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Dietary supplement

Damiana Ingredients & Drug Interactions

by L.A. Naturals

Damiana label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Damiana against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Damiana is a dietary supplement by L.A. Naturals with 1 active ingredient. Its ingredients are commonly taken for low libido / aphrodisiac, anxiety and stress, mood and mild low energy.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are ethically wild harvested Damiana. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Damiana by L.A. Naturals

Ask about any prescription or over-the-counter medication and we check it for interactions with Damiana by L.A. Naturals — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Damiana by L.A. Naturals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 23, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.

This product is a liquid extract containing one active ingredient: ethically wild harvested damiana. The liquid is made with grain alcohol and deionized water as inactive ingredients.

The damiana leaf has been used traditionally for several purposes, though reliable evidence for many of those uses remains limited.

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: sexual function and arousal.
  • We looked for evidence on: Erectile dysfunction (ED), Sexual dysfunction, libido, desire.
  • The closest evidence on file: Damiana is rated "Insufficient Reliable Evidence To Rate" for Sexual dysfunction (Natural Medicines).
  • Also on file: Damiana is rated "Insufficient Reliable Evidence To Rate" for Erectile dysfunction (ED).

The evidence we hold doesn't establish that damiana works for sexual dysfunction, asthma, headache, cognitive function, constipation, or depression — all six uses carry insufficient evidence ratings. That doesn't mean damiana can't help, just that we don't have solid human trial data to confirm it does.

If you're considering it for one of these reasons, talk it over with your pharmacist to weigh what research does exist outside this database.

The evidence, ingredient by ingredient Damiana

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Damiana is likely well tolerated in small food or tea amounts for most adults, but human safety data overall are limited. The main safety concern comes from a case where a very high dose — 200 grams of damiana extract — caused tetanus-like convulsions and severe symptoms.

Typical doses would be much smaller, but this highlights that more is not always better with herbal extracts. Because safety data in pregnancy and breastfeeding are insufficient, the evidence advises against use during either period.

Side effects, ingredient by ingredient Damiana

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Damiana.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take antidiabetes drugs (insulin, metformin, or other blood sugar medications), you must check your exact medications with the search tool on this page before adding damiana — there's a Moderate risk that it could lower your blood sugar too much.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with insufficient evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Damiana is a traditional herbal extract with limited human safety and effectiveness data. If you take any diabetes medications, you'll need to check with your doctor or pharmacist before starting it, since there's a Moderate risk of blood sugar dropping too low.

Otherwise, chat with your pharmacist about what you're hoping to use it for and whether the current evidence supports that use.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2014.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Damiana, straight from the product label.

Brand L.A. Naturals
Barcode (UPC) 641356039711
Net contents 1 fl. Oz.; 30 mL
Market status On market
Date entered into DSLD Jul 25, 2014
DSLD ID 35018
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Kosher
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Damiana by L.A. Naturals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 mL
Maximum serving Sizes:
2 mL
Servings per container
30
UPC/BARCODE
641356039711
IngredientAmount% DV
ethically wild harvested Damiana0 NP--

Other ingredients: Grain Alcohol, deionized Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

SUGGESTED USE: 30-60 drops in water or juice, 2-3 times daily, or as needed.

Shake well before using.

Precautions

WARNING: Keep out of the reach of children.

General Statements

Plant # K-0001604

MADE IN THE USA

FAST ABSORPTION MEDICINAL BOTANICALS SINGLE HERB IN ALCOHOL

333 mg Herb Weight Equivalence

Herb Strength Ratio 1:3

Seals/Symbols

L.a.(TM)

K PARVE

FDA Statement of Identity

DIETARY SUPPLEMENT

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Damiana by L.A. Naturals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Damiana label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Damiana by L.A. Naturals

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 mL Dosage formLiquid Servings per container30 Amounts shown are per serving.

Ethically wild harvested Damiana

Interacts with
86 drugs
0 NP per serving

Damiana is a traditional herb most famous as an aphrodisiac and mild mood-lifter, but solid human evidence for any of its uses is very limited. It is...

Ethically wild harvested Damiana monograph & interactions

Other (inactive) ingredients: Grain Alcohol, Deionized Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Damiana by L.A. Naturals Drug Interactions

Want to check YOUR meds against Damiana?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

ethically wild harvested Damiana 86

Individual Drug Interactions

The ingredients in Damiana interact with 86 drugs. Click any drug to see the details.

1 of the 1 ingredient in Damiana interact with drugs. Each result below shows which ingredient is responsible. ethically wild harvested Damiana

Each ingredient & the kinds of drugs it affects

For each ingredient in Damiana with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

ethically wild harvested Damiana1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking damiana with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research shows that taking damiana lowers blood glucose level.

Likelihood Possible Evidence D
ethically wild harvested Damiana full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Damiana, from the product label.

L.A. Naturals

See all L.A. Naturals products
Name
Palko Services
Street Address
4991 W. US Hwy 20
City
Michigan City
State
IN
ZipCode
46360
Pharmacist Counseling Corner

Damiana by L.A. Naturals: Common Questions

Does Damiana by L.A. Naturals interact with any medications?
Yes. Based on its ingredients, Damiana has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Damiana contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is damiana safe to take while I'm pregnant or breastfeeding?
No, not according to the safety data. There isn't enough information to know it's safe during either pregnancy or breastfeeding, so it's best to avoid it. Talk with your doctor or pharmacist about what options are available if you're looking for support.
What is damiana actually used for?
Traditionally, damiana has been used for sexual dysfunction, asthma, headache, cognitive function, constipation, and depression. However, we don't have reliable human trial evidence showing it works for any of these uses yet.
Can damiana cause side effects?
In normal amounts, it's likely well tolerated. The main safety signal comes from a case where someone took a very large dose (200 grams of extract) and experienced severe convulsions and seizure-like symptoms. Human safety data are limited overall, so more research is needed.
How much damiana is safe to take?
The facts show damiana is likely fine in food or tea amounts for most adults, but larger supplement doses haven't been well studied in humans. Ask your pharmacist what dose is appropriate for what you're hoping to achieve.
Does damiana interact with my medications?
If you take diabetes medications, there's a moderate risk that damiana could lower your blood sugar too much. Use the search tool on this page to check your exact medications, and run the results past your doctor or pharmacist.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Damiana is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Damiana label
Go deeper

The Full Monographs Behind Damiana’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Damiana

Interacts with 86 drugs

Damiana is a traditional herb most famous as an aphrodisiac and mild mood-lifter, but solid human evidence for any of its uses is very limited. It is generally well tolerated in the small am...

Read the full Damiana monograph →
Sources

Sources & How We Checked

Damiana's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Damiana 2 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Alarcon-Aquilar FJ, Roman-Ramos R, Perez-Gutierrez S, et al. Study of the anti-hyperglycemic effect of plants used as antidiabetics. J Ethnopharmacol 1998;61:101-10. PubMed

See these in context on the Damiana monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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