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Dietary supplement

Cumin Ingredients & Drug Interactions

by doTERRA

Cumin label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Cumin against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Cumin is a dietary supplement by doTERRA with 1 active ingredient. Its ingredients are commonly taken for digestive upset, bloating and gas, appetite stimulation.Based on those ingredients, 211 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Cumin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Cumin by doTERRA

Ask about any prescription or over-the-counter medication and we check it for interactions with Cumin by doTERRA — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Cumin by doTERRA

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 23, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

doTERRA Cumin is a single-ingredient liquid supplement containing cumin. Cumin is a spice from the seeds of Cuminum cyminum, traditionally used in cooking and folk medicine.

This product delivers the plant in liquid form rather than powder or whole seed.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Cumin product and its label doesn't state a use — see Cumin's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence we hold for cumin doesn't support it for any specific condition. Studies have looked at metabolic syndrome, prediabetes (impaired glucose tolerance), fatty liver disease (nonalcoholic steatohepatitis), obesity, and cholesterol problems, but the data is too limited or conflicting to say whether cumin works for any of them.

If you're considering it for one of these reasons, talk it over with your doctor about what the science actually shows.

The evidence, ingredient by ingredient Cumin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Cumin as a food spice is generally well tolerated in the amounts we eat in cooking. However, the safety data for larger supplement or medicinal doses is limited — so stick to food amounts unless you've checked with your doctor or pharmacist first.

Short-term use of cumin powder and essential oil appears to be well tolerated in most people. The most common side effect is stomach upset.

Rarely, cumin can cause allergic reactions, including a serious reaction called anaphylaxis, in sensitive individuals. Topically, it may cause contact dermatitis in people with sensitive skin.

We don't have enough data on cumin's safety in pregnancy or while breastfeeding — talk with your doctor or pharmacist for personalized advice if you're pregnant, planning to become pregnant, or nursing.

Side effects, ingredient by ingredient Cumin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Cumin.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 211 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before using this product if you take blood thinners (like warfarin or clopidogrel), diabetes drugs (like insulin or metformin), or rifampin. All three have documented Moderate-severity interactions with cumin.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Cumin is a common kitchen spice, but as a supplement at higher doses, the safety data is thin. If you take blood thinners, diabetes medications, or the antibiotic rifampin, you'll want to check with your doctor or pharmacist before starting this product.

For other medications, use the checker below to see if cumin is a concern for you specifically.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 24, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Cumin, straight from the product label.

Brand doTERRA
Net contents 5 mL; 0.16 fl. Oz.
Market status On market
Date entered into DSLD Jun 24, 2019
DSLD ID 202772
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Cumin by doTERRA, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Drop(s)
Maximum serving Sizes:
1 Drop(s)
Servings per container
85
IngredientAmount% DV
Cumin60 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

For aromatic or topical use. Diffuse aromatically or, to apply topically, dilute with a carrier oil to minimize skin sensitivity.

For internal use dilute one drop in 4 fl. oz. of liquid.

Precautions

Caution: Possible skin sensitivity.

Keep out of reach of children.

If pregnant or under a doctor's care, consult your physician.

Avoid contact with eyes, inner ears, and sensitive areas. Avoid sunlight or UV rays for up to 12 hours after applying product.

General

v2 49470001

Formula

Cuminum cyminum

FDA Statement of Identity

Essential Oil Supplement

Brand IP Statement(s)

CPTG Certified Pure Therapeutic Grade

General Statements

Peel back for more information.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Cumin by doTERRA label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Cumin label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Cumin by doTERRA

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Drop(s) Dosage formLiquid Servings per container85 Amounts shown are per serving.

Cumin

Interacts with
211 drugs
60 mg per serving

Cumin is a common cooking spice that has a long history in traditional medicine for digestion and other complaints. Food amounts are generally safe fo...

Cumin monograph & interactions
Interaction report

Cumin by doTERRA Drug Interactions

Want to check YOUR meds against Cumin?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
211Drugs
211 Moderate

Ingredients driving the most interactions

Cumin 211

Individual Drug Interactions

The ingredients in Cumin interact with 211 drugs. Click any drug to see the details.

1 of the 1 ingredient in Cumin interact with drugs. Each result below shows which ingredient is responsible. Cumin

Each ingredient & the kinds of drugs it affects

For each ingredient in Cumin with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Cumin3 drug types · 211 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, cumin might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
In vitro evidence suggests that cumin can inhibit platelet aggregation. Theoretically, cumin might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, cumin might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research suggests that cumin can lower blood sugar in diabetic animals. However, research in humans with and without diabetes has found conflicting results.

Likelihood Probable Evidence D
Rifampin (Rifadin)

Theoretically, cumin might increase the effects and adverse effects of rifampin.
Animal research suggests that an aqueous extract of cumin containing a specific flavonoid glycoside can increase the bioavailability and plasma levels of rifampin.

Likelihood Possible Evidence D
Cumin full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Cumin, from the product label.

doTERRA

See all doTERRA products
Name
doTERRA Intl, LLC
Street Address
389 South 1300 West
City
Pleasant Grove
State
UT
ZipCode
84062
Pharmacist Counseling Corner

Cumin by doTERRA: Common Questions

Does Cumin by doTERRA interact with any medications?
Yes. Based on its ingredients, Cumin has a known interaction with 211 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Cumin contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is cumin safe to use if I cook with it?
Yes — cumin as a food spice in normal cooking amounts is generally safe for most people. The caution is about larger medicinal or supplement doses, where the safety data is limited.
Can cumin cause side effects?
Short-term use is usually well tolerated. The most common side effect is stomach upset. Rarely, people with sensitivities may have allergic reactions, including a serious one called anaphylaxis. Topically, it can cause a rash in sensitive skin.
Will cumin help with my blood sugar or weight?
We don't have strong evidence for it. Animal studies suggest cumin might lower blood sugar, but human research is mixed. The same goes for weight and cholesterol — the evidence is too limited to say it works.
Is it safe to take this while pregnant or breastfeeding?
We don't have enough data to know either way. Talk with your doctor or pharmacist — they can give you personalized advice based on your situation.
Why does cumin interact with so many medications?
The product facts show 211 total medications across its interactions, but that number reflects how broad those three drug categories (blood thinners, diabetes drugs, and one antibiotic) are in practice — not that cumin interacts with hundreds of different molecules. Use the checker to see if any of your specific drugs are affected.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Cumin is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Cumin label
Go deeper

The Full Monographs Behind Cumin’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Cumin

Interacts with 211 drugs

Cumin is a common cooking spice that has a long history in traditional medicine for digestion and other complaints. Food amounts are generally safe for most people, but the evidence for medi...

Read the full Cumin monograph →
Sources

Sources & How We Checked

Cumin's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 10 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Cumin 10 references
  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  2. Anliker, M. D., Borelli, S., and Wuthrich, B. Occupational protein contact dermatitis from spices in a butcher: a new presentation of the mugwort-spice syndrome. Contact Dermatitis 2002;46(2):72-74. PubMed
  3. Dhandapani, S., Subramanian, V. R., Rajagopal, S., and Namasivayam, N. Hypolipidemic effect of Cuminum cyminum L. on alloxan-induced diabetic rats. Pharmacol.Res 2002;46(3):251-255. PubMed
  4. Sachin, B. S., Sharma, S. C., Sethi, S., Tasduq, S. A., Tikoo, M. K., Tikoo, A. K., Satti, N. K., Gupta, B. D., Suri, K. A., Johri, R. K., and Qazi, G. N. Herbal modulation of drug bioavailability: enhancement of rifampicin levels in plasma by herbal pro
  5. Jagtap, A. G. and Patil, P. B. Antihyperglycemic activity and inhibition of advanced glycation end product formation by Cuminum cyminum in streptozotocin induced diabetic rats. Food Chem.Toxicol. 5-6-2010; PubMed
  6. Srivastava, K. C. Extracts from two frequently consumed spices--cumin (Cuminum cyminum) and turmeric (Curcuma longa)--inhibit platelet aggregation and alter eicosanoid biosynthesis in human blood platelets. Prostaglandins Leukot.Essent.Fatty Acids 1989;3 PubMed
  7. Futrell, J. M. and Rietschel, R. L. Spice allergy evaluated by results of patch tests. Cutis 1993;52(5):288-290.
  8. Boxer, M., Roberts, M., and Grammer, L. Cumin anaphylaxis: a case report. J.Allergy Clin.Immunol. 1997;99(5):722-723. PubMed
  9. Karimian J, Farrokhzad A, Jalili C. The effect of cumin (Cuminum cyminum L.) supplementation on glycemic indices: A systematic review and meta-analysis of randomized controlled trials. Phytother Res 2021;35(8):4127-4135.
  10. Tavakoli-Rouzbehani OM, Faghfouri AH, Anbari M, et al. The effects of Cuminum cyminum on glycemic parameters: a systematic review and meta-analysis of controlled clinical trials. J Ethnopharmacol 2021;281:114510. PubMed

See these in context on the Cumin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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