Interactions on record — worth a quick check against your medications. Based on 1 of 3 ingredients. Check your meds →
Dietary supplement

Fish Oil Sport Ingredients & Drug Interactions

by GNC Triple Strength

Softgel Capsule Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Fish Oil Sport is a dietary supplement by GNC Triple Strength with 3 active ingredients. Its ingredients are commonly taken for muscle recovery and sports performance, gut health and 'leaky gut', recovery from severe illness or injury.Based on those ingredients, 50 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are L-Glutamine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Fish Oil Sport by GNC Triple Strength

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains 3 active ingredients. L-Glutamine is an amino acid (a building block your body uses for protein and other functions).

Eicosapentaenoic acid and docosahexaenoic acid are omega-3 fatty acids derived from fish — the same healthy fats found in fatty fish like salmon. The softgel capsule also contains inactive ingredients: fish body oil, gelatin, glycerin, an enteric coating (which helps the capsule release lower in your digestive tract), and annatto color.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: cardiovascular, joint health and recovery support.
  • We looked for evidence on: Cardiovascular disease (CVD), Exercise-induced muscle damage, Postoperative recovery, Athletic performance, Anti-inflammatory response, Musculoskeletal recovery — and 2 related terms.
  • The strongest evidence on file: Glutamine is rated "Possibly Effective" for Postoperative recovery (Natural Medicines).
  • Also on file: Glutamine is rated "Possibly Ineffective" for Athletic performance.
  • Also on file: Glutamine is rated "Insufficient Reliable Evidence To Rate" for Cardiovascular disease (CVD), Exercise-induced muscle damage.

L-Glutamine is rated effective for sickle cell disease. It's rated possibly effective for HIV/AIDS-related wasting, postoperative recovery, and critical illness from trauma.

The effectiveness ratings we hold don't cover the omega-3 fatty acids in this product, so we can't tell you what the evidence shows for those components.

The evidence, ingredient by ingredient Glutamine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-Glutamine is generally well tolerated. The most common side effects from oral use are belching, bloating, constipation, diarrhea, flatulence, nausea, vomiting, headache, and gastrointestinal pain — most often seen at higher doses (10 to 30 grams daily).

People with kidney or liver disease should only use it under their doctor's supervision. There isn't enough safety data to recommend it during pregnancy or breastfeeding unless your doctor advises otherwise.

If you have bipolar disorder, discuss this supplement with your doctor first, as rare cases of mania or hypomania have been reported.

Side effects, ingredient by ingredient Glutamine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Glutamine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: seizure medications.
  • For scale: 50 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist if you take anticonvulsant drugs (seizure medications), since L-Glutamine may theoretically work against them. We couldn't check the omega-3 fatty acids in this product for interactions, so confirm your exact medications on this page's interaction tool before you start.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product may help with sickle cell disease and possibly with certain types of wasting or recovery from surgery or critical illness. If you take an anticonvulsant (seizure medication) or any other regular prescription, talk with your own doctor or pharmacist before starting it — especially if you have kidney or liver disease, bipolar disorder, or are pregnant or breastfeeding.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 26, 2011.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Fish Oil Sport, straight from the product label.

Brand GNC Triple Strength
Barcode (UPC) 048107100742
Net contents 120 Softgel(s)
Market status On market
Date entered into DSLD Oct 26, 2011
DSLD ID 1651
Product type Other Combinations
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Fish Oil Sport by GNC Triple Strength, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Softgel(s)
Maximum serving Sizes:
2 Softgel(s)
Servings per container
60
UPC/BARCODE
048107100742
IngredientAmount% DV
Calories15 {Calories}--
L-Glutamine500 mg--
Calories from Fat15 {Calories}--
Total Fat1.5 g2%
Eicosapentaenoic Acid647 mg--
Docosahexaenoic Acid253 mg--

Other ingredients: Fish Body Oil, Gelatin, Glycerin, Enteric Coating, Annatto color

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

DIETARY SUPPLEMENT

Formula

900 mg total omega-3 fatty acids 500 mg glutamine for added recovery support* Supports the cardiovascular system, natural anti-inflammatory repsonse and joint health* Controls fish burps^

Formulation

No Sugar, No Starch, No Artificial Colors, No Artificial Flavors, No Preservatives, No Wheat, No Gluten, No Corn, No Dairy, Yeast Free.

Precautions

CONTAINS: Fish and Soybeans.

KEEP OUT OF REACH OF CHILDREN.

WARNING: Consult your physician prior to using this product if you are pregnant, taking medication, or have a medical condition. Discontinue use two weeks prior to surgery.

Storage

Store in a cool, dry place.

General Statements

^ Enteric Coating controls or reduces the fishy burps.

Conforms to USP <2091> for weight. Potencies verified by GNC procedures #5123 and #5052

Enteric Coated

NEW

General

CODE 886311 LLG

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take two softgel capsules daily.

See for yourself

Fish Oil Sport by GNC Triple Strength label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Fish Oil Sport by GNC Triple Strength

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Softgel(s) Dosage formSoftgel Capsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

L-Glutamine

Interacts with
50 drugs
500 mg per serving

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle c...

L-Glutamine monograph & interactions

Eicosapentaenoic Acid

647 mg per serving

Docosahexaenoic Acid

253 mg per serving

Other (inactive) ingredients: Fish Body Oil, Gelatin, Glycerin, Enteric Coating, Annatto color. These complete the product’s ingredient list but are not active constituents.

Interaction report

Fish Oil Sport by GNC Triple Strength Drug Interactions

Want to check YOUR meds against Fish Oil Sport?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
50Drugs
50 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Fish Oil Sport with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

L-Glutamine1 drug type · 50 drugs

Anticonvulsants

Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Glutamine is metabolized to the excitatory neurotransmitter glutamate. Glutamate might have antagonistic effects with anticonvulsant drugs. However, this interaction has not yet been reported in humans.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Fish Oil Sport, from the product label.

GNC Triple Strength

See all GNC Triple Strength products
Phone Number
1-888-462-2548
Pharmacist Counseling Corner

Fish Oil Sport by GNC Triple Strength: Common Questions

Does Fish Oil Sport by GNC Triple Strength interact with any medications?
Yes. Based on its ingredients, Fish Oil Sport has a known interaction with 50 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Fish Oil Sport contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is L-Glutamine and why is it in a fish oil product?
L-Glutamine is an amino acid your body uses to build and repair tissue, support immune function, and maintain your gut lining. This product combines it with omega-3 fatty acids to support recovery and athletic performance — that's the 'Sport' angle — though the effectiveness data we hold is strongest for sickle cell disease.
What are the most common side effects?
At normal doses, belching, bloating, and mild digestive upset (nausea, constipation, or diarrhea) are the main ones reported. These are more likely at higher doses and usually resolve if you lower your dose or stop.
Is it safe to take while pregnant or breastfeeding?
L-Glutamine is rated likely safe in pregnancy, but during breastfeeding there isn't enough data — talk with your doctor or midwife about whether it's right for you. We don't have pregnancy or breastfeeding data for the omega-3 fatty acids in this product either.
Can I take this if I have kidney or liver disease?
Only under your doctor's supervision. L-Glutamine needs to be processed by your kidneys and liver, so if those organs aren't working normally, you need medical guidance on whether it's safe and what dose is right.
Will this help my athletic performance or recovery?
L-Glutamine is rated possibly effective for postoperative recovery, but we don't have effectiveness data for athletic performance or general 'sports' recovery in our database. Talk with your doctor or a sports nutritionist about whether it fits your specific goals.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Fish Oil Sport is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Fish Oil Sport label
Sources

Sources & How We Checked

Fish Oil Sport's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutamine 11 references
  1. Miller AL. Therapeutic considerations of L-glutamine: a review of the literature. Altern Med Rev 1999;4:239-48..
  2. Bozzetti F, Biganzoli L, Gavazzi C, et al. Glutamine supplementation in cancer patients receiving chemotherapy: a double-blind randomized study. Nutrition 1997;13:748-51.. PubMed
  3. Mebane AH. L-Glutamine and mania. Am J Psychiatry 984;141:1302-3.
  4. Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000;130:1007S-15S.. PubMed
  5. Garlick PJ. Assessment of the safety of glutamine and other amino acids. J Nutr 2001;131:2556S-61S.. PubMed
  6. Chapman AG. Glutamate and epilepsy. J Nutr 2000;130:1043S-5S.. PubMed
  7. Ziegler TR. Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy. J Nutr 2001;131:2578S-84S.. PubMed
  8. Laviano A, Molfino A, Lacaria MT, Canelli A, De Leo S, Preziosa I, Rossi Fanelli F. Glutamine supplementation favors weight loss in nondieting obese female patients. A pilot study. Eur J Clin Nutr. 2014 Nov;68(11):1264-6. PubMed
  9. Endari (l-glutamine) [package insert]. Torrance, CA: Emmaus Medical,Inc; 2017.
  10. Niihara Y, Miller ST, Kanter J, et al. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. N Engl J Med 2018;379(3):226-35. doi: 10.1056/NEJMoa1715971.
  11. Ogden HB, Child RB, Fallowfield JL, et al. Gastrointestinal Tolerance of Low, Medium and High Dose Acute Oral l-Glutamine Supplementation in Healthy Adults: A Pilot Study. Nutrients. 2020;12(10):2953. PubMed

See these in context on the Glutamine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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