other creatine products fail, turning non-responders into responders, time and time again.
Creatine + Phosphates + Beta-Alanine for muscle strength, stamina & size Orange natural flavor
CarnoSyn Carnosine Synthesizer
Suggested/Recommended/Usage/Directions
Use: Take 1 scoop daily. Mix each scoop with 4-6 oz of water and drink. Loading cycle for fast results: Take 1 scoop 4 times daily for 5 consecutive days. Once loading is complete, maintain by taking 1 scoop daily. You may also wish to combine with Up-Lift or Muscle Synergy pre-workout.
FDA Disclaimer Statement
These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
Formulation
100% money-back guarantee If you're not 100% satisfied after using this product for 60 days, we will refund your money. No questions asked.
General Statements
Questions or comments? Call (800) 781-3475 or email [email protected].
Brand IP Statement(s)
Beverly International 1967
Natural Alternatives International (NAI) is the owner of patents as listed on www.carnosyn.com and registered trademark of CarnoSyn.
FDA Statement of Identity
Dietary Supplement
Precautions
Warning: Consult your physician prior to using this product if you are under 18 years of age; pregnant; nursing; trying to become pregnant; taking medication; or have a medical condition.
Warning: Consult your physician prior to using this product if you are under 18 years of age; pregnant; nursing; trying to become pregnant; taking medication; or have a medical condition. Keep out of reach of chidlren.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Creatine Select Orange by Beverly International label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Creatine Select Orange by Beverly International
These are the 6 active ingredients this product is made of. Select any to open its full monograph.
Serving size12 Gram(s) Dosage formPowder Servings per container40 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Sodium
Interacts with205 drugs
Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets g...
Sodium monograph & interactionsPotassium
Interacts with62 drugs
Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanc...
Potassium monograph & interactionsCarnoSyn
No knowninteractions
Beta-alanine is an amino acid taken mostly by athletes to raise muscle carnosine, which may help buffer acid and reduce fatigue during short, high-int...
CarnoSyn monograph & interactionsCreatine Monohydrate
No knowninteractions
Creatine is one of the most studied sports supplements, with solid evidence that it can boost strength and performance during short, high-intensity ac...
Creatine Monohydrate monograph & interactionsPotassium Phosphate
Interacts with62 drugs
Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanc...
Potassium Phosphate monograph & interactionsSodium Phosphate
Interacts with205 drugs
Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets g...
Sodium Phosphate monograph & interactionsOther (inactive) ingredients: Maltodextrin, Citric Acid, Mandarin Orange, MagnaSweet, Malic Acid, Guar Gum, Gum Acacia, Silicon Dioxide, Annatto, Powder, Sucralose, Acesulfame Potassium, Cinnamon bark extract, Dextrose, Propylene Glycol. These complete the product’s ingredient list but are not active constituents.
Creatine Select Orange by Beverly International Drug Interactions
HelloPharmacist Interaction Report
Creatine Select Orange by Beverly International contains sodium and potassium, both of which interact with a number of medications.
The most serious concern is potassium's effect on potassium-sparing diuretics (water pills that preserve potassium), ACE inhibitors, and ARBs—all Moderate severity interactions that raise the risk of dangerously high blood potassium levels (hyperkalemia). Sodium poses Moderate interactions with blood pressure medications (antihypertensives), which it may weaken, and with lithium, a mood stabilizer where sodium changes can trigger toxicity.
Sodium also interacts with corticosteroids, didanosine (an HIV drug), sodium phosphate bowel prep, and tolvaptan—all Moderate—by raising sodium levels too high (hypernatremia).
Read the full breakdown — every affected drug type, severity by severity
CarnoSyn (beta-alanine) and Creatine Monohydrate were checked and no interactions are documented in our data. Altogether, these interactions span 218 individual medications.
Because this product contains electrolytes (sodium and potassium) in supplemental form, it's important to check your exact medications before you start—especially if you take heart or blood pressure drugs, lithium, or any water pill. Use the medication checker on this page to see if any of yours are affected.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Creatine Select Orange?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Creatine Select Orange interact with 220 drugs. Click any drug to see the details.
2 of the 6 ingredients in Creatine Select Orange interact with drugs. Each result below shows which ingredient is responsible. Sodium Potassium
HydroflumethiazideSaluron
How Hydroflumethiazide interacts with Creatine Select Orange — through 1 ingredient. Tap an ingredient for the detail:
Sodium PhosphateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium Phosphate + Hydroflumethiazide interactionHydroflumethiazide, ReserpineSalutensin, Salutensin-Demi
How Hydroflumethiazide, Reserpine interacts with Creatine Select Orange — through 1 ingredient. Tap an ingredient for the detail:
Sodium PhosphateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium Phosphate + Hydroflumethiazide, Reserpine interactionIloprostAurlumyn, Ventavis
How Iloprost interacts with Creatine Select Orange — through 1 ingredient. Tap an ingredient for the detail:
Sodium PhosphateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium Phosphate + Iloprost interactionIndapamideLozide, Lozol
How Indapamide interacts with Creatine Select Orange — through 1 ingredient. Tap an ingredient for the detail:
Sodium PhosphateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium Phosphate + Indapamide interactionIrbesartanAprovel, Avapro
How Irbesartan interacts with Creatine Select Orange — through 2 ingredients. Tap an ingredient for the detail:
Potassium PhosphateAngiotensin Receptor Blockers (arbs) Moderate
Interaction Summary
Using ARBs with high doses of potassium increases the risk of hyperkalemia.
Read the full Potassium Phosphate + Irbesartan interactionSodium PhosphateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium Phosphate + Irbesartan interactionIrbesartan, HydrochlorothiazideCoAprovel
How Irbesartan, Hydrochlorothiazide interacts with Creatine Select Orange — through 2 ingredients. Tap an ingredient for the detail:
Potassium PhosphateAngiotensin Receptor Blockers (arbs) Moderate
Interaction Summary
Using ARBs with high doses of potassium increases the risk of hyperkalemia.
Read the full Potassium Phosphate + Irbesartan, Hydrochlorothiazide interactionSodium PhosphateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium Phosphate + Irbesartan, Hydrochlorothiazide interactionIsosorbide Dinitrate, HydralazineBiDil
How Isosorbide Dinitrate, Hydralazine interacts with Creatine Select Orange — through 1 ingredient. Tap an ingredient for the detail:
Sodium PhosphateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium Phosphate + Isosorbide Dinitrate, Hydralazine interactionIsradipineDynacirc CR
How Isradipine interacts with Creatine Select Orange — through 1 ingredient. Tap an ingredient for the detail:
Sodium PhosphateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium Phosphate + Isradipine interactionLabetalolNormodyne, Trandate
How Labetalol interacts with Creatine Select Orange — through 1 ingredient. Tap an ingredient for the detail:
Sodium PhosphateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium Phosphate + Labetalol interactionLercanidipine HydrochlorideZanidip
How Lercanidipine Hydrochloride interacts with Creatine Select Orange — through 1 ingredient. Tap an ingredient for the detail:
Sodium PhosphateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium Phosphate + Lercanidipine Hydrochloride interactionLevamlodipineConjupri
How Levamlodipine interacts with Creatine Select Orange — through 1 ingredient. Tap an ingredient for the detail:
Sodium PhosphateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium Phosphate + Levamlodipine interactionLisinoprilPrinivil, Qbrelis, Zestril
How Lisinopril interacts with Creatine Select Orange — through 2 ingredients. Tap an ingredient for the detail:
Potassium PhosphateAce Inhibitors (aceis) Moderate
Interaction Summary
Using ACEIs with high doses of potassium increases the risk of hyperkalemia.
Read the full Potassium Phosphate + Lisinopril interactionSodium PhosphateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium Phosphate + Lisinopril interactionLithium Carbonate (prescription Drug)Eskalith, Lithium Carbonate
How Lithium Carbonate (prescription Drug) interacts with Creatine Select Orange — through 1 ingredient. Tap an ingredient for the detail:
Sodium PhosphateLithium Moderate
Interaction Summary
Altering dietary intake of sodium might alter the levels and clinical effects of lithium.
Read the full Sodium Phosphate + Lithium Carbonate (prescription Drug) interactionLosartan PotassiumCozaar
How Losartan Potassium interacts with Creatine Select Orange — through 2 ingredients. Tap an ingredient for the detail:
Potassium PhosphateAngiotensin Receptor Blockers (arbs) Moderate
Interaction Summary
Using ARBs with high doses of potassium increases the risk of hyperkalemia.
Read the full Potassium Phosphate + Losartan Potassium interactionSodium PhosphateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium Phosphate + Losartan Potassium interactionMacitentanOpsumit
How Macitentan interacts with Creatine Select Orange — through 1 ingredient. Tap an ingredient for the detail:
Sodium PhosphateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium Phosphate + Macitentan interactionMacitentan, TadalafilOpsynvi
How Macitentan, Tadalafil interacts with Creatine Select Orange — through 1 ingredient. Tap an ingredient for the detail:
Sodium PhosphateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium Phosphate + Macitentan, Tadalafil interactionMannitolBronchitol, Osmitrol
How Mannitol interacts with Creatine Select Orange — through 1 ingredient. Tap an ingredient for the detail:
Sodium PhosphateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium Phosphate + Mannitol interactionMecamylamineInversine
How Mecamylamine interacts with Creatine Select Orange — through 1 ingredient. Tap an ingredient for the detail:
Sodium PhosphateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium Phosphate + Mecamylamine interactionMethazolamideNeptazane
How Methazolamide interacts with Creatine Select Orange — through 1 ingredient. Tap an ingredient for the detail:
Sodium PhosphateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium Phosphate + Methazolamide interactionMethyclothiazideAquatensen, Enduron
How Methyclothiazide interacts with Creatine Select Orange — through 1 ingredient. Tap an ingredient for the detail:
Sodium PhosphateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium Phosphate + Methyclothiazide interactionMethyclothiazide, PargylineEutron
How Methyclothiazide, Pargyline interacts with Creatine Select Orange — through 1 ingredient. Tap an ingredient for the detail:
Sodium PhosphateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium Phosphate + Methyclothiazide, Pargyline interactionMethyclothiazide, ReserpineDiutensen-R
How Methyclothiazide, Reserpine interacts with Creatine Select Orange — through 1 ingredient. Tap an ingredient for the detail:
Sodium PhosphateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium Phosphate + Methyclothiazide, Reserpine interactionMethyldopaAldomet, Methyldopa
How Methyldopa interacts with Creatine Select Orange — through 1 ingredient. Tap an ingredient for the detail:
Sodium PhosphateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium Phosphate + Methyldopa interactionMethylprednisoloneMedrol, Medrol Dosepak
How Methylprednisolone interacts with Creatine Select Orange — through 1 ingredient. Tap an ingredient for the detail:
Sodium PhosphateCorticosteroids Moderate
Interaction Summary
Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Read the full Sodium Phosphate + Methylprednisolone interactionMetolazoneDiulo, Mykrox, Zaroxolyn
How Metolazone interacts with Creatine Select Orange — through 1 ingredient. Tap an ingredient for the detail:
Sodium PhosphateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium Phosphate + Metolazone interactionMetoprololLopressor, Toprol XL
How Metoprolol interacts with Creatine Select Orange — through 1 ingredient. Tap an ingredient for the detail:
Sodium PhosphateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium Phosphate + Metoprolol interactionMinoxidilLoniten, Minoxidil, Rogaine
How Minoxidil interacts with Creatine Select Orange — through 1 ingredient. Tap an ingredient for the detail:
Sodium PhosphateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium Phosphate + Minoxidil interactionMoexiprilUnivasc
How Moexipril interacts with Creatine Select Orange — through 2 ingredients. Tap an ingredient for the detail:
Potassium PhosphateAce Inhibitors (aceis) Moderate
Interaction Summary
Using ACEIs with high doses of potassium increases the risk of hyperkalemia.
Read the full Potassium Phosphate + Moexipril interactionSodium PhosphateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium Phosphate + Moexipril interactionMoxonidinePhysiotens
How Moxonidine interacts with Creatine Select Orange — through 1 ingredient. Tap an ingredient for the detail:
Sodium PhosphateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium Phosphate + Moxonidine interactionNadololCorgard, Nadolol
How Nadolol interacts with Creatine Select Orange — through 1 ingredient. Tap an ingredient for the detail:
Sodium PhosphateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium Phosphate + Nadolol interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Creatine Select Orange with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Sodium
Antihypertensive Drugs
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
High intake of dietary sodium can increase systolic and diastolic blood pressure. Also, high intake of sodium may necessitate increased use of antihypertensive medications to achieve blood pressure control in some patients, such as those with chronic kidney disease.
Corticosteroids
Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Mineralocorticoids and some glucocorticoids (corticosteroids) cause sodium retention. This effect is dose-related and depends on mineralocorticoid potency. It is most common with hydrocortisone, cortisone, and fludrocortisone, followed by prednisone and prednisolone.
Didanosine (Videx)
Concomitant use of didanosine with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia.
Didanosine formulations contain a significant amount of sodium.
Lithium
Altering dietary intake of sodium might alter the levels and clinical effects of lithium.
High sodium intake can reduce plasma concentrations of lithium by increasing lithium excretion. Reducing sodium intake can significantly increase plasma concentrations of lithium and cause lithium toxicity in patients being treated with lithium carbonate. Stabilizing sodium intake is shown to reduce the percentage of patients with lithium level fluctuations above 0.8 mEq/L. Patients taking lithium should avoid significant alterations in their dietary intake of sodium.
Sodium Phosphates
Theoretically, concomitant use of sodium phosphate with sodium supplements might increase the risk of hypernatremia.
Use of high doses (> 45 mL in 24 hours) of sodium phosphate, such as those used for bowel cleansing before surgery, can lead to serious electrolyte disturbances, including hypernatremia. The risk of hypernatremia is highest in the elderly and people with other risk factors for electrolyte disturbances.
Sodium-Containing Drugs
Concomitant use of sodium-containing drugs with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia and long-term sodium-related complications.
The Chronic Disease Risk Reduction (CDRR) intake level of 2.3 grams of sodium daily indicates the intake at which it is believed that chronic disease risk increases for the apparently healthy population. Some medications contain high quantities of sodium. When used in conjunction with sodium supplements or high-sodium diets, the CDRR may be exceeded. Additionally, concomitant use may increase the risk for hypernatremia; this risk is highest in the elderly and people with other risk factors for electrolyte disturbances.
Tolvaptan (Samsca)
Theoretically, concomitant use of tolvaptan with sodium might increase the risk of hypernatremia.
Tolvaptan is a vasopressin receptor 2 antagonist that is used to increase sodium levels in patients with hyponatremia. Patients taking tolvaptan should use caution with the use of sodium salts such as sodium chloride.
Potassium
Ace Inhibitors (Aceis)
Using ACEIs with high doses of potassium increases the risk of hyperkalemia.
ACEIs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.
Angiotensin Receptor Blockers (Arbs)
Using ARBs with high doses of potassium increases the risk of hyperkalemia.
ARBs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.
Potassium-Sparing Diuretics
Concomitant use increases the risk of hyperkalemia.
Using potassium-sparing diuretics with potassium supplements increases the risk of hyperkalemia.
Brand information
Manufacturer and brand details for Creatine Select Orange, from the product label.
Beverly International
See all Beverly International products- Name
- Beverly International Nutrition, Inc
- City
- Cold Spring
- State
- KY
- ZipCode
- 41076
- Phone Number
- (800) 781-3475
- Web Address
- www.BeverlyInternational.com
Creatine Select Orange by Beverly International: Common Questions
Does Creatine Select Orange by Beverly International interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will this product help me build muscle or improve my workout performance?
What's that tingling feeling I might get from taking this?
Why does this product have sodium and potassium in it?
Can I take this if I'm pregnant or breastfeeding?
What side effects should I expect?
Is this safe if I have kidney disease or take kidney medications?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Creatine Select Orange is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Creatine Select Orange’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sodium
Interacts with 205 drugsSodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets get more than enough—often too much—from...
Read the full Sodium monograph → Herb & supplement monographPotassium
Interacts with 62 drugsPotassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanced diet rich in fruits and vegetables. P...
Read the full Potassium monograph → Herb & supplement monographBeta-alanine
Beta-alanine is an amino acid taken mostly by athletes to raise muscle carnosine, which may help buffer acid and reduce fatigue during short, high-intensity exercise. The evidence is moderat...
Read the full Beta-alanine monograph → Herb & supplement monographCreatine
Creatine is one of the most studied sports supplements, with solid evidence that it can boost strength and performance during short, high-intensity activities like weightlifting and sprintin...
Read the full Creatine monograph →Sources & How We Checked
Creatine Select Orange's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 149 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Sodium 38 references
- Garabedian-Ruffalo SM, Ruffalo RL. Drug and nutrient interactions. Am Fam Physician 1986;33:165-74.
- Food and Drug Administration Science Background: Safety of Sodium Phosphates Oral Solution. September 17, 2001. Available at: http://www.fda.gov/cder/drug/safety/sodiumphospate.htm
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