Forskolin Premium Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Forskolin Premium against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Forskolin Premium is a dietary supplement by Premium Certified with 1 active ingredient. Its ingredients are commonly taken for weight management, asthma and breathing, high blood pressure.Based on those ingredients, 915 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Forskolin (C. forskohlii) root extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Forskolin Premium by Premium Certified
Ask about any prescription or over-the-counter medication and we check it for interactions with Forskolin Premium by Premium Certified — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Forskolin Premium by Premium Certified
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
The stated purpose hasn't been mapped to our evidence data yet.
Why this rating?
- We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Every active ingredient lists its own amount on the label.
Why this rating?
- The label discloses an exact amount for 1 of its 1 active ingredient.
- No proprietary blends here — you can verify the dose of every single component.
At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.
Why this rating?
- 1 of the 1 matched ingredient can interact with medications — Coleus.
- The most serious interaction on file is rated Major.
- Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
- For scale: 916 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.
Why this rating?
- We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
- Pregnancy & breastfeeding safety ratings cover 1 of 1.
- General safety write-ups exist for 1 of 1.
- Remember: this measures how much safety information exists. Thin data is not the same as being safe.
HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Major medication interactions have been identified, and safety information is well characterized.
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 27, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Forskolin Premium, straight from the product label.
| Brand | Premium Certified |
|---|---|
| Barcode (UPC) | 700371880293 |
| Net contents | 60 Veggie Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Jul 27, 2021 |
| DSLD ID | 248604 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Forskolin Premium by Premium Certified, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Forskolin (C. forskohlii) root extract | 500 mg | -- |
Other ingredients: vegetarian Cellulose
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested Use: As a dietary supplement, take two capsules a day. For best results, take one in the morning and one in the afternoon.
Precautions
Warning: Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition, should consult with a physician before taking this or any other dietary supplement.
Warning: Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition, should consult with a physician before taking this or any other dietary supplement.
Keep out of the reach of children.
Do not use this product if outer seal around cap is missing or broken.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Storage
Store at room temperature.
Formulation
Formulated in the USA according to current Good Manufacturing Practice (cGMP) and to the tested ingredient grade, strength and purity of industry Quality Standards.
Absolutely no added fillers or binders. Other ingredients needed to make capsule only.
Vegan Friendly
Formula
Premium quality forskolin with 20% standardization
Pure & natural Forskolin extract
FDA Statement of Identity
Dietary Supplement
Seals/Symbols
Made In USA Not Tested On Animals
General Statements
Please Recycle
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Forskolin Premium by Premium Certified label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Forskolin Premium by Premium Certified
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Forskolin (C. forskohlii) root extract
Interacts with915 drugs
Coleus is a plant from the mint family whose root contains a compound called forskolin, often marketed for weight loss, asthma, and heart health. Whil...
Forskolin (C. forskohlii) root extract monograph & interactionsOther (inactive) ingredients: Vegetarian Cellulose. These complete the product’s ingredient list but are not active constituents.
Forskolin Premium by Premium Certified Drug Interactions
Forskolin Premium contains a single active ingredient, and it has known interactions with 915 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against Forskolin Premium?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Forskolin Premium interact with 915 drugs. Click any drug to see the details.
1 of the 1 ingredient in Forskolin Premium interact with drugs. Each result below shows which ingredient is responsible. Forskolin (C. forskohlii) root extract
Cabozantinib S-malateCabometyx
How Cabozantinib S-malate interacts with Forskolin Premium — through 1 ingredient. Tap an ingredient for the detail:
Forskolin (c. Forskohlii) Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
Read the full Forskolin (c. Forskohlii) Root Extract + Cabozantinib S-malate interactionCaffeine (otc Drug)Molie, Overtime, Vivarin
How Caffeine (otc Drug) interacts with Forskolin Premium — through 1 ingredient. Tap an ingredient for the detail:
Forskolin (c. Forskohlii) Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
Read the full Forskolin (c. Forskohlii) Root Extract + Caffeine (otc Drug) interactionCaffeine (prescription Drug)Caffeine, Dextrophin
How Caffeine (prescription Drug) interacts with Forskolin Premium — through 1 ingredient. Tap an ingredient for the detail:
Forskolin (c. Forskohlii) Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
Read the full Forskolin (c. Forskohlii) Root Extract + Caffeine (prescription Drug) interactionCaffeine , Sodium BenzoateCaffeine and Sodium Benzoate
How Caffeine , Sodium Benzoate interacts with Forskolin Premium — through 1 ingredient. Tap an ingredient for the detail:
Forskolin (c. Forskohlii) Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
Read the full Forskolin (c. Forskohlii) Root Extract + Caffeine , Sodium Benzoate interactionCaffeine, Diphenhydramine, Ergotamine (prescription Drug)Ergodryl
How Caffeine, Diphenhydramine, Ergotamine (prescription Drug) interacts with Forskolin Premium — through 1 ingredient. Tap an ingredient for the detail:
Forskolin (c. Forskohlii) Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
Read the full Forskolin (c. Forskohlii) Root Extract + Caffeine, Diphenhydramine, Ergotamine (prescription Drug) interactionCaffeine, Ergotamine (prescription Drug)Migergot
How Caffeine, Ergotamine (prescription Drug) interacts with Forskolin Premium — through 1 ingredient. Tap an ingredient for the detail:
Forskolin (c. Forskohlii) Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
Read the full Forskolin (c. Forskohlii) Root Extract + Caffeine, Ergotamine (prescription Drug) interactionCaffeine, Ergotamine Tartrate (prescription Drug)Cafergot, Wigraine
How Caffeine, Ergotamine Tartrate (prescription Drug) interacts with Forskolin Premium — through 1 ingredient. Tap an ingredient for the detail:
Forskolin (c. Forskohlii) Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
Read the full Forskolin (c. Forskohlii) Root Extract + Caffeine, Ergotamine Tartrate (prescription Drug) interactionCaffeine, Potassium Salicylate, SalicylamideTrim-Elim
How Caffeine, Potassium Salicylate, Salicylamide interacts with Forskolin Premium — through 1 ingredient. Tap an ingredient for the detail:
Forskolin (c. Forskohlii) Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
Read the full Forskolin (c. Forskohlii) Root Extract + Caffeine, Potassium Salicylate, Salicylamide interactionCalcifediolRayaldee
How Calcifediol interacts with Forskolin Premium — through 1 ingredient. Tap an ingredient for the detail:
Forskolin (c. Forskohlii) Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
Read the full Forskolin (c. Forskohlii) Root Extract + Calcifediol interactionCandesartan CilexetilAmias, Atacand
How Candesartan Cilexetil interacts with Forskolin Premium — through 1 ingredient. Tap an ingredient for the detail:
Forskolin (c. Forskohlii) Root ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, combining coleus with antihypertensive drugs might cause additive blood pressure lowering effects and increase the risk of hypotension.
Read the full Forskolin (c. Forskohlii) Root Extract + Candesartan Cilexetil interactionCandesartan Cilexetil, HydrochlorothiazideAtacand HCT
How Candesartan Cilexetil, Hydrochlorothiazide interacts with Forskolin Premium — through 1 ingredient. Tap an ingredient for the detail:
Forskolin (c. Forskohlii) Root ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, combining coleus with antihypertensive drugs might cause additive blood pressure lowering effects and increase the risk of hypotension.
Read the full Forskolin (c. Forskohlii) Root Extract + Candesartan Cilexetil, Hydrochlorothiazide interactionCangrelorKengreal
How Cangrelor interacts with Forskolin Premium — through 1 ingredient. Tap an ingredient for the detail:
Forskolin (c. Forskohlii) Root ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of coleus and anticoagulant or antiplatelet drugs might increase the risk of bruising and bleeding.
Read the full Forskolin (c. Forskohlii) Root Extract + Cangrelor interactionCannabidiol (prescription Drug)Epidiolex
How Cannabidiol (prescription Drug) interacts with Forskolin Premium — through 1 ingredient. Tap an ingredient for the detail:
Forskolin (c. Forskohlii) Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
Read the full Forskolin (c. Forskohlii) Root Extract + Cannabidiol (prescription Drug) interactionCapivasertibTruqap
How Capivasertib interacts with Forskolin Premium — through 1 ingredient. Tap an ingredient for the detail:
Forskolin (c. Forskohlii) Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
Read the full Forskolin (c. Forskohlii) Root Extract + Capivasertib interactionCapmatinib HydrochlorideTabrecta
How Capmatinib Hydrochloride interacts with Forskolin Premium — through 1 ingredient. Tap an ingredient for the detail:
Forskolin (c. Forskohlii) Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
Read the full Forskolin (c. Forskohlii) Root Extract + Capmatinib Hydrochloride interactionCaptoprilAcepril, Capoten
How Captopril interacts with Forskolin Premium — through 1 ingredient. Tap an ingredient for the detail:
Forskolin (c. Forskohlii) Root ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, combining coleus with antihypertensive drugs might cause additive blood pressure lowering effects and increase the risk of hypotension.
Read the full Forskolin (c. Forskohlii) Root Extract + Captopril interactionCaptopril, HydrochlorothiazideAcezide, Capozide
How Captopril, Hydrochlorothiazide interacts with Forskolin Premium — through 1 ingredient. Tap an ingredient for the detail:
Forskolin (c. Forskohlii) Root ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, combining coleus with antihypertensive drugs might cause additive blood pressure lowering effects and increase the risk of hypotension.
Read the full Forskolin (c. Forskohlii) Root Extract + Captopril, Hydrochlorothiazide interactionCarbamazepineCarbatrol, Carnexiv, Equetro, Tegretol, Tegretol XR
How Carbamazepine interacts with Forskolin Premium — through 1 ingredient. Tap an ingredient for the detail:
Forskolin (c. Forskohlii) Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
Read the full Forskolin (c. Forskohlii) Root Extract + Carbamazepine interactionCarbetapentane Tannate, Chlorpheniramine TannateTussi-12
How Carbetapentane Tannate, Chlorpheniramine Tannate interacts with Forskolin Premium — through 1 ingredient. Tap an ingredient for the detail:
Forskolin (c. Forskohlii) Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
Read the full Forskolin (c. Forskohlii) Root Extract + Carbetapentane Tannate, Chlorpheniramine Tannate interactionCarbetapentane Tannate, Chlorpheniramine Tannate, Ephedrine Tannate, Phenylephrine TannateQuadratuss, Ry Tuss, Rynatuss, Tri Tannate Plus
How Carbetapentane Tannate, Chlorpheniramine Tannate, Ephedrine Tannate, Phenylephrine Tannate interacts with Forskolin Premium — through 1 ingredient. Tap an ingredient for the detail:
Forskolin (c. Forskohlii) Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
Read the full Forskolin (c. Forskohlii) Root Extract + Carbetapentane Tannate, Chlorpheniramine Tannate, Ephedrine Tannate, Phenylephrine Tannate interactionCarbetapentane, Chlorpheniramine, PhenylephrineRicotuss
How Carbetapentane, Chlorpheniramine, Phenylephrine interacts with Forskolin Premium — through 1 ingredient. Tap an ingredient for the detail:
Forskolin (c. Forskohlii) Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
Read the full Forskolin (c. Forskohlii) Root Extract + Carbetapentane, Chlorpheniramine, Phenylephrine interactionCarbetapentane, Chlorpheniramine, Phenylephrine, Phenylpropanolamine, Potassium GuaiacolsulfonateCophene-X
How Carbetapentane, Chlorpheniramine, Phenylephrine, Phenylpropanolamine, Potassium Guaiacolsulfonate interacts with Forskolin Premium — through 1 ingredient. Tap an ingredient for the detail:
Forskolin (c. Forskohlii) Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
Read the full Forskolin (c. Forskohlii) Root Extract + Carbetapentane, Chlorpheniramine, Phenylephrine, Phenylpropanolamine, Potassium Guaiacolsulfonate interactionCariprazine HydrochlorideVraylar
How Cariprazine Hydrochloride interacts with Forskolin Premium — through 1 ingredient. Tap an ingredient for the detail:
Forskolin (c. Forskohlii) Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
Read the full Forskolin (c. Forskohlii) Root Extract + Cariprazine Hydrochloride interactionCarteololCartrol, Ocupress
How Carteolol interacts with Forskolin Premium — through 1 ingredient. Tap an ingredient for the detail:
Forskolin (c. Forskohlii) Root ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, combining coleus with antihypertensive drugs might cause additive blood pressure lowering effects and increase the risk of hypotension.
Read the full Forskolin (c. Forskohlii) Root Extract + Carteolol interactionCarvedilolCoreg, Coreg CR
How Carvedilol interacts with Forskolin Premium — through 1 ingredient. Tap an ingredient for the detail:
Forskolin (c. Forskohlii) Root ExtractAntihypertensive Drugs, Cytochrome P450 2c9 (cyp2c9) Substrates Moderate
Interaction Summary
Theoretically, combining coleus with antihypertensive drugs might cause additive blood pressure lowering effects and increase the risk of hypotension.
Read the full Forskolin (c. Forskohlii) Root Extract + Carvedilol interactionCelecoxibCelebrex, Elyxyb
How Celecoxib interacts with Forskolin Premium — through 1 ingredient. Tap an ingredient for the detail:
Forskolin (c. Forskohlii) Root ExtractCytochrome P450 2c9 (cyp2c9) Substrates Moderate
Interaction Summary
Theoretically, taking coleus may affect drugs metabolized by CYP2C9 and increase the risk of adverse effects or reduce the effectiveness.
Read the full Forskolin (c. Forskohlii) Root Extract + Celecoxib interactionCelecoxib, TramadolSeglentis
How Celecoxib, Tramadol interacts with Forskolin Premium — through 1 ingredient. Tap an ingredient for the detail:
Forskolin (c. Forskohlii) Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2c9 (cyp2c9) Substrates Moderate
Interaction Summary
Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
Read the full Forskolin (c. Forskohlii) Root Extract + Celecoxib, Tramadol interactionCeliprololCelicard
How Celiprolol interacts with Forskolin Premium — through 1 ingredient. Tap an ingredient for the detail:
Forskolin (c. Forskohlii) Root ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, combining coleus with antihypertensive drugs might cause additive blood pressure lowering effects and increase the risk of hypotension.
Read the full Forskolin (c. Forskohlii) Root Extract + Celiprolol interactionCevimelineEvoxac
How Cevimeline interacts with Forskolin Premium — through 1 ingredient. Tap an ingredient for the detail:
Forskolin (c. Forskohlii) Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
Read the full Forskolin (c. Forskohlii) Root Extract + Cevimeline interactionChlorothiazideDiuril
How Chlorothiazide interacts with Forskolin Premium — through 1 ingredient. Tap an ingredient for the detail:
Forskolin (c. Forskohlii) Root ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, combining coleus with antihypertensive drugs might cause additive blood pressure lowering effects and increase the risk of hypotension.
Read the full Forskolin (c. Forskohlii) Root Extract + Chlorothiazide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Forskolin Premium with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Forskolin (C. forskohlii) root extract
Calcium Channel Blockers
Theoretically, combining coleus with calcium channel blockers might increase the coronary vasodilatory effects.
Forskolin, a constituent of coleus, and calcium channel blockers both cause coronary vasodilatory effects.
Nitrates
Theoretically, combining coleus with nitrates might increase the coronary vasodilatory effects.
Forskolin, a constituent of coleus, and nitrates both cause coronary vasodilatory effects.
Anticoagulant/Antiplatelet Drugs
Theoretically, concomitant use of coleus and anticoagulant or antiplatelet drugs might increase the risk of bruising and bleeding.
In vitro and animal research shows that forskolin, a constituent of coleus, can inhibit platelet aggregation and adhesion.
Antihypertensive Drugs
Theoretically, combining coleus with antihypertensive drugs might cause additive blood pressure lowering effects and increase the risk of hypotension.
Animal research shows that forskolin, a constituent of coleus, may lower blood pressure.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, taking coleus may affect drugs metabolized by CYP2C9 and increase the risk of adverse effects or reduce the effectiveness.
Research on the effect of coleus on CYP2C9 is conflicting. Some animal research shows that coleus extract can induce CYP2C9, while in vitro research shows that coleus can inhibit CYP2C9. Until more is known, advise patients that taking coleus might increase or decrease levels of drugs metabolized by CYP2C9.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
In vitro research shows that coleus can activate the nuclear receptor, pregnane X receptor (PXR), which results in increased expression of CYP3A4. Although the clinical significance of this is not known, use caution when considering concomitant use of coleus and other drugs affected by these enzymes.
Warfarin (Coumadin)
Theoretically, taking coleus may affect the metabolism of warfarin and increase the risk of adverse effects or reduce the effectiveness.
Some animal research shows that coleus extract can induce cytochrome P450 2C9 (CYP2C9), an enzyme that metabolizes warfarin. However, other in vitro research shows that coleus can inhibit CYP2C9. Theoretically, taking coleus with drugs metabolized by CYP2C9 might affect drug levels and the risk of adverse effects. Until more is known, advise patients that taking coleus might increase or decrease levels of warfarin.
Brand information
Manufacturer and brand details for Forskolin Premium, from the product label.
Premium Certified
See all Premium Certified products- Name
- Forskolin Premium
- City
- Northbrook
- State
- IL
- ZipCode
- 60062
- Phone Number
- 888-893-1413
- Web Address
- www.forskolinspremium.com
Forskolin Premium by Premium Certified: Common Questions
Does Forskolin Premium by Premium Certified interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Forskolin Premium is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Forskolin Premium’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Forskolin Premium's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 16 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Coleus 16 references
- Baumann G, Felix S, Sattelberger U, Klein G. Cardiovascular effects of forskolin (HL-362) in patients with idiopathic congestiv cardiomyopathy. A comparative study with dobutamine and sodium nitroprusside. J Cardiovasc Pharmacol 1990;16:93-100.
- Kramer W, Thormann J, Kindler M, Schlepper M. Effects of forskolin on left ventricular function in dilated cardiomyopathy. Arzneimittelforschung 1987;37:364-7.
- Bauer K, Dietersdorfer F, Kaspar S, et al. Pharmacodynamic effects of inhaled dry powder formulations of fenoterol and colforsin in asthma. Clin Pharmacol Ther 1993;53:76-83. PubMed
- Christenson JT, Thulesius O, Nazzal MM. The effect of forskolin on blood flow, platelet metabolism, aggregation and ATP release. Vasa 1995;24:56-61.
- Agarwal KC, Zielinski BA, Maitra RS. Significance of plasma adenosine in the antiplatelet activity of forskolin: potentiation by dipyridamole and dilazep. Thromb Haemost 1989;61:106-10. DOI
- Agarwal KC, Parks RE. Forskolin: a potential antimetastatic agent. Int J Cancer 1983;32:801-4. PubMed
- Almeida, F. C. and Lemonica, I. P. The toxic effects of Coleus barbatus B. on the different periods of pregnancy in rats. J Ethnopharmacol 2000;73(1-2):53-60. PubMed
- Ding, X. and Staudinger, J. L. Induction of drug metabolism by forskolin: the role of the pregnane X receptor and the protein kinase a signal transduction pathway. J Pharmacol Exp Ther 2005;312(2):849-856. PubMed
- Staudinger, J. L., Ding, X., and Lichti, K. Pregnane X receptor and natural products: beyond drug-drug interactions. Expert.Opin Drug Metab Toxicol 2006;2(6):847-857. PubMed
- van Hecke, E., Hindryckx, P., Geuns, J. M., and Devriese, E. Airborne contact dermatitis from coleus in a housewife. Contact Dermatitis 1991;25(2):128-129. PubMed
- Schlepper, M., Thormann, J., and Mitrovic, V. Cardiovascular effects of forskolin and phosphodiesterase-III inhibitors. Basic Res Cardiol 1989;84 Suppl 1:197-212. PubMed
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