Interactions on record — worth a quick check against your medications. Based on 5 of 6 ingredients. Check your meds →
Dietary supplement

Fiber Sugar-Free Prebiotic Gummies Ingredients & Drug Interactions

by Atlantis Nutrition

Fiber Sugar-Free Prebiotic Gummies label
See full label image
Gummy Or Jelly Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Fiber Sugar-Free Prebiotic Gummies against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Fiber Sugar-Free Prebiotic Gummies is a dietary supplement by Atlantis Nutrition with 6 active ingredients. Its ingredients are commonly taken for replacing fluids and electrolytes, preventing dehydration during exercise or illness, treating low blood sodium (under medical care).Based on those ingredients, 2,041 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Dietary Fiber, Agar Agar, Sodium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Fiber Sugar-Free Prebiotic Gummies by Atlantis Nutrition

Ask about any prescription or over-the-counter medication and we check it for interactions with Fiber Sugar-Free Prebiotic Gummies by Atlantis Nutrition — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Fiber Sugar-Free Prebiotic Gummies by Atlantis Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 2 of its 6 active ingredients.
  • “PreBiotic Digestive Blend” is a proprietary blend — the label gives one combined amount (5.40 Gram(s)) without saying how much of each component you get.

Fiber Sugar-Free Prebiotic Gummies contains 5 active ingredients. Sodium is an electrolyte that helps your body maintain fluid balance and nerve function, though excess amounts can strain your heart and raise blood pressure.

Fructooligosaccharides and isomaltooligosaccharides are types of soluble fiber that feed beneficial bacteria in your gut (that's what "prebiotic" means). Pectin is a natural fiber from fruit that helps thicken the gummy and may support cholesterol levels.

Agar agar is a fiber derived from seaweed that gives the gummy its gel structure. The product also contains inactive ingredients (fillers and binders) including water, citric acid, black carrot concentrate, chlorophyll, trisodium citrate, and carnauba wax.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: support digestive health with prebiotic fiber.
  • We looked for evidence on: Constipation, Diarrhea, Irritable bowel syndrome (IBS), Travelers' diarrhea, gut microbiome balance, dysbiosis.
  • The strongest evidence on file: Black Psyllium is rated "Effective" for Constipation (Natural Medicines).
  • Also on file: Black Psyllium is rated "Insufficient Reliable Evidence To Rate" for Diarrhea.
  • Also on file: Fructo-oligosaccharides (fos) is rated "Insufficient Reliable Evidence To Rate" for Constipation, Travelers' diarrhea.

The evidence for this product's ingredients is limited. Pectin has possibly effective evidence for lowering cholesterol.

Sodium, fructooligosaccharides, agar, and isomaltooligosaccharides do not have established evidence for the conditions they're used to treat in our data — we hold insufficient or no reliable evidence to rate them.

The evidence, ingredient by ingredient Sodium Black Psyllium Fructo-oligosaccharides (fos) Agar Pectin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 5 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 5 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

These gummies are generally well tolerated in moderate amounts. Sodium is essential in small quantities, but too much is linked to high blood pressure and heart strain — normal dietary sodium is fine, but avoid sodium supplements or very high intake without medical advice.

Fructooligosaccharides commonly cause gas and bloating, especially at higher doses, though doses under 10 grams daily are typically mild. Pectin is well tolerated at food and typical supplement amounts and is likely safe in pregnancy and possibly safe while breastfeeding.

Agar, when taken without plenty of water, can rarely cause blockage (phytobezoars) or bowel obstruction — it's fine as a food but concentrated supplement doses need careful use. We don't have enough safety data on isomaltooligosaccharides in pregnancy or breastfeeding.

Side effects, ingredient by ingredient Sodium Black Psyllium Fructo-oligosaccharides (fos) Agar Pectin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 4 of the 5 matched ingredients can interact with medications — Agar, Black Psyllium, Pectin, Sodium.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: heart-rhythm medications; lithium.
  • For scale: 2,042 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your pharmacist if you take blood pressure medications (antihypertensives), lithium, heart medications like digoxin (Lanoxin) or lovastatin (Mevacor), tetracycline antibiotics, corticosteroids, didanosine (Videx), sodium phosphates, tolvaptan (Samsca), or any other sodium-containing drugs — sodium and pectin can reduce their effectiveness or increase the risk of high blood sodium. The interaction checker on this page can help you verify your exact medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This prebiotic gummy may help support your gut health, especially if you're looking to feed beneficial bacteria. If you take blood pressure medications, lithium, heart medications like digoxin or lovastatin, antibiotics, or any sodium-containing or corticosteroid drugs, check your specific medications with our tool before starting — sodium and pectin can interfere with how several of them work.

Talk with your pharmacist before adding this to your routine if you're on any prescription medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Fiber Sugar-Free Prebiotic Gummies, straight from the product label.

Brand Atlantis Nutrition
Barcode (UPC) X003PUG0TN
Net contents 60 Gummy(ies)
Market status On market
Date entered into DSLD Jul 25, 2024
DSLD ID 316099
Product type Other Combinations
Supplement form Gummy Or Jelly
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Fiber Sugar-Free Prebiotic Gummies by Atlantis Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Gummy(ies)
Maximum serving Sizes:
2 Gummy(ies)
Servings per container
30
UPC/BARCODE
X003PUG0TN
IngredientAmount% DV
Calories20 Calorie(s)--
Total Carbohydrates6 Gram(s)2%
Sodium10 mg2%
Added Sugars0 Gram(s)12%
Total Sugars1 Gram(s)--
Dietary Fiber5 Gram(s)18%
Fructooligosaccharides0 NP--
Agar Agar0 NP--
PreBiotic Digestive Blend5.4 Gram(s)--
Pectin0 NP--
Isomaltooligosaccharides0 NP--

Other ingredients: Water, Citric Acid, Black Carrot Concentrate, Chlorophyll, Trisodium Citrate, Carnauba Wax

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Prebiotic fiber Atlantis Nutritions Fiber Gummies are a delicious & convenient way to support digestive health. These gummies contain a prebiotic digestive blend which works to nourish the good bacteria in your gut & promote a healthy balance. Give your gut the support it needs & enjoy the delicious fruit flavor in every gummy!

Chicory root inulin fiber

Suggested/Recommended/Usage/Directions

Directions: Chew 2 gummies once daily as a dietary supplement or as directed by a qualified health care professional.

Precautions

Warning: Take only as directed. Do not exceed suggested dosage.

Pregnant or nursing mothers, children under 18 or individuals with a known medical condition should consult a physician before using this or any dietary supplement.

This product is manufactured and packed in a facility which may also process milk, soy, wheat, egg, peanuts, tree nuts, fish and crustacean shellfish.

Pregnant or nursing mothers, children under 18 or individuals with a known medical condition should consult a physician before using this or any dietary supplement. Keep out of reach of children.

Do not use if safety seal is damaged or missing.

Storage

This product may settle during shipping.

Store in a cool, dry place.

Formulation

Natural colors will darken over time. This does not alter the potency of the product.

Supports gut health Promotes digestive health

Does not contain soy, wheat, gluten, milk, egg, crustacean shellfish, peanuts.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

Lab tested Made in the USA

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Fiber Sugar-Free Prebiotic Gummies by Atlantis Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Fiber Sugar-Free Prebiotic Gummies label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Fiber Sugar-Free Prebiotic Gummies by Atlantis Nutrition

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Gummy(ies) Dosage formGummy Or Jelly Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Sodium

Interacts with
205 drugs
10 mg per serving

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets g...

Sodium monograph & interactions

Dietary Fiber

Interacts with
2,025 drugs
5 Gram(s) per serving

Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. I...

Dietary Fiber monograph & interactions

PreBiotic Digestive Blend

5.4 Gram(s) per serving

Other (inactive) ingredients: Water, Citric Acid, Black Carrot Concentrate, Chlorophyll, Trisodium Citrate, Carnauba Wax. These complete the product’s ingredient list but are not active constituents.

Interaction report

Fiber Sugar-Free Prebiotic Gummies by Atlantis Nutrition Drug Interactions

Want to check YOUR meds against Fiber Sugar-Free Prebiotic Gummies?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2,041Drugs
250 Moderate 1,791 Minor

Ingredients driving the most interactions

Dietary Fiber 2,025
Agar Agar 2,022
Sodium 205
Pectin 23

Individual Drug Interactions

The ingredients in Fiber Sugar-Free Prebiotic Gummies interact with 2,041 drugs. Click any drug to see the details.

4 of the 6 ingredients in Fiber Sugar-Free Prebiotic Gummies interact with drugs. Each result below shows which ingredient is responsible. Dietary Fiber Agar Agar Sodium Pectin

Each ingredient & the kinds of drugs it affects

For each ingredient in Fiber Sugar-Free Prebiotic Gummies with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Dietary Fiber7 drug types · 2,025 drugs

Carbamazepine (Tegretol)

Theoretically, black psyllium might reduce the effects of carbamazepine and increase the risk for convulsions.
Theoretically, black psyllium might reduce carbamazepine absorption. A preliminary study using blond psyllium reported decreased carbamazepine bioavailability due to binding of the drug to psyllium, as well as reduction of available fluid in the gut for dissolution of the drug. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Lithium

Theoretically, taking black psyllium at the same time as lithium might reduce lithium absorption.
The fiber in black psyllium might reduce lithium absorption and plasma levels. Some case reports describe a reduction in plasma lithium levels with concomitant administration of blond psyllium. This was reversed when psyllium was stopped. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Metformin (Glucophage)

Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Animal research shows that concurrent consumption of blond psyllium with metformin slows and increases the absorption of metformin. This interaction may also occur with black psyllium. To avoid changes in absorption, take psyllium 30-60 minutes after metformin.

Likelihood Possible Evidence D
Olanzapine (Zyprexa)

Theoretically, taking black psyllium at the same time as olanzapine might reduce olanzapine absorption.
The fiber in black psyllium might decrease the absorption of olanzapine. A single case report describes a reduction in the effectiveness of olanzapine when it was concomitantly administered with an unspecified type of psyllium 3 grams orally twice daily. This effect was reversed when psyllium was stopped.

Likelihood Possible Evidence D
Digoxin (Lanoxin)

Theoretically, taking black psyllium at the same time as digoxin might reduce digoxin absorption and decrease digoxin levels.
Psyllium might bind digoxin in the gut. However, some clinical evidence suggests that psyllium does not impact digoxin absorption.

Likelihood Unlikely Evidence B
Ethinyl Estradiol

Theoretically, taking black psyllium at the same time as ethinyl estradiol might alter levels of estradiol.
Concurrent use of blond psyllium with ethinyl estradiol results in a slight increase in the extent of ethinyl estradiol absorption and a slower rate of absorption. This is unlikely to be clinically significant.

Likelihood Unlikely Evidence D
Oral Drugs

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Psyllium seems to have variable effects on drug absorption. To avoid changes in absorption, take psyllium 30-60 minutes after oral medications. Animal research shows that blond psyllium delays and increases the absorption of metformin and ethinyl estradiol. Case reports and animal research suggest that blond psyllium might reduce absorption of lithium, digoxin, olanzapine, and carbamazepine. Finally, some pharmacokinetic studies show that psyllium does not affect the absorption of levothyroxine or warfarin. Although many of these studies evaluated blond psyllium, the fiber content in black psyllium may have similar effects.

Likelihood Possible Evidence B
Dietary Fiber full monograph & interactions

Agar Agar1 drug type · 2,022 drugs

Oral Drugs

Agar forms a thick gel, which may disrupt the absorption of nutrients and medications. Animal research suggests that consuming a diet consisting of 5% to 10% agar alters the absorption of nutrients from the diet. In one study, consuming a diet composed of 10% agar reduced the absorption of all evaluated minerals. Theoretically, agar may also impair the absorption of oral drugs.

Likelihood Possible Evidence D
Agar Agar full monograph & interactions

Sodium7 drug types · 205 drugs

Antihypertensive Drugs

Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
High intake of dietary sodium can increase systolic and diastolic blood pressure. Also, high intake of sodium may necessitate increased use of antihypertensive medications to achieve blood pressure control in some patients, such as those with chronic kidney disease.

Likelihood Probable Evidence A
Corticosteroids

Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Mineralocorticoids and some glucocorticoids (corticosteroids) cause sodium retention. This effect is dose-related and depends on mineralocorticoid potency. It is most common with hydrocortisone, cortisone, and fludrocortisone, followed by prednisone and prednisolone.

Likelihood Possible Evidence D
Didanosine (Videx)

Concomitant use of didanosine with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia.
Didanosine formulations contain a significant amount of sodium.

Likelihood Probable Evidence C
Lithium

Altering dietary intake of sodium might alter the levels and clinical effects of lithium.
High sodium intake can reduce plasma concentrations of lithium by increasing lithium excretion. Reducing sodium intake can significantly increase plasma concentrations of lithium and cause lithium toxicity in patients being treated with lithium carbonate. Stabilizing sodium intake is shown to reduce the percentage of patients with lithium level fluctuations above 0.8 mEq/L. Patients taking lithium should avoid significant alterations in their dietary intake of sodium.

Likelihood Probable Evidence B
Sodium Phosphates

Theoretically, concomitant use of sodium phosphate with sodium supplements might increase the risk of hypernatremia.
Use of high doses (> 45 mL in 24 hours) of sodium phosphate, such as those used for bowel cleansing before surgery, can lead to serious electrolyte disturbances, including hypernatremia. The risk of hypernatremia is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Sodium-Containing Drugs

Concomitant use of sodium-containing drugs with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia and long-term sodium-related complications.
The Chronic Disease Risk Reduction (CDRR) intake level of 2.3 grams of sodium daily indicates the intake at which it is believed that chronic disease risk increases for the apparently healthy population. Some medications contain high quantities of sodium. When used in conjunction with sodium supplements or high-sodium diets, the CDRR may be exceeded. Additionally, concomitant use may increase the risk for hypernatremia; this risk is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Tolvaptan (Samsca)

Theoretically, concomitant use of tolvaptan with sodium might increase the risk of hypernatremia.
Tolvaptan is a vasopressin receptor 2 antagonist that is used to increase sodium levels in patients with hyponatremia. Patients taking tolvaptan should use caution with the use of sodium salts such as sodium chloride.

Likelihood Probable Evidence C
Sodium full monograph & interactions

Pectin3 drug types · 23 drugs

Digoxin (Lanoxin)

Theoretically, pectin might reduce the absorption of digoxin, potentially decreasing its effectiveness.
A small clinical study shows that taking digoxin with a kaolin-pectin suspension reduces the absorption of digoxin by about 62%. It is unclear if these effects are due to pectin, kaolin, or the combination.

Likelihood Possible Evidence B
Lovastatin (Mevacor)

Theoretically, pectin might reduce the absorption of lovastatin, potentially decreasing its effectiveness.
Case reports suggest that concomitant use of pectin and lovastatin might reduce the cholesterol-lowering effect of lovastatin, possibly due to reduced intestinal absorption of lovastatin.

Likelihood Possible Evidence D
Tetracycline Antibiotics

Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.
A small clinical study shows that taking tetracycline with bismuth subsalicylate in a kaolin-pectin suspension reduces the absorption of tetracycline by about 34%. It is unclear if these effects are due to pectin, kaolin, bismuth subsalicylate, or the combination.

Likelihood Possible Evidence B
Pectin full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Fiber Sugar-Free Prebiotic Gummies, from the product label.

Atlantis Nutrition

See all Atlantis Nutrition products
Name
Atlantis Nutrition
Street Address
4470 W Sunset Blvd Suite 107 PMB 94179
City
Los Angeles
State
CA
ZipCode
90027
Web Address
www.atlantisnutrition.com
Pharmacist Counseling Corner

Fiber Sugar-Free Prebiotic Gummies by Atlantis Nutrition: Common Questions

Does Fiber Sugar-Free Prebiotic Gummies by Atlantis Nutrition interact with any medications?
Yes. Based on its ingredients, Fiber Sugar-Free Prebiotic Gummies has a known interaction with 2,041 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Fiber Sugar-Free Prebiotic Gummies contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What does 'prebiotic' mean in this product?
Prebiotic means the gummy contains fiber — specifically fructooligosaccharides and isomaltooligosaccharides — that feeds the good bacteria already living in your gut. It's not a probiotic (which adds bacteria itself); it's food for the bacteria you have.
Will this cause bloating or gas?
Fructooligosaccharides commonly cause bloating, gas, and abdominal pain, especially at higher doses. Studies suggest that doses under 10 grams daily are generally mild, but everyone is different. If you're sensitive to fiber, start slowly and drink plenty of water.
Is this safe to take if I'm pregnant or breastfeeding?
Pectin is likely safe in pregnancy and possibly safe while breastfeeding. We don't have enough data on fructooligosaccharides or isomaltooligosaccharides in pregnancy or breastfeeding — talk with your doctor or pharmacist for personalized advice, especially if you're supplementing beyond normal food amounts.
Can pectin really help lower cholesterol?
Pectin has possibly effective evidence for lowering cholesterol in our data. The other active ingredients — sodium, fructooligosaccharides, agar, and isomaltooligosaccharides — don't have established evidence in our database for lowering cholesterol or the other conditions they might target.
What's the sodium content in these gummies?
The product facts don't specify the amount of sodium per serving, so check the nutrition label on the package. This is important if you're on blood pressure medication, lithium, or other drugs that interact with sodium — your pharmacist can help you figure out whether this fits into your sodium limit.
Should I take this with food or water?
The product facts don't specify timing or fluid requirements. Because agar can cause blockage if taken without enough water, it's wise to take these gummies with a full glass of water — ask your pharmacist if you have questions about how to use them safely.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Fiber Sugar-Free Prebiotic Gummies label
Go deeper

The Full Monographs Behind Fiber Sugar-Free Prebiotic Gummies’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Sodium

Interacts with 205 drugs

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets get more than enough—often too much—from...

Read the full Sodium monograph → Herb & supplement monograph

Black Psyllium

Interacts with 2,025 drugs

Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. It is best known and most studied for rel...

Read the full Black Psyllium monograph → Herb & supplement monograph

Fructo-oligosaccharides (fos)

Fructo-oligosaccharides (FOS) are a type of soluble fiber that acts as a prebiotic, meaning they feed the helpful bacteria in your gut. They are generally considered safe for most people in...

Read the full Fructo-oligosaccharides (fos) monograph → Herb & supplement monograph

Agar

Interacts with 2,022 drugs

Agar is a plant-based gel made from red seaweed that is widely used as a vegetarian alternative to gelatin and as a source of dietary fiber. It is sometimes taken as a bulk-forming laxative...

Read the full Agar monograph → Herb & supplement monograph

Pectin

Interacts with 23 drugs

Pectin is a natural soluble fiber found in fruits like apples and citrus, and it is widely used in foods and as a fiber supplement. It may modestly help with cholesterol, blood sugar, and di...

Read the full Pectin monograph →
Sources

Sources & How We Checked

Fiber Sugar-Free Prebiotic Gummies's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 86 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Sodium 38 references
  1. Garabedian-Ruffalo SM, Ruffalo RL. Drug and nutrient interactions. Am Fam Physician 1986;33:165-74.
  2. Food and Drug Administration Science Background: Safety of Sodium Phosphates Oral Solution. September 17, 2001. Available at: http://www.fda.gov/cder/drug/safety/sodiumphospate.htm
  3. Coton T, Mallaret C, Coilliot C, Carre D, Guisset M. Severe acute ulcerated gastritis induced by salt. Presse Med 2009;38(3):499-500. PubMed
  4. Frings-Meuthen P, Buehlmeier J, Baecker N, et al. High sodium chloride intake exacerbates immobilization-induced bone resorption and protein losses. J Appl Physiol 2011;111(2):537-542. PubMed
  5. Frings-Meuthen P, Baecker N, Heer M. Low-grade metabolic acidosis may be the cause of sodium chloride-induced exaggerated bone resorption. J Bone Miner Res 2008;23(4):517-524. PubMed
  6. Alam S, Johnson AG. A meta-analysis of randomised controlled trials (RCT) among healthy normotensive and essential hypertensive elderly patients to determine the effect of high salt (NaCl) diet of blood pressure. J Hum Hypertens 1999;13(6):367-74.
  7. Boudville N, Ward S, Benaroia M, House AA. Increased sodium intake correlates with greater use of antihypertensive agents by subjects with chronic kidney disease. Am J Hypertens 2005;18(10):1300-5. PubMed
  8. Bennett WM. Drug interactions and consequences of sodium restriction. Am J Clin Nutr 1997;65(2 Suppl):678S-681S. PubMed
  9. Okusa MD, Crystal LJ. Clinical manifestations and management of acute lithium intoxication. Am J Med 1994;97(4):383-9. PubMed
  10. Food and Nutrition Board, Institute of Medicine. Dietary reference intakes for water, potassium, sodium, chloride, and sulfate. Washington, DC: National Academy Press, 2005. Available at: http://www.nap.edu/openbook.php?record_id=10925. DOI
  11. D'Elia L, Rossi G, Ippolito R, Cappuccio FP, Strazzullo P. Habitual salt intake and risk of gastric cancer: a meta-analysis of prospective studies. Clin Nutr 2012;31(4):489-98. PubMed
  12. Goldsmith SR. Hyponatremia in heart failure: time for a trial. J Card Fail 2013;19(6):398-400. PubMed
  13. Willocks L, Brettle R, Keen J, Valentine C, Pinching AJ. Formulations of didanosine (ddI) and salt overload. Lancet 1992;339(8786):190.
  14. Chen L, Zhang Z, Chen W, Whelton PK, Appel LJ. Lower Sodium Intake and Risk of Headaches: Results From the Trial of Nonpharmacologic Interventions in the Elderly. Am J Public Health. 2016;106(7):1270-5. PubMed
  15. Cook NR, Appel LJ, Whelton PK. Lower levels of sodium intake and reduced cardiovascular risk. Circulation. 2014;129(9):981-9. PubMed
  16. Cook NR, Appel LJ, Whelton PK. Sodium Intake and All-Cause Mortality Over 20 Years in the Trials of Hypertension Prevention. J Am Coll Cardiol. 2016;68(15):1609-1617. PubMed
  17. Mente A, O'Donnell M, Rangarajan S, et al. Associations of urinary sodium excretion with cardiovascular events in individuals with and without hypertension: a pooled analysis of data from four studies. Lancet. 2016;388(10043):465-75. PubMed
  18. Moosavian SP, Haghighatdoost F, Surkan PJ, Azadbakht L. Salt and obesity: a systematic review and meta-analysis of observational studies. Int J Food Sci Nutr. 2017;68(3):265-277. PubMed
  19. O'Donnell M, Mente A, Rangarajan S, et al. Urinary sodium and potassium excretion, mortality, and cardiovascular events. N Engl J Med. 2014;371(7):612-23. DOI
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Black Psyllium 18 references
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See these in context on the Black Psyllium monograph →

Fructo-oligosaccharides (fos) 6 references
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  2. Bouhnik Y, Vahedi K, Achour L, et al. Short-chain fructo-oligosaccharide administration dose-dependently increases fecal bifidobacteria in healthy humans. J Nutr 1999;129:113-6. PubMed
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  5. Andermann TM, Fouladi F, Tamburini FB, et al. A Fructo-Oligosaccharide Prebiotic Is Well Tolerated in Adults Undergoing Allogeneic Hematopoietic Stem Cell Transplantation: A Phase I Dose-Escalation Trial. Transplant Cell Ther 2021;27(11):932. PubMed
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See these in context on the Fructo-oligosaccharides (fos) monograph →

Agar 13 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
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  7. Osada, T., Shibuya, T., Kodani, T., Beppu, K., Sakamoto, N., Nagahara, A., Ohkusa, T., Ogihara, T., and Watanabe, S. Obstructing small bowel bezoars due to an agar diet: diagnosis using double balloon enteroscopy. Intern.Med 2008;47(7):617-620. PubMed
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  11. Caglayan, S., Candemir, H., Aksit, S., Kansoy, S., Asik, S., and Yaprak, I. Superiority of oral agar and phototherapy combination in the treatment of neonatal hyperbilirubinemia. Pediatrics 1993;92(1):86-89. DOI
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See these in context on the Agar monograph →

Pectin 11 references
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See these in context on the Pectin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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