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Dietary supplement

DMAE Bitartrate 150 mg Ingredients & Drug Interactions

by Life Extension

Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Minor
The interaction bottom line Most serious interaction: Minor

DMAE Bitartrate 150 mg is a dietary supplement by Life Extension with 1 active ingredient. Its ingredients are commonly taken for memory and focus, mood and mental clarity, adhd-type symptoms.Based on those ingredients, 219 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Dimethylaminoethanol. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of DMAE Bitartrate 150 mg by Life Extension

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: dimethylaminoethanol (deanol), supplied at 150 mg per capsule. The supplement also includes microcrystalline cellulose, cellulose, and stearate as inactive ingredients to form and fill the capsule.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Deanol's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: memory, focus, and brain health.
  • We looked for evidence on: Cognitive function, Attention deficit-hyperactivity disorder (ADHD), Alzheimer disease, mental clarity, mood support, neurotransmitter synthesis.
  • The closest evidence on file: Deanol is rated "Likely Ineffective" for Alzheimer disease (Natural Medicines).
  • Also on file: Deanol is rated "Insufficient Reliable Evidence To Rate" for Attention deficit-hyperactivity disorder (ADHD), Cognitive function.

The evidence for deanol is limited. For Alzheimer disease and tardive dyskinesia (involuntary movement disorder), studies rate it likely ineffective.

For aging skin, ADHD, and athletic performance, there isn't enough reliable evidence to establish whether it works.

The evidence, ingredient by ingredient Deanol

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Deanol seems to be well tolerated by some adults, but the safety data is limited and side effects do occur. Common side effects include abdominal cramps, abdominal pain, diarrhea, drowsiness, nausea, and vomiting.

At higher doses — over 1000 mg daily — it has been reported to cause mood changes like depression and hypomania, particularly in people with psychiatric conditions. Doses of 1500 mg daily have been reported to increase schizophrenic symptoms in patients with chronic schizophrenia.

The safety data isn't sufficient during pregnancy, so it's best avoided then. There isn't enough safety information for breastfeeding, so it's also best avoided while nursing.

Side effects, ingredient by ingredient Deanol

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Deanol.
  • The most serious interaction on file is rated Minor.
  • For scale: 219 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your exact medications if you take anticholinergic drugs (like those for overactive bladder or certain motion sickness remedies) or cholinergic drugs (such as those for myasthenia gravis or certain types of glaucoma) — deanol may affect how they work. Both interactions are minor, but worth verifying with the search tool on this page.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Only minor medication interactions are documented, and safety information is well characterized.

Deanol (DMAE) is one to check before you start, especially if you take anticholinergic or cholinergic medications. The evidence for its effectiveness is weak to absent for most conditions.

If you take any prescription medications or have a psychiatric condition, talk with your pharmacist before using this product.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 21, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about DMAE Bitartrate 150 mg, straight from the product label.

Brand Life Extension
Barcode (UPC) 737870154020
Net contents 200 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD May 21, 2025
DSLD ID 328416
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for DMAE Bitartrate 150 mg by Life Extension, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Vegetarian Capsule(s)
Maximum serving Sizes:
1 Vegetarian Capsule(s)
Servings per container
200
UPC/BARCODE
737870154020
IngredientAmount% DV
Dimethylaminoethanol150 mg--

Other ingredients: Microcrystalline Cellulose, Cellulose, Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Scan for product info

Precautions

Read the entire label and follow the directions carefully prior to use.

Caution: If excitation, restlessness, muscle tension, or headache occurs, reduce dosage or discontinue use.

Warnings: Keep out of reach of children.

Do not exceed recommended dose. Do not purchase if outer seal is broken or damaged.

When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

To report a serious adverse event or obtain product information, contact 1-866-280-2852.

Suggested/Recommended/Usage/Directions

Directions: Take one (1) capsule daily, or as recommended by a healthcare practitioner. This product is best utilized if taken early in the day on an empty stomach.

Storage

Store tightly closed in a cool, dry place.

Formulation

Gluten free Non GMO LE certified

Stimulates cognitive function

Seals/Symbols

Non GMO LE Certified

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

See for yourself

DMAE Bitartrate 150 mg by Life Extension label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in DMAE Bitartrate 150 mg by Life Extension

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Vegetarian Capsule(s) Dosage formCapsule Servings per container200 Amounts shown are per serving.

Dimethylaminoethanol

Interacts with
219 drugs
150 mg per serving Form: Dimethylaminoethanol Bitartrate

Deanol (DMAE) is a compound related to choline that is marketed for memory, focus, and mood, but solid human evidence for most of these uses is limite...

Dimethylaminoethanol monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Cellulose, Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

DMAE Bitartrate 150 mg by Life Extension Drug Interactions

Want to check YOUR meds against DMAE Bitartrate 150 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
219Drugs
219 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in DMAE Bitartrate 150 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Dimethylaminoethanol2 drug types · 219 drugs

Anticholinergic Drugs

Theoretically, deanol might decrease the effectiveness of anticholinergic drugs.
Deanol is thought to increase acetylcholine levels.

Likelihood Unlikely Evidence D
Cholinergic Drugs

Theoretically, deanol might increase the effects and adverse effects of cholinergic drugs.
Deanol is thought to increase acetylcholine levels.

Likelihood Unlikely Evidence D
The maker

Brand information

Manufacturer and brand details for DMAE Bitartrate 150 mg, from the product label.

Life Extension

See all Life Extension products
Name
Quality Supplements and Vitamins, Inc.
City
Ft. Lauderdale
State
FL
ZipCode
33309
Phone Number
1-866-280-2852
Web Address
LifeExtension.com
Pharmacist Counseling Corner

DMAE Bitartrate 150 mg by Life Extension: Common Questions

Does DMAE Bitartrate 150 mg by Life Extension interact with any medications?
Yes. Based on its ingredients, DMAE Bitartrate 150 mg has a known interaction with 219 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
DMAE Bitartrate 150 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is DMAE, and what is it supposed to do?
DMAE is dimethylaminoethanol, a compound thought to increase acetylcholine levels in the brain. It's been studied for conditions like Alzheimer disease, ADHD, and aging skin, but the evidence that it works is either weak or lacking.
Can I take this if I'm pregnant or breastfeeding?
No, there isn't enough safety data to know either way during pregnancy or breastfeeding, so it's best avoided in both cases. Talk with your doctor or pharmacist for personalized advice.
What side effects might I experience?
The most common ones are abdominal cramps, abdominal pain, diarrhea, drowsiness, nausea, and vomiting. At higher doses, mood changes and, in people with schizophrenia, worsening symptoms have been reported.
Does this product have fillers?
Yes, the capsule contains microcrystalline cellulose, cellulose, and stearate as inactive ingredients.
How much DMAE is in each capsule?
Each capsule contains 150 mg of dimethylaminoethanol (deanol).

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if DMAE Bitartrate 150 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

DMAE Bitartrate 150 mg label
Go deeper

The Full Monographs Behind DMAE Bitartrate 150 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

DMAE Bitartrate 150 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 15 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Deanol 15 references
  1. Davies C, Maidment S, Hanley P, et al. Dimethylaminoethanol (DMAE). HSE. Risk assessment document; EH72/2;1997. (TOXLINE).
  2. Re O. 2-Dimethylaminoethanol (deanol): a brief review of its clinical efficacy and postulated mechanism of action. Curr Ther Res Clin Exp 1974;16:1238-42.
  3. Pieralisi G, Ripari P, Vecchiet L. Effects of a standardized ginseng extract combined with dimethylaminoethanol bitartrate, vitamins, minerals, and trace elements on physical performance during exercise. Clin Ther 1991;13:373-82.
  4. George J, Pridmore S, Aldous D. Double blind controlled trial of deanol in tardive dyskinesia. Aust N Z J Psychiatry 1981;15:68-71. PubMed
  5. Penovich P, Morgan JP, Kerzner B, et al. Double-blind evaluation of deanol in tardive dyskinesia. JAMA 1978;239:1997-8. DOI
  6. de Montigny C, Chouinard G, Annable L. Ineffectiveness of deanol in tardive dyskinesia: a placebo controlled study. Psychopharmacology (Berl) 1979;65:219-23. PubMed
  7. Lindeboom SF, Lakke JP. Deanol and physostigmine in the treatment of L-dopa-induced dyskinesias. Acta Neurol Scand 1978;58:134-8. PubMed
  8. Jus A, Villeneuve A, Gautier J, et al. Deanol, lithium and placebo in the treatment of tardive dyskinesia. A double-blind crossover study. Neuropsychobiology 1978;4:140-9. PubMed
  9. Lewis JA, Young R. Deanol and methylphenidate in minimal brain dysfunction. Clin Pharmacol Ther 1975;17:534-40. PubMed
  10. Fisman M, Mersky H, Helmes E. Double-blind trial of 2-dimethylaminoethanol in Alzheimer's disease. Am J Psychiatry 1981;138:970-2. PubMed
  11. Ferris SH, Sathananthan G, Gershon S, et al. Senile dementia: treatment with deanol. J Am Geriatr Soc 1977;25:241-4. PubMed
  12. Haug BA, Holzgraefe M. Orofacial and respiratory tardive dyskinesia: potential side effects of 2-dimethylaminoethanol (deanol)? Eur Neurol 1991;31:423-5. PubMed
  13. Casey DE. Mood alterations during deanol therapy. Psychopharmacology (Berl) 1979;62:187-91. PubMed
  14. Sergio W. Use of DMAE (2-dimethylaminoethanol) in the induction of lucid dreams. Med Hypotheses 1988;26:255-7. PubMed
  15. Osol A, Hoover JE, eds. Remington's Pharmaceutical Science, 15th ed. Easton, PA: Mack Publishing Company, 1975.

See these in context on the Deanol monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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