For Men Only Ingredients & Drug Interactions
by Herb Stop
What is this page for?
First and foremost: checking For Men Only against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
For Men Only is a dietary supplement by Herb Stop with 6 active ingredients. Its ingredients are commonly taken for benign prostatic hyperplasia (bph) symptoms, urinary problems, hair loss.Based on those ingredients, 1,385 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Barberry extract, Buchu extract, Cayenne extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against For Men Only by Herb Stop
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HelloPharmacist Scorecard of For Men Only by Herb Stop
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
For Men Only contains 6 active ingredients: saw palmetto extract, pygeum extract, barberry extract, cayenne extract, cornsilk extract, and buchu extract. The product also includes grape alcohol and water as inactive ingredients.
Saw palmetto and pygeum are traditionally used for prostate health, while the other botanicals provide supporting compounds.
Does it work?
Strong evidence
Pygeum is likely effective for benign prostatic hyperplasia (BPH), a common condition in older men. Cayenne extract is likely effective for nerve pain after shingles (postherpetic neuralgia) and diabetic nerve pain, and possibly effective for cluster headaches and back pain.
Saw palmetto is rated possibly ineffective for BPH despite being a common choice for it. The evidence for the other uses — saw palmetto for urinary symptoms, barberry for various conditions, and buchu — is either insufficient or not established in the data we hold.
How safe is it?
Well-documented data
Saw palmetto is generally well tolerated, though mild side effects like abdominal pain, constipation, diarrhea, dizziness, and headache are reported. Rare cases of heart problems (including heart attacks and arrhythmias) and a single report of severe heart rhythm abnormality have been documented.
Pygeum and cayenne are also generally well tolerated; cayenne commonly causes burning and irritation. Barberry safety data are limited, and a serious case of liver injury and blood cell failure was reported with long-term use.
Buchu lacks robust safety data for medicinal doses. Pregnancy and breastfeeding: saw palmetto and barberry are likely unsafe during pregnancy and should be avoided.
Buchu is likely unsafe in pregnancy and possibly safe while breastfeeding. Cayenne at food amounts is likely safe in pregnancy and breastfeeding, but medicinal doses are not well studied.
Pygeum and cornsilk safety data during pregnancy and lactation are not on file — talk with your doctor or pharmacist before using if you're pregnant or nursing.
Meds to double-check
Moderate interaction found
Before taking this product, check with your doctor or pharmacist if you use blood thinners or antiplatelet drugs (including aspirin and warfarin), diabetes medications, birth control, blood pressure drugs, sedatives, heart rhythm or anticholinergic drugs, theophylline, ciprofloxacin, cyclosporine, lithium, or medications that stress the liver. These are the medication types with documented interactions across the product's ingredients.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product combines several plant extracts traditionally used for men's urinary and prostate health, though the evidence supporting them is mixed. If you take any medications — especially blood thinners, diabetes drugs, contraceptives, blood pressure medicines, or lithium — check each of your prescriptions with the tool on this page before starting.
Avoid this product if you're pregnant or breastfeeding unless your doctor or pharmacist has reviewed it for you personally.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 5 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about For Men Only, straight from the product label.
| Brand | Herb Stop |
|---|---|
| Net contents | 1 Ounce(s); 30 Milliliter(s) |
| Market status | On market |
| Date entered into DSLD | Sep 25, 2023 |
| DSLD ID | 297304 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Women (not pregnant or lactating), Adult Male (18-50 Years), Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for For Men Only by Herb Stop, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Extract Blend | 0 NP | -- |
| Saw Palmetto extract | 0 NP | -- |
| Pygeum extract | 0 NP | -- |
| Barberry extract | 0 NP | -- |
| Cayenne extract | 0 NP | -- |
| Cornsilk Extract | 0 NP | -- |
| Buchu extract | 0 NP | -- |
Other ingredients: Grape Alcohol, Water
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested Use: Take 30 drops in a small amount of water, 3-4 times daily or as directed.
Precautions
Safety Guideline: Not to be used during pregnancy or lactation. If you have a medical condition or take pharmaceuticals drugs, please consult with your doctor before use.
Keep away from children.
Use only as directed on label.
Brand IP Statement(s)
Herb Stop Healthy In Your Own Hands
Formula
Liquid Herbal Extract
Formulation
Supports healthy prostate function
77% Organic Content
Vegan & Cruelty-Free
Vegan & Cruelty-Free
Made in the USA.
FDA Statement of Identity
Dietary Supplement
FDA Disclaimer Statement
These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
For Men Only by Herb Stop label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in For Men Only by Herb Stop
These are the 6 active ingredients this product is made of. Select any to open its full monograph.
Serving size30 Drop(s) Dosage formLiquid Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Extract Blend
- › Saw Palmetto extract
- › Pygeum extract
- › Barberry extract
- › Cayenne extract
- › Cornsilk Extract
- › Buchu extract
Other (inactive) ingredients: Grape Alcohol, Water. These complete the product’s ingredient list but are not active constituents.
For Men Only by Herb Stop Drug Interactions
HelloPharmacist Interaction Report
Herb Stop For Men Only interacts with medications through its saw palmetto, barberry, cayenne, and buchu extracts.
The most serious documented interaction is a Moderate risk of reduced contraceptive effectiveness with saw palmetto, which may interfere with how birth control drugs work.
Read the full breakdown — every affected drug type, severity by severity
Saw palmetto also raises Moderate concerns with blood thinners (anticoagulants) and drugs that prevent clots (antiplatelet drugs) — it may prolong bleeding time and increase bleeding risk. Separately, it can reduce the effectiveness of estrogen-based medications.
Barberry extract carries Moderate interactions with sedatives and sleep aids, blood pressure drugs, diabetes medications, blood thinners, heart rhythm drugs (anticholinergic and cholinergic drugs), and drugs metabolized through the CYP3A4 enzyme pathway — including cyclosporine. Cayenne extract poses Moderate risks with blood thinners, diabetes drugs, and theophylline (an asthma/breathing medication), plus Minor concerns with certain blood pressure drugs and the antibiotic ciprofloxacin.
Buchu extract may interact with blood thinners, drugs that stress the liver, and lithium.
Pygeum and cornsilk extract have no known interactions documented in our data — though we hold no data at all for cornsilk. Altogether, these interactions span 1,386 individual medications.
Use the interaction checker on this page to search your exact prescriptions before starting.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against For Men Only?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in For Men Only interact with 1,385 drugs. Click any drug to see the details.
4 of the 6 ingredients in For Men Only interact with drugs. Each result below shows which ingredient is responsible. Barberry extract Buchu extract Cayenne extract Saw Palmetto extract
AliskirenTekturna
How Aliskiren interacts with For Men Only — through 1 ingredient. Tap an ingredient for the detail:
Barberry ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Barberry Extract + Aliskiren interactionAllopurinolCaplenal, Cosuric, Rimapurinol, Zyloprim, Zyloric
How Allopurinol interacts with For Men Only — through 1 ingredient. Tap an ingredient for the detail:
Buchu ExtractHepatotoxic Drugs Moderate
Interaction Summary
Buchu contains pulegone, a known hepatotoxin.
Read the full Buchu Extract + Allopurinol interactionAlmotriptanAlmogran, Axert
How Almotriptan interacts with For Men Only — through 1 ingredient. Tap an ingredient for the detail:
Barberry ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Barberry Extract + Almotriptan interactionAlogliptinNesina
How Alogliptin interacts with For Men Only — through 3 ingredients. Tap an ingredient for the detail:
Barberry ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Antidiabetes Drugs Moderate
Interaction Summary
Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Barberry Extract + Alogliptin interactionBuchu ExtractHepatotoxic Drugs Moderate
Interaction Summary
Buchu contains pulegone, a known hepatotoxin.
Read the full Buchu Extract + Alogliptin interactionCayenne ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking capsicum with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Cayenne Extract + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with For Men Only — through 2 ingredients. Tap an ingredient for the detail:
Cayenne ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking capsicum with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Cayenne Extract + Alogliptin, Metformin interactionBarberry ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking European barberry with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Barberry Extract + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with For Men Only — through 3 ingredients. Tap an ingredient for the detail:
Barberry ExtractAntidiabetes Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking European barberry with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Barberry Extract + Alogliptin, Pioglitazone interactionCayenne ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking capsicum with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Cayenne Extract + Alogliptin, Pioglitazone interactionBuchu ExtractHepatotoxic Drugs Moderate
Interaction Summary
Buchu contains pulegone, a known hepatotoxin.
Read the full Buchu Extract + Alogliptin, Pioglitazone interactionAlpelisibPiqray
How Alpelisib interacts with For Men Only — through 1 ingredient. Tap an ingredient for the detail:
Barberry ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Barberry Extract + Alpelisib interactionAlprazolamNiravam, Xanax
How Alprazolam interacts with For Men Only — through 1 ingredient. Tap an ingredient for the detail:
Barberry ExtractCns Depressants, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use with drugs that have sedative properties may cause additive effects.
Read the full Barberry Extract + Alprazolam interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with For Men Only — through 4 ingredients. Tap an ingredient for the detail:
Buchu ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Buchu may have antiplatelet effects.
Read the full Buchu Extract + Alteplase, Tpa interactionBarberry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, European barberry may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Barberry Extract + Alteplase, Tpa interactionCayenne ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, capsicum may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Cayenne Extract + Alteplase, Tpa interactionSaw Palmetto ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto Extract + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with For Men Only — through 4 ingredients. Tap an ingredient for the detail:
Saw Palmetto ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto Extract + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionBuchu ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Buchu may have antiplatelet effects.
Read the full Buchu Extract + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionBarberry ExtractCns Depressants, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use with drugs that have sedative properties may cause additive effects.
Read the full Barberry Extract + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionCayenne ExtractAnticoagulant/antiplatelet Drugs, Aspirin Moderate
Interaction Summary
Theoretically, capsicum may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Cayenne Extract + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with For Men Only — through 4 ingredients. Tap an ingredient for the detail:
Barberry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, European barberry may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Barberry Extract + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionBuchu ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Buchu may have antiplatelet effects.
Read the full Buchu Extract + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionCayenne ExtractAspirin, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking capsicum with aspirin might reduce the bioavailability of aspirin.
Read the full Cayenne Extract + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionSaw Palmetto ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto Extract + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAmantadineGocovri, Osmolex ER, Symmetrel
How Amantadine interacts with For Men Only — through 1 ingredient. Tap an ingredient for the detail:
Barberry ExtractAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, taking European barberry with anticholinergic drugs might cause additive effects.
Read the full Barberry Extract + Amantadine interactionAmbenonium ChlorideMytelase
How Ambenonium Chloride interacts with For Men Only — through 1 ingredient. Tap an ingredient for the detail:
Barberry ExtractCholinergic Drugs Moderate
Interaction Summary
Theoretically, taking European barberry with cholinergic drugs might decrease the effects of cholinergic drugs.
Read the full Barberry Extract + Ambenonium Chloride interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with For Men Only — through 2 ingredients. Tap an ingredient for the detail:
Buchu ExtractHepatotoxic Drugs Moderate
Interaction Summary
Buchu contains pulegone, a known hepatotoxin.
Read the full Buchu Extract + Ambrisentan interactionBarberry ExtractAntihypertensive Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking European barberry with antihypertensive drugs might increase the risk of hypotension.
Read the full Barberry Extract + Ambrisentan interactionAmifampridineRuzurgi
How Amifampridine interacts with For Men Only — through 1 ingredient. Tap an ingredient for the detail:
Barberry ExtractCholinergic Drugs Moderate
Interaction Summary
Theoretically, taking European barberry with cholinergic drugs might decrease the effects of cholinergic drugs.
Read the full Barberry Extract + Amifampridine interactionAmifampridine PhosphateFirdapse
How Amifampridine Phosphate interacts with For Men Only — through 1 ingredient. Tap an ingredient for the detail:
Barberry ExtractCholinergic Drugs Moderate
Interaction Summary
Theoretically, taking European barberry with cholinergic drugs might decrease the effects of cholinergic drugs.
Read the full Barberry Extract + Amifampridine Phosphate interactionAmilorideAmilamont, Midamor
How Amiloride interacts with For Men Only — through 1 ingredient. Tap an ingredient for the detail:
Barberry ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking European barberry with antihypertensive drugs might increase the risk of hypotension.
Read the full Barberry Extract + Amiloride interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with For Men Only — through 1 ingredient. Tap an ingredient for the detail:
Barberry ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking European barberry with antihypertensive drugs might increase the risk of hypotension.
Read the full Barberry Extract + Amiloride, Hydrochlorothiazide interactionAminoglutethimideCytadren
How Aminoglutethimide interacts with For Men Only — through 1 ingredient. Tap an ingredient for the detail:
Barberry ExtractCns Depressants, Anticholinergic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with drugs that have sedative properties may cause additive effects.
Read the full Barberry Extract + Aminoglutethimide interactionAminophylline, Amobarbital, EphedrineAmesec
How Aminophylline, Amobarbital, Ephedrine interacts with For Men Only — through 1 ingredient. Tap an ingredient for the detail:
Barberry ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs that have sedative properties may cause additive effects.
Read the full Barberry Extract + Aminophylline, Amobarbital, Ephedrine interactionAminosalicylic AcidPaser
How Aminosalicylic Acid interacts with For Men Only — through 1 ingredient. Tap an ingredient for the detail:
Buchu ExtractHepatotoxic Drugs Moderate
Interaction Summary
Buchu contains pulegone, a known hepatotoxin.
Read the full Buchu Extract + Aminosalicylic Acid interactionAmiodaroneCordarone, Pacerone
How Amiodarone interacts with For Men Only — through 2 ingredients. Tap an ingredient for the detail:
Buchu ExtractHepatotoxic Drugs Moderate
Interaction Summary
Buchu contains pulegone, a known hepatotoxin.
Read the full Buchu Extract + Amiodarone interactionBarberry ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Barberry Extract + Amiodarone interactionAmitriptylineElavil
How Amitriptyline interacts with For Men Only — through 1 ingredient. Tap an ingredient for the detail:
Barberry ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cns Depressants +1 Moderate
Interaction Summary
Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Barberry Extract + Amitriptyline interactionAmitriptyline, ChlordiazepoxideLimbitrol DS
How Amitriptyline, Chlordiazepoxide interacts with For Men Only — through 1 ingredient. Tap an ingredient for the detail:
Barberry ExtractAnticholinergic Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, taking European barberry with anticholinergic drugs might cause additive effects.
Read the full Barberry Extract + Amitriptyline, Chlordiazepoxide interactionAmitriptyline, PerphenazineEtrafon, Etrafon-A, Etrafon-Forte, Triavil
How Amitriptyline, Perphenazine interacts with For Men Only — through 1 ingredient. Tap an ingredient for the detail:
Barberry ExtractCns Depressants, Anticholinergic Drugs +1 Moderate
Interaction Summary
Theoretically, concomitant use with drugs that have sedative properties may cause additive effects.
Read the full Barberry Extract + Amitriptyline, Perphenazine interactionAmlodipineNorliqva
How Amlodipine interacts with For Men Only — through 1 ingredient. Tap an ingredient for the detail:
Barberry ExtractAntihypertensive Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking European barberry with antihypertensive drugs might increase the risk of hypotension.
Read the full Barberry Extract + Amlodipine interactionAmlodipine BenzoateKaterzia
How Amlodipine Benzoate interacts with For Men Only — through 1 ingredient. Tap an ingredient for the detail:
Barberry ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Barberry Extract + Amlodipine Benzoate interactionAmlodipine BesilateIstin
How Amlodipine Besilate interacts with For Men Only — through 1 ingredient. Tap an ingredient for the detail:
Barberry ExtractAntihypertensive Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking European barberry with antihypertensive drugs might increase the risk of hypotension.
Read the full Barberry Extract + Amlodipine Besilate interactionAmlodipine BesylateNorvasc
How Amlodipine Besylate interacts with For Men Only — through 1 ingredient. Tap an ingredient for the detail:
Barberry ExtractAntihypertensive Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking European barberry with antihypertensive drugs might increase the risk of hypotension.
Read the full Barberry Extract + Amlodipine Besylate interactionAmlodipine Besylate, BenazeprilLotrel
How Amlodipine Besylate, Benazepril interacts with For Men Only — through 2 ingredients. Tap an ingredient for the detail:
Barberry ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Barberry Extract + Amlodipine Besylate, Benazepril interactionCayenne ExtractAce Inhibitors (aceis) Minor
Interaction Summary
Theoretically, using topical capsaicin may increase the risk of ACE inhibitor-induced cough.
Read the full Cayenne Extract + Amlodipine Besylate, Benazepril interactionEach ingredient & the kinds of drugs it affects
For each ingredient in For Men Only with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Barberry extract
Anticholinergic Drugs
Theoretically, taking European barberry with anticholinergic drugs might cause additive effects.
In vitro evidence suggests that European barberry might have anticholinergic properties.
Anticoagulant/Antiplatelet Drugs
Theoretically, European barberry may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro and animal evidence suggest that berberine, a constituent of European barberry, might inhibit platelet aggregation. Theoretically, European barberry might have a similar effect.
Antidiabetes Drugs
Theoretically, taking European barberry with antidiabetes drugs might increase the risk of hypoglycemia.
Preliminary clinical evidence suggests that European barberry juice reduces fasting glucose levels in patients with type 2 diabetes who are also taking antidiabetes drugs. Additionally, some animal studies show that berberine, a constituent of European barberry, has antiglycemic potential. Monitor blood glucose levels closely.
Antihypertensive Drugs
Theoretically, taking European barberry with antihypertensive drugs might increase the risk of hypotension.
Animal and human research suggests that European barberry extracts can have hypotensive effects.
Cholinergic Drugs
Theoretically, taking European barberry with cholinergic drugs might decrease the effects of cholinergic drugs.
In vitro evidence suggests that European barberry might have anticholinergic properties.
Cns Depressants
Theoretically, concomitant use with drugs that have sedative properties may cause additive effects.
Animal research suggests that berberine, a constituent of European barberry, might have sedative effects. Theoretically, European barberry might have a similar effect.
Cyclosporine (Neoral, Sandimmune)
Theoretically, concomitant use with cyclosporine may cause additive effects.
Berberine, a constituent of European barberry, can reduce the metabolism and increase serum levels of cyclosporine. This effect is attributed to the ability of berberine to inhibit cytochrome P450 3A4 (CYP3A4), which metabolizes cyclosporine. Theoretically, European barberry might have a similar effect.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.
There is very preliminary evidence suggesting that berberine, a constituent of European barberry, might inhibit the CYP3A4 enzyme. Theoretically, European barberry might have a similar effect.
Buchu extract
Anticoagulant/Antiplatelet Drugs
Buchu may have antiplatelet effects. Theoretically, buchu may enhance the effects of anticoagulant or antiplatelet drugs and increase the risk of bleeding in some patients. Some anticoagulant or antiplatelet drugs include aspirin, clopidogrel (Plavix), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, ticlopidine (Ticlid), warfarin (Coumadin), and others.
Hepatotoxic Drugs
Buchu contains pulegone, a known hepatotoxin. There is some concern that buchu may adversely affect the liver, especially when the leaf is used in large doses or the oil is ingested. Theoretically, concomitant use with hepatotoxic drugs might increase the risk of liver damage. Some of these drugs include acarbose (Precose, Prandase), amiodarone (Cordarone), atorvastatin (Lipitor), azathioprine (Imuran), carbamazepine (Tegretol), cerivastatin (Baycol), diclofenac (Voltaren), felbamate (Felbatol), fenofibrate (Tricor), fluvastatin (Lescol), gemfibrozil (Lopid), isoniazid, itraconazole, (Sporanox), ketoconazole (Nizoral), leflunomide (Arava), lovastatin (Mevacor), methotrexate (Rheumatrex), nevirapine (Viramune), niacin, nitrofurantoin (Macrodantin), pioglitazone (Actos), pravastatin (Pravachol), pyrazinamide, rifampin (Rifadin), ritonavir (Norvir), rosiglitazone (Avandia), simvastatin (Zocor), tacrine (Cognex), tamoxifen, terbinafine (Lamisil), valproic acid, and zileuton (Zyflo)
Lithium
Buchu is thought to have diuretic properties. Theoretically, buchu might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.
Cayenne extract
Anticoagulant/Antiplatelet Drugs
Theoretically, capsicum may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro research shows that capsicum might increase the effects of antiplatelet drugs. Also, population research shows that capsicum is associated with an increased risk of self-reported bleeding in patients taking warfarin. However, clinical research shows that taking a single dose of capsaicin (Asian Herbex Ltd.), the active ingredient in capsicum, 400-800 mcg orally in combination with aspirin 500 mg does not decrease platelet aggregation when compared with taking aspirin 500 mg alone. Also, there was no notable effect on measures of platelet aggregation with capsaicin. It is unclear whether capsaicin must be used in more than a single dose to affect platelet aggregation.
Antidiabetes Drugs
Theoretically, taking capsicum with antidiabetes drugs might increase the risk of hypoglycemia.
Preliminary clinical research shows that consuming capsicum 5 grams along with a glucose drink attenuates the rise in plasma glucose after 30 minutes by 21%, decreases the 2-hour postprandial area under the curve of plasma glucose by 11%, and increases the 2-hour postprandial area under the curve of plasma insulin by 58% in healthy individuals when compared with placebo. Other clinical research shows that taking capsicum 5 mg daily for 28 days significantly reduces postprandial blood glucose and insulin levels, but not fasting blood glucose and insulin levels, in patients with gestational diabetes.
Aspirin
Theoretically, taking capsicum with aspirin might reduce the bioavailability of aspirin.
Animal research shows that acute or chronic intake of capsicum pepper reduces oral aspirin bioavailability. This has not been shown in humans.
Theophylline
Theoretically, taking capsicum with theophylline might increase the levels and adverse effects of theophylline.
In animal research, oral administration of capsicum reduced excretion of theophylline. However, capsicum does not seem to affect the pharmacokinetics of theophylline when administered intravenously.
Ace Inhibitors (Aceis)
Theoretically, using topical capsaicin may increase the risk of ACE inhibitor-induced cough.
There is one case report of a topically applied capsaicin cream contributing to the cough reflex in a patient using an ACEI. However, it is unclear if this interaction is clinically significant.
Ciprofloxacin (Cipro)
Theoretically, taking capsicum with ciprofloxacin might increase levels and adverse effects of ciprofloxacin.
Animal research shows that concomitant use of capsaicin, the active constituent of capsicum, and ciprofloxacin increases the bioavailability of ciprofloxacin by up to 70%.
Saw Palmetto extract
Anticoagulant/Antiplatelet Drugs
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Saw palmetto is reported to prolong bleeding time. Theoretically, it might increase the risk of bleeding when used concomitantly with anticoagulant or antiplatelet drugs.
Contraceptive Drugs
Saw palmetto might reduce the effectiveness of contraceptive drugs.
Saw palmetto might have antiestrogenic effects. Theoretically, it might interfere with contraceptive drugs taken concomitantly.
Estrogens
Saw palmetto might reduce the effectiveness of estrogens.
Saw palmetto might have antiestrogenic effects. Theoretically, it might interfere with estrogens taken concomitantly.
Brand information
Manufacturer and brand details for For Men Only, from the product label.
Herb Stop
See all Herb Stop products- Name
- The Herb Stop
- Street Address
- PO Box 673
- City
- Pine
- State
- AZ
- ZipCode
- 85544
- Phone Number
- 877.345.4372
- Web Address
- www.herbstop.com
For Men Only by Herb Stop: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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The Full Monographs Behind For Men Only’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Saw Palmetto
Interacts with 174 drugsSaw palmetto is a plant extract most often used for urinary symptoms linked to an enlarged prostate (BPH). The best research suggests it works no better than a placebo for most men, though i...
Read the full Saw Palmetto monograph → Herb & supplement monographPygeum
Pygeum is an extract from the bark of the African cherry tree that is most often used to ease urinary symptoms linked to an enlarged prostate. Some studies suggest modest benefit for these s...
Read the full Pygeum monograph → Herb & supplement monographEuropean Barberry
Interacts with 1,210 drugsEuropean barberry is a shrub whose root, bark, and berries contain berberine, a bitter plant alkaloid that has been studied mostly in isolated form. Some early research on berberine is promi...
Read the full European Barberry monograph → Herb & supplement monographCapsicum
Interacts with 239 drugsCapsicum (chili pepper) contains capsaicin, which is best known and best studied as a topical treatment for certain types of pain. Topical capsaicin products are supported by reasonable evid...
Read the full Capsicum monograph → Herb & supplement monographBuchu
Interacts with 481 drugsBuchu is a fragrant South African shrub whose leaves are traditionally used for urinary and bladder complaints and as a diuretic. Solid human studies are lacking, so its benefits are largely...
Read the full Buchu monograph →Sources & How We Checked
For Men Only's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 132 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Saw Palmetto 22 references
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- Carraro JC, Raynaud JP, Koch G, et al. Comparison of phytotherapy (Permixon) with finasteride in the treatment of benign prostate hyperplasia: a randomized international study of 1,098 patients. Prostate 1996;29:231-40. DOI
- Di Silverio F, D'Eramo G, Lubrano C, et al. Evidence that Serenoa repens extract displays an antiestrogenic activity in prostatic tissue of benign prostatic hypertrophy patients. Eur Urol 1992;21:309-14. PubMed
- Stepanov VN, Siniakova LA, Sarrazin B, Raynaud JP. Efficacy and tolerability of the lipidosterolic extract of Serenoa repens (Permixon) in benign prostatic hyperplasia: a double-blind comparison of two dosage regimens. Adv Ther 1999;16:231-41.
- Cheema P, El-Mefty O, Jazieh AR. Intraoperative haemorrhage associated with the use of extract of Saw Palmetto herb: a case report and review of literature. J Intern Med 2001;250:167-9. PubMed
- Jibrin I, Erinle A, Saidi A, Aliyu ZY. Saw palmetto-induced pancreatitis. South Med J 2006;99:611-2. PubMed
- Prager N, Bickett K, French N, Marcovici G. A randomized, double-blind, placebo-controlled trial to determine the effectiveness of botanically derived inhibitors of 5-alpha-reductase in the treatment of androgenetic alopecia. J Altern Complement Med 2002
- Avins AL, Bent S, Staccone S, et al. A detailed safety assessment of a saw palmetto extract. Complement Ther Med 2008;16:147-54. PubMed
- Morgia, G., Mucciardi, G., Gali, A., Madonia, M., Marchese, F., Di, Benedetto A., Romano, G., Bonvissuto, G., Castelli, T., Macchione, L., and Magno, C. Treatment of chronic prostatitis/chronic pelvic pain syndrome category IIIA with Serenoa repens plus
- Aliaev, IuG, Vinarov, A. Z., Lokshin, K. L., and Spivak, L. G. [Efficiency and safety of prostamol-Uno in patients with chronic abacterial prostatitis]. Urologiia. 2006;(1):47-50.
- Agbabiaka, T. B., Pittler, M. H., Wider, B., and Ernst, E. Serenoa repens (saw palmetto): a systematic review of adverse events. Drug Saf 2009;32(8):637-647. PubMed
- Wargo, K. A., Allman, E., and Ibrahim, F. A possible case of saw palmetto-induced pancreatitis. South.Med.J. 2010;103(7):683-685. PubMed
- Lapi, F., Gallo, E., Giocaliere, E., Vietri, M., Baronti, R., Pieraccini, G., Tafi, A., Menniti-Ippolito, F., Mugelli, A., Firenzuoli, F., and Vannacci, A. Acute liver damage due to Serenoa repens: a case report. Br.J.Clin.Pharmacol. 2010;69(5):558-560.
- Mantovani, F. Serenoa repens in benign prostatic hypertrophy: analysis of 2 Italian studies. Minerva Urol.Nefrol. 2010;62(4):335-340.
- Hanaka, M., Yoshii, C., Yatera, K., Ito, C., Chojin, Y., Nagata, S., Yamasaki, K., Nishida, C., Kawanami, T., Kawanami, Y., Ishimoto, H., and Mukae, H. [A case of rhabdomyolysis caused by saw palmetto of healthy foods]. J.UOEH. 6-1-2012;34(2):193-199. PubMed
- Miroddi, M., Carni, A., Mannucci, C., Moleti, M., Navarra, M., and Calapai, G. Hot flashes in a young girl: a wake-up call concerning Serenoa repens use in children. Pediatrics 2012;130(5):e1374-e1376.
- Braeckman J. The extract of Serenoa repens in the treatment of benign prostatic hyperplasia: a multicenter open study. Current Therapeutic Research 1994;55(7):776-785. DOI
- Jipescu D, Patel A, Bohra H, Pientka A. Rare case of saw palmetto induced heart block. JACC 2017;69(11) supplement:2310.
- Morabito P, Miroddi M, Giovinazzo S, Spina E, Calapai G. Serenoa repens as an endocrine disruptor in a 10-year-Old young girl: a new case report. Pharmacology. 2015;96(1-2):41-3. doi: 10.1159/000431327.
- Gammoudi R, Ameur K, Ouni B, et al. Fixed drug eruption to Serenoa repens: first case report and consideration of the use of herbal medicine. Dermatol Ther 2020 Aug 29:e14247.
- Paulis G, Paulis A, Perletti G. Serenoa repens and its effects on male sexual function. A systematic review and meta-analysis of clinical trials. Arch Ital Urol Androl 2021;93(4):475-480. PubMed
- Venkateswaran S, Declet-Bauzo R, Shodeinde M, Gilford P. Postoperative Retroperitoneal Hematoma: A Case of Saw Palmetto and the Importance of Primary Care Intervention. HCA Healthc J Med 2020;1(5):279-282. PubMed
Pygeum 3 references
- Ishani A, MacDonald R, Nelson D, et al. Pygeum africanum for the treatment of patients with benign prostatic hyperplasia: a systematic review and quantitative meta-analysis. Am J Med 2000;109:654-64.. PubMed
- Wilt T, Ishani A, Mac Donald R, et al. Pygeum africanum for benign prostatic hyperplasia. Cochrane Database Syst Rev 2002;CD001044.. PubMed
- Andro M and Riffaud J. Pygeum africanum extract for the treatment of patients with benign prostatic hyperplasia: a review of 25 years of published experience. Curr Ther Res 1995;56(8):796-817. DOI
European Barberry 15 references
- Chan E. Displacement of bilirubin from albumin by berberine. Biol Neonate 1993;63:201-8. PubMed
- Wu X, Li Q, Xin H, Yu A, Zhong M. Effects of berberine on the blood concentration of cyclosporin A in renal transplanted recipients: clinical and pharmacokinetic study. Eur J Clin Pharmacol 2005;61:567-72. PubMed
- Shamsa F, Ahmadiani A, Khosrokhavar R. Antihistaminic and anticholinergic activity of barberry fruit (Berberis vulgaris) in the guinea-pig ileum. J Ethnopharmacol 1999;64:161-6. PubMed
- Fatehi M, Saleh TM, Fatehi-Hassanabad Z, et al. A pharmacological study on Berberis vulgaris fruit extract. J Ethnopharmacol 2005;102:46-52. PubMed
- Kostalova, D., Bukovsky, M., Koscova, H., and Kardosova, A. [Anticomplement activity of Mahonia aquifolium bisbenzylisoquinoline alkaloids and berberine extract]. Ceska.Slov.Farm 2001;50(6):286-289.
- Fatehi-Hassanabad, Z., Jafarzadeh, M., Tarhini, A., and Fatehi, M. The antihypertensive and vasodilator effects of aqueous extract from Berberis vulgaris fruit on hypertensive rats. Phytother Res 2005;19(3):222-225.
- Singh, J. and Kakkar, P. Antihyperglycemic and antioxidant effect of Berberis aristata root extract and its role in regulating carbohydrate metabolism in diabetic rats. J Ethnopharmacol. 5-4-2009;123(1):22-26. PubMed
- Shanbhag, S. M., Kulkarni, H. J., and Gaitonde, B. B. Pharmacological actions of berberine on the central nervous system. Jpn.J Pharmacol 1970;20(4):482-487. PubMed
- Wu, J. F. and Liu, T. P. [Effects of berberine on platelet aggregation and plasma levels of TXB2 and 6-keto-PGF1 alpha in rats with reversible middle cerebral artery occlusion]. Yao Xue.Xue.Bao. 1995;30(2):98-102.
- Xuan, B., Wang, W., and Li, D. X. Inhibitory effect of tetrahydroberberine on platelet aggregation and thrombosis. Zhongguo Yao Li Xue.Bao. 1994;15(2):133-135.
- Gao, C. R., Zhang, J. Q., and Huang, Q. L. [Experimental study on berberin raised insulin sensitivity in insulin resistance rat models]. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. 1997;17(3):162-164. DOI
- Sabir M and Bhide NK. Study of some pharmacological actions of berberine. Ind J Physiol & Pharmac 1971;15(3):111-132.
- Tripathi YB and Shukla SD. Berberis artistata inhibits PAF induced aggregation of rabbit platelets. Phytotherapy Research 1996;10:628-630.
- Lazavi F, Mirmiran P, Sohrab G, Nikpayam O, Angoorani P, Hedayati M. The barberry juice effects on metabolic factors and oxidative stress in patients with type 2 diabetes: A randomized clinical trial. Complement Ther Clin Pract. 2018;31:170-174. PubMed
- Philips CA, Theruvath AH, Ravindran R. Toxic hepatitis-associated aplastic anaemia after dual homeopathic remedies and Gymnema sylvestre use. BMJ Case Rep 2022;15(3):e247867. PubMed
Capsicum 89 references
- Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
- Cooper RL, Cooper MM. Red pepper-induced dermatitis in breast-fed infants. Dermatol 1996;93:61-2. PubMed
- Millqvist E. Cough provocation with capsaicin is an objective way to test sensory hyperreactivity in patients with asthma-like symptoms. Allergy 2000;55:546-50. DOI
- Locock RA. Capsicum. Can Pharm J 1985;118:517-9.
- Mason L, Moore RA, Derry S, et al. Systematic review of topical capsaicin for the treatment of chronic pain. BMJ 2004;328:991. PubMed
- Schmulson MJ, Valdovinos MA, Milke P. Chili pepper and rectal hyperalgesia in irritable bowel syndrome. Am J Gastroenterol 2003;98:1214-5. PubMed
- Surh YJ, Lee SS. Capsaicin in hot chili pepper: carcinogen, co-carcinogen or anticarcinogen? Food Chem Toxicol 1996;34:313-6. PubMed
- Bouraoui A, Brazier JL, Zouaghi H, Rousseau M. Theophylline pharmacokinetics and metabolism in rabbits following single and repeated administration of Capsicum fruit. Eur J Drug Metab Pharmacokinet 1995;20:173-8.
- Hogaboam CM, Wallace JL. Inhibition of platelet aggregation by capsaicin. An effect unrelated to actions on sensory afferent neurons. Eur J Pharmacol 1991;202:129-31. PubMed
- Wang JP, Hsu MF, Teng CM. Antiplatelet effect of capsaicin. Thromb Res 1984;36:497-507. PubMed
- Williams SR, Clark RF, Dunford JV. Contact dermatitis associated with capsaicin: Hunan hand syndrome. Ann Emerg Med 1995;25:713-5. PubMed
- Zollman TM, Bragg RM, Harrison DA. Clinical effects of oleoresin capsicum (pepper spray) on the human cornea and conjunctiva. Ophthalmology 2000;107:2186-9. PubMed
- Bortolotti M, Coccia G, Grossi G, Miglioli M. The treatment of functional dyspepsia with red pepper. Aliment Pharmacol Ther 2002;16:1075-82. PubMed
- Hakas JF Jr. Topical capsaicin induces cough in patient receiving ACE inhibitor. Ann Allergy 1990;65:322-3.
- Rapoport AM, Bigal ME, Tepper SJ, Sheftell FD. Intranasal medications for the treatment of migraine and cluster headache. CNS Drugs 2004;18:671-85. PubMed
- Stjarne P, Rinder J, Heden-Blomquist E, et al. Capsaicin desensitization of the nasal mucosa reduces symptoms upon allergen challenge in patients with allergic rhinitis. Acta Otolaryngol 1998;118:235-9. PubMed
- Levy RL. Intranasal capsaicin for acute abortive treatment of migraine without aura. Headache 1995;35:277.
- Fusco BM, Marabini S, Maggi CA, et al. Preventative effect of repeated nasal applications of capsaicin in cluster headache. Pain 1994;59:321-5. PubMed
- Sicuteri F, Fusco BM, Marabini S, et al. Beneficial effect of capsaicin application to the nasal mucosa in cluster headache. Clin J Pain 1989;5:49-53. PubMed
- Marabini S, Ciabatti PG, Polli G, et al. Beneficial effects of intranasal applications of capsaicin in patients with vasomotor rhinitis. Eur Arch Otorhinolaryngol 1991;248:191-4. PubMed
- Frerick H, Keitel W, Kuhn U, et al. Topical treatment of chronic low back pain with a capsicum plaster. Pain 2003;106:59-64. PubMed
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- Petruzzi, M., Lauritano, D., De Benedittis, M., Baldoni, M., and Serpico, R. Systemic capsaicin for burning mouth syndrome: short-term results of a pilot study. J.Oral Pathol.Med. 2004;33(2):111-114. PubMed
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- Final report on the safety assessment of capsicum annuum extract, capsicum annuum fruit extract, capsicum annuum resin, capsicum annuum fruit powder, capsicum frutescens fruit, capsicum frutescens fruit extract, capsicum frutescens resin, and capsaicin.
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- Busker, R. W. and van Helden, H. P. Toxicologic evaluation of pepper spray as a possible weapon for the Dutch police force: risk assessment and efficacy. Am.J.Forensic Med.Pathol. 1998;19(4):309-316. PubMed
- Sausenthaler, S., Koletzko, S., Schaaf, B., Lehmann, I., Borte, M., Herbarth, O., von Berg, A., Wichmann, H. E., and Heinrich, J. Maternal diet during pregnancy in relation to eczema and allergic sensitization in the offspring at 2 y of age. Am J Clin Nu PubMed
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- Copeland S, Nugent K. Persistent respiratory symptoms following prolonged capsaicin exposure. Int J Occup Environ Med. 2013;4(4):211-5.
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