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Dietary supplement

DMAE 2-Dimethylaminoethanol Bitartrate Ingredients & Drug Interactions

by OL Olympian Labs Incorporated

Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Minor
The interaction bottom line Most serious interaction: Minor

DMAE 2-Dimethylaminoethanol Bitartrate is a dietary supplement by OL Olympian Labs Incorporated with 1 active ingredient. Its ingredients are commonly taken for memory and focus, mood and mental clarity, adhd-type symptoms.Based on those ingredients, 219 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are DMAE. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of DMAE 2-Dimethylaminoethanol Bitartrate by OL Olympian Labs Incorporated

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: DMAE (2-dimethylaminoethanol bitartrate), a compound thought to support acetylcholine, a chemical messenger in the brain. The remaining ingredients—microcrystalline cellulose, rice flour, ascorbyl palmitate, and silica—are inactive excipients used to form the capsule and improve shelf life.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Deanol's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: memory and focus, brain health.
  • We looked for evidence on: Cognitive function, Attention deficit-hyperactivity disorder (ADHD), Alzheimer disease, mental clarity, ADHD-type symptoms.
  • The closest evidence on file: Deanol is rated "Likely Ineffective" for Alzheimer disease (Natural Medicines).
  • Also on file: Deanol is rated "Insufficient Reliable Evidence To Rate" for Attention deficit-hyperactivity disorder (ADHD), Cognitive function.

The evidence for DMAE is limited. It is rated likely ineffective for Alzheimer disease and tardive dyskinesia (a movement disorder).

For aging skin, ADHD, and athletic performance, the evidence isn't established well enough in our data to say whether it works or not.

The evidence, ingredient by ingredient Deanol

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

DMAE is generally well tolerated by mouth, but side effects can happen. The most common ones reported are abdominal cramps, abdominal pain, diarrhea, drowsiness, nausea, and vomiting.

Other reported effects include constipation, headache, insomnia, overstimulation, confusion, and mood changes. At higher doses (over 1000 mg daily), mood changes including depression and hypomania have been reported, and in people with schizophrenia, it has been linked to worsening symptoms.

The safety data advises against DMAE during pregnancy. There isn't enough data to know whether it's safe during breastfeeding—talk with your doctor or pharmacist before using it if you're breastfeeding.

Side effects, ingredient by ingredient Deanol

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Deanol.
  • The most serious interaction on file is rated Minor.
  • For scale: 219 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking DMAE, check with your doctor or pharmacist if you take anticholinergic drugs (used for urinary or bowel issues, motion sickness, or certain eye conditions) or cholinergic drugs (like those for myasthenia gravis or some types of glaucoma). Both categories have Minor interactions with DMAE.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Only minor medication interactions are documented, and safety information is well characterized.

DMAE may appeal to someone curious about brain health, but the evidence for most of its claimed uses isn't solid, and it does carry Minor interactions with common medication types. If you take anticholinergic or cholinergic drugs, you'll want to check your exact medications with your doctor or pharmacist before starting.

If you're pregnant or breastfeeding, the safety data suggests avoiding it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2012.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about DMAE 2-Dimethylaminoethanol Bitartrate, straight from the product label.

Brand OL Olympian Labs Incorporated
Barcode (UPC) 710013003324
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Jun 25, 2012
DSLD ID 9526
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for DMAE 2-Dimethylaminoethanol Bitartrate by OL Olympian Labs Incorporated, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
710013003324
IngredientAmount% DV
DMAE100 mg--

Other ingredients: Microcrystalline Cellulose, Rice Flour, Ascorbyl Palmitate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

SUGGESTED USE: As a dietary supplement,take one (1) capsule before a meal, or as directed by a healthcare professional.

Seals/Symbols

Since 1992 OL

VEGETARIAN & KOSHER CAPSULES V

General Statements

OLYMPIAN LABS PRESIDENT'S GUARANTEE: I guarantee that all Olympian Labs products are of the highest quality ingredients and lab assayed to ensure that what we say is on the label is actually in the product.

When you buy an Olympian Labs product, you can be sure you are buying the best.

Confused on what to take? Check yourself at: WhatVitaminsAreRightForYou.com

Made in USA

Formulation

All Olympian Labs products are free from most allergens such as corn, yeast, barley, gluten, wheat, soy, lactose, all milk products, citrus, fish and egg products, as well as added flavorings, sugars, sweeteners, salt, preservatives, salicylates, and artificial colors.

Vegetarian Safe

Precautions

KEEP OUT OF REACH OF CHILDREN.

Storage

STORE IN A COOL, DRY PLACE.

FDA Statement of Identity

Dietary Supplement

See for yourself

DMAE 2-Dimethylaminoethanol Bitartrate by OL Olympian Labs Incorporated label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in DMAE 2-Dimethylaminoethanol Bitartrate by OL Olympian Labs Incorporated

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

DMAE

Interacts with
219 drugs
100 mg per serving Form: 2-Dimethylaminoethanol Bitartrate

Deanol (DMAE) is a compound related to choline that is marketed for memory, focus, and mood, but solid human evidence for most of these uses is limite...

DMAE monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Rice Flour, Ascorbyl Palmitate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

DMAE 2-Dimethylaminoethanol Bitartrate by OL Olympian Labs Incorporated Drug Interactions

Want to check YOUR meds against DMAE 2-Dimethylaminoethanol Bitartrate?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
219Drugs
219 Minor

Ingredients driving the most interactions

DMAE 219

Each ingredient & the kinds of drugs it affects

For each ingredient in DMAE 2-Dimethylaminoethanol Bitartrate with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

DMAE2 drug types · 219 drugs

Anticholinergic Drugs

Theoretically, deanol might decrease the effectiveness of anticholinergic drugs.
Deanol is thought to increase acetylcholine levels.

Likelihood Unlikely Evidence D
Cholinergic Drugs

Theoretically, deanol might increase the effects and adverse effects of cholinergic drugs.
Deanol is thought to increase acetylcholine levels.

Likelihood Unlikely Evidence D
The maker

Brand information

Manufacturer and brand details for DMAE 2-Dimethylaminoethanol Bitartrate, from the product label.

OL Olympian Labs Incorporated

See all OL Olympian Labs Incorporated products
Name
OLYMPIAN LABS INCORPORATED
Street Address
P.O. Box 12461
City
Scottsdale
State
AZ
ZipCode
85267
Phone Number
1-800-473-5883
Web Address
www.OlympianLabs.com
Pharmacist Counseling Corner

DMAE 2-Dimethylaminoethanol Bitartrate by OL Olympian Labs Incorporated: Common Questions

Does DMAE 2-Dimethylaminoethanol Bitartrate by OL Olympian Labs Incorporated interact with any medications?
Yes. Based on its ingredients, DMAE 2-Dimethylaminoethanol Bitartrate has a known interaction with 219 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
DMAE 2-Dimethylaminoethanol Bitartrate contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is DMAE supposed to do?
DMAE is thought to increase a brain chemical called acetylcholine, which plays a role in memory and thinking. However, the evidence that it actually helps with Alzheimer disease, ADHD, or aging skin is limited or not established.
What are the most common side effects?
The most frequently reported side effects are abdominal cramps and pain, diarrhea, drowsiness, nausea, and vomiting. Most people tolerate it, but side effects can occur.
Can I take DMAE if I'm pregnant or breastfeeding?
The safety data advises against DMAE during pregnancy. If you're breastfeeding, there isn't enough data to know either way—talk with your doctor or pharmacist for personalized advice before using it.
Does DMAE interact with my medications?
DMAE has theoretical Minor interactions with anticholinergic and cholinergic drugs. It may weaken anticholinergic drugs or strengthen the effects of cholinergic drugs. Use the checker on this page to look up your specific medications, or ask your doctor or pharmacist.
Are there any inactive fillers in this product?
Yes, the capsule contains microcrystalline cellulose, rice flour, ascorbyl palmitate, and silica as inactive ingredients to form and preserve the supplement.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if DMAE 2-Dimethylaminoethanol Bitartrate is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

DMAE 2-Dimethylaminoethanol Bitartrate label
Go deeper

The Full Monographs Behind DMAE 2-Dimethylaminoethanol Bitartrate’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

DMAE 2-Dimethylaminoethanol Bitartrate's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 15 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Deanol 15 references
  1. Davies C, Maidment S, Hanley P, et al. Dimethylaminoethanol (DMAE). HSE. Risk assessment document; EH72/2;1997. (TOXLINE).
  2. Re O. 2-Dimethylaminoethanol (deanol): a brief review of its clinical efficacy and postulated mechanism of action. Curr Ther Res Clin Exp 1974;16:1238-42.
  3. Pieralisi G, Ripari P, Vecchiet L. Effects of a standardized ginseng extract combined with dimethylaminoethanol bitartrate, vitamins, minerals, and trace elements on physical performance during exercise. Clin Ther 1991;13:373-82.
  4. George J, Pridmore S, Aldous D. Double blind controlled trial of deanol in tardive dyskinesia. Aust N Z J Psychiatry 1981;15:68-71. PubMed
  5. Penovich P, Morgan JP, Kerzner B, et al. Double-blind evaluation of deanol in tardive dyskinesia. JAMA 1978;239:1997-8. DOI
  6. de Montigny C, Chouinard G, Annable L. Ineffectiveness of deanol in tardive dyskinesia: a placebo controlled study. Psychopharmacology (Berl) 1979;65:219-23. PubMed
  7. Lindeboom SF, Lakke JP. Deanol and physostigmine in the treatment of L-dopa-induced dyskinesias. Acta Neurol Scand 1978;58:134-8. PubMed
  8. Jus A, Villeneuve A, Gautier J, et al. Deanol, lithium and placebo in the treatment of tardive dyskinesia. A double-blind crossover study. Neuropsychobiology 1978;4:140-9. PubMed
  9. Lewis JA, Young R. Deanol and methylphenidate in minimal brain dysfunction. Clin Pharmacol Ther 1975;17:534-40. PubMed
  10. Fisman M, Mersky H, Helmes E. Double-blind trial of 2-dimethylaminoethanol in Alzheimer's disease. Am J Psychiatry 1981;138:970-2. PubMed
  11. Ferris SH, Sathananthan G, Gershon S, et al. Senile dementia: treatment with deanol. J Am Geriatr Soc 1977;25:241-4. PubMed
  12. Haug BA, Holzgraefe M. Orofacial and respiratory tardive dyskinesia: potential side effects of 2-dimethylaminoethanol (deanol)? Eur Neurol 1991;31:423-5. PubMed
  13. Casey DE. Mood alterations during deanol therapy. Psychopharmacology (Berl) 1979;62:187-91. PubMed
  14. Sergio W. Use of DMAE (2-dimethylaminoethanol) in the induction of lucid dreams. Med Hypotheses 1988;26:255-7. PubMed
  15. Osol A, Hoover JE, eds. Remington's Pharmaceutical Science, 15th ed. Easton, PA: Mack Publishing Company, 1975.

See these in context on the Deanol monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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