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Dietary supplement

Damiana Extract 400 mg Ingredients & Drug Interactions

by BulkSupplements.com

Damiana Extract 400 mg label
See full label image
Powder Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Damiana Extract 400 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Damiana Extract 400 mg is a dietary supplement by BulkSupplements.com with 1 active ingredient. Its ingredients are commonly taken for low libido / aphrodisiac, anxiety and stress, mood and mild low energy.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Damiana Leaf Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Damiana Extract 400 mg by BulkSupplements.com

Ask about any prescription or over-the-counter medication and we check it for interactions with Damiana Extract 400 mg by BulkSupplements.com — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Damiana Extract 400 mg by BulkSupplements.com

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: damiana leaf extract at 400 mg per serving. Damiana is an herbal extract traditionally used for various purposes, though the scientific evidence for most of those uses is not yet established.

The powder also contains dextrin, an inactive ingredient used as a carrier.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Damiana product and its label doesn't state a use — see Damiana's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence we hold rates damiana's effectiveness for sexual dysfunction, asthma, headache, cognitive function, constipation, and depression all as insufficient to make a reliable rating. In plain terms, there isn't enough solid research yet to say whether damiana actually works for any of these.

The evidence, ingredient by ingredient Damiana

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Damiana is likely well tolerated in small amounts—the kind you'd get in food or tea—but human safety data are limited, so we don't have a lot of real-world information on how safe it is at higher doses. One report documented a person who took a very large amount (200 grams of extract) and experienced severe muscle contractions and spasm-like symptoms.

There isn't enough data to know whether damiana is safe during pregnancy or while breastfeeding, so both are best avoided unless you've talked it over with your doctor or pharmacist.

Side effects, ingredient by ingredient Damiana

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Damiana.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take antidiabetes medications—insulin, metformin, or any drug to lower blood sugar—check with your pharmacist before starting this product. Damiana may increase the risk of low blood sugar (hypoglycemia).

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you're curious about damiana for general wellness, the limited data suggest it's probably okay at typical supplement doses. But if you take medication for diabetes, you need to check with your pharmacist first—this product could lower your blood sugar too much.

There's also not enough safety information for pregnancy or breastfeeding, so talk to your doctor if either applies to you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 24, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Damiana Extract 400 mg, straight from the product label.

Brand BulkSupplements.com
Barcode (UPC) X002KUNF3N
Net contents 1 Kilogram(s); 35.3 Ounce(s)
Market status On market
Date entered into DSLD Apr 24, 2025
DSLD ID 330782
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Damiana Extract 400 mg by BulkSupplements.com, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
400 Milligram(s)
Maximum serving Sizes:
400 Milligram(s)
Servings per container
2500
UPC/BARCODE
X002KUNF3N
IngredientAmount% DV
Damiana Leaf Extract400 mg--

Other ingredients: Dextrin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Damiana Extract 400 mg per serving

Brand IP Statement(s)

Bulksupplements.com Clean & Pure Bulk Supplements

Formulation

Color may vary

Free of: Added sugar, soy, dairy, yeast, gluten

FDA Disclaimer Statement

Warning: This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Always consult a physician before taking any dietary supplement.

Keep out of reach of children.

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take 400 mg (about 1/5 tsp) once or twice daily, or as directed by a physician.

Storage

Contents are sold by weight, not volume. Settling may occur. Store in a dry, cool place

General Statements

New Use an accurate milligram scale.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Damiana Extract 400 mg by BulkSupplements.com label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Damiana Extract 400 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Damiana Extract 400 mg by BulkSupplements.com

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size400 Milligram(s) Dosage formPowder Servings per container2500 Amounts shown are per serving.

Damiana Leaf Extract

Interacts with
86 drugs
400 mg per serving

Damiana is a traditional herb most famous as an aphrodisiac and mild mood-lifter, but solid human evidence for any of its uses is very limited. It is...

Damiana Leaf Extract monograph & interactions

Other (inactive) ingredients: Dextrin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Damiana Extract 400 mg by BulkSupplements.com Drug Interactions

Want to check YOUR meds against Damiana Extract 400 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Damiana Leaf Extract 86

Individual Drug Interactions

The ingredients in Damiana Extract 400 mg interact with 86 drugs. Click any drug to see the details.

1 of the 1 ingredient in Damiana Extract 400 mg interact with drugs. Each result below shows which ingredient is responsible. Damiana Leaf Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Damiana Extract 400 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Damiana Leaf Extract1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking damiana with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research shows that taking damiana lowers blood glucose level.

Likelihood Possible Evidence D
Damiana Leaf Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Damiana Extract 400 mg, from the product label.

BulkSupplements.com

See all BulkSupplements.com products
Name
BulkSupplements.com
Street Address
7511 Eastgate Rd
City
Henderson
State
NV
ZipCode
89011
Web Address
BulkSupplements.com
Pharmacist Counseling Corner

Damiana Extract 400 mg by BulkSupplements.com: Common Questions

Does Damiana Extract 400 mg by BulkSupplements.com interact with any medications?
Yes. Based on its ingredients, Damiana Extract 400 mg has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Damiana Extract 400 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take damiana if I'm pregnant or breastfeeding?
There isn't enough safety data to know either way. Both pregnancy and breastfeeding are best avoided with damiana unless you've talked it over with your doctor or pharmacist. They can help you decide based on your individual situation.
What is damiana used for?
Damiana has been used traditionally for a number of purposes—sexual dysfunction, asthma, headache, cognitive function, constipation, and depression among them. However, we don't have reliable evidence yet that it actually works for any of these.
Are there any side effects I should know about?
Damiana is likely well tolerated in typical supplement amounts, though human safety data are limited. One case report documented severe muscle spasms and contractions from an extremely high dose (200 grams of extract), but that's far above what you'd get in a normal supplement.
What's in this powder besides damiana?
The active ingredient is damiana leaf extract at 400 mg per serving. The only other ingredient is dextrin, an inactive carrier used to make the powder.
I take diabetes medication. Is this safe for me?
No—check with your pharmacist first. Damiana may lower blood sugar on its own, so taking it with antidiabetes medication could raise your risk of low blood sugar. Your pharmacist can help you decide whether it's right for your specific medications.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Damiana Extract 400 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Damiana Extract 400 mg label
Go deeper

The Full Monographs Behind Damiana Extract 400 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Damiana

Interacts with 86 drugs

Damiana is a traditional herb most famous as an aphrodisiac and mild mood-lifter, but solid human evidence for any of its uses is very limited. It is generally well tolerated in the small am...

Read the full Damiana monograph →
Sources

Sources & How We Checked

Damiana Extract 400 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Damiana 2 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Alarcon-Aquilar FJ, Roman-Ramos R, Perez-Gutierrez S, et al. Study of the anti-hyperglycemic effect of plants used as antidiabetics. J Ethnopharmacol 1998;61:101-10. PubMed

See these in context on the Damiana monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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