Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Damiana Leaf Ingredients & Drug Interactions

by Herb Stop

Damiana Leaf label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Damiana Leaf against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Damiana Leaf is a dietary supplement by Herb Stop with 1 active ingredient. Its ingredients are commonly taken for low libido / aphrodisiac, anxiety and stress, mood and mild low energy.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Damiana. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Damiana Leaf by Herb Stop

Ask about any prescription or over-the-counter medication and we check it for interactions with Damiana Leaf by Herb Stop — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Damiana Leaf by Herb Stop

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 23, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Damiana Leaf by Herb Stop contains one active ingredient: damiana (also called Turnera diffusa), a plant leaf traditionally used in herbal medicine. The capsule itself is made from hydroxypropyl methylcellulose, a plant-based capsule material, with purified water.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Damiana's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Normalizes arousal and desire.
  • We looked for evidence on: Sexual dysfunction, Erectile dysfunction (ED), Libido, Sexual health.
  • The closest evidence on file: Damiana is rated "Insufficient Reliable Evidence To Rate" for Sexual dysfunction (Natural Medicines).
  • Also on file: Damiana is rated "Insufficient Reliable Evidence To Rate" for Erectile dysfunction (ED).

The evidence for damiana isn't established in the data we hold. Our effectiveness ratings show insufficient reliable evidence to rate it for sexual dysfunction, asthma, headache, cognitive function, constipation, and depression — meaning the clinical trials we have access to don't support a clear conclusion either way for any of these uses.

If you're considering it for one of these reasons, talk it over with your doctor or pharmacist about what the best option might be for you.

The evidence, ingredient by ingredient Damiana

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Human safety data for damiana are limited, so we advise caution — it's generally well tolerated in the amounts you'd get from food or tea, but we don't have robust long-term studies. You should avoid damiana during pregnancy and while breastfeeding; the safety data aren't there to say it's okay.

At very high doses (200 grams of damiana extract), serious effects have been reported in human cases, including tetanus-like convulsions and severe neurological symptoms — this is well above typical supplement doses, but it's worth knowing.

Side effects, ingredient by ingredient Damiana

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Damiana.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take antidiabetes drugs — insulin, metformin, sulfonylureas, or others — check with your doctor or pharmacist before you start damiana. The moderate interaction risk is a lower blood sugar level, which may need monitoring or a change to your medication dose.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Damiana Leaf is a single-ingredient supplement with limited human safety data and no established evidence for the conditions it's traditionally used for. If you take any diabetes medication, you'll need to check with your doctor or pharmacist before starting it, because of the moderate risk of low blood sugar.

Pregnant or nursing women should avoid it. It's a good idea to talk through whether this is the right choice for you with your own healthcare provider.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Damiana Leaf, straight from the product label.

Brand Herb Stop
Net contents 300 Veggie Capsule(s)
Market status On market
Date entered into DSLD Sep 25, 2023
DSLD ID 297288
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Women (not pregnant or lactating), Organic, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Damiana Leaf by Herb Stop, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
150
IngredientAmount% DV
Damiana560 mg--

Other ingredients: Hydroxypropyl Methylcellulose, Water, Purified

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: Take 2 capsules 1 to 3 times per day with water, or as directed by your qualified healthcare professional.

Precautions

Safety Guideline: Not to be used during pregnancy or lactation. If you have a medical condition or take pharmaceutical drugs, please consult with your doctor before use.

Keep away from children.

Use only as directed on label.

Brand IP Statement(s)

Herb Stop Health In Your Own Hands

Formula

Herbal Capsule

Formulation

Certified Organic

Normalizes arousal and desire

Vegan & Cruelty-Free

Cruelty-Free Made in the USA.

FDA Statement of Identity

Dietary Supplement

General Statements

Certified Organic

Lot #1605825

FDA Disclaimer Statement

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Damiana Leaf by Herb Stop label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Damiana Leaf label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Damiana Leaf by Herb Stop

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container150 Amounts shown are per serving.

Damiana

Interacts with
86 drugs
560 mg per serving Form: Turnera aphrodisaca

Damiana is a traditional herb most famous as an aphrodisiac and mild mood-lifter, but solid human evidence for any of its uses is very limited. It is...

Damiana monograph & interactions

Other (inactive) ingredients: Hydroxypropyl Methylcellulose, Water, Purified. These complete the product’s ingredient list but are not active constituents.

Interaction report

Damiana Leaf by Herb Stop Drug Interactions

Want to check YOUR meds against Damiana Leaf?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Damiana 86

Individual Drug Interactions

The ingredients in Damiana Leaf interact with 86 drugs. Click any drug to see the details.

1 of the 1 ingredient in Damiana Leaf interact with drugs. Each result below shows which ingredient is responsible. Damiana

Each ingredient & the kinds of drugs it affects

For each ingredient in Damiana Leaf with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Damiana1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking damiana with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research shows that taking damiana lowers blood glucose level.

Likelihood Possible Evidence D
Damiana full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Damiana Leaf, from the product label.

Herb Stop

See all Herb Stop products
Name
The Herb Stop
Street Address
PO Box 673
City
Pine
State
AZ
ZipCode
85544
Phone Number
877.345.4372
Web Address
www.herbstop.com
Pharmacist Counseling Corner

Damiana Leaf by Herb Stop: Common Questions

Does Damiana Leaf by Herb Stop interact with any medications?
Yes. Based on its ingredients, Damiana Leaf has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Damiana Leaf contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Damiana Leaf if I'm pregnant or breastfeeding?
No — the safety data aren't there, so it's advised against during both pregnancy and breastfeeding. Talk to your doctor or pharmacist if you're thinking about it.
Does damiana actually work for sexual dysfunction?
The evidence isn't established in our data — there's insufficient reliable evidence to rate it for sexual dysfunction or the other uses it's traditionally claimed to treat. You may want to discuss other options with your doctor.
What are the side effects of damiana?
Human safety data are limited. At typical supplement doses it's generally well tolerated, but very high doses (200 grams of extract) have caused severe neurological symptoms like tetanus-like convulsions in rare cases. Stick to the label dose.
Is there a filler in this capsule?
The capsule itself is made from hydroxypropyl methylcellulose, a plant-based material, along with purified water. There are no additional fillers listed.
What exactly is damiana?
Damiana is a plant leaf, also called Turnera diffusa, traditionally used in herbal medicine. It's the only active ingredient in this product.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Damiana Leaf is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Damiana Leaf label
Go deeper

The Full Monographs Behind Damiana Leaf’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Damiana

Interacts with 86 drugs

Damiana is a traditional herb most famous as an aphrodisiac and mild mood-lifter, but solid human evidence for any of its uses is very limited. It is generally well tolerated in the small am...

Read the full Damiana monograph →
Sources

Sources & How We Checked

Damiana Leaf's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Damiana 2 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Alarcon-Aquilar FJ, Roman-Ramos R, Perez-Gutierrez S, et al. Study of the anti-hyperglycemic effect of plants used as antidiabetics. J Ethnopharmacol 1998;61:101-10. PubMed

See these in context on the Damiana monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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